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03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla)

03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla)

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  • Papantoniou, Kyriaki; Castaño-Vinyals, Gemma; Espinosa, Ana; Turner, Michelle-C; Henar-Alonso-Aguado, María; Martín, Vicente; Aragones, Nuria; Pérez-Gómez, Beatriz; Miron-Pozo, Benito; Gómez-Acebo, Ines; Ardanaz, Eva; Altzibar, Jone-M; Peiro, Rosana; Tardon, Adonina; Andrés-Lorca, José; Chirlaque-López, María-Dolores; García-Palomo, Andrés; Jiménez-Moleon, José-Juan; Dierssen, Trinidad; Ederra, María; Amiano, Pilar; Pollan, Marina; Moreno, Víctor; Kogevinas, Manolis (SCANDINAVIAN JOURNAL WORK ENVIRONMENT & HEALTH, 2017-05)
    Objectives Shift work that involves circadian disruption has been associated with a higher cancer risk. Most epidemiological studies to date have focused on breast cancer risk and evidence for other common tumors is limited. ...
  • Parrilla-Almansa, Andrés; Alberto-González-Bermudez, Carlos; Sánchez-Sánchez, Silvia; Meseguer-Olmo, Luis; Martínez-Caceres, Carlos-Manuel; Martínez-Martínez, Francisco; Calvo-Guirado, José-Luis; Pinero-de-Armas, Juan-Jose; Aragoneses, Juan-Manuel; García-Carrillo, Nuria; de-Aza, Piedad-N (MDPI, 2019-04)
  • Martínez-Sánchez, Sara-María; Minguela-Puras, Alfredo; Prieto-Merino, David; Pilar-Zafrilla-Rentero, María; Abellán-Aleman, José; Montoro-García, Silvia (MDPI AG, 2017-04)
    Background and aims: Dietary studies have shown that active biopeptides provide protective health benefits, although the mediating pathways are somewhat uncertain. To throw light on this situation, we studied the effects ...
  • Meza-Meza, Mónica-R; Vizmanos-Lamotte, Barbara; Francisco-Muñoz-Valle, José; Parra-Rojas, Isela; Garaulet, Marta; Campos-López, Bertha; Montoya-Buelna, Margarita; Cerpa-Cruz, Sergio; Martínez-López, Erika; Oregon-Romero, Edith; de-la-Cruz-Mosso, Ulises (MDPI, 2019-11)
    Obesity and nutrients intake deficiencies may contribute to the clinical manifestations and inflammatory processes in systemic lupus erythematosus (SLE). The aim of this study was to assess the relationship between nutritional ...
  • López-Mínguez, Jesús; Gómez-Abellán, Purificacion; Garaulet, Marta (MDPI, 2019-11)
    (1) Background: Eating is fundamental to survival. Animals choose when to eat depending on food availability. The timing of eating can synchronize different organs and tissues that are related to food digestion, absorption, ...
  • Obon-Santacana, Mireia; Romaguera, Dora; Gracia-Lavedan, Esther; Molinuevo, Amaia; Molina-Montes, Esther; Shivappa, Nitin; Hebert, James-R; Tardon, Adonina; Castaño-Vinyals, Gemma; Moratalla, Ferran; Guino, Elisabet; Marcos-Gragera, Rafael; Azpiri, Mikel; Gil, Leire; Olmedo-Requena, Rocío; Lozano-Lorca, Macarena; Alguacil, Juan; Fernández-Villa, Tania; Martín, Vicente; Molina, Antonio-J; Ederra, María; Moreno-Iribas, Conchi; Pérez, Beatriz; Aragones, Nuria; Castello, Adela; Huerta-Castaño, José-María; Dierssen-Sotos, Trinidad; Gómez-Acebo, Ines; Molina-Barcelo, Ana; Pollan, Marina; Kogevinas, Manolis; Moreno, Víctor; Amiano, Pilar (MDPI, 2019-06)
    Inflammation and antioxidant capacity have been associated with colorectal and breast cancer. We computed the dietary inflammatory index (DII(®)), and the total dietary non-enzymatic antioxidant capacity (NEAC) and associated ...
  • McHill, Andrew-W; Czeisler, Charles-A; Phillips, Andrew-J-K; Keating, Leigh; Barger, Laura-K; Garaulet, Marta; Scheer, Frank-A-J-L; Klerman, Elizabeth-B (MDPI, 2019-03-11)
    The timing of caloric intake is a risk factor for excess weight and disease. Growing evidence suggests, however, that the impact of caloric consumption on metabolic health depends on its circadian phase, not clock hour. ...
  • Olmedo-Requena, Rocío; González-Donquiles, Carmen; Davila-Batista, Veronica; Romaguera, Dora; Castello, Adela; Molina-de-la-Torre, Antonio-Jose; Amiano, Pilar; Dierssen-Sotos, Trinidad; Guevara, Marcela; Fernández-Tardon, Guillermo; Lozano-Lorca, Macarena; Alguacil, Juan; Peiro, Rosana; Huerta-Castaño, José-María; Gracia-Lavedan, Esther; Aragones, Nuria; Fernández-Villa, Tania; Solans, Marta; Gómez-Acebo, Ines; Castaño-Vinyals, Gemma; Kogevinas, Manolis; Pollan, Marina; Martín, Vicente (MDPI, 2019-02-26)
    There are many different methods used to measure the degree of adherence to a Mediterranean diet (MD), limiting comparison and interpretation of their results. The concordance between different methodologies has been ...
  • Paredes, María-D; Romecin, Paola; Atucha, Noemi-M; O'Valle, Francisco; Castillo, Julián; Clara-Ortiz, María; García-Estañ, Joaquín (MDPI, 2018-08)
    Many studies have shown that flavonoids are effective as antihypertensive drugs in arterial hypertension. In the present work, we have analyzed the effects of some flavonoid extracts in the spontaneous hypertensive rat ...
  • Landais, Edwige; Moskal, Aurelie; Mullee, Amy; Nicolás, Genevieve; Gunter, Marc; Huybrechts, Inge; Overvad, Kim; Roswall, Nina; Affret, Aurelie; Fagherazzi, Guy; Mahamat-Saleh, Yahya; Katzke, Verena; Kuehn, Tilman; La-Vecchia, Carlo; Trichopoulou, Antonia; Valanou, Elissavet; Saieva, Calogero; de-Magistris, María-Santucci; Sieri, Sabina; Braaten, Tonje; Skeie, Guri; Weiderpass, Elisabete; Ardanaz, Eva; Chirlaque-López, María-Dolores; García, José-Ramón; Jakszyn, Paula; Rodríguez-Barranco, Miguel; Brunkwall, Louise; Huseinovic, Ena; Nilsson, Lena; Wallstroem, Peter; Bueno-de-Mesquita, Bas; Peeters, Petra-H; Aune, Dagfinn; Key, Tim; Lentjes, Marleen; Riboli, Elio; Slimani, Nadia; Freisling, Heinz (MDPI, 2018-06)
    BACKGROUND: Coffee and tea are among the most commonly consumed nonalcoholic beverages worldwide, but methodological differences in assessing intake often hamper comparisons across populations. We aimed to (i) describe ...
  • López-García, Sergio; Pecci-Lloret, María-P; Pecci-Lloret, Miguel-R; Oñate-Sánchez, Ricardo-Elías; García-Bernal, David; Castelo-Baz, Pablo; Rodríguez-Lozano, Francisco-Javier; Guerrero-Girones, Julia (MDPI, 2019-11-02)
    This study aimed to analyze the biological effects of three new bioactive materials on cell survival, migration, morphology, and attachment in vitro. ACTIVA Kids BioACTIVE Restorative (Pulpdent, Watertown, MA, USA) (Activa), ...
  • López-García, Sergio; Pecci-Lloret, Miguel-R; Guerrero-Girones, Julia; Pecci-Lloret, María-P; Lozano, Adrián; Llena, Carmen; Rodríguez-Lozano, Francisco-Javier; Forner, Leopoldo (MDPI, 2019-10)
    The aim of this study was to investigate the cytocompatibility and mineralization potential of two premixed hydraulic endodontic sealers compared with an epoxy resin-based root canal sealer. The cellular responses and ...
  • Parrilla-Almansa, Andrés; García-Carrillo, Nuria; Ros-Tarraga, Patricia; Martínez, Carlos-M; Martínez-Martínez, Francisco; Meseguer-Olmo, Luis; de-Aza, Piedad-N (MDPI, 2018-09)
    The aim of this study was to manufacture and evaluate the effect of a biphasic calcium silicophosphate (CSP) scaffold ceramic, coated with a natural demineralized bone matrix (DBM), to evaluate the efficiency of this novel ...
  • Llena, Carmen; Collado-González, Mar; Joseph-Tomas-Catala, Christopher; García-Bernal, David; Oñate-Sánchez, Ricardo-Elías; Rodríguez-Lozano, Francisco-Javier; Forner, Leopoldo (MDPI, 2018-07)
    The purpose of this study was to evaluate the diffusion capacity and the biological effects of different bleaching products on human dental pulp stem cells (hDPSCs). The bleaching gel was applied for 90, 30 or 15 min to ...
  • López-García, Sergio; Lozano, Adrián; García-Bernal, David; Forner, Leopoldo; Llena, Carmen; Guerrero-Girones, Julia; Moraleda-Jiménez, José-María; Murcia, Laura; Rodríguez-Lozano, Francisco-Javier (MDPI, 2019-08)
    Background: The aim of this study was: to evaluate the biological properties of new hydraulic materials: Bio-C Repair and Bio-C Sealer. Methods: Periodontal ligament stem cells were exposed to several dilutions of Bio-C ...
  • Medina-Mirapeix, Francesc; Bernabeu-Mora, Roberto; Sánchez-Martínez, María-Piedad; Gacto-Sánchez, Mariano; Martín-San-Agustin, Rodrigo; Montilla-Herrador, Joaquina (MDPI, 2019-07)
    Recent recommendations for chronic obstructive pulmonary disease (COPD) suggest that evaluation and management should focus on patient health status. Despite the frequency of poor health status and its negative impact on ...
  • Lucas-Ruiz, Fernando; Galindo-Romero, Caridad; Rodríguez-Ramírez, Kristy-T; Vidal-Sanz, Manuel; Agudo-Barriuso, Marta (MDPI, 2019-11)
    For years it has been known that unilateral optic nerve lesions induce a bilateral response that causes an inflammatory and microglial response in the contralateral un-injured retinas. Whether this contralateral response ...
  • Cuenca-Zamora, Ernesto-José; Ferrer-Marín, Francisca; Rivera, José; Teruel-Montoya, Raúl (MDPI, 2019-07-02)
    Platelets are anuclear cells with a short lifespan that play an essential role in many pathophysiological processes, including haemostasis, inflammation, infection, vascular integrity, and metastasis. Billions of platelets ...
  • Micillo, Raffaella; Sires-Campos, Julia; García-Borron, José-Carlos; Panzella, Lucía; Napolitano, Alessandra; Olivares, Conchi (MDPI, 2018-08)
    Caffeic acid derivatives represent promising lead compounds in the search for tyrosinase inhibitors to be used in the treatment of skin local hyperpigmentation associated to an overproduction or accumulation of melanin. ...
  • Rodríguez-Fdez, Sonia; Citterio, Carmen; Francisco-Lorenzo-Martín, L; Baltanas-Copado, Jesús; Llorente-González, Clara; Corbalán-García, Senena; Vicente-Manzanares, Miguel; Bustelo, Xose-R (MDPI, 2019-12)
    Phosphatidylinositol-5 phosphate (PI5P) and other mono-phosphoinositides (mono-PIs) play second messenger roles in both physiological and pathological conditions. Despite this, their intracellular targets and mechanisms ...

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