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03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla): Envíos recientes

  • Trends in incidence, mortality and survival in women with breast cancer from 1985 to 2012 in Granada, Spain: a population-based study 
    Baeyens-Fernández, José-Antonio; Molina-Portillo, Elena; Pollán, Marina; Rodríguez-Barranco, Miguel; Del-Moral, Rosario; Arribas-Mir, Lorenzo; Sánchez-Cantalejo-Ramírez, Emilio; Sánchez, María-José (BMC, 2018-08-02)
    BACKGROUND: The incidence of breast cancer has increased since the 1970s. Despite favorable trends in prognosis, the role of changes in clinical practice and the introduction of screening remain controversial. We examined ...
  • Association between plasma phospholipid saturated fatty acids and metabolic markers of lipid, hepatic, inflammation and glycaemic pathways in eight European countries: a cross-sectional analysis in the EPIC-InterAct study 
    Zheng, Ju-Sheng; Sharp, Stephen-J; Imamura, Fumiaki; Koulman, Albert; Schulze, Matthias-B; Ye, Zheng; Griffin, Jules; Guevara, Marcela; Huerta-Castaño, José-María; Kroeger, Janine; Sluijs, Ivonne; Agudo, Antonio; Barricarte, Aurelio; Boeing, Heiner; Colorado-Yohar, Sandra; Dow, Courtney; Dorronsoro, Miren; Dinesen, Pia-T; Fagherazzi, Guy; Franks, Paul-W; Feskens, Edith-J-M; Kuehn, Tilman; Katzke, Verena-Andrea; Key, Timothy-J; Khaw, Kay-Tee; de-Magistris, María-Santucci; Romana-Mancini, Francesca; Molina-Portillo, Elena; Nilsson, Peter-M; Olsen, Anja; Overvad, Kim; Palli, Domenico; Quirós, J-Ramón; Rolandsson, Olov; Ricceri, Fulvio; Spijkerman, Annemieke-M-W; Slimani, Nadia; Tagliabue, Giovanna; Tjonneland, Anne; Tumino, Rosario; van-der-Schouw, Yvonne-T; Langenberg, Claudia; Riboli, Elio; Forouhi, Nita-G; Wareham, Nicholas-J (BMC, 2017-11-17)
    BACKGROUND: Accumulating evidence suggests that individual circulating saturated fatty acids (SFAs) are heterogeneous in their associations with cardio-metabolic diseases, but evidence about associations of SFAs with ...
  • The cross-national epidemiology of social anxiety disorder: Data from the World Mental Health Survey Initiative 
    Stein, Dan-J; Lim, Carmen-C-W; Roest, Annelieke-M; de-Jonge, Peter; Aguilar-Gaxiola, Sergio; Al-Hamzawi, Ali; Alonso, Jordi; Benjet, Corina; Bromet, Evelyn-J; Bruffaerts, Ronny; de-Girolamo, Giovanni; Florescu, Silvia; Gureje, Oye; Haro, Josep-María; Harris, Meredith-G; He, Yanling; Hinkov, Hristo; Horiguchi, Itsuko; Hu, Chiyi; Karam, Aimee; Karam, Elie-G; Lee, Sing; Lepine, Jean-Pierre; Navarro-Mateu, Fernando; Pennell, Beth-Ellen; Piazza, Marina; Posada-Villa, Jose; ten-Have, Margreet; Torres, Yolanda; Viana, María-Carmen; Wojtyniak, Bogdan; Xavier, Miguel; Kessler, Ronald-C; Scott, Kate-M (BMC, 2017-07-31)
    BACKGROUND: There is evidence that social anxiety disorder (SAD) is a prevalent and disabling disorder. However, most of the available data on the epidemiology of this condition originate from high income countries in the ...
  • Manipulation of bicarbonate concentration in sperm capacitation media improvesin vitro fertilisation output in porcine species 
    Soriano-Úbeda, Cristina; Romero-Aguirregomezcorta, Jon; Matas-Parra, Carmen; Visconti, Pablo-E; García-Vázquez, Francisco-Alberto (BMC, 2019-03-11)
    BACKGROUND: The in vivo concentration of bicarbonate (HCO(3) (-)), one of the essential sperm capacitating effectors, varies greatly in the different environments sperm go through from cauda epididymis to the fertilisation ...
  • Pre-diagnostic metabolite concentrations and prostate cancer risk in 1077 cases and 1077 matched controls in the European Prospective Investigation into Cancer and Nutrition 
    Schmidt, Julie-A; Fensom, Georgina-K; Rinaldi, Sabina; Scalbert, Augustin; Appleby, Paul-N; Achaintre, David; Gicquiau, Audrey; Gunter, Marc-J; Ferrari, Pietro; Kaaks, Rudolf; Kuehn, Tilman; Floegel, Anna; Boeing, Heiner; Trichopoulou, Antonia; Lagiou, Pagona; Anifantis, Eleutherios; Agnoli, Claudia; Palli, Domenico; Trevisan, Morena; Tumino, Rosario; Bueno-de-Mesquita, Bas; Agudo, Antonio; Larranaga, Nerea; Redondo-Sánchez, Daniel; Barricarte, Aurelio; Huerta-Castaño, José-María; Quirós, J-Ramón; Wareham, Nick; Khaw, Kay-Tee; Pérez-Cornago, Aurora; Johansson, Mattias; Cross, Amanda-J; Tsilidis, Konstantinos-K; Riboli, Elio; Key, Timothy-J; Travis, Ruth-C (BMC, 2017-07-05)
    BACKGROUND: Little is known about how pre-diagnostic metabolites in blood relate to risk of prostate cancer. We aimed to investigate the prospective association between plasma metabolite concentrations and risk of prostate ...
  • Relationship between the polyp detection rate and the post-colonoscopy colorectal cancer rate 
    Sastre-Lozano, Violeta-María; Morán-Sánchez, Senador; García-Solano, José; Conesa-Zamora, Pablo; Ruiz-Merino, Guadalupe (ARAN EDICIONES, S A, 2019)
  • The ARID1B spectrum in 143 patients: from nonsyndromic intellectual disability to Coffin-Siris syndrome 
    van-der-Sluijs, Pleuntje-J; Jansen, Sandra; Vergano, Samantha-A; Adachi-Fukuda, Miho; Alanay, Yasemin; AlKindy, Adila; Baban, Anwar; Bayat, Allan; Beck-Woedl, Stefanie; Berry, Katherine; Bijlsma, Emilia-K; Bok, Levinus-A; Brouwer, Alwin-F-J; van-der-Burgt, Ineke; Campeau, Philippe-M; Canham, Natalie; Chrzanowska, Krystyna; Chu, Yoyo-W-Y; Chung, Brain-H-Y; Dahan, Karin; De-Rademaeker, Marjan; Destree, Anne; Dudding-Byth, Tracy; Earl, Rachel; Elcioglu, Nursel; Elias, Ellen-R; Fagerberg, Christina; Gardham, Alice; Gener, Blanca; Gerkes, Erica-H; Grasshoff, Ute; van-Haeringen, Arie; Heitink, Karin-R; Herkert, Johanna-C; den-Hollander, Nicolette-S; Horn, Denise; Hunt, David; Kant, Sarina-G; Kato, Mitsuhiro; Kayserili, Hulya; Kersseboom, Rogier; Kilic, Esra; Krajewska-Walasek, Malgorzata; Lammers, Kylin; Laulund, Lone-W; Lederer, Damien; Lees, Melissa; López-González, Vanesa; Maas, Saskia; Mancini, Grazia-M-S; Marcelis, Carlo; Martínez, Francisco; Maystadt, Isabelle; McGuire, Marianne; McKee, Shane; Mehta, Sarju; Metcalfe, Kay; Milunsky, Jeff; Mizuno, Seiji; Moeschler, John-B; Netzer, Christian; Ockeloen, Charlotte-W; Oehl-Jaschkowitz, Barbara; Okamoto, Nobuhiko; Olminkhof, Sharon-N-M; Orellana, Carmen; Pasquier, Laurent; Pottinger, Caroline; Riehmer, Vera; Robertson, Stephen-P; Roifman, Maian; Rooryck, Caroline; Ropers, Fabienne-G; Rosello, Mónica; Ruivenkamp, Claudia-A-L; Sagiroglu, Mahmut-S; Sallevelt, Suzanne-C-E-H; Sanchis-Calvo, Amparo; Simsek-Kiper, Pelin-O; Soares, Gabriela; Solaeche, Lucía; Sonmez, Fatma-Mujgan; Splitt, Miranda; Steenbeek, Duco; Stegmann, Alexander-P-A; Stumpel, Constance-T-R-M; Tanabe, Saori; Uctepe, Eyyup; Utine, G-Eda; Veenstra-Knol, Hermine-E; Venkateswaran, Sunita; Vilain, Catheline; Vincent-Delorme, Catherine; Vulto-van-Silfhout, Anneke-T; Wheeler, Patricia; Wilson, Golder-N; Wilson, Louise-C; Wollnik, Bernd; Kosho, Tomoki; Wieczorek, Dagmar; Eichler, Evan; Pfundt, Rolph; de-Vries, Bert-B-A; Clayton-Smith, Jill; Santen, Gijs-W-E (SPRINGERNATURE, 2019-06)
    PURPOSE: Pathogenic variants in ARID1B are one of the most frequent causes of intellectual disability (ID) as determined by large-scale exome sequencing studies. Most studies published thus far describe clinically diagnosed ...
  • Association of Plasma Vitamin D Metabolites With Incident Type 2 Diabetes: EPIC-InterAct Case-Cohort Study 
    Zheng, Ju-Sheng; Imamura, Fumiaki; Sharp, Stephen-J; van-der-Schouw, Yvonne-T; Sluijs, Ivonne; Gundersen, Thomas-E; Ardanaz, Eva; Boeing, Heiner; Bonet, Catalina; Humberto-Gómez, Jesús; Dow, Courtney; Fagherazzi, Guy; Franks, Paul-W; Jenab, Mazda; Kuehn, Tilman; Kaaks, Rudolf; Key, Timothy-J; Khaw, Kay-Tee; Lasheras, Cristina; Mokoroa, Olatz; Mancini, Francesca-Romana; Nilsson, Peter-M; Overvad, Kim; Panico, Salvatore; Palli, Domenico; Rolandsson, Olov; Sieri, Sabina; Salamanca-Fernández, Elena; Sacerdote, Carlotta; Spijkerman, Annemieke-M-W; Stepien, Magdalena; Tjonneland, Anne; Tumino, Rosario; Butterworth, Adam-S; Riboli, Elio; Danesh, John; Langenberg, Claudia; Forouhi, Nita-G; Wareham, Nicholas-J (ENDOCRINE SOC, 2019-04)
    BACKGROUND: Existing evidence for the prospective association of vitamin D status with type 2 diabetes (T2D) is focused almost exclusively on circulating total 25-hydroxyvitamin D [25(OH)D] without distinction between its ...
  • Predicting Bleeding Events in Anticoagulated Patients With Atrial Fibrillation: A Comparison Between the HAS-BLED and GARFIELD-AF Bleeding Scores 
    Proietti, Marco; Rivera-Caravaca, José-Miguel; Esteve-Pastor, María-Asunción; Romiti, Giulio-Francesco; Marín, Francisco; Lip, Gregory-Y-H (WILEY, 2018-09-18)
    Background Patients with atrial fibrillation (AF) treated with oral anticoagulants may be exposed to an increased risk of bleeding events. The HAS-BLED (Hypertension, Abnormal renal and liver function, Stroke, Bleeding, ...
  • Trauma and PTSD in the WHO World Mental Health Surveys 
    Kessler, Ronald-C; Aguilar-Gaxiola, Sergio; Alonso, Jordi; Benjet, Corina; Bromet, Evelyn-J; Cardoso, Graca; Degenhardt, Louisa; de-Girolamo, Giovanni; Dinolova, Rumyana-V; Ferry, Finola; Florescu, Silvia; Gureje, Oye; Haro, Josep-María; Huang, Yueqin; Karam, Elie-G; Kawakami, Norito; Lee, Sing; Lepine, Jean-Pierre; Levinson, Daphna; Navarro-Mateu, Fernando; Pennell, Beth-Ellen; Piazza, Marina; Posada-Villa, Jose; Scott, Kate-M; Stein, Dan-J; Ten-Have, Margreet; Torres, Yolanda; Viana, María-Carmen; Petukhova, María-V; Sampson, Nancy-A; Zaslavsky, Alan-M; Koenen, Karestan-C (TAYLOR & FRANCIS LTD, 2017)
    Background: Although post-traumatic stress disorder (PTSD) onset-persistence is thought to vary significantly by trauma type, most epidemiological surveys are incapable of assessing this because they evaluate lifetime PTSD ...
  • A FCGR3A Polymorphism Predicts Anti-drug Antibodies in Chronic Inflammatory Bowel Disease Patients Treated With Anti-TNF 
    Romero-Cara, Patricia; Torres-Moreno, Daniel; Pedregosa, Jose; Vílchez, Juan-Antonio; García-Simón, María-Sergia; Ruiz-Merino, Guadalupe; Morán-Sánchez, Senador; Conesa-Zamora, Pablo (IVYSPRING INT PUBL, 2018)
    BACKGROUND: The production of anti-drug antibodies (ADAs) against IgG monoclonal antibodies (mAbs) targeting tumour necrosis factor (TNF) is an important cause of loss of response to anti-TNF mAbs in patients with inflammatory ...
  • In vitro intracellular IFN?, IL-17 and IL-10 producing T cells correlates with the occurrence of post-transplant opportunistic infection in liver and kidney recipients 
    Boix-Giner, Francisco; Llorente-Vinas, Santiago; Eguía, Jorge; González-Martínez, Gema; Alfaro, Rafael; Galián, Jose-A; Campillo, José-Antonio; Moya-Quiles, María-Rosa; Minguela-Puras, Alfredo; Pons-Miñano, José-Antonio; Muro-Pérez, Manuel (BPG, 2018-02-24)
    AIM: To validate intracellular cytokine production functional assay as means of cell-mediated immunity monitoring of post-transplant patients with opportunistic infection (OI). METHODS: Intracellular cytokine-producing ...
  • Alcohol intake in relation to non-fatal and fatal coronary heart disease and stroke: EPIC-CVD case-cohort study 
    Ricci, Cristian; Wood, Ángela; Muller, David; Gunter, Marc-J; Agudo, Antonio; Boeing, Heiner; van-der-Schouw, Yvonne-T; Warnakula, Samantha; Saieva, Calogero; Spijkerman, Annemieke; Sluijs, Ivonne; Tjonneland, Anne; Kyro, Cecilie; Weiderpass, Elisabete; Kuehn, Tilman; Kaaks, Rudolf; Sánchez, María-José; Panico, Salvatore; Agnoli, Claudia; Palli, Domenico; Tumino, Rosario; Engstrom, Gunnar; Melander, Olle; Bonnet, Fabrice; Boer, Jolanda-M-A; Key, Timothy-J; Travis, Ruth-C; Overvad, Kim; Verschuren, W-M-Monique; Quirós, J-Ramón; Trichopoulou, Antonia; Papatesta, Eleni-María; Peppa, Eleni; Moreno-Iribas, Conchi; Gavrila-Chervase, Diana; Forslund, Ann-Sofie; Jansson, Jan-Hakan; Matullo, Giuseppe; Arriola, Larraitz; Freisling, Heinz; Lassale, Camille; Tzoulaki, Ioanna; Sharp, Stephen-J; Forouhi, Nita-G; Langenberg, Claudia; Saracci, Rodolfo; Sweeting, Michael; Brennan, Paul; Butterworth, Adam-S; Riboli, Elio; Wareham, Nick-J; Danesh, John; Ferrari, Pietro (BMJ PUBLISHING GROUP, 2018-05-29)
    OBJECTIVE: To investigate the association between alcohol consumption (at baseline and over lifetime) and non-fatal and fatal coronary heart disease (CHD) and stroke. DESIGN: Multicentre case-cohort study. SETTING: A study ...
  • Childhood adversities and 5-HTTLPR polymorphism as risk factors of substance use disorders: retrospective case-control study in Murcia (Spain) 
    Navarro-Mateu, Fernando; Quesada, Mari-Paz; Escamez, Teresa; Jose-Alcaraz, M; Seiquer-de-la-Pena, Catherine; Salmerón-Martínez, Diego; Huerta-Castaño, José-María; Vilagut, Gemma; Chirlaque-López, María-Dolores; Navarro, Carmen; Husky, Mathilde; Kessler, Ronald-C; Alonso, Jordi; Martínez, Salvador (BMJ PUBLISHING GROUP, 2019-09)
    OBJECTIVE: To explore the separate and joint associations of childhood adversities and 5-HTTLPR polymorphism as risk factors for substance use disorders among adults. : Design : Retrospective case-control study. SETTING: ...
  • Murcia atrial fibrillation project II: protocol for a prospective observational study in patients with atrial fibrillation 
    Rivera-Caravaca, José-Miguel; Marín, Francisco; Esteve-Pastor, María-Asunción; Gálvez, Josefa; Lip, Gregory-Y-H; Vicente, Vicente; Roldan-Schilling, Vanesa (BMJ PUBLISHING GROUP, 2019-12)
    INTRODUCTION: Atrial fibrillation (AF) is characterised by a high stroke risk. Vitamin K antagonists (VKAs) are the most commonly used oral anticoagulants (OACs) in Spain, but their efficacy and safety depend on the time ...
  • Risk factors for mental workload: influence of the working environment, cardiovascular health and lifestyle. A cross-sectional study 
    López-López, María-Luisa; Balanza-Galindo, Serafin; Vera-Catalan, Tomás; Ines-Gallego-Gómez, Juana; Rodríguez-González-Moro, María-Teresa; Rivera-Caravaca, José-Miguel; Simonelli-Muñoz, Agustin-Javier (BMJ PUBLISHING GROUP, 2018-12)
    OBJECTIVES: Mental workload is a condition which can negatively influence the overall health of workers. In this study, we aimed to investigate the risk factors for the onset of mental workload, including working conditions, ...
  • Rationale and design of a multicentre, prospective, randomised, controlled clinical trial to evaluate the efficacy of the adipose graft transposition procedure in patients with a myocardial scar: the AGTP II trial 
    Gastelurrutia, Paloma; Gálvez-Monton, Carolina; Cámara, María-Luisa; Bustamante-Munguira, Juan-Carlos; García-Pavia, Pablo; Avanzas, Pablo; San-Roman, J-Alberto; Pascual-Figal, Domingo-Andrés; de-Teresa, Eduardo; Crespo-Leiro, María-G; Manito, Nicolas; Núñez, Julio; Fernández-Aviles, Francisco; Caballero, Ángel; Teis, Albert; Lupon, Josep; Brugada, Ramon; Martín, Carlos; Silva, Jacob; Revilla-Orodea, Ana; Cánovas-López, Sergio; Melero, Jose-M; Cuenca-Castillo, Jose-J; González-Pinto, Ángel; Bayés-Genís, Antoni (BMJ PUBLISHING GROUP, 2017-08)
    INTRODUCTION: Cardiac adipose tissue is a source of progenitor cells with regenerative capacity. Studies in rodents demonstrated that the intramyocardial delivery of cells derived from this tissue improves cardiac function ...
  • MC1R variants as melanoma risk factors independent of at-risk phenotypic characteristics: a pooled analysis from the M-SKIP project 
    Tagliabue, Elena; Gandini, Sara; Bellocco, Rino; Maisonneuve, Patrick; Newton-Bishop, Julia; Polsky, David; Lazovich, DeAnn; Kanetsky, Peter-A; Ghiorzo, Paola; Gruis, Nelleke-A; Landi, María-Teresa; Menin, Chiara; Fargnoli, María-Concetta; García-Borrón, José-Carlos; Han, Jiali; Little, Julian; Sera, Francesco; Raimondi, Sara (DOVE MEDICAL PRESS LTD, 2018)
    PURPOSE: Melanoma represents an important public health problem, due to its high case-fatality rate. Identification of individuals at high risk would be of major interest to improve early diagnosis and ultimately survival. ...
  • Fatty acid intake in relation to reproductive hormones and testicular volume among young healthy men 
    Mínguez-Alarcon, Lidia; Chavarro, Jorge-E; Mendiola-Olivares, Jaime; Roca, Manuela; Tanrikut, Cigdem; Vioque, Jesús; Jorgensen, Niels; Torres-Cantero, Alberto (WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2017-03)
  • Mesenchymal stromal cell therapy for damaged retinal ganglion cells, is gold all that glitters? 
    Lucas-Ruiz, Fernando; Galindo-Romero, Caridad; García-Bernal, David; Norte-Muñoz, María; Rodríguez-Ramírez, Kristy-T; Salinas-Navarro, Manuel; Millan-Rivero, Jose-E; Vidal-Sanz, Manuel; Agudo-Barriuso, Marta (WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2019-11)

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