Repositorio Dspace

Envíos recientes

03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla): Envíos recientes

  • Single spectral flow cytometry panel for simultaneous detection of hematopoietic stem, progenitor, and mature lineages in mouse bone marrow 
    Girondier, Lea; Richaud, Manon; Grenier, Julien-Mp; Pérez-Oliva, Ana-Belén; Van-van-der-Wijst, Jenny; Aurrand-Lions, Michel; de-Grandis, María; Lachaud, Christophe; Fauriat, Cyril; Braud, Laura (FRONTIERS MEDIA SA, 2026-03-18)
  • Innovative reproductive management in rabbits: GnRH-free insemination with specifically designed cannulas for nulliparous and multiparous does 
    Castillo, Juan-José; Vicente, José-Salvador; Marco-Jiménez, Francisco; Aguilar, Enrique; Moros-Nicolás, Carla; Viudes-de-Castro, María-Pilar (FRONTIERS MEDIA SA, 2026-03-17)
  • Correction: Innovative reproductive management in rabbits: GnRH-free insemination with specifically designed cannulas for nulliparous and multiparous does 
    Castillo, Juan-José; Vicente, José-Salvador; Marco-Jiménez, Francisco; Aguilar, Enrique; Moros-Nicolás, Carla; Viudes-de-Castro, María-Pilar (FRONTIERS MEDIA SA, 2026-03-31)
  • Eggshell morphology, structure, and nanomechanical properties of diapausing embryos in sessile rotifers 
    Franch-Meneu, Vicente; Wallace, Robert-L; Rodríguez-Quesada, Laria; Saenz-Arce, Giovanni; Pastor, Luis-Miguel (SPRINGER, 2026-05-27)
  • Metabolic buffering restricts phenotype switching in melanoma 
    Ramírez-Sánchez, Ana; Jociles-Ortega, Miguel; García-Martínez, José-Manuel; Torrens-Martínez, Irene; Martínez-Useros, Javier; Louphrasitthiphol, Pakavarin; Sweeney, Mollie; Morente-Carrasco, Ana; Ruiz-Reyes, Sergio; Redondo-Díaz, Nerea; Olmos-de-Blas, Teresa; Fernández-Acenero, María-Jesús; Rodríguez-López, José-N; Soga, Tomoyoshi; White, Richard-M; Goding, Colin-R; Sánchez-del-Campo, Luis; García-Jiménez, Custodia; Chocarro-Calvo, Ana (SPRINGERNATURE, 2026-07-15)
    The impact of the metabolic microenvironment on epigenetically plastic cancer cells underpins phenotypic heterogeneity, a major cause of metastasis and therapy resistance. Nutrient limitation is a key microenvironmental ...
  • Exercise Training in Hypertrophic Cardiomyopathy: A Systematic Review, Meta-analysis, and Meta-regression 
    Bayonas-Ruiz, Adrián; Gimeno-Blanes, Juan-Ramón; Muñoz-Franco, Francisca-M; Sabater-Molina, María; Bonacasa, Barbara (SPRINGER, 2026-07-15)
    BACKGROUND: A paradigm shift has emerged regarding exercise participation in patients with hypertrophic cardiomyopathy (HCM), with recent studies suggesting that structured training may improve functional capacity and ...
  • Mutational profile and cardiovascular risk factors impact prognosis in triple-negative essential thrombocythemia 
    Carreño-Tarragona, Gonzalo; Gil-Manso, Rodrigo; Hernández-Boluda, Juan-Carlos; Martínez-Ávila, José-Carlos; Bellosillo, Beatriz; Pérez-López, Raúl; Segura, Adrián; Ferrer-Marín, Francisca; Arellano-Rodrigo, Eduardo; Angona, Anna; García-Gutiérrez, Valentín; Noya, María-Soledad; Blanco, Ángela; Zamora, Lurdes; Navarro, Miguel; Senin, Alicia; Magro, Elena; Pastor-Galan, Irene; Mata-Vázquez, María-Isabel; Morales, María-Luz; Cuevas, Beatriz; Velez, Patricia; Mora, Elvira; Martínez-Bilbao, Cristina; Colmenares, Rafael; Alonso, Juan-Manuel; Pérez-Encinas, Manuel; Caballero-Navarro, Gonzalo; Cortes, Miguel-Ángel; Santaliestra, Marta; Raya, José-María; Blanco-Sánchez, Alberto; Hernández-Rivas, Jesus-María; Martínez-López, Joaquín; Ayala, Rosa; Álvarez-Larran, Alberto (SPRINGERNATURE, 2026-07-13)
    Triple-negative essential thrombocythemia (TN-ET) represents a diagnostic and therapeutic challenge. The aim of the present study was to identify prognostic factors useful for tailoring treatment. 241 TN-ET patients with ...
  • Design and Technical Validation of a Novel O2 Mixed Fitting for Dual Connection in Medical Oxygen Delivery Systems 
    Quintero-Osorio, Óscar-Iván; Basancelebi, Berkan; dos-Santos, Elinaldo-da-Conceicao; Sergio-I-Prada,; Lemos, David-Alexander; Domínguez, Andres-Felipe; Esquinas-Rodríguez, Antonio (DOVE MEDICAL PRESS LTD, 2026-07)
    BACKGROUND: Medical oxygen delivery systems require adaptable connection interfaces capable of supporting different clinical configurations during oxygen therapy. Integrating multifunctional connection mechanisms within a ...
  • Assessment of diabetes self-management education guideline content across Spanish regions: a document-based comparative analysis. 
    Moore, James-Richard; Roldán-Chicano, María-Teresa; Cebrián-Cuenca, Ana-María; Esteban-Flores, Ana (ELSEVIER, 2026-07)
    OBJECTIVE: This study aims to evaluate the content, structure, and alignment with international standards of Diabetes Self-Management Education guidelines across Spain's regional healthcare systems. It focuses on comparing ...
  • The cult of the external validation set: undertraining is only half of the radiomics validation crisis 
    García-Hidalgo, Clemente (SPRINGER, 2026-07-09)
  • Circulating metabolites and fatty acids associated with ultra-processed food consumption: results from the EPIC study 
    Blanco-López, Jessica; Yammine, Sahar; Rothwell, Joseph-A; His, Mathilde; Biessy, Carine; Keski-Rahkonen, Pekka; Chimera, Bernadette; Jacobs, Inarie; Al-Nahas, Aline; Koc-Cakmak, Emine; Robinson, Oliver; Morales-Berstein, Fernanda; Cairat, Manon; Chang, Kiara; Vamos, Eszter-P; Millet, Christopher; Bertazzi-Levy, Renata; Rauber, Fernanda; Rinaldi, Sabina; Vineis, Paolo; Harewood, Rhea; Sánchez, María-José; Guevara, Marcela; Huerta-Castaño, José-María; Crous-Bou, Marta; Borch-Ibsen, Daniel; Dahm, Christina-C; Olsen, Anja; Kyro, Cecilie; Bendinelli, Benedetta; Gargano, Giuliana; Tumino, Rosario; Sacerdote, Carlotta; Pasanisi, Fabrizio; van-der-Schouw, Yvonne; Mancini, Francesca; Frenoy, Pauline; Marqués, Chloe; Skeie, Guri; Brustad, Magritt; Nicolas, Genevieve; Papadimitriou, Nikos; Wu, Diana; González-Gil, Esther-M; Gunter, Marc-J; Ferrari, Pietro; Kliemann, Nathalie; Huybrechts, Inge (TAYLOR & FRANCIS INC, 2026-07-06)
    Emerging evidence links consumption of ultra-processed foods (UPF) to higher risks of non-communicable diseases and mortality, but the underlying mechanisms remain unclear. This study aimed to identify molecular signatures ...
  • CV risk: if you aren't testing ACR, you aren't seeing the full picture 
    Cebrián-Cuenca, Ana-María; Wheeler, David-C; Marx, Nikolaus; Levin, Adeera (TAYLOR & FRANCIS LTD, 2026-08-18)
    Chronic kidney disease (CKD) remains a hidden epidemic, under-recognized and under-diagnosed, despite widespread recognition of the benefits of systematic screening of at-risk individuals and early diagnosis. CKD is an ...
  • The peripheral immune landscape of human breast cancer 
    García-Torralba, Esmeralda; Buque, Aitziber; Galluzzi, Lorenzo (TAYLOR & FRANCIS INC, 2026-12-31)
    The clinical management of patients with breast cancer is largely dictated by tumor stage, disease subtype and (at least in some settings) specific molecular features thereof (e.g., BRCA1 mutations, PD-L1 positivity). ...
  • Moderate NEFA reprogram early follicular development and oocyte competence: evidence for a targetable redox mechanism 
    Rojo-Fleming, Camila; Di-Berardino, Chiara; Peserico, Alessia; Canciello, Angelo; Rapini, Chiara-Camerano-Spelta; Sacchetti, Gianna; Capacchietti, Giulia; D'Antonio, Veronica; Angelino, Donato; Serafini, Mauro; Cánovas-Bernabé, Sebastián; Barboni, Barbara (FRONTIERS MEDIA SA, 2026-06-17)
    INTRODUCTION: Elevated circulating non-esterified fatty acids (NEFA), a hallmark of metabolic stress and negative energy balance, are increasingly associated with reduced female fertility. While most studies focus on late ...
  • Associations of proteomic age clocks with lifestyle risk factors, incident chronic diseases and mortality in two European cohorts 
    Robinson, Oliver; Xiao, Han; Homann, Jan; Viallon, Vivian; Ferrari, Pietro; Frank, Philipp; Huerta-Castaño, José-María; Jiménez-Zabala, Ana; Kaaks, Rudolf; Katzke, Verena; Kivimaki, Mika; Langenberg, Claudia; Lau, Chung-Ho-E; Middleton, Lefkos; Onland-Moret, N-Charlotte; Panico, Salvatore; Prizment, Anna; Ricceri, Fulvio; Sánchez, María-José; Smith-Byrne, Karl; Verschuren, W-M-Monique; Vermeulen, Roel; Vineis, Paolo; Wang, Shuo; Wareham, Nick; Lill, Christina-M; Riboli, Elio; Gunter, Marc-J (SPRINGERNATURE, 2026-06-29)
    Assessment of biological aging using proteomic clocks may enhance risk prediction and elucidate the molecular links between aging and chronic diseases. Here, among 17,473 participants of the European Prospective Investigation ...
  • Platelet proteome links metabolism to reactivity in Essential Thrombocythemia. 
    Guerrero-Carreno, Xiomara; Smits, Sanne; Esteban-Lasso, Alfonso; Samiotaki, Martina; Navarro, Virtu-Calabuig; Iborra, Francisco-Jose; Rantanen, Frida; Álvarez-Larran, Alberto; Angona-Figueras, Anna; Bellosillo, Beatriz; Saen-Marin, Adolfo-J; García-Gutiérrez, Valentín; Dekkers, Dick; Demmers, Jeroen; Ferrer-Marín, Francisca; Hernández-Boluda, Juan-Carlos; Matsakas, Antonios; Benavente-Cuesta, Celina; Vandenberghe, Peter; Papadopoulos, Petros (ELSEVIER, 2026-06)
    Essential thrombocythemia (ET) is a myeloproliferative neoplasm in which JAK2, CALR, and MPL mutations are associated with distinct clinical phenotypes. Here, we analyzed the platelet proteome of ET patients by MS, combined ...
  • Polyphenols increase circulating lipids but improve LDL particle quality and reduce LDL oxidation in postmenopausal women: metabotype- and age-dependent effects in a randomised, placebo-controlled crossover trial 
    García-Nicolas, María; Jarrin-Orozco, María-Paula; Romo-Vaquero, María; Carrascosa, Concepcion; Avilés-Plaza, Francisco; Martínez-Villanueva, Miriam; Noguera, José-Antonio; Ávila-Gálvez, María-Ángeles; Espin, Juan-Carlos (SPRINGER HEIDELBERG, 2026-08)
    PURPOSE: Menopause increases cardiometabolic risk via dyslipidaemia, oxidative stress, and low-grade inflammation. Polyphenols may modulate these processes, but human evidence is inconsistent. We investigated the effects ...
  • Common and rare variants in complement genes as biomarkers of COVID-19 infection and severity. A lesson to learn for emerging pathogens 
    de-la-Morena-Barrio, María-Eugenia; van-den-Rym, Ana; Escorial-Sanz, Olga; Corvillo, Fernando; García-Sánchez, Rosario; González-Sánchez, Laura; Muñoz-Barrera, Adrián; González-Montelongo, Rafaela; Lorenzo-Salazar, José-Miguel; Flores, Carlos; de-Andres-Martin, Ana; Rodríguez-Gallego, Carlos; Allende, Luis; Alsina, Laia; Sánchez-Ramon, Silvia; López-Collazo, Eduardo; López-Trascasa, Margarita; Sánchez-Corral, Pilar; Pérez-de-Diego, Rebeca; Corral, Javier; López-Lera, Alberto (FRONTIERS MEDIA SA, 2026-06-11)
    INTRODUCTION: The first wave of Coronavirus disease 2019 (COVID-19), driven by the global emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), severely affected Spain with high infection and mortality ...
  • Exploring mechanisms of scar-free skin wound healing in adult zebrafish in comparison to mouse 
    Kucukaylak, Ismail; Halwas, Kai; Martínez-Morcillo, Francisco-Javier; Reiche, Nils; Metzger, Manuel; Comelli, Petra; Voigt, Birgit; Brinckmann, Jurgen; Eming, Sabine; Hammerschmidt, Matthias (PUBLIC LIBRARY SCIENCE, 2026-06-24)
    Adult zebrafish have the ability to perfectly regenerate their skin after injury without leaving a scar behind. Yet, they intermediately form a collagen-rich granulation tissue that later fully regresses. In contrast, adult ...
  • Immune Markers and Risk of Pancreatic Cancer in the European EPIC Cohort 
    Katzke, Verena; Chen, Yue; Dutta, Srimanti; Canzian, Federico; Andersen, Julie-Louise-Munk; Rostgaard-Hansen, Agnetha-Linn; Bouteille, Lea; Rebours, Vinciane; Truong, Therese; Schulze, Matthias-B; Bendinelli, Benedetta; Pala, Valeria; Simeon, Vittorio; Tumino, Rosario; Sacerdote, Carlotta; Vermeulen, Roel; Kolijn, P-Martijn; Elias, Sjoerd-G; Crous-Bou, Marta; Sánchez, María-José; Jiménez-Zabala, Ana; Huerta-Castaño, José-María; Guevara, Marcela; Wareham, Nick; Breeur, Marie; Johansson, Mattias; Yarmolinsky, James; Campa, Daniele; Kaaks, Rudolf (WILEY, 2026-06-23)
    The immune system is a major driver in pancreatic cancer development. Several prospective cohort studies have found associations for single immune system-derived proteins such as IL6 or CRP, but results are inconclusive, ...

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