Repositorio Dspace

Envíos recientes

03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla): Envíos recientes

  • Facial thermal variations: A new marker of emotional arousal 
    Kosonogov, Vladimir; de-Zorzi, Lucas; Honore, Jacques; Martínez-Velazquez, Eduardo-S; Nandrino, Jean-Louis; Martínez-Selva, José-M; Sequeira, Henrique (PUBLIC LIBRARY SCIENCE, 2017-09-18)
    Functional infrared thermal imaging (fITI) is considered a promising method to measure emotional autonomic responses through facial cutaneous thermal variations. However, the facial thermal response to emotions still needs ...
  • Post-Traumatic Stress Disorder and other mental disorders in the general population after Lorca's earthquakes, 2011 (Murcia, Spain): A cross-sectional study 
    Navarro-Mateu, Fernando; Salmerón-Martínez, Diego; Vilagut, Gemma; Tormo, María-José; Ruiz-Merino, Guadaiupe; Escamez, Teresa; Júdez, Javier; Martínez, Salvador; Koenen, Karestan-C; Navarro, Carmen; Alonso, Jordi; Kessler, Ronald-C (PUBLIC LIBRARY SCIENCE, 2017-07-19)
    AIMS: To describe the prevalence and severity of mental disorders and to examine differences in risk among those with and without a lifetime history prior to a moderate magnitude earthquake that took place in Lorca (Murcia, ...
  • Easy and non-invasive disease detection in pigs by adenosine deaminase activity determinations in saliva 
    Gutiérrez, Ana-María; de-la-Cruz-Sánchez, Ernesto; Montes, Ana; Sotillo, Juan; Gutiérrez-Panizo, Candido; Fuentes, Pablo; Tornel, Pedro-Luis; Cabezas-Herrera, Juan (PUBLIC LIBRARY SCIENCE, 2017-06-08)
    The quantification of adenosine deaminase (ADA) in porcine saliva samples has been analyzed for its use as a marker of disease. First, an analytical validation of the enzymatic assay used for ADA measurements was performed. ...
  • A new device for deep cervical artificial insemination in gilts reduces the number of sperm per dose without impairing final reproductive performance 
    Llamas-López, Pedro-J; López-Ubeda, Rebeca; López, Gustavo; Antinoja, Emily; García-Vázquez, Francisco-A (BMC, 2019-01-28)
    BACKGROUND: The aim of this study was to evaluate the reproductive performance of a new artificial insemination (AI) device specifically designed for gilts (Deep cervical AI, Dp-CAI) by means of which the sperm is deposited ...
  • The association of telomere length with substance use disorders: systematic review and meta-analysis protocol 
    Navarro-Mateu, Fernando; Rubio-Aparicio, María; Cayuela, Pedro; Álvarez, Francisco-Javier; Roca-Vega, Agustín; Chirlaque-López, María-Dolores; Cayuela-Fuentes, María-Luisa; Husky, Mathilde; Martínez, Salvador; Sánchez-Meca, Julio (BMC, 2019-12-01)
    BACKGROUND: The present protocol was designed for a systematic review and meta-analysis aimed at determining the association of telomere length with substance use disorders with the exclusion of nicotine addiction, and to ...
  • Silk fibroin scaffolds seeded with Wharton's jelly mesenchymal stem cells enhance re-epithelialization and reduce formation of scar tissue after cutaneous wound healing 
    Millan-Rivero, José-E; Martínez, Carlos-M; Romecin, Paola-A; Aznar-Cervantes, Salvador; Carpes-Ruiz, Marina; Cenis, José-L; Moraleda-Jiménez, José-María; Atucha, Noemi-M; García-Bernal, David (BMC, 2019-04-27)
    BACKGROUND: The treatment of extensive and/or chronic skin wounds is a widespread and costly public health problem. Mesenchymal stem cells (MSCs) have been proposed as a potential cell therapy for inducing wound healing ...
  • Risk prediction for estrogen receptor-specific breast cancers in two large prospective cohorts 
    Li, Kuanrong; Anderson, Garnet; Viallon, Vivian; Arveux, Patrick; Kvaskoff, Marina; Fournier, Agnes; Krogh, Vittorio; Tumino, Rosario; Sánchez, Maria-Jose; Ardanaz, Eva; Chirlaque-López, María-Dolores; Agudo, Antonio; Muller, David-C; Smith, Todd; Tzoulaki, Ioanna; Key, Timothy-J; Bueno-de-Mesquita, Bas; Trichopoulou, Antonia; Bamia, Christina; Orfanos, Philippos; Kaaks, Rudolf; Huesing, Anika; Fortner, Renee-T; Zeleniuch-Jacquotte, Anne; Sund, Malin; Dahm, Christina-C; Overvad, Kim; Aune, Dagfinn; Weiderpass, Elisabete; Romieu, Isabelle; Riboli, Elio; Gunter, Marc; Dossus, Laure; Prentice, Ross; Ferrari, Pietro (BMC, 2018-12-03)
    BACKGROUND: Few published breast cancer (BC) risk prediction models consider the heterogeneity of predictor variables between estrogen-receptor positive (ER+) and negative (ER-) tumors. Using data from two large cohorts, ...
  • Development and validation of circulating CA125 prediction models in postmenopausal women 
    Sasamoto, Naoko; Babic, Ana; Rosner, Bernard-A; Fortner, Renee-T; Vitonis, Allison-F; Yamamoto, Hidemi; Fichorova, Raina-N; Titus, Linda-J; Tjonneland, Anne; Hansen, Louise; Kvaskoff, Marina; Fournier, Agnes; Mancini, Francesca-Romana; Boeing, Heiner; Trichopoulou, Antonia; Peppa, Eleni; Karakatsani, Anna; Palli, Domenico; Grioni, Sara; Mattiello, Amalia; Tumino, Rosario; Fiano, Valentina; Onland-Moret, N-Charlotte; Weiderpass, Elisabete; Gram, Inger-T; Quirós, J-Ramón; Lujan-Barroso, Leila; Sánchez, Maria-Jose; Colorado-Yohar, Sandra; Barricarte-Gurrea, Aurelio; Amiano, Pilar; Idahl, Annika; Lundin, Eva; Sartor, Hanna; Khaw, Kay-Tee; Key, Timothy-J; Muller, David; Riboli, Elio; Gunter, Marc; Dossus, Laure; Trabert, Britton; Wentzensen, Nicolás; Kaaks, Rudolf; Cramer, Daniel-W; Tworoger, Shelley-S; Terry, Kathryn-L (BMC, 2019-11-26)
    BACKGROUND: Cancer Antigen 125 (CA125) is currently the best available ovarian cancer screening biomarker. However, CA125 has been limited by low sensitivity and specificity in part due to normal variation between individuals. ...
  • Microglial dynamics after axotomy-induced retinal ganglion cell death 
    Nadal-Nicolás, Francisco-M; Jiménez-López, Manuel; Salinas-Navarro, Manuel; Sobrado-Calvo, Paloma; Vidal-Sanz, Manuel; Agudo-Barriuso, Marta (BMC, 2017-11-09)
    BACKGROUND: Microglial cells (MCs) are the sentries of the central nervous system. In health, they are known as surveying MCs because they examine the tissue to maintain the homeostasis. In disease, they activate and, among ...
  • Adherence to the World Cancer Research Fund/American Institute for Cancer Research cancer prevention recommendations and risk of in situ breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort 
    Karavasiloglou, Nena; Huesing, Anika; Masala, Giovanna; van-Gils, Carla-H; Turzanski-Fortner, Renee; Chang-Claude, Jenny; Huybrechts, Inge; Weiderpass, Elisabete; Gunter, Marc; Arveux, Patrick; Fournier, Agnes; Kvaskoff, Marina; Tjonneland, Anne; Kyro, Cecilie; Dahm, Christina-C; Vistisen, Helene-Tilma; Bakker, Marije-F; Sánchez, Maria-Jose; Chirlaque-López, María-Dolores; Santiuste-de-Pablos, Carmen; Ardanaz, Eva; Menéndez, Virginia; Agudo, Antonio; Trichopoulou, Antonia; Karakatsani, Anna; La-Vecchia, Carlo; Peppa, Eleni; Palli, Domenico; Agnoli, Claudia; Panico, Salvatore; Tumino, Rosario; Sacerdote, Carlotta; Butt, Salma-Tuna; Borgquist, Signe; Skeie, Guri; Schulze, Matthias; Key, Timothy-J; Khaw, Kay-Tee; Tsilidis, Konstantinos-K; Ellingjord-Dale, Merete; Riboli, Elio; Kaaks, Rudolf; Dossus, Laure; Rohrmann, Sabine; Kuehn, Tilman (BMC, 2019-12-02)
    BACKGROUND: Even though in situ breast cancer (BCIS) accounts for a large proportion of the breast cancers diagnosed, few studies have investigated potential risk factors for BCIS. Their results suggest that some established ...
  • Tall height and obesity are associated with an increased risk of aggressive prostate cancer: results from the EPIC cohort study 
    Pérez-Cornago, Aurora; Appleby, Paul-N; Pischon, Tobias; Tsilidis, Konstantinos-K; Tjonneland, Anne; Olsen, Anja; Overvad, Kim; Kaaks, Rudolf; Kuehn, Tilman; Boeing, Heiner; Steffen, Annika; Trichopoulou, Antonia; Lagiou, Pagona; Kritikou, María; Krogh, Vittorio; Palli, Domenico; Sacerdote, Carlotta; Tumino, Rosario; Bueno-de-Mesquita, Bas; Agudo, Antonio; Larrañaga, Nerea; Molina-Portillo, Elena; Barricarte-Gurrea, Aurelio; Chirlaque-López, María-Dolores; Quirós, J-Ramón; Stattin, Par; Haggstrom, Christel; Wareham, Nick; Khaw, Kay-Tee; Schmidt, Julie-A; Gunter, Marc; Freisling, Heinz; Aune, Dagfinn; Ward, Heather; Riboli, Elio; Key, Timothy-J; Travis, Ruth-C (BMC, 2017-07-13)
    BACKGROUND: The relationship between body size and prostate cancer risk, and in particular risk by tumour characteristics, is not clear because most studies have not differentiated between high-grade or advanced stage ...
  • Applying trans-theoretical model for blood donation among Spanish adults: a cross-sectional study 
    Sardi, Lamyae; Idri, Ali; Carrillo-de-Gea, Juan-Manuel; Toval, Ángel; Fernández-Aleman, José-Luis (BMC, 2019-12-23)
    BACKGROUND: Relying solely on altruistic appeals may fail to fulfil the increasing demand for blood supplies. Current research has largely been attempted to determine and understand motives that serve as blood donation ...
  • Receptor activator of nuclear factor kB ligand, osteoprotegerin, and risk of death following a breast cancer diagnosis: results from the EPIC cohort 
    Sarink, Danja; Schock, Helena; Johnson, Theron; Chang-Claude, Jenny; Overvad, Kim; Olsen, Anja; Tjonneland, Anne; Arveux, Patrick; Fournier, Agnes; Kvaskoff, Marina; Boeing, Heiner; Karakatsani, Anna; Trichopoulou, Antonia; La-Vecchia, Carlo; Masala, Giovanna; Agnoli, Claudia; Panico, Salvatore; Tumino, Rosario; Sacerdote, Carlotta; van-Gils, Carla-H; Peeters, Petra-H-M; Weiderpass, Elisabete; Agudo, Antonio; Rodríguez-Barranco, Miguel; Huerta-Castaño, José-María; Ardanaz, Eva; Gil, Leire; Kaw, Kay-Tee; Schmidt, Julie-A; Dossus, Laure; His, Mathilde; Aune, Dagfinn; Riboli, Elio; Kaaks, Rudolf; Fortner, Renee-T (BMC, 2018-10-22)
    BACKGROUND: Receptor activator of nuclear factor kappa-B (RANK)-signaling is involved in tumor growth and spread in experimental models. Binding of RANK ligand (RANKL) to RANK activates signaling, which is inhibited by ...
  • Rag1 immunodeficiency-induced early aging and senescence in zebrafish are dependent on chronic inflammation and oxidative stress 
    Novoa, Beatriz; Pereiro, Patricia; López-Muñoz, Azucena; Varela, Mónica; Forn-Cuni, Gabriel; Anchelin, Monique; Dios, Sonia; Romero, Alejandro; Martínez-López, Alicia; Medina-Gali, Regla-María; Collado, Manuel; Coll, Julio; Estepa, Amparo; Cayuela-Fuentes, María-Luisa; Mulero, Víctoriano; Figueras, Antonio (WILEY, 2019-10)
    In mammals, recombination activating gene 1 (RAG1) plays a crucial role in adaptive immunity, generating a vast range of immunoglobulins. Rag1(-/-) zebrafish (Danio rerio) are viable and reach adulthood without obvious ...
  • Trehalose: is it a potential inhibitor of antithrombin polymerization? 
    Martínez-Martínez, Irene (PORTLAND PRESS LTD, 2019-06-18)
    SERine Protease INhibitorS (Serpins) are a superfamily of proteins that are characterized by having a similar three-dimensional structure. The native conformation is not most thermodynamically stable, so polymerization is ...
  • A new cross-linked enzyme aggregate biocatalyst for NAD+-booster production 
    Martínez-Monino, Ana-Belén; Zapata-Pérez, Rubén; García-Saura, Antonio-Gines; Cabanes, Juana; Sánchez-Ferrer, Álvaro (ROYAL SOC CHEMISTRY, 2017)
  • Somatostatin receptor-targeted organometallic iridium(III) complexes as novel theranostic agents 
    Novohradsky, Vojtech; Zamora, Ana; Gandioso, Albert; Brabec, Viktor; Ruiz, José; Marchan, Vicente (ROYAL SOC CHEMISTRY, 2017-05-18)
    A novel somatostatin receptor-targeted anticancer agent based on the conjugation of a highly cytotoxic and luminescent cyclometalated iridium(iii) complex to tumor-targeting vectors based on octreotide peptide has been ...
  • Transient desialylation in combination with a novel antithrombin deficiency causing a severe and recurrent thrombosis despite anticoagulation therapy 
    Revilla, Nuria; de-la-Morena-Barrio, María-Eugenia; Minano, Antonia; López-Gálvez, Raquel; Toderici, Mara; Padilla, José; García-Avello, Ángel; Lozano-Almela, María-Luisa; Lefeber, Dirk-J; Corral, Javier; Vicente, Vicente (NATURE PORTFOLIO, 2017-03-17)
    An in-depth focused study of specific cases of patients with recurrent thrombosis may help to identify novel circumstances, genetic and acquired factors contributing to the development of this disorder. The aim of this ...
  • PARP-1/PARP-2 double deficiency in mouse T cells results in faulty immune responses and T lymphomas 
    Navarro, Judith; Gozalbo-López, Beatriz; Mendez, Andrea-C; Dantzer, Francoise; Schreiber, Valerie; Martínez, Carlos; Arana, David-M; Farres, Jordi; Revilla-Nuin, Beatriz; Bueno, María-F; Ampurdanes, Coral; Galindo-Campos, Miguel-A; Knobel, Philip-A; Segura-Bayona, Sandra; Martín-Caballero, Juan; Stracker, Travis-H; Aparicio, Pedro; del-Val, Margarita; Yelamos, José (NATURE PORTFOLIO, 2017-02-09)
    The maintenance of T-cell homeostasis must be tightly regulated. Here, we have identified a coordinated role of Poly(ADP-ribose) polymerase-1 (PARP-1) and PARP-2 in maintaining T-lymphocyte number and function. Mice bearing ...
  • Deciphering predictive factors for choice of thrombopoietin receptor agonist, treatment free responses, and thrombotic events in immune thrombocytopenia 
    Lozano, María-Luisa; Mingot-Castellano, María-E; Perera, María-M; Jarque, Isidro; Campos-Álvarez, Rosa-M; González-López, Tomas-J; Carreno-Tarragona, Gonzalo; Bermejo, Nuria; López-Fernández, María-F; de-Andrés, Aurora; Valcarcel, David; Casado-Montero, Luis-F; Álvarez-Roman, María-T; Orts, María-I; Novelli, Silvana; Revilla, Nuria; González-Porras, José-R; Bolanos, Estefania; Rodríguez-López, Manuel-A; Orna-Montero, Elisa; Vicente, Vicente (NATURE PORTFOLIO, 2019-11-13)
    Very few data exist on when a particular thrombopoietin-receptor agonist (TPO-RA) is favored in clinical practice for the treatment of patients with immune thrombocytopenia (ITP), about novel risk factors for vascular ...

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