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Envíos recientes

02.02.01. Investigación y comunicación científica: Envíos recientes

  • Characterization and Prognostic Impact of Fascin Expression in the Tumor Microenvironment of Triple-Negative Breast Cancer: Clues for a Tailored Therapy 
    Pérez-Parra, David; Postigo-Corrales, Fátima; Cruz, Andreia-Filipa; Sánchez-Espinosa, Alberto; Acosta-Ortega, Jesús-María; Carrillo-Vicente, Raul; López-Abellán, María-Dolores; Conesa-Zamora, Pablo; Luengo-Gila, Gines; Hurtado-Lopez, Ana-María (ELSEVIER SCIENCE INC, 2026-02)
    Triple-negative breast cancer (TNBC) represents 10% to 15% of all cases with breast cancer, predominantly affecting younger women. Due to the absence of hormone receptors and human epidermal growth factor receptor 2 ...
  • Defining ascending aorta dilatation in pediatric bicuspid aortic valve: Comparison of known classical and new z-score nomograms, and anthropometric parameters indexing for its assessment. 
    Freixa-Benavente, Andrea; Juzga-Corrales, Carolina; Ayerza-Casas, Ariadna; Figueras-Coll, Marc; Escriba-Bori, Silvia; Plata-Izquierdo, Beatriz; Collell, Rosa; González-Marín, María-Arantzazu; Siurana, José-Manuel; Sorli-García, Moises; Albert-De-La-Torre, Leticia; Teodoro-Marin, Silvia; Rodríguez, Mónica; Domínguez-García, Olga; Rellan, Sara; Manso, Begoña; López-Abel, Bernardo; Álvarez-Pérez, Roser; Portillo-Marquez, Manuel; Rezola-Arcelus, Erika; Centeno-Malfaz, Fernando; Solana-Gracia, Ruth; Rojo-Sombrero, Henar; Cantero-Tejedor, María-Teresa; Riano, Bibiana; Tejero-Hernández, María-Ángeles; Jiménez-Casso, Marisol; Sabate-Rotes, Anna (ELSEVIER, 2025-11)
    BACKGROUND: Ascending aorta (AscAo) dilatation assessment and definition in pediatric bicuspid aortic valve (BAV) is challenging. We compared the Pediatric Heart Network (PHN) nomogram against the Halifax (HZ) one and ...
  • Enhancing diagnostic precision: a multicentric study of endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy in lymphoproliferative disorders 
    Ariza-Prota, Miguel; Perez-Pallares, Javier; Barisione, Emanuela; Cruz-Rueda, Juan Jose; Onyancha, Sammy; Usturoi, Daniela; De Santis, Michele; Salcedo-Lobera, Esperanza; Ferrer-Pargada, Diego; Corcione, Nadia; Caballero-Vazquez, Alberto; Rodriguez-Blanco, Ignacio; Torres-Rivas, Hector; Fernandez-Fernandez, Luis; Velasco-Albendea, Francisco Javier; Garcia-Clemente, Marta; Lopez-Gonzalez, Francisco (EUROPEAN RESPIRATORY SOC JOURNALS LTD, 2025-09)
    BACKGROUND: The diagnostic accuracy of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for the diagnosis of lymphoma has a low overall sensitivity. The lack of tissue architecture obtained by ...
  • Efficacy and safety of efavirenz in Niemann-Pick disease type C 
    Gascon-Bayarri, Jordi; Rico, Inmaculada; Sanchez-Castaneda, Cristina; Ledesma, Maria Dolores; Carnaval, Thiago; Bejr-Kasem, Helena; Campdelacreu, Jaume; Ferrer, Anna; Rodriguez-Bel, Laura; Cos, Monica; de Lama, Eugenia; de Munain, Adolfo Lopez; Rouco, Idoia; Perez-Sousa, Celia; Cerdan, Maria; Muelas, Nuria; Sevillano, Maria Dolores; Mir, Pablo; Villoria, Jesus; Videla, Sebastian (ELSEVIER SCIENCE INC, 2025-09)
    INTRODUCTION: In search of disease-modifying treatments for the Niemann-Pick disease type C (NPC), this Phase II single-arm clinical trial evaluated the safety and efficacy of efavirenz, a reverse transcriptase inhibitor ...
  • Impact of a community-based educational intervention on the burden and health-related quality of life of informal caregivers 
    Martínez-Melero, Inmaculada; Ruiz-García, María-Jesús; Ruiz-Merino, Guadalupe; García-Rubio, Ana (MOSBY-ELSEVIER, 2025-09)
    BACKGROUND: Caregiving for immobilized patients presents significant challenges that can profoundly impact the mental and physical health of informal caregivers. This study evaluates the impact of a community-based educational ...
  • Lower rate of pancreatobiliary complications after sludge and microlithiasis pancreatitis compared to gallstone pancreatitis 
    Sirtl, Simon; Teodorescu, Bianca; Gilberg, Leónard; Schafer, Arlett; Beyer, Georg; Arnau, Anna; López-Guillén, Pablo; Martínez-Domínguez, Samuel-J; Abad-Baroja, Daniel; Oyon, Daniel; Ruiz-Belmonte, Lara-M; Tejedor-Tejada, Javier; Zapater, Raúl; Martín-Vicente, Noelia; Fernández-Esparcia, Pedro-José; Julián-Gomara, Ana-Belén; Sastre-Lozano, Violeta-María; Manzanares-García, Juan-José; Chivato-Martín-Falquina, Irene; Andrés-Pascual, Laura; Torres-Monclús, Nuria; Zaragoza-Velasco, Natividad; Rojo, Eukene; Lapena-Muñoz, Berta; Flores, Virginia; Díaz-Gómez, Arantxa; Canamares-Orbis, Pablo; Vinzo-Abizanda, Isabel; Carrasco, Natalia-Marcos; Pardo-Grau, Laura; García-Rayado, Guillermo; Millastre-Bocos, Judith; García-García-de-Paredes, Ana; Vaamonde-Lorenzo, María; Izaguirre-Arostegi, Arantzazu; Lozada-Hernández, Edgard-Efren; Velarde-Ruiz-Velasco, José-Antonio; Zorniak, Michal; de-Madaria, Enrique; Mayerle, Julia; Velamazan, Raúl (ELSEVIER SCIENCE INC, 2025-09)
    BACKGROUND AND AIMS: Cholecystectomy is recommended to prevent recurrence of biliary pancreatitis, but supporting evidence is limited for sludge- and microlithiasis-induced acute pancreatitis (AP). This study aimed to ...
  • Moderate-to-severe hypercalcemia secondary to primary hyperparathyroidism refractory to conventional treatment (therapeutic management with denosumab): case report and literature review 
    Carpio-Salmerón, Manuel; Tebar-Caballero, Mariano; Marín-Martínez, Luis; Marco-Alacid, Cristian (AFRICAN FIELD EPIDEMIOLOGY NETWORK-AFENET, 2025)
    Severe hypercalcemia resistant to conventional medical treatment is a rare complication of primary hyperparathyroidism, and published information on the use of denosumab in patients with this condition is limited. This ...
  • Sotos Syndrome and Nephrocalcinosis a Rare But Possible Association Due to Impact on Contiguous Genes 
    González-Rodríguez, Juan-David; Inglés-Torres, Esther-Quiteria; Cabrera-Sevilla, José-Eugenio; Ibáñez-Mico, Salvador; Bermejo-Costa, Francisca; Vera-Carbonell, Ascensión; Bafalliu, Juan-Antonio; Cortes-Mora, Pedro-Andrés; Lorente-Nicolas, Ana; Donate-Legaz, José-María (GALENOS PUBL HOUSE, 2025-05-27)
    One-month old, breastfeeding infant, born at term, with normal anthropometric measurements at birth was referred to Pediatric Nephrology due to a nephrocalcinosis. The patient presented with dysmorphic features and heart ...
  • Impact of Endovascular Treatment on the Development of Post-Thrombotic Syndrome in Iliac and Iliofemoral Deep Vein Thrombosis 
    Puche-Palao, Gabriel; Trujillo-Santos, Javier; Otalora-Valderrama, Sonia; Guirado-Torrecillas, Leticia; Pagán-Escribano, Javier; Demelo-Rodríguez, Pablo (MDPI, 2025-09-05)
    Background: Post-thrombotic syndrome (PTS) is a frequent complication of deep vein thrombosis (DVT), with significant clinical and quality-of-life implications. Endovascular techniques have emerged as potential strategies ...
  • Clinical and Proteomic Insights into a Cytokine Release Syndrome Triggered by Tebentafusp in a Metastatic Uveal Melanoma Patient: Case Report 
    Lázaro-Sánchez, Antonio-David; Benítez-Fuentes, Javier-David; Luengo-Gil, Ginés; García-García, María-Teresa; Feliciangeli-Moreno, Eduardo; Conesa-Zamora, Pablo; Balsalobre-Yago, José; Mohamed-Mohamed, Kauzar; Arroyo-Rodríguez, Ana-Belén (MDPI, 2025-02-17)
    Background: Uveal melanoma is the most common primary intraocular cancer in adults; however, it remains rare. Despite its rarity, metastatic uveal melanoma poses significant treatment challenges. Tebentafusp, a T-cell ...
  • Systemic Immune and Tumor Marker Profiles in Ovarian and Deep Infiltrating Endometriosis: Associations with Disease Severity and Symptom Burden 
    Ramírez-Pávez, Tamara-Nadira; Marín-Sánchez, María-del-Pilar; Nebot-Navarro, Ana; García-Izquierdo, Laura; Nieto-Meca, Lucía; Sánchez, Rocío; Machado-Linde, Francisco; Martínez-Esparza, María (MDPI, 2025-10-01)
    Endometriosis is a chronic, estrogen-dependent inflammatory disease with heterogeneous clinical manifestations and uncertain systemic immune involvement. This study aimed to characterize peripheral immune profiles and ...
  • Docetaxel Resistance in Breast Cancer: Current Insights and Future Directions 
    Postigo-Corrales, Fátima; Beltran-Videla, Asunción; Lázaro-Sánchez, Antonio-David; Hurtado-López, Ana-María; Conesa-Zamora, Pablo; Arroyo-Rodríguez, Ana-Belén; Luengo-Gil, Ginés (MDPI, 2025-07-23)
    Docetaxel is a chemotherapeutic agent widely used for breast cancer treatment; however, its efficacy is often limited by drug resistance and associated toxicity. This review examines the molecular mechanisms of docetaxel ...
  • Expression of Fascin and DNA Topoisomerase 2-Alpha in Breast Carcinoma: Correlation with Histological Subtypes and Other Prognostic Markers 
    Sánchez-Espinosa, Alberto; García-Rodríguez, José; Alonso-Aguirre, Virginia; Acosta-Ortega, Jesús-María; Conesa-Zamora, Pablo; García-Solano, José; Luengo-Gil, Ginés (MDPI, 2025-03-27)
    BACKGROUND/OBJECTIVES: Breast cancer is the most prevalent cancer in adult women. Currently, new therapies and protein determinations with prognostic value are under development. Fascin (encoded by the FSCN1 gene) is an ...
  • Experiences of Sexuality in HIV Serodiscordant Gay Couples 
    Ruiz-Ramírez, María-Dolores; Ruiz-Fernández, María-Dolores; Ayala-Maqueda, María-del-Rosario; Camacho-Ávila, Marcos; Fernández-Medina, Isabel-María; Ventura-Miranda, María-Isabel (MDPI, 2025-07-23)
    Background/Objectives: Human immunodeficiency virus (HIV) has evolved from a fatal disease to a manageable chronic condition. However, stigma persists, affecting the lives and sexuality of HIV-positive people, particularly ...
  • Patient and Public Involvement in Malnutrition Disorders Health Research: A Methodological Systematic Review Protocol 
    García-García, Arturo; Carretero-Randez, Cristina; Camacho-Bejarano, Rafaela; Roldan-Chicano, María-Teresa; Castellano-Santana, Pedro-Raúl; Camacho-Montano, Lucía-Rocio; Montero-Marco, Jesica; Charlo-Bernardos, Marta; Orts-Cortes, María-Isabel (MDPI, 2025-04-07)
    Background/Objectives: Older adults are particularly susceptible to undernutrition and conditions that can aggravate it, such as frailty and conditions associated with swallowing difficulties or dysphagia. To address these ...
  • Resources and Readmission for COPD Exacerbation in Pneumology Units in Spain: The COPD Observatory Project 
    Calle-Rubio, Myriam; Cebollero-Rivas, Pilar; Esteban, Cristóbal; Fuster-Gomila, Antonia; García-Guerra, José-Alfonso; Golpe, Rafael; Hernández-Hernández, Jesús-R; Lozada-Bonilla, Jessica-Sara; Figueira-Goncalves, Juan-Marco; Marquez, Eduardo; Martínez-Garceran, José-Javier; de-Miguel-Diez, Javier; Pando-Sandoval, Ana; Riesco, Juan-A; Pérez, Salud-Santos; Sánchez-del-Hoyo, Rafael; Rodríguez-Hermosa, Juan-Luis (MDPI, 2025-02-04)
    Chronic obstructive pulmonary disease (COPD) represents one of the most frequent causes of hospital readmissions and in-hospital mortality. One in five patients requires readmission within 30 days of discharge following ...
  • Multicenter Real-World Study: 432 Patients with Apalutamide in Metastatic Hormone-Sensitive Prostate Cancer 
    Encarnación-Navarro, Juan-Antonio; Morillo-Macias, Virginia; Calbo, María-Borras; de-la-Fuente-Muñoz, Isabel; Lozano-Martínez, Antonio-José; García-Martínez, Vicente-Luis; Fernández-Fornos, Luis; Roche, Miriam-Guijarro; Rey, Osamah-Amr; García-Gómez, Raquel (MDPI, 2025-02-21)
    Background: The management of metastatic hormone-sensitive prostate cancer (mHSPC) has evolved significantly in recent years due to the introduction of androgen receptor-targeted agents (ARTAs). When used alongside androgen ...
  • Apalutamide and Stereotactic Body Radiotherapy in Metastatic Hormone-Sensitive Prostate Cancer: Multicenter Real-World Study 
    Encarnación-Navarro, Juan-Antonio; Morillo-Macias, Virginia; de-la-Fuente-Muñoz, Isabel; Derrac-Soria, Violeta; Fernández-Fornos, Luis; Antequera, María-Albert; Rey, Osamah-Amr; García-Martínez, Vicente; Alonso-Romero, José-Luis; García-Gómez, Raquel (MDPI, 2025-07-02)
    BACKGROUND: The management of metastatic hormone-sensitive prostate cancer (mHSPC) has evolved with the integration of androgen receptor signaling inhibitors (ARSIs) and metastasis-directed therapies (MDTs). Stereotactic ...
  • Real-World Use of COMT Inhibitors in the Management of Patients with Parkinson's Disease in Spain Who Present Early Motor Fluctuations: Interim Results from the REONPARK Study (vol 15, 532, 2025) 
    López-Manzanares, Lydia; García-Caldentey, Juan; Mata-Álvarez-Santullano, Marina; Vilas-Rolan, Dolores; Herreros-Rodríguez, Jaime; Solano-Vila, Berta; Cerdán-Sánchez, María; Delgado-Ballestero, Tania; García-Ramos, Rocío; Rodríguez-Sanz, Ana; Olivares-Romero, Jesús; Blanco-Ameijeiras, José; Pijuan-Jiménez, Isabel; Tegel-Ayuela, Iciar (MDPI, 2025-11-14)
    There was an error in the original publication [...].
  • Real-World Use of COMT Inhibitors in the Management of Patients with Parkinson's Disease in Spain Who Present Early Motor Fluctuations: Interim Results from the REONPARK Study 
    López-Manzanares, Lydia; García-Caldentey, Juan; Mata-Álvarez-Santullano, Marina; Vilas-Rolan, Dolores; Herreros-Rodríguez, Jaime; Solano-Vila, Berta; Cerdán-Sánchez, María; Delgado-Ballestero, Tania; García-Ramos, Rocío; Rodríguez-Sanz, Ana; Olivares-Romero, Jesús; Blanco-Ameijeiras, José; Pijuan-Jiménez, Isabel; Tegel-Ayuela, Iciar (MDPI, 2025-05-21)
    OBJECTIVE: We aimed to analyze the real-world use of COMT inhibitors associated with levodopa in patients with Parkinson's disease (PD) who present early fluctuations and to explore whether early COMT inhibition optimizes ...

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