Repositorio Dspace

Envíos recientes

02.02.01. Investigación y comunicación científica: Envíos recientes

  • Effectiveness and Safety of Sacituzumab Govitecan in Real-World Clinical Practice in Patients with Metastatic Triple-Negative and HR+/HER2-Negative Breast Cancer 
    Lago-Ballester, Fernando; Martínez-Orea, Adrian; Laorden-Carrasco, Ana; Díaz-Carrasco, María-Sacramento; Titos-Arcos, José-Carlos; Mira-Sirvent, María-del-Carmen; Luengo-Gil, Ginés; Martínez-Penella, Mónica (MDPI, 2025-08-23)
    Background/Objectives: Sacituzumab govitecan (SG) is an antibody-drug conjugate targeting Trop-2 that has demonstrated clinical benefits in randomised trials for patients with metastatic triple-negative breast cancer (mTNBC) ...
  • Differential Role of NKG2A/HLA-E Interaction in the Outcomes of Bladder Cancer Patients Treated with M. bovis BCG or Other Therapies 
    Ruiz-Lorente, Inmaculada; Gimeno-Arias, Lourdes; López-Abad, Alicia; López-Cubillana, Pedro; Fernández-Aparicio, Tomás; Asensio-Egea, Lucas-Jesús; Moreno-Avilés, Juan; Doñate-Íñiguez, Gloria; Guzmán-Martínez-Valls, Pablo-Luis; Server, Gerardo; Ferri-Ñíguez, Belén; Campillo, José-Antonio; Martínez-Sánchez, María-Victoria; Minguela-Puras, Alfredo (MDPI, 2025-01-10)
    Background: Immunotherapy is gaining great relevance in both non-muscle-invasive bladder cancer (NMIBC), with the use of bacille Calmette-Guerin (BCG), and in muscle-invasive BC (MIBC) with anti-checkpoint therapies blocking ...
  • Long-term effectiveness, adherence and safety of twice-yearly paliperidone-palmitate long acting-injectable in patients with schizophrenia in Europe: 2-year mirror-image data from the paliperdone-2 per year study (P2Y) 
    Manchado-Perero, Sofía; Rodríguez-Lorente, Ana; García-Pérez, Alba-María; García, Guillermo-Isidro; Forcén-Muñoz, Luis-Alberto; Ovejero-García, Sanitago; Sáez-Povedano, Rocío; González-Galdámez, Ana-Luisa; Mata-Iturralde, Laura; Ramírez-Bonilla, Mariluz; Fuentes-Pérez, Paloma; Ovejas-Catalán, Claudia; Suárez-Pinilla, Paula; Fernández-Abascal, Blanca; Omana-Colmenares, Miguel; Campos-Navarro, María-Pilar; Baca-García, Enrique; Lara-Fernández, Ana; Benavente-López, Sergio; Raya-Platero, Alberto; Barberán-Navalon, Miguel; Sánchez-Alonso, Sergio; Vázquez-Bourgon, Javier; Pappa, Sofia; García-Carmona, Juan-Antonio (FRONTIERS MEDIA SA, 2025-03-04)
    BACKGROUND: LAIs with longer dosing intervals appear to be associated with improved clinical outcomes and added real-world benefits in the management of schizophrenia. Paliperidone palmitate six-monthly (PP6M) LAI provides ...
  • Association between human leukocyte antigen E expression and outcomes in solid tumors: a systematic review and meta-analysis 
    Benítez-Fuentes, Javier-David; Arcilla, Jorge-Bartolome; Lázaro-Sánchez, Antonio-David; de-Luna-Aguilar, Alicia; Mohamed, Kauzar-Mohamed; Guevara-Hoyer, Kissy; Ballestín-Martínez, Pablo; Borregón-Rivilla, Miguel; Fernández-Arias, Asia; Sánchez-Ramon, Silvia; Ocaña, Alberto (FRONTIERS MEDIA SA, 2025-02-24)
    BACKGROUND: Immunotherapy has gained momentum with the discovery of novel antibodies targeting immunosuppressive proteins. HLA-E, a non-classical major histocompatibility complex class I (MHC-I) protein, exhibits ...
  • Unleashing the power of CAR-M therapy in solid tumors: a comprehensive review 
    Morva, Ahsen; Arroyo-Rodríguez, Ana-Belén; Andreeva, Liudmila; Tapia-Abellán, Ana; Luengo-Gil, Ginés (FRONTIERS MEDIA SA, 2025-06-12)
    Chimeric antigen receptor (CAR) macrophage therapy represents a promising new frontier in cancer immunotherapy, with the potential to overcome the limitations of CAR-T cell approaches, particularly in solid tumours. This ...
  • The Gulliver syndrome: a conceptual framework to address therapeutic inertia in patients with borderline cardiovascular risk profiles (vol 12, 1652447, 2025) 
    López-Gil, José-Francisco; Abellán-Huerta, José; Abellán-Alemán, José (FRONTIERS MEDIA SA, 2025-11-06)
    [This corrects the article DOI: 10.3389/fcvm.2025.1652447.].
  • The Gulliver syndrome: a conceptual framework to address therapeutic inertia in patients with borderline cardiovascular risk profiles 
    López-Gil, José-Francisco; Abellán-Huerta, José; Abellán-Alemán, José (FRONTIERS MEDIA SA, 2025-08-14)
    We propose a novel clinical construct, the "Gulliver syndrome", to describe the scenario in which multiple, mildly elevated cardiovascular risk factors (CVRFs) coexist within an individual and together result in a significantly ...
  • One-Year Evaluation of Paliperidone Palmitate 6-Monthly: Satisfaction and Perceived Effectiveness Among Patients, Relatives, and Clinicians 
    Manchado-Perero, Sofía; Rodríguez-Lorente, Ana; García-Pérez, Alba-María; García, Guillermo-Isidro; Forcén-Muñoz, Luis-Alberto; Ovejero, Santiago; Sáez-Povedano, Rocío; González-Galdámez, Ana-Luisa; Mata-Iturralde, Laura; Ramírez-Bonilla, Mariluz; Fuentes-Pérez, Paloma; Ovejas-Catalán, Claudia; Suárez-Pinilla, Paula; Fernández-Abascal-Puente, Blanca; Colmenares, Miguel-Omana; Campos-Navarro, María-Pilar; Baca-García, Enrique; Lara-Fernández, Ana; Benavente-López, Sergio; Raya-Platero, Alberto; Barberán-Navalon, Miguel; Sánchez-Alonso, Sergio; Vázquez-Bourgon, Javier; Pappa, Sofia; García-Carmona, Juan-Antonio (DOVE MEDICAL PRESS LTD, 2025-05)
    BACKGROUND: Patient satisfaction and perceived treatment effectiveness play a critical role in healthcare outcomes and overall well-being. Understanding patient experiences can help identify barriers to adherence and guide ...
  • Protocol for an open labelled observational study in children & adolescents with severe asthma with an eosinophilic phenotype treated with mepolizumab (CASAM) 
    Gupta, Atul; de-Mir-Messa, Inés; Valverde-Molina, José; Murray, Clare-S; Moral, Luis; Torres-Borrego, Javier; Pike, Katharine; Díaz-Izquierdo, Ana; Martínez-Cañavate, Ana; Nagakumar, Prasad; Cook, James; Gupta, Latika (PUBLIC LIBRARY SCIENCE, 2025-12-19)
    INTRODUCTION: Children with severe eosinophilic asthma are at an increased risk of severe exacerbations, medication side effects, impaired lung function, and significantly reduced quality of life. The advent of biologic ...
  • Impact of bictegravir/emtricitabine/tenofovir alafenamide on health-related quality of life and economic outcomes in HIV care: Substudy of the BIC-NOW clinical trial 
    Sequera-Arquelladas, Sergio; Vivancos, María-J; Vinuesa, David; Collado, Antonio; de-los-Santos, Ignacio; Sorni, Patricia; Cabello-Clotet, Noemi; Montero, Marta; Ramos-Font, Carlos; Terron, Alberto; Galindo, María-José; Martínez-Madrid, Onofre; Ryan, Pablo; Omar-Mohamed, Mohamed; Albendin-Iglesias, Helena; Javier, Rosario; Romero, Alberto; García-Vallecillos, Coral; Calleja, Miguel-Ángel; Hidalgo-Tenorio, Carmen (PUBLIC LIBRARY SCIENCE, 2025-09-22)
    BACKGROUND: The BICNOW clinical trial evaluated the effectiveness, safety, satisfaction, adherence to treatment, and retention in the system of a rapid initiation strategy with bictegravir/emtricitabine/tenofovir alafenamide ...
  • Development of a radio thin-layer chromatography scanner: Design and qualification 
    Chivato-Martín-Falquina, Tomás; Miñana-Olmo, Elena; Alonso-García, Ángela; Rosezky, Matthias (SPRINGERNATURE, 2025-12-19)
    BACKGROUND: Radiochemical Purity (RCP) assessment is a fundamental quality control parameter in radiopharmaceutical production. Thin-Layer Chromatography (TLC) using a radio-TLC scanner is the most common method employed ...
  • Hypomethylation of the MEG8:Int2-DMR in patients with pathogenic PLAG1 variants suggests new role of the chr14q32 imprinting cluster in Silver-Russell syndrome 
    D'angelo, Emilia; Pignata, Laura; Cecere, Francesco; Vimercati, Alessandro; Cubellis, María-Vittoria; Saadat, Abu; Giaccari, Carlo; Thibaud, Nathalie; Eggermann, Thomas; Fernández-Fructuoso, Jose-Ramón; Russo, Silvia; Netchine, Irene; Cerrato, Flavia; Riccio, Andrea; Brioude, Frederic (BMC, 2025-11-23)
    BACKGROUND: Silver-Russell syndrome (SRS) is a clinically and genetically heterogeneous imprinting disorder. The most common molecular defects are loss of methylation of the H19/IGF2:IG-DMR on chromosome 11p15.5, followed ...
  • Severe Paediatric Asthma Collaborative in Europe: real-world data on children on biologics 
    Liu, Norrice-M; Pijnenburg, Marielle-W; Deschildre, Antoine; de-Mir-Messa, Inés; Adalen, Sigve; Amat, Flore; Antonino, Luna; Bierme, Priscille; Bravo-López, Maynor; Carlsen, Karin-C-L; Carraro, Silvia; Cros, Pierrick; Delestrain, Celine; Díaz-García, Carolina; Epaud, Ralph; Fenu, Grazia; Ferraro, Valentina-A; Fleming, Louise; Hanssens, Laurence; Heine, Anouk; Labouret, Geraldine; Leóni, María-Chiara; Licari, Amelia; Lombardi, Enrico; López-Neyra, Alejandro; Marguet, Christophe; Mazenq, Julie; Pérez-Tarazona, Santiago; Ramos-Díaz, Juan-Carlos; Schweitzer, Cyril; Spada, Elena; Valverde-Molina, José; Verhulst, Stijn; Wanin, Stephanie; Rusconi, Franca (EUROPEAN RESPIRATORY SOC JOURNALS LTD, 2025-05)
    INTRODUCTION: Real-world data on children with severe asthma is scarce. We report characteristics of children with severe asthma already on biologics, enrolled in the Severe Paediatric Asthma Collaborative in Europe, a ...
  • Does Combining a Mobile Dose Calculation App with a Continuous Insulin Infusion System Improve Glycemic Control and Quality of Life Compared with a Hybrid System in Patients with Type 1 Diabetes? A Descriptive Open-Label Sequential Study 
    Pujante-Alarcón, Pedro; Álvarez, Elias-Delgado; Lambert-Goitia, Carmen; Moreira-Rodríguez, Manuela; Urbon, Lidia; Maldonado, Alfonso; García, Susana; Bau-Serrallonga, Nuria; Ruiz-Avino, Lidia; Ruiz-Palomar, Juan-M; González-López, Javier; Navarro-Hoyas, Clara-Isabel; Corcoy, Rosa; Martínez-Raimond, Teresa; Lainez-López, María; Soldevilla-Madorell, Berta; Hernández, Marta; Kyriakos, Georgios; Cotovad-Bellas, Laura; Girbes-Borras, Juan; Simo-Servant, Olga; Megía-Colet, Ana; Serrano-García, Cristina; Contreras, Cristina; Rebollo-Roman, Ángel; Diez, May; Veladesojo, Amaya; Andujar, Paula; Diez, Alberto; Abellán-Galiana, Pablo; Pla-Peris, Begoña; Fernández, Elsa; Ferrer, Marta; Gómez-Alfonso, Francisco-Javier; Menéndez-Torre, Edelmiro-Luis (MARY ANN LIEBERT, INC, 2025-10)
    Introduction: Achieving optimal glycemic control in patients with type 1 diabetes mellitus (PwT1DM) is essential to prevent complications. Continuous subcutaneous insulin infusion (CSII) systems combined with continuous ...
  • Real-World Impact of Calcipotriol/Betamethasone Dipropionate Aerosol Foam on Quality of Life in Patients With Plaque Psoriasis: A Prospective Observational Study 
    Torres, Tiago; Martorell, Antonio; Leal-Filipe, Paulo; Soria, Caridad; Mota, Fernando; Pardo, José; Ribera, Miquel; Ruiz-Villaverde, Ricardo (WILEY, 2025-01)
  • Fatigue, Physical Symptoms, Psychological Distress, and Use of Integrative Medicine in Patients With Advanced Cancer 
    Calderón, Caterina; Muñoz-Sánchez, M-Mar; Peña-López, Jesús; López-Ceballos, M-Helena; Fernández-Montes, Ana; Asensio-Martínez, Elena; Carrillo-Vicente, Raul; Gustems, Marina; Jiménez-Fonseca, Paula (WILEY, 2025-01)
  • Hydroxychloroquine in patients with systemic lupus erythematosus: how much is enough? 
    Ruiz-Irastorza, Guillermo; Paredes-Ruiz, Diana; Arizpe, Fernando; Campos-Rodríguez, Valerio; Moreno-Torres, Victor; Amo, Laura; Ruiz-Arruza, Ioana; Martín-Iglesias, Daniel (BMJ PUBLISHING GROUP, 2025-02)
    OBJECTIVE: To assess the daily and weight-adjusted dosages of hydroxychloroquine (HCQ) and the effects on long-term remission in the Lupus-Cruces cohort. METHODS: Observational study of routine clinical care data. We ...
  • Segmentation Techniques Applied to CNNs for Cervical Cancer Classification 
    Ortiz-González, Ana; Martínez-Espana, Raquel; Morales-García, Juan; Imbernon, Baldomero; Martínez-Mas, José; Álvarez, Mauricio-A; Romero, Óscar-David; Martínez-Cendán, Juan-Pedro; Bueno-Crespo, Andrés (IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC, 2025)
  • Characterization of thrombosis risk in ambulatory patients with cancer: results of the observational, prospective, multicenter CARTAGO study 
    Trujillo-Santos, Javier; García-Escobar, Ignacio; Salgado, Mercedes; Araujo, Antonio; Martínez-de-Castro, Eva; Molina, Raquel; Castellón-Rubio, Victoria-Eugenia; Domenech, Pere; Gallardo, Enrique; Colome, Esteve; Torres, Ferran; Benítez-Montanez, José-Carlos; Porta, Rut; Lobo-de-Mena, Miriam; Malheiro, Mariana; Font, Carme; Brozos-Vázquez, Elena; Garicano, Fernando; Sapena, Victor; Costa, Ana-Lucía; Albuquerque, Ana-Cristina; Cerezuela-Fuentes, Pablo; CARTAGO-Study-Grp, Sara (OXFORD UNIV PRESS, 2025-08-04)
    BACKGROUND: Venous thromboembolism (VTE) is one of the leading causes of death in patients with cancer. Currently, there is a need to develop an easily applicable risk model that can identify patients who will benefit from ...
  • Arrhythmic genotypes in dilated cardiomyopathy and risk of advanced heart failure 
    Mora-Ayestaran, Nerea; Ochoa, Juan-Pablo; Gómez-González, Cristina; Navarro-Peñalver, Marina; Gallego-Delgado, María; Larrañaga-Moreira, José-M; Robles-Mezcua, Ainhoa; Basurte-Elorz, María-Teresa; Rodríguez-Palomares, José-Fernando; Climent-Paya, Vicente; Jiménez-Jaimez, Juan; Mogollon-Jiménez, María-Victoria; García-Granja, Pablo-Elpidio; García-Álvarez, Ana; Peña-Peña, María-Luisa; Álvarez-Barredo, María; Ripoll-Vera, Tomas; Palomino-Doza, Julián; Bayes-Genis, Antoni; Tiron, Coloma; Fernández, Ana-Isabel; Sabater-Molina, María; Toranzo, Inés; Crespo-Leiro, María-G; Doncel-Abad, Victoria; Lacuey-Lecumberri, Gemma; Limeres-Freire, Javier; I; Cabrera-Borrego, Eva; Kounka-Ait-El-Maalem, Zineb; Vilches, Silvia; González-López, Esther; Villacorta, Eduardo; García-Pinilla, José-M; Barriales-Villa, Roberto; Gimeno-Blanes, Juan-Ramón; García-Pavia, Pablo; Domínguez, Fernando (OXFORD UNIV PRESS, 2025-12-22)
    BACKGROUND AND AIMS: Certain genetic forms of dilated cardiomyopathy (DCM) entail a higher arrhythmic risk. It is unknown whether DCM patients with high-risk arrhythmic genotypes also develop more advanced heart failure ...

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