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Envíos recientes

02.02.01. Investigación y comunicación científica: Envíos recientes

  • Discovery of Z1362873773: a novel fascin inhibitor from a large chemical library for colorectal cancer 
    Rodríguez-Martínez, Alejandro; Giraldo-Ruiz, Lucía; Ramos, María-C; Luque, Irene; Ribeiro, Diogo; Postigo-Corrales, Fátima; Alburquerque-González, Begoña; Montoro-García, Silvia; Arroyo-Rodríguez, Ana-Belén; Conesa-Zamora, Pablo; Hurtado-López, Ana-María; Luengo-Gil, Ginés; Pérez-Sánchez, Horacio (NATURE PORTFOLIO, 2025-04-28)
    Metastasis is one of the leading causes of cancer-related death worldwide. Fascin, a protein that bundles actin filaments to produce protrusions in cancer cells, plays a significant role in the enhancement of cell migration. ...
  • A machine learning approach to identify patients at risk for long-term consequences after pulmonary embolism 
    Nopp, Stephan; Spielvogel, Clemens; Bikdeli, Behnood; Alberich-Conesa, Ana; Hernández-Blasco, Luis; Peris, Ma-Luisa; Otero, Remedios; Jiménez, David; Monreal, Manuel; Ay, Cihan; Agudo-de-Blas, P; Aibar, J; Alberich-Conesa, Ana; Alda-Lozano, A; Alfonso, J; Alonso-Carrillo, J; Álvarez-Vega, P; Amado, C; Angelina-García, M; Arcelus, J-I; Ballaz, A; Barba, R; Barbagelata, C; Barron, M; Barron-Andres, B; Bascuñana, J; Blanco-Molina, A; Bustos-Carpio, J; Casado, I; Chasco, L; Claver, G; De-Juana-Izquierdo, C; Del-Toro, J; Demelo-Rodríguez, P; Díaz-Brasero, A-M; Díaz-Pedroche, M-C; Díaz-Peromingo, J-A; Dubois-Silva, A; Escribano, J-C; Fernández-Capitan, C; Fernández-Jiménez, B; Fernández-Reyes, J-L; Fidalgo, M-A; Francisco, I; Gabara, C; Galeano-Valle, F; García-Bragado, F; García-González, C; García-Ortega, A; Gavin-Sebastian, O; Gil-de-Gómez, M-A; Gil-Díaz, A; Gómez-Cepeda, C; Gómez-Cuervo, C; González-Martínez, J; González-Munera, A; Gorostidi, J; Grau, E; Guirado-Torrecillas, Leticia; Gutiérrez-Guisado, J; Hernández-Blasco, L; Jara-Palomares, L; Jiménez, D; Jou, I; Joya, M-D; Lainez-Justo, S; Lecumberri, R; Lobo, J-L; López-Jiménez, L; López-Miguel, P; López-Núñez, J-J; López-Ruiz, Alfonso; López-Sáez, J-B; Lorenzo, A; Madridano, O; Maestre, A; Marchena, P-J; Marcos, M; Martín-del-Pozo, M; Martin-Martos, Francisco; Maza, J-M; Mercado, M-I; Molino, A; Monreal, M; Monzon, L; Navas, M-S; Nieto, J-A; Núñez-Fernández, M-J; Ordieres, L; Ortiz, O; Otalora-Valderrama, Sonia; Otero, R; Pacheco-Gómez, N; Pagan, J; Parra-Caballero, P; Pedrajas, J-M; Pérez-Amoros, J; Pérez-Cabezas, A; Pérez-Ductor, C; Pérez-Pinar, M; Peris, M-L; Pesce, M-L; Porras, J-A; Puchades, R; Puche, G; Rivas, A; Rivera-Civico, F; Rodríguez-Cobo, A; Romero-Bruguera, M; Salgueiro, G; Sánchez-Juez, A; Sancho, T; Sendin, V; Siguenza, P; Soler, S; Sota-Yoldi, L-A; Suárez-Fernández, S; Tirado, R; Torrents-Vilar, A; Torres, M-I; Trujillo-Santos, Javier; Uresandi, F; Valle, R; Varona, J-F; Vázquez, E; Villalobos, A; Villarejo, C; Villares, P; Ay, C; Nopp, S; Pabinger, I; Vanassche, T; Verhamme, P; Verstraete, A; Rocha, A-T; Yoo, H-H-B; Montenegro, A-C; Morales, S-N; Roa, J; Hirmerova, J; Maly, R; Acassat, S; Bertoletti, L; Brehon, M; Bura-Riviere, A; Catella, J; Chopard, R; Couturaud, F; Espitia, O; Le-Mao, R; Leclercq, B; Mahe, I; Moustafa, F; Plaisance, L; Poenou, G; Quere, I; Sarlon-Bartoli, G; Suchon, P; Versini, E; Schellong, S; Rashidi, F; Sadeghipour, P; Tahmasbi, F; Brenner, B; Kennet, G; Tzoran, I; Barillari, G; Basaglia, M; Bilora, F; Bissacco, D; Brandolin, B; Casana, R; Ciammaichella, M-M; Colaizzo, D; Di-Micco, P; Giorgi-Pierfranceschi, M; Grandone, E; Lambertenghi-Deliliers, D; Marcon, C; Poz, A; Prandoni, P; Simioni, P; Siniscalchi, C; Taflaj, B; Tufano, A; Visona, A; Zalunardo, B; Skride, A; Tazi-Mezalek, Z; Fonseca, S; Marques, R; Meireles, J; Pinto, S; Bosevski, M; Zdraveska, M; Barco, S; Bounameaux, H; Keller, S; Mazzolai, L; Porceddu, E; Aujayeb, A; Angiolillo, D-J; Bikdeli, B; Caprini, J-A; Khalil, A; Ortega-Paz, L; Tafur, J; Weinberg, I; Bui, H-M (NATURE PORTFOLIO, 2025-09-24)
    Pulmonary embolism (PE) can result in long-term sequelae, such as post-PE syndrome, including persistent dyspnea and chronic thromboembolic pulmonary hypertension (CTEPH). Existing prediction tools for severe post-PE ...
  • Impact of the initial administration of an antiretroviral drug with latency reversal properties on the HIV reservoir size 
    de-la-Torre-Tarazona, Erick; Moraga, Elisa; Vaquer, Raúl; Sánchez-Palomino, Sonsoles; de-Lazzari, Elisa; Luna, Laura; Vicens-Artes, Sonia; García-Fraile, Lucio-Jesús; Peraire, Joaquim; García-Gasalla, Mercedes; Balsalobre, Luz; Guillén-Martínez, Sergio; López-Cortés, Luis-Fernando; Jarrin, Inma; Serrano-Villar, Sergio; Alcami, José; Moreno, Santiago (NATURE PORTFOLIO, 2025-07-13)
    The elimination of the latent viral reservoir remains the main barrier in the quest for a cure for people with HIV (PWH). The administration of latency reversal agents (LRA) at antiretroviral treatment (ART) initiation ...
  • Clinical and immunopathological evaluation and its comparison with IHC consensus molecular subtypes of colorectal cancer 
    Feliciangeli-Moreno, Eduardo; Albaladejo-González, Ana; García-Rodríguez, José; Lázaro-Sánchez, Antonio-David; Borg, Rosanna; Pimentel-Cáceres, Paola; Soriano-Polo, Diego; Rodríguez-Braun, Edith; Balsalobre-Yago, José; Martínez-Ortiz, María-José; Wikstrom-Fernández, Sofía; Murillo-Herrera, Andrés; García-García, Teresa; García-Solano, José; Conesa-Zamora, Pablo; Luengo-Gil, Ginés (NATURE PORTFOLIO, 2025-07-01)
    This study examined the prognostic significance of immunoscore within consensus molecular subtypes (CMS), tumour budding (TB), and macrophage infiltration in colorectal cancer (CRC). A retrospective series was analysed ...
  • L.Fermentum CECT5716 and B.Breve CECT7263 on premature infants morbidities: a randomized clinical trial 
    Hurtado-Suazo, José-Antonio; Alonso-Ojembarrena, Almudena; Sánchez-Tamayo, Tomas; Martín-Álvarez, Estefanía; Sáez, María-Eugenia; Martínez-Pardo, Luz; Diez-Delgado-Rubio, Javier; Granero-Asencio, Mercedes; Serrano-López, Laura; Maldonado-Lobon, José-Antonio; Mora-Navarro, David; De-Benito-Guerra, María-Teresa; Torres-Begara, Eva; Ruiz-Moreno, Juan-Antonio; Macias-Díaz, Carmen; Lloreda-García, José-María; Peña-Caballero, Manuela; Olivares, Mónica; Blanco-Rojo, Ruth (SPRINGERNATURE, 2025-11-27)
    BACKGROUND: This study examined the effects of two doses of probiotics isolated from human milk on the incidences of necrotizing enterocolitis (NEC) and mortality in preterm infants. METHODS: This multicenter, randomized, ...
  • Rebuilding the atrophied brain: 6-month nasal esketamine therapy expands key frontal and hippocampal regions and reduces serum neurofilament levels in patients with major depressive disorder. A proof-of-concept study of the depTesk (DEPression treatment with ESKetamine) study 
    Rodríguez-Lorente, Ana; Campos-Navarro, María-Pilar; Gil-Montoya, Ángela; Marín-Pérez, Celia; Masó-Navarro, María-Luisa; Orgaz-Morales, Manuel-Tomás; López-Ramírez, Nuria; García-Carmona, Juan-Antonio (CAMBRIDGE UNIV PRESS, 2025)
    OBJECTIVES: This proof-of-concept study aimed to assess the impact of intranasal esketamine (ESK-IN) in brain volume and neurofilament light chain (sNfL) over 6-months in patients with treatment resistant depression (TDR). ...
  • 250 cases of "type 2 Gaucher disease": A novel system of clinical categorisation and evidence of genotype: Phenotype correlation 
    Donald, A; Brothwell, S; Cabello, B-M; Ehrstedt, C; Fernández-Fructuoso, Jose-Ramón; Fernández-Marin, E; González-Lamuno, D; Lloreda-García, José-María; Lykopoulou, L; Mignot, C; Nurse, J; O'Sullivan, S; Persson, A-N; Raiman, J; Rajan, D-S; Uberos, J; Jones, S-A; Church, H-J (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2025-06)
    'Type 2' Gaucher disease, also referred to as 'acute neuronopathic' or 'infantile' Gaucher disease is an aggressive subtype of Gaucher disease, resulting from pathogenic variants in GBA1. The spectrum of phenotype ranges ...
  • Consensus document for Severe Asthma. 2025 Update. 
    Álvarez-Gutierrez, Francisco-Javier; Blanco-Aparicio, Marina; Casas-Maldonado, Francisco; Plaza, Vicente; Soto-Campos, Gregorio; González-Barcala, Francisco-Javier; Almonacid, Carlos; Arismendi, Ebymar; Cabrera, Carlos; Cabestre-García, Roberto; Carretero, José-Ángel; Castilla-Martínez, Manuel; Castillo-Vizuete, José-Antonio; Cisneros-Serrano, Carolina; Gimeno-Díaz-de-Atauri, Álvaro; Díaz-Pérez, David; Domingo-Ribas, Christian; García-Rivero, Juan-Luis; López-Neyra, Alejandro; Martínez-Moragon, Eva; de-Mir-Messa, Inés; Muñoz-Gall, Xavier; Padilla-Galo, Alicia; Perpina-Tordera, Miguel; Pérez-de-Llano, Luis; Sánchez-Toril, Fernando; Sanz-Santiago, Veronica; Valverde-Molina, José (ELSEVIER, 2025-10)
    Severe asthma is a heterogeneous syndrome with several clinical variants and often represents a complex disease requiring a specialized and multidisciplinary approach, as well as the use of multiple drugs. The prevalence ...
  • Presentation and outcome in carriers of pathogenic variants in SLC34A1 and SLC34A3 encoding sodium-phosphate transporter NPT 2a and 2c 
    Brunkhorst, Max; Brunkhorst, Lena; Martens, Helge; Papizh, Svetlana; Besouw, Martine; Grasemann, Corinna; Turan, Serap; Sikora, Przemyslaw; Chromek, Milan; Cornelissen, Elisabeth; Fila, Marc; Lilien, Marc; Allgrove, Jeremy; Neuhaus, Thomas-J; Eltan, Mehmet; Espinosa, Laura; Schnabel, Dirk; Gokce, Ibrahim; González-Rodríguez, Juan-David; Khandelwal, Priyanka; Keijzer-Veen, Mandy-G; Lechner, Felix; Szcepanska, María; Zaniew, Marcin; Bacchetta, Justine; Emma, Francesco; Haffner, Dieter (ELSEVIER SCIENCE INC, 2025-01)
    Pathogenic variants in SLC34A1 and SLC34A3 encoding sodium-phosphate transporter 2a and 2c are rare causes of phosphate wasting. Since data on presentation and outcomes are scarce, we collected clinical, biochemical and ...
  • Effects of prior air pollution exposure on functional recovery after a myocardial infarction. 
    Baneras, Jordi; Berenguel-Senen, Alejandro; Pleguezuelos, Eulogio; Alarcón, José-Antonio; Vallejo, Jesús; Sanz-Ayan, Paz; Izquierdo-García, Juan; García, José; Colman, Rafael; Castillo-Martin, Juan-Ignacio; Rodenas-Alesina, Eduard (ELSEVIER, 2025-01)
    Air pollution is a major cardiovascular risk factor leading to higher rates of heart failure and myocardial infarction (MI), but its effects on functional recovery after an MI remain unknown. Cardiac rehabilitation is a ...
  • PET radiopharmaceuticals beyond 2-[18F]FDG for the evaluation of multiple myeloma and smoldering multiple myeloma 
    Travascio, Laura; Morales-Lozano, María-Isabel; Guglielmo, Priscilla; Cimini, Andrea; van-Essen, Martijn; Stavrou, Petros-Z; Vatsa, Rakhee; Grisanti, Fabiana (SPRINGER-VERLAG ITALIA SRL, 2025-07-19)
  • Cost-Utility Analysis of FreeStyle Libre Systems in People with Type 2 Diabetes Mellitus on Treatment with Basal Insulin and Poor Glycemic Control in Spain 
    Robles-Plaza, Mireya; Gómez-Peralta, Fernando; Bellido, Virginia; Ampudia-Blasco, Francisco-Javier; Carretero-Gómez, Juana; Cebrián-Cuenca, Ana-María; de-la-Cuadra-Grande, Alberto; Mezquita-Raya, Pedro (SPRINGER HEIDELBERG, 2026-01)
    INTRODUCTION: FreeStyle Libre (FSL) systems are effective and user-friendly glucose monitoring devices. This cost-effectiveness analysis compared FSL vs. self-blood glucose monitoring (SBGM) in patients with poorly controlled ...
  • A topical nociceutical formulation ameliorates chemotherapy-induced peripheral neuropathy: a pilot randomized clinical study 
    Servitja, Sonia; Castro-Henriques, María; Álvarez-Busto, Inaki; Diez-Franco, Carlota; Medina-Castillo, Alba; Algarra-García, María-Asunción; López-Miranda, Elena; Lario-Martínez, Margaret; Luengo-Alcázar, María-Isabel; Borregón-Rivilla, Miguel; Davo, Ana; Gasull-Delgado, Anna; Roque-García, Sara; Gonzaga-López, Ana; Poveda-Ferriols, Jesús-Manuel; Pascal, Severine; Mitroi-Marinescu, Ana-María; García-Escolano, Marta; Fernández-Carvajal, Asia; Ferrandiz-Huertas, Clotilde; Ferrer-Montiel, Antonio (SPRINGER INT PUBL AG, 2025-10-01)
    BACKGROUND: Up to 80% of patients undergoing taxanes or platinum-based chemotherapy (CT) develop a peripheral polyneuropathy (CIPN), that affects treatment compliance and quality of life (QoL). CIPN is characterized by a ...
  • Real-world management and outcomes of patients with hepatocellular carcinoma treated with systemic therapy in Spain: a patient cohort from the RETUD gastrointestinal registry 
    López-López, Carlos; Martínez-de-Castro, Eva; Fernández-Montes, Ana; Jiménez-Orozco, Encarnación; López-Peraita, Sandra; Vera, Ruth; Cerdá, Paula; Calvo, Mariona; García-Paredes, Beatriz; de-Mena, Miriam-Lobo; La-Casta, Adelaida; Gallego, Javier; Adeva, Jorge; Cano-Cano, Juana-M; Ruiz-Casado, Ana; Vidal-Tocino, Rosario; García-García, Teresa; Pazo-Cid, Roberto; Rodríguez-Garrote, Mercedes; Sastre, Javier (SPRINGER INT PUBL AG, 2025-08-09)
    PURPOSE: Characterization of the management and outcomes of patients diagnosed with hepatocellular carcinoma (HCC) and treated with systemic therapy who were included in the Spanish gastrointestinal RETUD registry. ...
  • Impact of HIV infection on the dynamics of liver stiffness in patients with hepatitis C virus chronic infection after sustained virological response 
    Martín-Carmona, Jesica; Corma-Gómez, Anais; Moyano, José-M; Tellez, Francisco; Arenga-Barrios, Dolores; Serrano-Fuentes, Miriam; Morano-Vázquez, Aitana-Carla; Corona-Mata, Diana; Navarrete-Lorite, Miguel-Nicolás; Vera-Méndez, Francisco-Jesús; Barroso, Isabel; Palacios, Rosario; de-los-Santos, Ignacio; Belinchon, Olga; Galera-Peñaranda, Carlos; Imaz, Arkaitz; Merino, Dolores; Reus-Banuls, Sergio-Javier; Galindo, María-José; López-Zuniga, Miguel-Ángel; Pineda, Juan-A; Macias, Juan (ELSEVIER, 2025-05)
    BACKGROUND: After sustained virological response (SVR), liver stiffness (LS) usually decreases. However, information related to the impact of HIV co-infection in patients with advanced fibrosis is scarce. The aim was to ...
  • Impact of Baseline Thrombocytopenia on Early Outcomes in Patients With Acute Venous Thromboembolism 
    Lecumberri, Ramón; Ruiz-Artacho, Pedro; Trujillo-Santos, Javier; Marcos-Jubilar, María; Pérez-Pinar, Montserrat; Quere, Isabelle; Claver, Gisela; Gorostidi, Juan; Bikdeli, Behnood; Monreal, Manuel; RIETE-Investigators (WILEY, 2025-03)
    Managing acute venous thromboembolism (VTE) in patients with thrombocytopenia is challenging. We used data from the RIETE registry to investigate the impact of baseline thrombocytopenia on early VTE-related outcomes, ...
  • Leishmaniasis in Patients With Inflammatory Bowel Disease: A National Multicenter Study of GETECCU 
    Madero-Velazquez, L; Mínguez, A; Mayorga, L; Ramírez, J-J; Moreno, N; Amoros, C; Nieto, M-A; Mena, R; Benítez, J-M; Gimeno-Pitarch, L; Maroto, N; Suria, C; Rodríguez-Moranta, F; Ordas, I; Ruiz, L; García-Brenes, M-A; Martín-Cardona, A; de-Celix, C-Rubin; Cardenas, K; Ginard, D; Medina, L; Pedrero-Leparmentier, Noemi; Plaza, R; Salmoral, R; Martínez-Pérez, T-J; Algara, V; Merino, E; Zabana, Y; Gutiérrez, A; Young-Group-GETECCU (WILEY, 2025-06)
    BACKGROUND: Leishmaniasis (LI) is a vector-borne illness caused by a protozoan of the genus Leishmania. Data on the features of LI in patients with inflammatory bowel disease (IBD) are scarce. AIM: To describe the ...
  • Stepped psychological intervention with common mental disorders in Primary Care 
    Martín-García-Sancho, Julio-César; Garriga-Puerto, Ascensión; Egea, Carmen; Díaz, Gonzalo; Campillo-Cascales, María-Josefa; Espínosa-Gil, Rosa-María (UNIV MURCIA, 2018-01)
  • Culture-bound syndromes in migratory contexts: the case of Bolivian immigrants 
    Roldán-Chicano, María-Teresa; Fernández-Rufete, Jose; Hueso-Montoro, César; del-Mar-García-López, María; Rodríguez-Tello, Javier; Dolores-Flores-Bienert, María (UNIV SAO PAULO, ESCOLA DE ENFERMAGEM DE RIBEIRAO PRETO, 2017)
    OBJECTIVE: to describe the culture-bound syndromes maintained by Bolivian immigrants in the new migratory context and analyze the care processes of these health problems. METHOD: qualitative research with an ethnographic ...
  • Raltegravir plus abacavir/lamivudine in virologically suppressed HIV-1-infected patients: 48-week results of the KIRAL study 
    Troya, Jesús; Montejano, Rocío; Ryan, Pablo; Gómez, Cristina; Matarranz, Mariano; Cabello, Alfonso; Vera, Francisco; Sepúlveda, María-Antonia; Santos, Ignacio; Samperiz, Gloria; Bachiller, Pablo; Boix, Vicente; Barrufet, Pilar; Cervero, Miguel; Sanz, Jose; Solis, Javier; Yllescas, María; Valencia, Eulalia (PUBLIC LIBRARY SCIENCE, 2018-06-14)
    BACKGROUND: Long-term combination antiretroviral therapy often results in toxicity/tolerability problems, which are one of the main reasons for switching treatment. Despite the favorable profile of raltegravir (RAL), data ...

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