• Inherited Epigenetic Hallmarks of Childhood Obesity Derived from Prenatal Exposure to Obesogens 

  Nuñez-Sánchez, María-A; Jiménez-Méndez, Almudena; Suárez-Cortes, María; Martínez-Sánchez, María-A; Sánchez-Solis, Manuel; Blanco-Carnero, José-E; Ruiz-Alcaraz, Antonio-J; Ramos-Molina, Bruno (Multidisciplinary Digital Publishing Institute (MDPI), 2023)
• Efficacy of a Dietary Supplement Extracted from Persimmon (Diospyros kaki L.f.) in Overweight Healthy Adults: A Randomized, Double-Blind, Controlled Clinical Trial 

  Pérez-Pinero, Silvia; Muñoz-Carrillo, Juan-Carlos; Echepare-Taberna, Jon; Herrera-Fernández, Cristina; Muñoz-Camara, Macarena; avila-Gandía, Vicente; López-Román, Francisco-Javier (MDPI, 2024-12)

  A single-center, randomized, double-blind, and placebo-controlled clinical trial assessed the efficacy in improving body composition and in weight management of a dietary supplement consisting of 400 mg of a standardized ...
• Effect of Silibinin on Human Pancreatic Lipase Inhibition and Gut Microbiota in Healthy Volunteers: A Randomized Controlled Trial 

  Ponce-Martínez, Cristina; Murcia-García, Elena; Sánchez, Horacio-Pérez; Milagro, Fermin-I; Riezu-Boj, José-I; Ramos-Molina, Bruno; Gallego, María-Gómez; Zamora, Salvador; Cutillas, Ruben-Canavate; Morante, Juan-José-Hernández (MDPI, 2024-12)

  Thistle (Onopordum acanthium) has been traditionally employed for liver protection. However, we recently identified silibinin, the main bioactive compound of thistle extract, as an in vitro pancreatic lipase inhibitor, ...
• Comparison of n-3 PUFA-Enriched vs. Olive-Oil-Based Lipid Emulsion on Oxidative Stress and Inflammatory Response in Critically Ill Post-Surgery Adults: Secondary Analysis of a Randomized Controlled Trial 

  Cuartero-Corbalán, Nerea; Martínez-Lozano-Aranaga, Fatima; Gómez-Ramos, María-Jesús; Gómez-Sánchez, María-B; Aviles-Plaza, Francisco-V; Nunez-Sánchez, María-A; Morillas-Ruiz, Juana-M (MDPI, 2024-11)

  Malnutrition in critically ill patients represents a major concern as it can lead to adverse outcomes including increased morbidity and mortality. These patients exhibit an impaired immune response accompanied by increased ...
• Whole Blood Transcriptome Analysis in Congenital Anemia Patients 

  Sánchez-Villalobos, María; Banos, Eulalia-Campos; Martínez-Balsalobre, Elena; Navarro-Ramírez, Verónica; Videla, María-Asuncion-Beltran; Pinilla, Miriam; Guillén-Navarro, Encarna; Salido-Fierrez, Eduardo; Pérez-Oliva, Ana-Belén (MDPI, 2024-11)

  Congenital anemias include a broad range of disorders marked by inherent abnormalities in red blood cells. These abnormalities include enzymatic, membrane, and congenital defects in erythropoiesis, as well as hemoglobinopathies ...
• In Vitro Study of the Differential Anti-Inflammatory Activity of Dietary Phytochemicals upon Human Macrophage-like Cells as a Previous Step for Dietary Intervention 

  Ruiz-Alcaraz, Antonio-J; Baquero, Lorena; Pérez-Munar, Paula-Martínez; Oliva-Bolarín, Alba; Sánchez-Martínez, María-A; Ramos-Molina, Bruno; Nunez-Sánchez, María-A; Moreno, Diego-A (MDPI, 2024-10)

  Chronic inflammatory diseases pose a substantial health challenge globally, significantly contributing to morbidity and mortality. Addressing this issue requires the use of effective anti-inflammatory strategies with fewer ...
• Health-Related Quality of Life in Long-Term Colorectal Cancer Survivors 

  Marcos-Delgado, Alba; Martín-Sánchez, Vicente; Molina-Barcelo, Ana; Alonso-Molero, Jessica; Pérez-Gómez, Beatriz; Pollan, Marina; Aragones, Nuria; Ederra-Sanza, María; Fernández-Tardon, Guillermo; Binefa, Gemma; Moreno, Víctor; Barrios-Rodríguez, Rocio; Amiano, Pilar; Huerta-Castaño, José-María; Teso, Enrique-Pastor; Alguacil, Juan; Castaño-Vinyals, Gemma; Kogevinas, Manolis; de-la-Torre, Antonio-José-Molina (MDPI, 2024-10)

  The aim of our study is to evaluate the relationship between sociodemographic and clinical characteristics of individuals with Colorectal Cancer (CRC), tumour-intrinsic characteristics and treatment received with health-related ...
• KMT2A Rearrangements in Leukemias: Molecular Aspects and Therapeutic Perspectives 

  Guarnera, Luca; D'Addona, Matteo; Bravo-Pérez, Carlos; Visconte, Valeria (MDPI, 2024-08)

  KMT2A (alias: mixed-lineage leukemia [MLL]) gene mapping on chromosome 11q23 encodes the lysine-specific histone N-methyltransferase 2A and promotes transcription by inducing an open chromatin conformation. Numerous genomic ...
• Effectiveness of Enriched Milk with Ashwagandha Extract and Tryptophan for Improving Subjective Sleep Quality in Adults with Sleep Problems: A Randomized Double-Blind Controlled Trial 

  Pérez-Pinero, Silvia; Muñoz-Carrillo, Juan-Carlos; Echepare-Taberna, Jon; Muñoz-Camara, Macarena; Herrera-Fernández, Cristina; Avila-Gandía, Vicente; Ladreda, María-Heres-Fernández; Martínez, Javier-Menendez; López-Román, Francisco-Javier (MDPI, 2024-09)

  A randomized, double-blind and controlled study was conducted to assess the effectiveness of the intake of 250 mL of lactose-free skimmed milk enriched with ashwagandha (Withania somnifera) alone or combined with tryptophan ...
• Quantification of Photoreceptors' Changes in a Diabetic Retinopathy Model with Two-Photon Imaging Microscopy 

  Bautista-Elivar, Nazario; Avilés-Trigueros, Marcelino; Bueno, Juan-M (MDPI, 2024-08)

  Emerging evidence suggests that retinal neurodegeneration is an early event in the pathogenesis of diabetic retinopathy (DR), preceding the development of microvascular abnormalities. Here, we assessed the impact of ...
• New Potential Pharmacological Options for Endometriosis Associated Pain 

  García-Izquierdo, Laura; Marín-Sánchez, Pilar; García-Penarrubia, Pilar; Martínez-Esparza, María (MDPI, 2024-07)

  Endometriosis is a chronic inflammatory disorder characterized by the abnormal growth of endometrial-like tissue outside the uterine cavity, affecting 10-15% of women of reproductive age. Pain is the most common symptom. ...
• Antibacterial Effect of Spanish Honeys of Different Botanical Origins against Staphylococcus epidermidis 

  Nunez-Gómez, Vanesa; Mateo, Marta-San; Sánchez-Martínez, Lorena; Periago, María-Jesús (MDPI, 2024-06)

  Honey is traditionally used for its medicinal properties attributed to its antibacterial and antioxidant effects. It is considered a natural alternative to conventional antibiotics. This effect has been attributed to their ...
• HELIX Syndrome, a Claudinopathy with Relevant Dermatological Manifestations: Report of Two New Cases 

  Martínez-Romero, María-Carmen; Hernández-Contreras, María-Encarnación; Bafalliu-Vidal, Juan-Antonio; Barreda-Sánchez, María; Martínez-Menchón, Teresa; Cabello-Chaves, Virginia; Guillén-Navarro, Encarna (MDPI, 2024-06)

  HELIX syndrome (Hypohidrosis-Electrolyte disturbances-hypoLacrimia-Ichthyosis-Xerostomia) (MIM#617671) (ORPHA:528105), described in 2017, is due to an abnormal claudin 10 b protein, secondary to pathogenic CLDN10 variants. ...
• Attitudes, Self-Confidence, and Knowledge of Primary Care Professionals towards School Bullying 

  Celdrán-Navarro, María-del-Carmen; Jiménez-Ruiz, Ismael; Leal-Costa, César; Moore, James-R; López-Barranco, Pedro-Jose (MDPI, 2024-06)

  Attitudes, practices, and knowledge about bullying were evaluated in a sample of 274 primary care professionals, including general practitioners, pediatricians, community, pediatric and school nurses, and residents of these ...
• Cross-Cultural Validation of the Healthcare Provider's Practices, Attitudes, Self-Confidence, and Knowledge Regarding Bullying Questionnaire 

  del-Carmen-Celdrán-Navarro, María; Jiménez-Ruiz, Ismael; Myriam-Seva-Llor, A; Moore, James-R; Leal-Costa, César (MDPI, 2024-03)

  How can we know the reality of the context of bullying in the field of primary health care? The aim of this study is to obtain a validated and reliable tool that allows measurement of the involvement of primary care ...
• Inflammation in Development and Aging: Insights from the Zebrafish Model 

  Mastrogiovanni, Marta; Martínez-Navarro, Francisco-Juan; Bowman, Teresa-V; Cayuela, María-L (MDPI, 2024-02)

  Zebrafish are an emergent animal model to study human diseases due to their significant genetic similarity to humans, swift development, and genetic manipulability. Their utility extends to the exploration of the involvement ...
• The Microbiota in Long COVID 

  Álvarez-Santacruz, Carmen; Tyrkalska, Sylwia-D; Candel, Sergio (MDPI, 2024-01)

  Interest in the coronavirus disease 2019 (COVID-19) has progressively decreased lately, mainly due to the great effectivity of vaccines. Furthermore, no new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ...
• Lipidomes in Cadaveric Decomposition and Determination of the Postmortem Interval: A Systematic Review 

  Caballero-Moreno, Leticia; Luna, Aurelio; Legaz, Isabel (MDPI, 2024-01)

  Lipids are a large group of natural compounds, together with proteins and carbohydrates, and are essential for various processes in the body. After death, the organism's tissues undergo a series of reactions that generate ...
• Factor XI in Carriers of Antiphospholipid Antibodies: Elevated Levels Associated with Symptomatic Thrombotic Cases, While Low Levels Linked to Asymptomatic Cases 

  Pagan-Escribano, Javier; Corral, Javier; Minano, Antonia; Padilla, José; Roldan-Schilling, Vanesa; Hernández-Vidal, María-Julia; Lozano, Jesús; de-la-Morena-barrio, Isabel; Vicente, Vicente; Lozano, María-Luisa; Herranz, María-Teresa; de-la-Morena-barrio, María-Eugenia (MDPI, 2023-11)

  Antiphospholipid syndrome (APS) is a thromboinflammatory disorder caused by circulating antiphospholipid autoantibodies (aPL) and characterized by an increased risk of thrombotic events. The pathogenic mechanisms of these ...
• Snijders Blok-Campeau Syndrome: Description of 20 Additional Individuals with Variants in CHD3 and Literature Review 

  Pascual, Patricia; Tenorio-Castaño, Jair; Mignot, Cyril; Afenjar, Alexandra; Arias, Pedro; Gallego-Zazo, Natalia; Parra, Alejandro; Miranda, Lucía; Cazalla, Mario; Silvan, Cristina; Heron, Delphine; Keren, Boris; Popa, Ioana; Palomares, María; Rikeros, Emi; Ramos, Feliciano-J; Almoguera, Berta; Ayuso, Carmen; Swafiri, Saoud-Tahsin; Barbero, Ana-Isabel-Sánchez; Srinivasan, Varunvenkat-M; Gowda, Vykuntaraju-K; Morleo, Manuela; Nigro, Vicenzo; D'Arrigo, Stefano; Ciaccio, Claudia; Mesa, Carmen-Martín; Paumard, Beatriz; Guillén, Gema; Anton, Ana-Teresa-Serrano; Jiménez, Marta-Domínguez; Seidel, Verónica; Suárez, Julia; Cormier-Daire, Valerie; Nevado, Julián; Lapunzina, Pablo (MDPI, 2023-09)

  Snijders Blok-Campeau syndrome (SNIBCPS, OMIM# 618205) is an extremely infrequent disease with only approximately 60 cases reported so far. SNIBCPS belongs to the group of neurodevelopmental disorders (NDDs). Clinical ...

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