Repositorio Dspace

Envíos recientes

03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla): Envíos recientes

  • Prospective evaluation of 92 serum protein biomarkers for early detection of ovarian cancer 
    Mukama, Trasias; Fortner, Renee-Turzanski; Katzke, Verena; Hynes, Lucas-Cory; Petrera, Agnese; Hauck, Stefanie-M; Johnson, Theron; Schulze, Matthias; Schiborn, Catarina; Rostgaard-Hansen, Agnetha-Linn; Tjonneland, Anne; Overvad, Kim; Pérez, María-José-Sánchez; Crous-Bou, Marta; Chirlaque-López, María-Dolores; Amiano, Pilar; Ardanaz, Eva; Watts, Eleanor-L; Travis, Ruth-C; Sacerdote, Carlotta; Grioni, Sara; Masala, Giovanna; Signoriello, Simona; Tumino, Rosario; Gram, Inger-T; Sandanger, Torkjel-M; Sartor, Hanna; Lundin, Eva; Idahl, Annika; Heath, Alicia-K; Dossus, Laure; Weiderpass, Elisabete; Kaaks, Rudolf (SPRINGERNATURE, 2022-05)
    BACKGROUND: CA125 is the best available yet insufficiently sensitive biomarker for early detection of ovarian cancer. There is a need to identify novel biomarkers, which individually or in combination with CA125 can achieve ...
  • Identification of an ASC oligomerization inhibitor for the treatment of inflammatory diseases 
    Soriano-Teruel, Paula-M; García-Lainez, Guillermo; Marco-Salvador, María; Pardo, Julian; Arias, Maykel; DeFord, Christian; Merfort, Irmgard; Vicent, María-J; Pelegrín, Pablo; Sancho, Mónica; Orzaez, Mar (SPRINGERNATURE, 2021-12-13)
    The ASC (apoptosis-associated speck-like protein containing a caspase recruitment domain (CARD)) protein is an scaffold component of different inflammasomes, intracellular multiprotein platforms of the innate immune system ...
  • Growth analysis and blood profile in piglets born by embryo transfer 
    Paris-Oller, Evelyne; Matás, Carmen; Romar, Raquel; Lopes, Jordana-S; Gadea, Joaquín; Cánovas, Sebastián; Coy-Fuster, Pilar (ELSEVIER SCI LTD, 2022-01)
    Assisted reproductive technologies (ART), besides solving several reproductive problems, it has also been used as a tool to improve the animal productivity that is required for feeding the human population. One of these ...
  • Comparison of individual-level and population-level risk factors for rhinoconjunctivitis, asthma, and eczema in the International Study of Asthma and Allergies in Childhood (ISAAC) Phase Three 
    Rutter, Charlotte-E; Silverwood, Richard-J; Asher, MInnes; Ellwood, Philippa; Pearce, Neil; García-Marcos, Luis; Strachan, David-P (ELSEVIER, 2020-06)
    BACKGROUND: Symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema in children cluster at both the individual and population levels. OBJECTIVES: To assess individual-level and school-level risk factors for ...
  • COUPY Coumarins as Novel Mitochondria-Targeted Photodynamic Therapy Anticancer Agents 
    Ortega-Forte, Enrique; Rovira, Anna; Gandioso, Albert; Bonelli, Joaquín; Bosch, Manel; Ruiz, José; Marchan, Vicente (AMER CHEMICAL SOC, 2021-12-09)
    Photodynamic therapy (PDT) for cancer treatment has drawn increased attention over the last decades. Herein, we introduce a novel family of low-molecular-weight coumarins as potential PDT anticancer tools. Through a ...
  • Previous disorders and depression outcomes in individuals with 12-month major depressive disorder in the World Mental Health surveys 
    Roest, Annelieke-M; de-Vries, Ymkje-Anna; Al-Hamzawi, Ali; Alonso, Jordi; Ayinde, Olatunde-O; Bruffaerts, Ronny; Bunting, Brendan; Caldas-de-Almeida, José-Miguel; de-Girolamo, Giovanni; Degenhardt, Louisa; Florescu, Silvia; Gureje, Oye; María-Haro, Josep; Hu, Chiyi; Karam, Elie-G; Kiejna, Andrzej; Kovess-Masfety, Viviane; Lee, Sing; McGrath, John-J; Medina-Mora, María-Elena; Navarro-Mateu, Fernando; Nishi, Daisuke; Piazza, Marina; Posada-Villa, José; Scott, Kate-M; Carlos-Stagnaro, Juan; Stein, Dan-J; Torres, Yolanda; Viana, María-Carmen; Zarkov, Zahari; Kessler, Ronald-C; de-Jonge, Peter (CAMBRIDGE UNIV PRESS, 2021-11)
    AIMS: Major depressive disorder (MDD) is characterised by a recurrent course and high comorbidity rates. A lifespan perspective may therefore provide important information regarding health outcomes. The aim of the present ...
  • Worldwide trends in the burden of asthma symptoms in school-aged children: Global Asthma Network Phase I cross-sectional study 
    Asher, MInnes; Rutter, Charlotte-E; Bissell, K; Chiang, Chen-Yuan; El-Sony, Asma; Ellwood, Eamon; Ellwood, Philippa; García-Marcos, Luis; Marks, Guy-B; Morales, Eva; Mortimer, Kevin; Pérez-Fernández, Virginia; Robertson, Steven; Silverwood, Richard-J; Strachan, David-P; Pearce, Neil (ELSEVIER SCIENCE INC, 2021-10)
    BACKGROUND: Asthma is the most common chronic disease in children globally. The Global Asthma Network (GAN) Phase I study aimed to determine if the worldwide burden of asthma symptoms is changing. METHODS: This updated ...
  • Hematopoietic cell transplantation in severe combined immunodeficiency: The SCETIDE 2006-2014 European cohort 
    Lankester, Arjan-C; Neven, Benedicte; Mahlaoui, Nizar; von-Asmuth, Erik-GJ; Courteille, Virginie; Alligon, Mikael; Albert, Michael-H; Serra, Isabelle-Badell; Bader, Peter; Balashov, Dmitry; Beier, Rita; Bertrand, Yves; Blanche, Stephane; Bordon, Victoria; Bredius, Robbert-G; Cant, Andrew; Cavazzana, Marina; Diaz-de-Heredia, Cristina; Dogu, Figen; Ehlert, Karoline; Entz-Werle, Natacha; Fasth, Anders; Ferrua, Francesca; Ferster, Alina; Formankova, Renata; Friedrich, Wilhelm; González-Vicent, Marta; Gozdzik, Jolanta; Gungor, Tayfun; Hoenig, Manfred; Ikinciogullari, Aydan; Kalwak, Krzysztof; Kansoy, Savas; Kupesiz, Alphan; Lanfranchi, Arnalda; Lindemans, Caroline-A; Meisel, Roland; Michel, Gerard; Miranda, Nuno-AA; Moraleda-Jiménez, José-María; Moshous, Despina; Pichler, Herbert; Rao, Kanchan; Sedlacek, Petr; Slatter, Mary; Soncini, Elena; Speckmann, Carsten; Sundin, Mikael; Toren, Amos; Vettenranta, Kim; Worth, Austen; Yesilipek, Mehmet-A; Zecca, Marco; Porta, Fulvio; Schulz, Ansgar; Veys, Paul; Fischer, Alain; Gennery, Andrew-R (MOSBY-ELSEVIER, 2022-05)
    BACKGROUND: Hematopoietic stem cell transplantation (HSCT) represents a curative treatment for patients with severe combined immunodeficiency (SCID), a group of monogenic immune disorders with an otherwise fatal outcome. ...
  • Prevalence and risk factors associated with allergic rhinitis in Mexican school children: Global Asthma Network Phase I 
    García-Almaraz, Roberto; Reyes-Noriega, Nayely; del-Río-Navarro, Blanca-Estela; Berber, Arturo; Navarrete-Rodríguez, Elsy-Maureen; Ellwood, Philippa; Marcos-Álvarez, Luis-García (ELSEVIER, 2021-01)
    BACKGROUND: The International Study of Asthma and Allergies in Childhood (ISAAC) showed a wide variability in prevalence and severity of allergic rhinitis (AR) and rhinoconjunctivitis (ARC), in addition to other atopic ...
  • Circulating MR-proADM levels, as an indicator of endothelial dysfunction, for early risk stratification of mid-term mortality in COVID-19 patients 
    García-de-Guadiana-Romualdo, Luis; Martínez-Martínez, Mónica; Rodríguez-Mulero, María-Dolores; Esteban-Torrella, Patricia; Hernández-Olivo, Marta; Alcaraz-García, María-José; Campos-Rodríguez, Valerio; Sancho-Rodríguez, Natalia; Galindo-Martínez, María; Alcaraz, Antonia; Ros-Braquehais, María-Salome; Baguena-Pérez-Crespo, Carlos; Ramos-Arenas, Verónica; Tomás-Jiménez, Cristina; Consuegra-Sánchez, Lucíano; Conesa-Hernández, Andrés; Piñera-Salmerón, Pascual; Bernal-Morell, Enrique (ELSEVIER SCI LTD, 2021-10)
    OBJECTIVES: Thromboinflammation, resulting from a complex interaction between thrombocytopathy, coagulopathy, and endotheliopathy, contributes to increased mortality in COVID-19 patients. MR-proADM, as a surrogate of ...
  • Comparative Biological Properties and Mineralization Potential of 3 Endodontic Materials for Vital Pulp Therapy: Theracal PT, Theracal LC, and Biodentine on Human Dental Pulp Stem Cells 
    Luis-Sanz, José; Soler-Doria, Anna; López-García, Sergio; García-Bernal, David; Rodríguez-Lozano, Francisco-J; Lozano, Adrián; Llena, Carmen; Forner, Leopoldo; Guerrero-Gironés, Julia; Melo, María (ELSEVIER SCIENCE INC, 2021-12)
    INTRODUCTION: The aim of this study was to assess the biological properties and mineralization potential of the new Theracal PT (Bisco Inc, Schaumburg, IL) compared with its predecessor Theracal LC (Bisco Inc) and the ...
  • Current status of diagnosis and treatment of heparin-induced thrombocytopenia (HIT) 
    Paramo, José-A; Lozano, María-Luisa; González-Porras, José-Ramon; Mateo, José (ELSEVIER ESPANA SLU, 2022-01-21)
  • Silk fibroin nanoparticles enhance quercetin immunomodulatory properties in DSS-induced mouse colitis 
    Diez-Echave, Patricia; Jesús-Ruiz-Malagón, Antonio; Alberto-Molina-Tijeras, José; Hidalgo-García, Laura; Vezza, Teresa; Cenis-Cifuentes, Laura; Jesús-Rodríguez-Sojo, María; Luis-Cenis, José; Elena-Rodríguez-Cabezas, María; Rodríguez-Nogales, Alba; Galvez, Julio; Abel-Lozano-Pérez, Antonio (ELSEVIER, 2021-09)
    Inflammatory bowel disease (IBD) is a chronic and idiopathic inflammatory disorder affecting the gastrointestinal tract. The pharmacological treatments used currently for its treatment lack efficacy, so new therapeutic ...
  • Y Prospective analysis of circulating metabolites and endometrial cancer risk 
    Dossus, Laure; Kouloura, Eirini; Biessy, Carine; Viallon, Vivian; Siskos, Alexandros-P; Dimou, Niki; Rinaldi, Sabina; Merritt, Melissa-A; Allen, Naomi; Fortner, Renee; Kaaks, Rudolf; Weiderpass, Elisabete; Gram, Inger-T; Rothwell, Joseph-A; Lecuyer, Lucie; Severi, Gianluca; Schulze, Matthias-B; Nost, Therese-Haugdahl; Crous-Bou, Marta; Sánchez, María-José; Amiano, Pilar; Colorado-Yohar, Sandra-M; Gurrea, Aurelio-Barricarte; Schmidt, Julie-A; Palli, Domenico; Agnoli, Claudia; Tumino, Rosario; Sacerdote, Carlotta; Mattiello, Amalia; Vermeulen, Roel; Heath, Alicia-K; Christakoud, Sofía; Tsilidis, Konstantinos-K; Travis, Ruth-C; Gunter, Marc-J; Keun, Hector-C (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2021-08)
    BACKGROUND: Endometrial cancer is strongly associated with obesity and dysregulation of metabolic factors such as estrogen and insulin signaling are causal risk factors for this malignancy. To identify additional novel ...
  • Lenalidomide and dexamethasone with or without clarithromycin in patients with multiple myeloma ineligible for autologous transplant: a randomized trial 
    Puig, Noemi; Hernández, Miguel-T; Rosiñol, Laura; González, Esther; de-Arriba, Felipe; Oriol, Albert; González-Calle, Verónica; Escalante, Fernando; de-la-Rubia, Javier; Gironella, Mercedes; Ríos, Rafael; García-Sánchez, Ricarda; Arguinano, José-M; Alegre, Adrián; Martín, Jesús; Gutiérrez, NormaC; Calasanz, María-J; Martín, María-L; Couto, María-del-Carmen; Casanova, María; Arnao, Mario; Pérez-Persona, Ernesto; Garzon, Sebastián; González, Marta-S; Martín-Sánchez, Guillermo; Ocio, Enrique-M; Coleman, Morton; Encinas, Cristina; Vale, Ana-M; Teruel, Ana-I; Cortes-Rodríguez, María; Paiva, Bruno; Cedena, MTeresa; San-Miguel, Jesús-F; Lahuerta, Juan-J; Blade, Joan; Niesvizky, Rubén; Mateos, María-Victoria (SPRINGERNATURE, 2021-05)
    Although case-control analyses have suggested an additive value with the association of clarithromycin to continuous lenalidomide and dexamethasone (Rd), there are not phase III trials confirming these results. In this ...
  • Impact of an intermittent and localized cooling intervention on skin temperature, sleep quality and energy expenditure in free-living, young, healthy adults 
    Xu, Huiwen; Martínez-Nicolás, Antonio; Martínez-Ávila, Wendy-D; Alcántara, Juan-MA; Corral-Pérez, Juan; Jiménez-Pavon, David; Acosta, Francisco-M; Ruiz, Jonatan-R; Martínez-Tellez, Borja (PERGAMON-ELSEVIER SCIENCE LTD, 2021-04)
    Where people live and work together it is not always possible to modify the ambient temperature; ways must therefore be found that allow individuals to feel thermally comfortable in such settings. The Embr Wave® is a ...
  • Prevalence of asthma symptoms and associated factors in adolescents and adults in southern Brazil: A Global Asthma Network Phase I study 
    Urrutia-Pereira, Marilyn; Chong-Neto, Herberto; Mocellin, Lucas-Pitrez; Ellwood, Philippa; García-Marcos, Luis; Simon, Laura; Rinelli, Pietro; Sole, Dirceu (ELSEVIER, 2021-03)
    BACKGROUND: The Global Asthma Network (GAN) aims to find out the current status of the prevalence and severity of asthma, rhinitis, and eczema using global surveillance to achieve worldwide recognition and improve the ...
  • Genetic determinants of daytime napping and effects on cardiometabolic health 
    Dashti, Hassan-S; Daghlas, Iyas; Lane, Jacqueline-M; Huang, Yunru; Udler, Miriam-S; Wang, Heming; Ollila, Hanna-M; Jones, Samuel-E; Kim, Jaegil; Weedon, Michael-N; Wood, Andrew-R; Aslibekyan, Stella; Garaulet, Marta; Saxena, Richa (NATURE RESEARCH, 2021-02)
    Daytime napping is a common, heritable behavior, but its genetic basis and causal relationship with cardiometabolic health remain unclear. Here, we perform a genome-wide association study of self-reported daytime napping ...
  • Organoplatinum(II) Complexes Self-Assemble and Recognize AT-Rich Duplex DNA Sequences 
    Zamora, Ana; Wachter, Erin; Vera, María; Heidary, David-K; Rodríguez, Venancio; Ortega, Enrique; Fernández-Espín, Vanesa; Janiak, Christoph; Glazer, Edith-C; Barone, Giampaolo; Ruiz, José (AMER CHEMICAL SOC, 2021-02)
    The specific recognition of AT-rich DNA sequences opens up the door to promising diagnostic and/or therapeutic strategies against gene-related diseases. Here, we demonstrate that amphiphilic Pt(II) complexes of the type ...
  • The Role of the Environment in Overweight and Eating Behavior Variability: Insights from a Multivariate Twin Study 
    Herle, Moritz; Madrid-Valero, Juan-J; Morosoli, José-J; Colodro-Conde, Lucía; Ordoñana, Juan-Ramón (CAMBRIDGE UNIV PRESS, 2020-12)
    Research has emphasized the genetic basis of individual differences in body mass index (BMI); however, genetic factors cannot explain the rapid rise of obesity. Eating behaviors have been stipulated to be the behavioral ...

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