• Construct Validity of Frontier Large Language Models on 4 Spanish Health Professions Specialty-Access Examinations (MIR, EIR, PIR, and FIR): Cross-Sectional Benchmarking and Psychometric Study. 

  García-Hidalgo, Clemente; Carpio-Salmerón, Manuel; Benito, Pau; Carazo-Casas, Carlos; Carratala, Beatriz; Campos-Pavon, Jaime (JMIR PUBLICATIONS INC., 2026-10-29)

  BACKGROUND: Large language models (LLMs) achieve high scores on health-professions examinations. Whether these scores support the same interpretations as human scores remains uncertain. Spain uses parallel multiple-choice ...
• Correlation Between Ultrasound-Derived Diaphragmatic Thickness, Inspiratory Muscle Strength and Peak Expiratory Flow in Institutionalized Older Adults: A Cross-Sectional Exploratory Study 

  de-Oliveira-Sousa, Silvana-Loana; Portillo-Castano, Felipe-J; Fernández-Azorin, Luis; Leon-Morillas, Felipe; Ríos-Cortés, Antonio-Tomás; Oliveira, Adriana-C-de-Souza (MDPI, 2026-10-21)

  Background: Diaphragm thickness may affect both inspiratory and expiratory function. The ultrasound assessment of diaphragm thickness could be a valuable tool for respiratory muscle evaluation in older adults, although ...
• Short-Term Methylcobalamin Supplementation Is Associated with Changes in Anaerobic and Cognitive Performance in Amateur Cyclists: A Randomized Crossover Trial 

  Martínez-Noguera, Francisco-Javier; Alcaraz, Pedro-E; González-Blanc, Francisco-Jesús; Huyghe, Thomas-G; Marín-Pagán, Cristian (MDPI AG, 2026-05-23)

  Introduction: Vitamin B12 (VB12), particularly its active form methylcobalamin (MeB12), contributes to neuromuscular function and energy metabolism, which may be relevant for sports performance. However, evidence on the ...
• Non-technique-related healthcare utilization and costs among dialysis and kidney transplant recipients in Spain: a real-world analysis 

  Santamaria, Rafael; Escobar, Carlos; Aranda, Unai; Palacios, Beatriz; Capel, Margarita; Hernández, Ignacio; Cebrián-Cuenca, Ana-María; Gorostidi, Manuel; Alcazar, Roberto (BMC, 2026-07-22)

  BACKGROUND: Kidney failure requiring kidney replacement therapy (KRT) is associated with a substantial and growing economic burden. While the costs directly attributable to KRT modalities are well documented, the resource ...
• A Randomized Controlled Pilot Trial Evaluating the Efficacy of Intravaginal and Extravaginal K-Laser Therapy as a Personalized Non-Hormonal Treatment for Genitourinary Syndrome of Menopause 

  Martín-Valero, Rocío; Ruiz-Moreno, Antonia-M; Gallardo-García, Pablo-J; Martínez-Colmena, María-Dolores; Muñoz-Pagán, Catalina; González-Rojas, Pedro; Ortega-Quiñonero, Paloma (MDPI AG, 2026-07-15)

  Background/Objectives: Genitourinary Syndrome of Menopause (GSM) negatively affects quality of life in postmenopausal women, causing sexual dysfunction, vaginal atrophy, and pelvic discomfort. Personalized medicine highlights ...
• Real-World Use of Opicapone in Management of Patients with Parkinson's Disease and Early Motor Fluctuations in Spain: 12-Month Interim Analysis of REONPARK Study 

  López-Manzanares, Lydia; Cerdán-Sánchez, María; Solano-Vila, Berta; Delgado-Ballestero, Tania; García-Ramos, Rocio; García-Caldentey, Juan; Rodríguez-Sanz, Ana; Olivares-Romero, Jesús; Gaston, Itziar; Carmona-Abellan, Mar; Mata-Álvarez-Santullano, Marina; Vázquez-Picon, Raquel; Rodríguez-de-Miguel, Marta; Tegel-Ayuela, Iciar; Magalhaes, Diogo; Holenz, Joerg (MDPI, 2026-09-11)

  Objective: To evaluate the sustained real-world effectiveness and safety of catechol-O-methyltransferase (COMT) inhibitors added to levodopa in patients with Parkinson's disease (PD) presenting early motor fluctuations. ...
• Mental Health Among Adults with Diabetes in Spain: A Population-Based Matched Study of Emotional Well-Being, Depressive Symptoms, and Psychiatric Medication Use 

  López-de-Andrés, Ana; Chivato-Martín-Falquina, Tomás; Jiménez-García, Rodrigo; Zamorano-Leon, José-J; Carabantes-Alarcon, David; Bodas-Pinedo, Andrés; Merida, Diana-María; Fuentes-Arroyo, Lucía; Jiménez-Sierra, Lucía (MDPI, 2026-08-24)

  Background/Objectives: The objectives of this study were to compare emotional well-being, depressive symptoms, and psychiatric medication use between adults with and without diabetes in Spain and to identify sex-specific ...
• Illustrative Bayesian Reanalysis of Published Micronucleus Frequencies: A Retrospective Methodological Comparison of Classical and Jeffreys-Rule Estimates in Selected Radioprotection Groups 

  Alcaraz, Miguel; Serna-Berna, Alfredo; Achel, Daniel-Gyingiri; García-Gamuz, José-Antonio; Mercado-Diaz, Ana; Olivares, Amparo (MDPI, 2026-08-28)

  Published cytokinesis-block micronucleus (CBMN) frequencies, normalised to 500 binucleated cells (MN/500 BC), were used to illustrate how the choice of statistical parametrisation affects background-subtracted radioprotection ...
• Intrapelvic Neck Screw Migration after Trochanteric Fixation Nail Advanced Fixation of a Trochanteric Femoral Fracture: A Case Report and Proposed Treatment Algorithm 

  Slaoui-Berezak, Nabil; Llorens-Fernández, Jesús; Crespo-Cánovas, Jorge; Carrasco, Carles-Marián; Ferrero-Manzanal, Francisco (INDIAN ORTHOPAEDIC RESEARCH GROUP, 2026)

  Introduction: Although rare, mechanical failure of fixation in trochanteric fractures can lead to significant morbidity, particularly when medial migration of the cephalic screw occurs, posing a serious risk of life-threatening ...
• Epidemiological characterization of biliary tract cancer in a real-world cohort of patients from the Spanish TTD-RETUD gastrointestinal registry 

  Mercade, T-Macarulla; Castet, F; Trujillo, A-Castillo; García, R-Vera; Vidal-Tocino, R; Martin, A-J-Munoz; Alfonso, P-García; Montes, A-Fernández; de-Mena, M-Lobo; Alonso, R-M-Rodríguez; Aranda, E; Ortega, M-Granja; Adeva, J; Sánchez, A-Modrego; Gallego, R-Álvarez; Galan, J-Martínez; García-García, Teresa; de-Mena, I-Ruiz; Izquierdo, S-Aguilar; Munoa, A-la-Casta (ELSEVIER, 2026-09)
• Differential Temporal Dynamics and Motor-Non-Motor Dissociation After Inhaled Levodopa in Parkinson's Disease: A Post Hoc Analysis of the INLEVO-LIFE PD Study 

  Santos-García, Diego; Cerdán-Sánchez, María; Yanez-Bana, Rosa; Cabo, Iria; Cimas-Hernando, María-Iciar (MDPI, 2026-10-17)

  BACKGROUND/OBJECTIVES: OFF episodes in Parkinson's disease (PD) include motor and non-motor manifestations, but their resolution after on-demand therapy may not be synchronous. We examined within-patient temporal dynamics ...
• The value of community engagement in the ESTRO-EORTC OligoCare project: A quantification of the in-kind contributions 

  Cusumano, Davide; Scaggion, Alessandro; Lievens, Yolande; Clementel, Enrico; Nuyens, Sarah; Alongi, Filippo; Benavente, Sergi; Braam, Petra; Dirix, Piet; Hemmatazad, Hossein; Jeene, Paul; Jereczek-Fossa, Barbara-Alicja; Greto, Daniela; Ramella, Sara; But-Hadzic, Jasna; Ricardi, Umberto; Salinas-Ramos, Juan; Scorsetti, Marta; Sirak, Igor; Stellamans, Karin; Widder, Joachim; Ost, Piet; Guckenberger, Matthias (ELSEVIER IRELAND LTD, 2027-01)
• Improvement in Quality of Life and Non-Motor Symptoms Associated With OFF Episodes in People With Parkinson's Disease Treated With Inhaled Levodopa 

  Santos-García, Diego; Cerdán-Sánchez, María; Yanez-Bana, Rosa; Cabo, Iria; Cimas-Hernando, María-Iciar (WILEY, 2026-08)

  BACKGROUND: CVT-301 (Inbrija) has demonstrated its effectiveness in treating OFF periods in people with Parkinson's disease (PwP). However, its effect on non-motor symptoms (NMS) and quality of life has not been researched ...
• CaReMe en atención primaria: estrategias integrales para el manejo del paciente cardio-renal-metabólico 

  Cabello, M-I-Egocheaga; Álvarez, P-Alonso; Moraga, M-J-Castillo; Cebrián-Cuenca, Ana-María; Sagarra, C-Cols; Drak, Y; Ramos, P-García; Rebollar, J-C-Obaya; Gil, F-Adan (ELSEVIER, 2026-11)

  The cardio-renal-metabolic (CaReMe) syndrome captures the interplay among metabolic factors, kidney damage, and cardiovascular disease, constituting a progressive and preventable process. This educational practical review ...
• Integrative microbiome-methylome analysis links bacterial taxa to colorectal cancer histological subtypes 

  Escudero-Jiménez, Angel; Galán-Ros, Jorge; Huertas-López, Francisco; Pérez-Sarabia, Andrea; Ribeiro, Diogo; Postigo-Corrales, Fátima; Albaladejo-González, Ana; Díaz-López, Maria Isabel; López-Abellán, María-Dolores; García-Rodríguez, Jose; Beltrán-Videla, María-Asunción; Arroyo-Rodríguez, Ana-Belén; Hurtado-López, Ana-María; Tapia-Abellán, Ana; Corral-San-Miguel, Rubén; Rodríguez-Braun, Edith; Feliciangeli-Moreno, Eduardo; Sánchez-Espinosa, Alberto; Conesa, Ana; Luengo-Gil, Ginés; Conesa-Zamora, Pablo (AMER SOC MICROBIOLOGY, 2026-09-22)

  Colorectal cancer (CRC) arises through distinct molecular and histological routes that may be shaped by interactions between the mucosa-associated microbiota and host epigenetic regulation. We analyzed paired tumor and ...
• Glycemic Patterns Assessed by Continuous Glucose Monitoring in People with Type 2 Diabetes Treated with Insulin Glargine 100 U/mL in Primary Care: The GPDetect Study 

  Bellido, Virginia; Cebrián-Cuenca, Ana-María; Morales, Cristobal; de-las-Hazas, Alberto-S; Soto-González, Alfonso; Morer-Linan, Carla; Borrachero-Guijarro, José-Miguel; Cuatrecases, Gabriel; García, Elena-L; López-Fernández, Judith; Lozano-García, Silvia; Bayon, Alvaro-M; Nino-Azcarate, Cristina-M; Laclaustra, Oscar; Fuentealba, Paulina (SPRINGER HEIDELBERG, 2026-09)

  INTRODUCTION: Hypoglycemia is a common complication in people with type 2 diabetes mellitus (T2DM) treated with basal insulin, yet its true prevalence in real-world primary care remains underexplored. This study used blinded ...
• Stability Study of a Frozen Oseltamivir 15 mg/mL Oral Solution in Amber Glass Bottles 

  Ruiz-Ramírez, Juan-Carlos; Gómiz-Sáez, Adrián; Martínez-Madrid, María-Encarnación; Viney, Alice-Charlotte; Alonso-Herreros, José-María; Almela-Rojo, Pilar (MDPI, 2026-09-08)
• Stability Study of Meropenem 50 mg/mL Eye Drops in Polypropylene Dropper Bottles 

  Ruiz-Ramírez, Juan-Carlos; Martínez-Madrid, María-Encarnación; Gómiz-Sáez, Adrián; Viney, Alice-Charlotte; Alonso-Herreros, José-María; Almela-Rojo, Pilar (MDPI, 2026-08-07)
• Fascin-Centred Invasive Competence in Eutopic Endometrium: A Hypothesis-Driven Narrative Review of Endometriosis Pathogenesis and Non-Surgical Biomarker Potential 

  Marín-Sánchez, María-del-Pilar; Ortega-Suárez, Daimaris; López-Soto, Álvaro; Kozak-Hensor, Irina; Benito-Villena, Rebeca; Vives-Ramírez, Marina; Postigo-Corrales, Fátima; Isaac-Montero, Alejandra; Conesa-Zamora, Pablo; Luengo-Gil, Ginés (MDPI, 2026-08-13)

  Endometriosis is a chronic, oestrogen-responsive inflammatory disease characterised by endometrial-like tissue outside the uterine cavity. Because retrograde menstruation is common, lesion establishment probably requires ...
• Nipple Melanoma: A Case Report and Review of the Literature 

  Ortiz-González, Ana; Torrent-García, Marina; Capozzi, Claudia-Alejandra; Ortiz-Reina, Sebastián; Balsalobre-Yago, José; Piñero-Madrona, Antonio; Cerezuela-Fuentes, Pablo (KARGER, 2026-08-14)

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