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  • Intake of individual fatty acids and risk of prostate cancer in the European prospective investigation into cancer and nutrition 
    Pérez-Cornago, Aurora; Huybrechts, Inge; Appleby, Paul-N; Schmidt, Julie-A; Crowe, Francesca-L; Overvad, Kim; Tjonneland, Anne; Kuehn, Tilman; Katzke, Verena-A; Trichopoulou, Antonia; Karakatsani, Anna; Peppa, Eleni; Grioni, Sara; Palli, Domenico; Sacerdote, Carlotta; Tumino, Rosario; Bueno-de-Mesquita, Bas; Larrañaga, Nerea; Sánchez, María-José; Quirós, José-Ramón; Ardanaz, Eva; Chirlaque-López, María-Dolores; Agudo, Antonio; Bjartell, Anders; Wallstrom, Peter; Chajes, Veronique; Tsilidis, Konstantinos-K; Aune, Dagfinn; Riboli, Elio; Travis, Ruth-C; Key, Timothy-J (Wiley, 01/01/2020)
    The associations of individual dietary fatty acids with prostate cancer risk have not been examined comprehensively. We examined the prospective association of individual dietary fatty acids with prostate cancer risk ...
  • Weight change in middle adulthood and risk of cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort 
    Christakoudi, Sofia; Pagoni, Panagiota; Ferrari, Pietro; Cross, Amanda-J; Tzoulaki, Ioanna; Muller, David; Weiderpass, Elisabete; Freisling, Heinz; Murphy, Neil; Dossus, Laure; Turzanski-Fortner, Renee; Agudo, Antonio; Overvad, Kim; Pérez-Cornago, Aurora; Key, Timothy-J; Brennan, Paul; Johansson, Mattias; Tjonneland, Anne; Halkjaer, Jytte; Boutron-Ruault, Marie-Christine; Artaud, Fanny; Severi, Gianluca; Kaaks, Rudolf; Schulze, Matthias-B; Bergmann, Manuela-M; Masala, Giovanna; Grioni, Sara; Simeon, Vittorio; Tumino, Rosario; Sacerdote, Carlotta; Skeie, Guri; Rylander, Charlotta; Borch, Kristin-Benjaminsen; Quirós, José-Ramón; Rodríguez-Barranco, Miguel; Chirlaque-López, María-Dolores; Ardanaz, Eva; Amiano, Pilar; Drake, Isabel; Stocks, Tanja; Haggstrom, Christel; Harlid, Sophia; Ellingjord-Dale, Merete; Riboli, Elio; Tsilidis, Konstantinos-K (Wiley, 01/04/2021)
    Obesity is a risk factor for several major cancers. Associations of weight change in middle adulthood with cancer risk, however, are less clear. We examined the association of change in weight and body mass index (BMI) ...
  • 13th Post-ECTRIMS Meeting: review of the new developments presented at the 2020 ECTRIMS Congress (I) 
    Fernández, Oscar; Montalbán, Xavier; Aladro, Yolanda; Alonso, Ana; Arroyo, Rafael; Calles, Carmen; Castillo-Trivino, T; Comabella, Manuel; Costa-Frossard, Lucienne; Forero, Lucía; Ginestal, Ricardo; Landete, Lamberto; Llaneza, Miguel; Llufriu, Sara; Martínez, Luisa (REVISTA DE NEUROLOGIA, 01/06/2021)
    Introduction. On 4 and 5 November 2022, Madrid hosted the 15th edition of the Post-ECTRIMS Meeting, where neurologists specialised in multiple sclerosis outlined the latest developments presented at the 2022 ECTRIMS Congress, ...
  • 15th Post-ECTRIMS Meeting: a review of the latest developments presented at the 2022 ECTRIMS Congress (Part I) 
    Fernández, Oscar; Montalbán, Xavier; Agüera, Eduardo; Aladro, Yolanda; Alonso, Ana; Arroyo, Rafael; Brieva, Luis; Calles, Carmen; Costa-Frossard, Lucienne; Eichau, Sara; Garcia-Dominguez, José-M; Hernández, Miguel-A; Landete, Lamberto; Llaneza-Sara-Llufriu, Miguel; Mec, (REVISTA DE NEUROLOGIA, 01/07/2023)
    Objective Idiopathic central precocious puberty (CPP) precipitates epiphyseal fusion of growth plates in long bones, leading to reduced adult stature. Gonadotropin-releasing hormone analogues (GnRHa) are the treatment of ...
  • A Randomized Trial of Dolutegravir Plus Darunavir/Cobicistat as a Switch Strategy in HIV-1-Infected Patients With Resistance to at Least 2 Antiretroviral Classes 
    Santos, José-R; Domingo, Pere; Portilla, Joaquín; Gutiérrez, Félix; Imaz, Arkaitz; Vilchez, Helem; Curran, Adrián; Valcarce-Pardeiro, Nieves; Payeras, Antoni; Bernal-Morell, Enrique; Montero-Alonso, Marta; Yzusqui, Miguel; Clotet, Bonaventura; Videla, Sebastián; Molto, José; Par, (OXFORD UNIV PRESS INC, 01/11/2023)
    Background. Suppressed patients with drug-resistant HIV-1 require effective and simple antiretroviral therapy to maintain treatment adherence and viral suppression.Methods. This randomized, open-label, noninferiority, ...
  • Diet-wide association study of 92 foods and nutrients and lung cancer risk in the European Prospective Investigation into Cancer and Nutrition study and the Netherlands Cohort Study 
    Heath, Alicia-K; Muller, David; van-den-Brandt, Piet-A; Critselis, Elena; Gunter, Marc-J; Vineis, Paolo; Weiderpass, Elisabete; Boeing, Heiner; Ferrari, Pietro; Merritt, Melissa-A; Rostgaard-Hansen, Agnetha-Linn; Tjonneland, Anne; Overvad, Kim; Katzke, Verena-A; Srour, Bernard; Masala, Giovanna; Sacerdote, Carlotta; Ricceri, Fulvio; Pasanisi, Fabrizio; Bueno-de-Mesquita, Bas; Downward, George-S; Skeie, Guri; Sandanger, Torkjel-Manning; Crous-Bou, Marta; Rodríguez-Barranco, Miguel; Amiano, Pilar; Huerta-Castaño, José-María; Ardanaz, Eva; Drake, Isabel; Johansson, Mikael; Johansson, Ingegerd; Key, Tim; Papadimitriou, Nikos; Riboli, Elio; Tzoulaki, Ioanna; Tsilidis, Konstantinos-K (Wiley, 01/12/2022)
    It is unclear whether diet, and in particular certain foods or nutrients, are associated with lung cancer risk. We assessed associations of 92 dietary factors with lung cancer risk in 327-790 participants in the European ...
  • Alpha retinal ganglion cells in pigmented mice retina: number and distribution 
    Gallego-Ortega, Alejandro; Norte-Muñoz, María; Di-Pierdomenico, Johnny; Avilés-Trigueros, Marcelino; de-la-Villa, Pedro; Valiente-Soriano, Francisco-Javier; Vidal-Sanz, Manuel (FRONTIERS MEDIA SA, 01/12/2022)
    BackgroundUp to 30% of breast cancer (BC) patients treated with neoadjuvant chemotherapy (NCT) will relapse. Our objective was to analyze the predictive capacity of several markers associated with immune response and cell ...
  • A novel and efficient tandem CD19-and CD22-directed CAR for B cell ALL 
    Zanetti, Samanta-Romina; Velasco-Hernández, Talia; Gutiérrez-Agüera, Francisco; Díaz, Victor-M; Romecin, Paola-Alejandra; Roca-Ho, Heleia; Sánchez-Martínez, Diego; Tirado, Néstor; Baroni, Matteo-Libero; Petazzi, Paolo; Torres-Ruiz, Raúl; Molina, Óscar; Bataller, Alex (CELL PRESS, 02/02/2022)
    CD19-directed chimeric antigen receptor (CAR) T cells have yielded impressive response rates in refractory/relapse B cell acute lymphoblastic leukemia (B-ALL); however, most patients ultimately relapse due to poor CAR T ...
  • A Novel Substituted Benzo[g]quinoxaline-Based Cyclometalated Ru(II) Complex as a Biocompatible Membrane-Targeted PDT Colon Cancer Stem Cell Agent 
    Marco, Alicia; Kasparkova, Jana; Bautista, Delia; Kostrhunova, Hana; Cutillas, Natalia; Markova, Lenka; Novohradsky, Vojtech; Ruiz, José; Brabec, Viktor (AMER CHEMICAL SOC, 02/12/2024)
    Herein, we describe and investigate biological activity of three octahedral ruthenium(II) complexes of the type [Ru(C boolean AND N)(phen)2]+, RuL1-RuL3, containing a pi-expansive cyclometalating substituted benzo[g]quinoxaline ...
  • A multimodal approach to detect and monitor early lung disease in cystic fibrosis 
    Mondéjar-López, Pedro; Horsley, Alexander; Ratjen, Felix; Bertolo, Silvia; de-Vicente, Helene; Asensio-de-la-Cruz, Oscar (TAYLOR & FRANCIS LTD, 03/06/2021)
    Introduction: In the early stages, lung involvement in cystic fibrosis (CF) can be silent, with disease progression occurring in the absence of clinical symptoms. Irreversible airway damage is present in the early stages ...
  • A Body Shape Index (ABSI) achieves better mortality risk stratification than alternative indices of abdominal obesity: results from a large European cohort 
    Christakoudi, Sofia; Tsilidis, Konstantinos-K; Muller, David-C; Freisling, Heinz; Weiderpass, Elisabete; Overvad, Kim; Soederberg, Stefan; Haeggstroem, Christel; Pischon, Tobias; Dahm, Christina-C; Zhang, Jie; Tjonneland, Anne; Halkjaer, Jytte; MacDonald, Conor; Boutro, (NATURE PORTFOLIO, 03/09/2020)
    Abdominal and general adiposity are independently associated with mortality, but there is no consensus on how best to assess abdominal adiposity. We compared the ability of alternative waist indices to complement body mass ...
  • An opportunity to emphasize the relevance of laboratory medicine 
    Santamaria-González, María; Ruiz-Mínguez, María-Ángels; Arrebola-Ramírez, María-Monsalud; Filella-Pla, Xavier; Torrejón-Martínez, María-José; Morell-García, Daniel; Castaño-López, Miguel-Ángel; Allue-Palacin, Juan-Antonio; Albaladejo-Otón, María-Dolores; Giménez, G (WALTER DE GRUYTER GMBH, 04/08/2021)
    Objectives Clinical practice guidelines (CPGs) are recommendations based on a systematic review of scientific evidence that are intended to help healthcare professionals and patients make the best clinical decisions. CPGs ...
  • Adult syndromology: challenges, opportunities and perspectives 
    Schmetz, Ariane; Ballesta-Martínez, María-Juliana; Isidor, Bertrand; Sousa, Ana-Berta; Wieczorek, Dagmar; Bramswig, Nuria-C (WALTER DE GRUYTER GMBH, 05/06/2024)
    Clinical geneticists and syndromologists have traditionally focused on identifying syndromes in children. However, there is a growing acknowledgment of the need to describe adult phenotypes. This article provides an overview ...
  • Adult height in girls with idiopathic central precocious puberty treated with triptorelin 
    Corripio, Raquel; Soriano-Guillen, Leandro; Herrero, Francisco-Javier; Castro-Feijoo, Lidia; Escribano, Aranzazu; Sol-Ventura, Paula; Espino, Rafael; Vela, Amaia; Labarta, José-Ignacio; Spanish-PUBERE-Grp, Jesús; Argente, Jesús (FRONTIERS MEDIA SA, 05/12/2024)
    BackgroundParkinson's disease (PD) is a progressive neurodegenerative disorder, diagnosed according to the clinical criteria that occur in already advanced stages of PD. The definition of biomarkers for the early diagnosis ...
  • A crowdsourcing database for the copy-number variation of the Spanish population 
    López-López, Daniel; Roldán, Gema; Fernández-Rueda, José; Bostelmann, Gerrit; Carmona, Rosario; Aquino, Virginia; Perez-Florido, Javier; Ortuño, Francisco; Pita, Guillermo; Núñez-Torres, Rocío; González-Neira, Anna; Pena-Chilet, María; Dopazo, Joaquín (BMC, 09/03/2023)
    Background Despite being a very common type of genetic variation, the distribution of copy-number variations (CNVs) in the population is still poorly understood. The knowledge of the genetic variability, especially at the ...
  • A cost-effectiveness analysis of hypertrophic cardiomyopathy sudden cardiac death risk algorithms for implantable cardioverter defibrillator decision-making 
    Green, Nathan; Chen, Yang; O'Mahony, Constantinos; Elliott, Perry-M; Barriales-Villa, Roberto; Monserrat, Lorenzo; Anastasakis, Aris; Biagini, Elena; Gimeno-Blanes, Juan-Ramón; Limongelli, Giuseppe; Pavlou, Menelaos; Omar, Rumana-Z (OXFORD UNIV PRESS, 09/10/2023)
    Aims To conduct a contemporary cost-effectiveness analysis examining the use of implantable cardioverter defibrillators (ICDs) for primary prevention in patients with hypertrophic cardiomyopathy (HCM).Methods A discrete-time ...
  • Evaluation of the impact of the Spanish consensus document on the approach to osteoarticular infections in Spain through the Paediatrics Osteoarticular Infections Network (RIOPED); [Evaluación del impacto del Documento de Consenso español sobre el abordaj 
    Núñez-Cuadros, Esmeralda; Calvo-Rey, Cristina; Saavedra-Lozano, Jesús; Alcobendas-Rueda, Rosa; Clemente-Garulo, Daniel; Sanz-Santaeufemia, F-José; Martínez-Campos, Leticia; Tagarro-García, Alfredo; Fontecha, César-G; Melendo-Pérez, Susana; Camacho-Lovillo (ELSEVIER, 10.1016j.a)
    Introduction: In 2014 the Consensus Document produced by the Spanish Paediatric Societies (SEIP-SERPE-SEOP) was published to help in the diagnosis and treatment of osteoarticular infections (OAI). In 2015 the RIOPed was ...
  • Global overview of the management of acute cholecystitis during the COVID-19 pandemic (CHOLECOVID study) 
    Spiers, Harry-V-M; Kouli, Omar; Ahmed, Waheed-U; Varley, Rebecca; Argus, Leah; McLean, Kenneth-A; Kamarajah, Sivesh-K; Coe, Peter; Griffiths, E; Chan, Anthony-KC; Macutkiewicz, Christian; Jamdar, Saurabh; Wilson, Michael; Toogood, Giles; Siriwardena, Ajit (OXFORD UNIV PRESS, 10.1093bjs)
    Background: This study provides a global overview of the management of patients with acute cholecystitis during the initial phase of the COVID-19 pandemic. Methods: CHOLECOVID is an international, multicentre, observational ...
  • International Lower Limb Collaborative Paediatric subpopulation analysis (INTELLECT-P) study: multicentre, international, retrospective audit of paediatric open fractures 
    Allan, Anna-Y; Berner, Juan-E; Chan, James-K; Gardiner, Matthew-D; Nanchahal, Jagdeep; Jain, Abhilash; Navia, A; Tejos, R; Ortega-Briones, A; Rakhorst, HA; Nolan, G; Samarendra, H; Mohan, A; Cooper, K; Skillman, J; Kennedy, A; Qureshi, A; Wallis, K; Harry (OXFORD UNIV PRESS, 10.1093bjs)
  • Use of risk chart algorithms for the identification of psoriatic arthritis patients at high risk for cardiovascular disease: findings derived from the project CARMA cohort after a 7.5-year follow-up period 
    Polo-y-La-Borda, Jessica; Castañeda, Santos; Heras-Recuero, Elena; Sánchez-Alonso, Fernando; Plaza, Zulema; García-Gómez, Carmen; Ferraz-Amaro, Ivan; Sánchez-Costa, Jesús-Tomás; Sánchez-González, Olga-Carmen; Turrión-Nieves, Ana-Isabel; Pérez-Alcalá, Ana| (BMJ PUBLISHING GROUP, 10.1136rmd)
    Objective: To assess the predictive value of four cardiovascular (CV) risk algorithms for identifying high-risk psoriatic arthritis (PsA) patients. Methods: Evaluation of patients with PsA enrolled in the Spanish prospective ...