• Marked increase in cryptosporidiosis cases, Spain, 2023 

  Peñuelas-Martínez, Marina; Carmena, David; Guzmán-Herrador, Bernardo-R; Palau-Miguel, Margarita; Saravia-Campelli, Gabriela; García-Álvarez, Rosa-María; Guerrero-Vadillo, Mariá; Dashti, Alejandro; Köster, Pamela-C; Guevara-Alemany, Esperanza; Simón-Soria, (EUR CENTRE DIS PREVENTION & CONTROL, 10.2807156)

  BackgroundBy mid-September 2023, several event notifications related to cryptosporidiosis had been identified from different regions in Spain. Therefore, a request for urgent notification of cryptosporidiosis cases to the ...
• Implication of Hepsin from Primary Tumor in the Prognosis of Colorectal Cancer Patients 

  Zaragoza-Huesca, David; Nieto-Olivares, Andres; Garcia-Molina, Francisco; Ricote, Guillermo; Montenegro, Sofia; Sánchez-Canovas, Manuel; Garrido-Rodríguez, Pedro; Penas-Martínez, Julia; Vicente, Vicente; Martínez, Francisco; Lozano, Maria-Luisa; Carmona-B (MDPI, 10.3390can)

  Hepsin is a type II transmembrane serine protease whose deregulation promotes tumor invasion by proteolysis of the pericellular components. In colorectal cancer, the implication of hepsin is unknown. Consequently, we aimed ...
• Acute Effects of Surgical and FFP2 Face Masks on Physiological Responses and Strength Performance in Persons with Sarcopenia 

  Ramos-Campo, Domingo-Jesus; Pérez-Pinero, Silvia; Muñoz-Carrillo, Juan-Carlos; López-Roman, Francisco-Javier; Garcia-Sánchez, Esther; Avila-Gandia, Vicente (MDPI, 10.3390bio)

  Due to COVID-19, wearing a face mask to reduce virus transmission is currently mandatory in some countries when participants practice exercise in sports centers. Therefore, the aim of the present study was to analyze the ...
• Global overview of the management of acute cholecystitis during the COVID-19 pandemic (CHOLECOVID study) 

  Spiers, Harry-V-M; Kouli, Omar; Ahmed, Waheed-U; Varley, Rebecca; Argus, Leah; McLean, Kenneth-A; Kamarajah, Sivesh-K; Coe, Peter; Griffiths, E; Chan, Anthony-KC; Macutkiewicz, Christian; Jamdar, Saurabh; Wilson, Michael; Toogood, Giles; Siriwardena, Ajit (OXFORD UNIV PRESS, 10.1093bjs)

  Background: This study provides a global overview of the management of patients with acute cholecystitis during the initial phase of the COVID-19 pandemic. Methods: CHOLECOVID is an international, multicentre, observational ...
• Novel Homozygous Inactivating Mutation in the PCSK1 Gene in an Infant with Congenital Malabsorptive Diarrhea 

  Aerts, Laetitia; Terry, Nathalie-A; Sainath, Nina-N; Torres, Clarivet; Martin, Martin-G; Ramos-Molina, Bruno; Creemers, John-W (MDPI, 10.3390gen)

  Proprotein convertase 1/3 (PC1/3), encoded by the PCSK1 gene, is expressed in neuronal and (entero)endocrine cell types, where it cleaves and hence activates a number of protein precursors that play a key role in energy ...
• Gas mixture in noninvasive ventilation 

  Elshazly, Mostafa; Giancario, Garuti; Bayrakci, Benan; Sandoval, José-Luis; Ahmed, Hebatallah-Hesham; Esquinas-Rodríguez, Antonio (WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2026-03)

  Noninvasive ventilation (NIV) and high-flow nasal cannula are increasingly used to treat acute respiratory failure. Because many of these patients could also benefit from inhaled medications, combining aerosol therapy with ...
• Mid-Term Changes in Quality of Life and Nutritional Habits Following Gastric Bypass: A 24-Month Follow-Up Study 

  Martínez-Sánchez, María-Antonia; Ros-Madrid, Inmaculada; Fernández-Ruiz, Virginia-Esperanza; Cano-Mármol, Rosario-Paloma; Hernández-Morante, Juan-José; Núñez-Sánchez, María-Ángeles; Balaguer-Román, Andrés; Frutos-Bernal, María-Dolores; Ruiz-Alcaraz, Antonio-José; Queipo-Ortuño, María-Isabel; Ferrer-Gómez, Mercedes; Ramos-Molina, Bruno (MDPI, 2026-01-16)

  Background/Objectives: Obesity is an increasingly concerning public health issue due to its high prevalence and its association with multiple comorbidities. A significant proportion of patients with obesity who undergo ...
• Comprehensive Landscape of Diagnostic, Prognostic and Predictive Biomarkers in Colorectal Cancer: From Genomics to Multi-Omics Integration in Precision Medicine. 

  Agüera-Sánchez, Alfonso; Peña-Ros, Emilio; Martínez-Martínez, Irene; García-Molina, Francisco (MDPI, 2026-01-12)

  Colorectal cancer (CRC) remains one of the leading causes of cancer-related morbidity and mortality worldwide. Despite advances in screening and therapeutic strategies, early detection and individualized treatment remain ...
• The Impact of Ursodeoxycholic Acid on Maternal Cardiac Function in Women with Gestational Diabetes Mellitus: A Randomized Controlled Study (GUARDS Trial) 

  Company-Calabuig, Ana-María; Blanco-Carnero, José-Eliseo; Chatzakis, Christos; Williamson, Catherine; Nicolaides, Kypros-H; de-Paco-Matallana, Catalina; Charakida, Marietta (MDPI, 2026-01-19)

  Background: Gestational diabetes mellitus (GDM) is associated with metabolic disturbance and subclinical cardiovascular changes during pregnancy and after birth. Optimal glycaemic control remains challenging for many ...
• Systemic Inflammation Aggravates Retinal Ganglion Cell Vulnerability to Optic Nerve Trauma in Adult Rats. 

  Rovere, Giuseppe; Caja-Matas, Yolanda; Vidal-Villegas, Beatriz; Bernal-Garro, José-Manuel; Sobrado-Calvo, Paloma; Salinas-Navarro, Manuel; Nucci, Carlo; Villegas-Pérez, María-Paz; Vidal-Sanz, Manuel; Agudo-Barriuso, Marta; Nadal-Nicolás, Francisco-M (MDPI, 2026-02-03)

  Systemic inflammation is increasingly recognized as a modifier of neurodegenerative outcomes in the central nervous system; however, its impact on retinal ganglion cell (RGC) survival and retinal microglial responses ...
• Cervical Magnetic Resonance Imaging Profiles and Their Association with Cervical Pain in Dentists: A Cluster Analysis Study 

  López-Morales, Ana; Baño-Alcaraz, Aitor; López-Nicolás, Manuel; García-Vidal, José-Antonio; Cánovas-Ambit, Germán (MDPI, 2026-01-09)

  Background/Objectives: Neck pain is highly prevalent among dentists and has been linked to occupational exposure and cervical degeneration. However, the relationship between cervical MRI findings and symptoms remains ...
• Symptomatic Pheochromocytoma: A Risk Model. 

  Muñoz, María-Consuelo; Febrero, Beatriz; Abellán, Miriam; Rodríguez, José-Manuel (MDPI, 2026-02-06)

  Background/Objectives: Pheochromocytoma (PHEO) is increasingly detected incidentally or through genetic screening; however, predictors of symptomatic presentation and its perioperative impact remain unclear. We aimed to ...
• Field Homology in the Brain of Vertebrates. 

  Puelles, Luis; García-Calero, Elena (MDPI, 2026-01-29)

  In this commentary, we discuss the concept of field homology, particularly as applied to the brain in comparative neuromorphology. We emphasize its roots in the topological properties of the Bauplan notion (organization ...
• Exposure of in vitro maturing pig oocytes to exogenous interleukin-6 is associated with transcriptomic differences in the resulting blastocysts, with enrichment of developmental signaling pathways 

  García-Cánovas, Manuela; López-Jara, Adelina; Parrilla, Inmaculada; González-Plaza, Alejandro; Rodríguez-Martínez, Heriberto; Gil, María-Antonia; Cuello, Cristina; Martínez, Emilio-A (FRONTIERS MEDIA SA, 2026-01-05)

  Introduction: Interleukin-6 (IL-6) has recently emerged as a promising supplement for in vitro maturation (IVM), enhancing pig blastocyst development and reducing apoptosis following in vitro fertilization (IVF). This study ...
• Impact of the COVID-19 Pandemic on the Outcomes of a Multifaceted Program on Antibiotic Prescribing in Primary Care Among Children Under Three Years of Age 

  Martín-Ayala, Gema; Alfayate-Miguélez, Santiago; Jiménez-Guillén, Casimiro; AlcarazQuiñonero, Manuel; Iofrio-de-Arce, Antonio; Arnau-Sánchez, José (MDPI, 2026-01-19)

  Background/objective: Inappropriate antibiotic use in paediatric populations is a leading driver of antimicrobial resistance. In the Murcia Region, Spain, the Purapi program promotes the rational use of antibiotics among ...
• Dual role of ACE2 in regulating inflammation triggered by Omicron S1 and other SARS-CoV-2 Spike variants 

  Pedoto, AnnaMaría; Lozano-Gil, Juan-Manuel; Ocaña-Esparza, María; Conesa-Hernández, Ana-María; Candel, Sergio; Cayuela-Fuentes, María-Luisa; Mulero, Victoriano; Tyrkalska, Sylwia-D (FRONTIERS MEDIA SA, 2026-01-06)

  Since the emergence of SARS-CoV-2 in late 2019, substantial efforts have been made to understand its mechanisms of pathogenicity. Although angiotensin-converting enzyme 2 (ACE2) has been identified as the main receptor for ...
• De novomutations in antithrombin deficiency: high frequency and heterogeneous mechanisms. 

  Garrido-Rodríguez, Pedro; de-la-Morena-Barrio, Belén; Bravo-Pérez, Carlos; Cifuentes-Riquelme, Rosa; Padilla, José; Navarro, Esther; Llamas-López, María; Minano, Antonia; Teruel-Montoya, Raúl; Rodríguez-Alen, Agustín; Velasco, Francisco; Blanco, María-J; López-Fernández, María-F; Fernández-Pérez, Beatriz; Asenjo, Susana; González-Porras, José-R; Vicente, Vicente; Lozano-Almela, María-Luisa; de-la-Morena-Barrio, María-Eugenia; Corral, Javier (2026-01-29)

  Not available.
• XVII Post-ECTRIMS Meeting: Review of the New Developments Presented at the 2024 ECTRIMS Congress (II) 

  Fernández, Óscar; Ares, Adrián; Agüera, Eduardo; Aladro, Yolanda; Alonso, Ana; Arroyo, Rafael; Brieva, Luis; Calles, Carmen; Caminero, Ana-Belén; Castillo-Trivino, Tamara; Costa-Frossard, Lucienne; Eichau, Sara; Hernández, Miguel-Ángel; Landete, Lamberto; Llaneza, Miguel; Llufriu, Sara; Meca-Lallana, José-Eustasio; Meca-Lallana, Virginia; Moral, Ester; Oreja-Guevara, Celia; Prieto, José-María; Romero-Pinel, Lucía; Vilaseca, Andreu; Rodríguez-Antiguedad, Alfredo (IMR PRESS, 2026-01-21)

  Introduction: The XVII edition of the post-European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) meeting was held on 4-5 October 2024 in Madrid. This event was attended by Spanish neurologists ...
• XVII Post-ECTRIMS Meeting: Review of the New Developments Presented at the 2024 ECTRIMS Congress (I) 

  Fernández, Óscar; Ares, Adrián; Agüera, Eduardo; Aladro, Yolanda; Alonso, Ana; Arroyo, Rafael; Brieva, Luis; Calles, Carmen; Caminero, Ana-Belén; Castillo-Trivino, Tamara; Costa-Frossard, Lucienne; Eichau, Sara; Hernández, Miguel-Ángel; Landete, Lamberto; Llaneza, Miguel; Llufriu, Sara; Meca-Lallana, José-Eustasio; Meca-Lallana, Virginia; Moral, Ester; Oreja-Guevara, Celia; Prieto, José-María; Romero-Pinel, Lucía; Vilaseca, Andreu; Rodríguez-Antiguedad, Alfredo (IMR PRESS, 2026-01-21)

  Introduction: The XVII edition of the post-European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) meeting was held on 4-5 October 2024 in Madrid. This event was attended by Spanish neurologists ...
• Validation of the Institute Mutualiste Montsouris system for the stratification of laparoscopic liver resections: an international multicenter study 

  Mazzotta, Alessandro; Fuks, David; Soubrane, Olivier; Tan, Hwee-Leong; Syn, Nicholas-L; Dokmak, Safi; Gruttadauria, Salvatore; Cipriani, Federica; Zimmitti, Giuseppe; Alzoubi, Mohammad; Sugioka, Atsushi; Scatton, Olivier; Herman, Paulo; Peng, Yufu; Marino, Marco, V; Croner, Roland-S; Mazzaferro, Vincenzo; Chiow, Adrian-K-H; Sucandy, Iswanto; Ivanecz, Arpad; Choi, Sung-Hoon; Lee, Jae-Hoon; Gastaca, Mikel; Vivarelli, Marco; Giuliante, Felice; Ruzzenente, Andrea; Yong, Chee-Chien; Yin, Mengqiu; Fondevila, Constantino; Efanov, Mikhail; Morise, Zenichi; Di-Benedetto, Fabrizio; Brustia, Raffaele; Dalla-Valle, Raffaele; Boggi, Ugo; Geller, David; Belli, Andrea; Memeo, Riccardo; Mejia, Alejandro; Park, James-O; Rotellar, Fernando; Choi, Gi-Hong; Robles-Campos, Ricardo; Hasegawa, Kiyoshi; Kawaguchi, Yoshikuni; Wang, Xiaoying; Sutcliffe, Robert-P; Pratschke, Johann; Lai, Eric-C-H; Chong, Charing-C-N; D'Hondt, Mathieu; Monden, Kazuteru; López-Ben, Santiago; Kingham, T-Peter; Liu, Rong; Ferrero, Alessandro; Ettorre, Giuseppe-María; Cherqui, Daniel; Liang, Xiao; Wakabayashi, Go; Troisi, Roberto-I; Cheung, Tan-To; Sugimoto, Motokazu; Han, Ho-Seong; Long, Tran-Cong-Duy; Zhang, Wanguang; Wei, Yonggang; Aghayan, Davit-L; Edwin, Bjorn; Chen, Kuo-Hsin; Abu-Hilal, Mohammad; Aldrighetti, Luca; Goh, Brian-K-P (AME PUBLISHING COMPANY, 2026-02)

  Background: The Institut Mutualiste Montsouris (IMM) 3-level complexity classification has been validated for laparoscopic liver resection (LLR) in several studies with small sample size. However, it has not been well-validated ...

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