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Listar 03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla) por fecha de publicación

Listar 03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla) por fecha de publicación

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  • Weight change in middle adulthood and risk of cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort 
    Christakoudi, Sofia; Pagoni, Panagiota; Ferrari, Pietro; Cross, Amanda-J; Tzoulaki, Ioanna; Muller, David-C; Weiderpass, Elisabete; Freisling, Heinz; Murphy, Neil; Dossus, Laure; Turzanski-Fortner, Renee; Agudo, Antonio; Overvad, Kim; Pérez-Cornago, Aurora; Key, Timothy-J; Brennan, Paul; Johansson, Mattias; Tjonneland, Anne; Halkjaer, Jytte; Boutron-Ruault, Marie-Christine; Artaud, Fanny; Severi, Gianluca; Kaaks, Rudolf; Schulze, Matthias-B; Bergmann, Manuela-M; Masala, Giovanna; Grioni, Sara; Simeon, Vittorio; Tumino, Rosario; Sacerdote, Carlotta; Skeie, Guri; Rylander, Charlotta; Borch, Kristin-Benjaminsen; Quiros, JRamón; Rodríguez-Barranco, Miguel; Chirlaque-López, María-Dolores; Ardanaz, Eva; Amiano, Pilar; Drake, Isabel; Stocks, Tanja; Haggstrom, Christel; Harlid, Sophia; Ellingjord-Dale, Merete; Riboli, Elio; Tsilidis, Konstantinos-K (Wiley, 01/04/2021)
    Obesity is a risk factor for several major cancers. Associations of weight change in middle adulthood with cancer risk, however, are less clear. We examined the association of change in weight and body mass index (BMI) ...
  • A Randomized Trial of Dolutegravir Plus Darunavir/Cobicistat as a Switch Strategy in HIV-1-Infected Patients With Resistance to at Least 2 Antiretroviral Classes 
    Santos,Jose-R; Domingo,Pere; Portilla,Joaquin; Gutierrez,Felix; Imaz,Arkaitz; Vilchez,Helem; Curran,Adria; Valcarce-Pardeiro,Nieves; Payeras,Antoni; Bernal,Enrique; Montero-Alonso,Marta; Yzusqui,Miguel; Clotet,Bonaventura; Videla,Sebastia; Molto,Jose; Par (OXFORD UNIV PRESS INC, 01/11/2023)
    Background. Suppressed patients with drug-resistant HIV-1 require effective and simple antiretroviral therapy to maintain treatment adherence and viral suppression.Methods. This randomized, open-label, noninferiority, ...
  • Alpha retinal ganglion cells in pigmented mice retina: number and distribution 
    Gallego-Ortega,Alejandro; Norte-Munoz,Maria; Di-Pierdomenico,Johnny; Aviles-Trigueros,Marcelino; de-la-Villa,Pedro; Javier-Valiente-Soriano,Francisco; Vidal-Sanz,Manuel (FRONTIERS MEDIA SA, 01/12/2022)
    BackgroundUp to 30% of breast cancer (BC) patients treated with neoadjuvant chemotherapy (NCT) will relapse. Our objective was to analyze the predictive capacity of several markers associated with immune response and cell ...
  • Diet-wide association study of 92 foods and nutrients and lung cancer risk in the European Prospective Investigation into Cancer and Nutrition study and the Netherlands Cohort Study 
    Heath, Alicia-K; Muller, David-C; van-den-Brandt, Piet-A; Critselis, Elena; Gunter, Marc; Vineis, Paolo; Weiderpass, Elisabete; Boeing, Heiner; Ferrari, Pietro; Merritt, Melissa-A; Rostgaard-Hansen, Agnetha-L; Tjonneland, Anne; Overvad, Kim; Katzke, Verena; Srour, Bernard; Masala, Giovanna; Sacerdote, Carlotta; Ricceri, Fulvio; Pasanisi, Fabrizio; Bueno-de-Mesquita, Bas; Downward, George-S; Skeie, Guri; Sandanger, Torkjel-M; Crous-Bou, Marta; Rodríguez-Barranco, Miguel; Amiano, Pilar; Huerta, José-María; Ardanaz, Eva; Drake, Isabel; Johansson, Mikael; Johansson, Ingegerd; Key, Tim; Papadimitriou, Nikos; Riboli, Elio; Tzoulaki, Ioanna; Tsilidis, Konstantinos-K (Wiley, 01/12/2022)
    It is unclear whether diet, and in particular certain foods or nutrients, are associated with lung cancer risk. We assessed associations of 92 dietary factors with lung cancer risk in 327-790 participants in the European ...
  • A Novel Substituted Benzo[g]quinoxaline-Based Cyclometalated Ru(II) Complex as a Biocompatible Membrane-Targeted PDT Colon Cancer Stem Cell Agent 
    Marco,Alicia; Kasparkova,Jana; Bautista,Delia; Kostrhunova,Hana; Cutillas,Natalia; Markova,Lenka; Novohradsky,Vojtech; Ruiz,Jose; Brabec,Viktor (AMER CHEMICAL SOC, 02/12/2024)
    Herein, we describe and investigate biological activity of three octahedral ruthenium(II) complexes of the type [Ru(C boolean AND N)(phen)2]+, RuL1-RuL3, containing a pi-expansive cyclometalating substituted benzo[g]quinoxaline ...
  • A Body Shape Index (ABSI) achieves better mortality risk stratification than alternative indices of abdominal obesity: results from a large European cohort 
    Christakoudi,Sofia; Tsilidis,Konstantinos-K; Muller,David-C; Freisling,Heinz; Weiderpass,Elisabete; Overvad,Kim; Soederberg,Stefan; Haeggstroem,Christel; Pischon,Tobias; Dahm,Christina-C; Zhang,Jie; Tjonneland,Anne; Halkjaer,Jytte; MacDonald,Conor; Boutro (NATURE PORTFOLIO, 03/09/2020)
    Abdominal and general adiposity are independently associated with mortality, but there is no consensus on how best to assess abdominal adiposity. We compared the ability of alternative waist indices to complement body mass ...
  • A spatiotemporal model of firearm ownership in the United States 
    Barak-Ventura,Roni; Marin,Manuel-Ruiz; Porfiri,Maurizio (CELL PRESS, 12/08/2022)
    Firearm injury is a major public health crisis in the United States, where more than 200 people sustain a nonfatal firearm injury and more than 100 people die from it every day. To formulate policy that minimizes firearm-related ...
  • A first-year melon/cowpea intercropping system improves soil nutrients and changes the soil microbial community 
    Cuartero,Jessica; Antonio-Pascual,Jose; Vivo,Juana-Maria; Ozbolat,Onurcan; Sanchez-Navarro,Virginia; Egea-Cortines,Marcos; Zornoza,Raul; Martinez-Mena,Maria; Garcia,Eloisa; Ros,Margarita (ELSEVIER, 15/04/2022)
    The melon/cowpea intercropping system can be a specific and efficient cropping pattern in a horticultural field. Intercropping systems contribute to the optimization of land use, fostering sustainable and efficient ...
  • (R,S)-Equol 7-¿-D-glucuronide, but not other circulating isoflavone metabolites, modulates migration and tubulogenesis in human aortic endothelial cells targeting the VEGF pathway 
    Gimenez-Bastida,Juan-Antonio; Avila-Galvez,Maria-angeles; Martinez-Lopez,Alicia; Garcia-Moreno,Diana; Espin,Juan-Carlos; Gonzalez-Sarrias,Antonio (ROYAL SOC CHEMISTRY, 15/07/2024)
    Current knowledge indicates that the consumption of isoflavone-rich foodstuffs can have a beneficial impact on cardiovascular health. To what extent these isoflavones act as the main actors of that benefit is less clear. ...
  • Dietary intake of advanced glycation endproducts and risk of hepatobiliary cancers: A multinational cohort study 
    Mayen, Ana-Lucia; Aglago, Elom-K; Knaze, Viktoria; Cordova, Reynalda; Schalkwijk, Casper-G; Wagner, Karl-Heinz; Aleksandrova, Krasimira; Fedirko, Veronika; Keski-Rahkonen, Pekka; Leitzmann, Michael-F; Katzke, Verena; Srour, Bernard; Schulze, Matthias-B; Masala, Giovanna; Krogh, Vittorio; Panico, Salvatore; Tumino, Rosario; Bueno-de-Mesquita, Bas; Brustad, Magritt; Agudo, Antonio; Chirlaque-López, María-Dolores; Amiano, Pilar; Ohlsson, Bodil; Ramne, Stina; Aune, Dagfinn; Weiderpass, Elisabete; Jenab, Mazda; Freisling, Heinz (Wiley, 15/08/2021)
    Advanced glycation endproducts (AGEs) may contribute to liver carcinogenesis because of their proinflammatory and prooxidative properties. Diet is a major source of AGEs, but there is sparse human evidence on the role of ...
  • 3D calcium silicophosphate porous scaffold: In vitro and in vivo response 
    Ros-Tarraga,Patricia; Martinez,Carlos-M; Rodriguez,Miguel-A; De-Aza,Piedad-N (ELSEVIER SCI LTD, 15/12/2022)
    The elderly population (65 years and older) is expected to increase from 524 million people in 2010 to 1.5 billion by 2050, with the corresponding increase in bone-related and joint damage problems. Many of these problems ...
  • 13th Post-ECTRIMS Meeting: review of the new developments presented at the 2020 ECTRIMS Congress (II) 
    Fernandez,Oscar; Montalban,Xavier; Aladro,Yolanda; Alonso,Ana; Arroyo,Rafael; Calles,Carmen; Castillo-Trivino,Tamara; Comabella,Manuel; Costa-Frossard,Lucienne; Forero,Lucia; Ginestal,Ricardo; Landete,Lamberto; Llaneza,Miguel; Llufriu,Sara; Luisa-Martinez (REVISTA DE NEUROLOGIA, 16/06/2021)
    A well-documented method and experimental design are essential to ensure the reproducibility and reliability in animal research. Experimental studies using exercise programs in animal models have experienced an exponential ...
  • A comparison of synthetic data generation and federated analysis for enabling international evaluations of cardiovascular health 
    Azizi,Zahra; Lindner,Simon; Shiba,Yumika; Raparelli,Valeria; Norris,Colleen-M; Kublickiene,Karolina; Herrero,Maria-Trinidad; Kautzky-Willer,Alexandra; Klimek,Peter; Gisinger,Teresa; Pilote,Louise; El-Emam,Khaled (NATURE PORTFOLIO, 17/07/2023)
    Sharing health data for research purposes across international jurisdictions has been a challenge due to privacy concerns. Two privacy enhancing technologies that can enable such sharing are synthetic data generation (SDG) ...
  • Adenylate kinase 9 is essential for sperm function and male fertility in mammals 
    O'Callaghan,Fiena; Navarrete-Lopez,Paula; Stiavnicka,Miriama; Sanchez,Jose-M; Maroto,Maria; Pericuesta,Eva; Fernandez-Gonzalez,Raul; O'Meara,Ciara; Eivers,Bernard; Kelleher,Margaret-M; Evans,Ross-D; Mapel,Xena-M; Lioret-Villas,Audald; Pausch,Hubert; Balas (NATL ACAD SCIENCES, 17/10/2023)
    Despite passing routine laboratory tests for semen quality, bulls used in artificial insemination exhibit significant variation in fertility. Routine analysis of fertility data identified a dairy bull with extreme (10% ...
  • Adiposity assessed close to diagnosis and prostate cancer prognosis in the EPIC study 
    Cariolou,Margarita; Christakoudi,Sofia; Gunter,Marc-J; Key,Tim; Perez-Cornago,Aurora; Travis,Ruth; Zamora-Ros,Raul; Petersen,Kristina-Elin-T; Tjonneland,Anne; Weiderpass,Elisabete; Kaaks,Rudolf; Seibold,Petra; Inan-Eroglu,Elif; Schulze,Matthias-B; Masala, (OXFORD UNIV PRESS, 18/09/2024)
    Background Adiposity has been characterized as a modifiable risk factor for prostate cancer. Its association with outcomes after prostate cancer diagnosis, however, must be better understood, and more evidence is needed ...
  • A Short-Term Altrenogest Treatment Post-weaning Followed by Superovulation Reduces Pregnancy Rates and Embryo Production Efficiency in Multiparous Sows 
    Gonzalez-Ramiro,Henar; Cuello,Cristina; Cambra,Josep-M; Gonzalez-Plaza,Alejandro; Vazquez,Juan-M; Vazquez,Jose-L; Rodriguez-Martinez,Heriberto; Gil,Maria-A; Lucas-Sanchez,Alejandro; Parrilla,Inmaculada; Martinez,Emilio-A (FRONTIERS MEDIA SA, 18/11/2021)
    Simple SummaryStudy comparing the use of a surgical mask, FFP2 or none in people with sarcopenia during a resistance training session on strength performance, heart rate, heart rate variability, blood lactate concentration ...
  • Age and Sex Determine Electrocardiogram Parameters in the Octodon degus 
    Cuenca-Bermejo,Lorena; Fernandez-Del-Palacio,Maria-Josefa; Goncalves,Valeria-de-Cassia; Bautista-Hernandez,Victor; Sanchez-Rodrigo,Consuelo; Fernandez-Villalba,Emiliano; Kublickiene,Karolina; Raparelli,Valeria; Kautzky-Willer,Alexandra; Norris,Colleen-M (MDPI, 19/05/2023)
    Simple SummarySoft tissue sarcomas (STS) are an uncommon and heterogeneous group of tumors, with scarce options for treatment in advanced cases. There is no consensus regarding which is the best treatment sequence for these ...
  • Valoración del maltrato psicológico por su pareja en las mujeres inmigrantes residentes en una zona básica de salud 
    Leal-Hernández, Mariano; Leal-Casas, Lucia; Leal-Casas, Teresa; Pérez-Valencia, Marta; García-Romero, Rocío; Bautista-Martir, Yasmina (Elsevier Doyma, 2020)
  • Melatonin as an Agent for Direct Pulp-Capping Treatment 
    Guerrero-Gironés, Julia; Alcaina-Lorente, Antonia; Ortiz-Ruiz, Clara; Ortiz-Ruiz, Eduardo; Pecci-Lloret, María-P; Rodríguez-Lozano, Francisco-Javier; Martínez, Carlos-M; Ortiz-Ruiz, Antonio-José (MDPI, 2020)
    Melatonin plays an essential role in the regulation of bone growth. The actions that melatonin exerts on odontoblasts may be similar to its action on osteoblasts. This research aimed to evaluate the pulp response to melatonin ...
  • Aortic valve stenosis provides complementary information to bleeding risk scores in non-valvular atrial fibrillation patients initiating anticoagulation 
    Elvira-Ruiz, Gines; Caro-Martínez, Cesar; Flores-Blanco, Pedro-José; Cerezo-Manchado, Juan-José; Albendin-Iglesias, Helena; Lova-Navarro, Alejandro; Arregui-Montoya, Francisco; Muñoz-Franco, Francisca-María; García-Iniesta, Natalia; García-Alberola, Arcadio; Bailén-Lorenzo, José-Luis; Pascual-Figal, Domingo-Andrés; Manzano-Fernández, Sergio (TSINGHUA UNIV PRESS, 2020)
    BACKGROUND: The identification of modifiable bleeding risk factors may be of relevance. The aim is to evaluate if aortic stenosis (AS) provides additional information to bleeding risk scores for predicting major bleeding ...

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