Repositorio Dspace

Envíos recientes

03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla): Envíos recientes

  • Reflections on the I-squared index for measuring inconsistency in meta-analysis 
    Higgins, Julian-P-T; López-López, José-Antonio (CAMBRIDGE UNIV PRESS, 2026-05)
    The I-squared index was proposed in 2002 as a measure to help understand the consistency of study results in a meta-analysis. It was developed to overcome some of the limitations of existing measures, principally the ...
  • Objective prediction of siesta based on machine learning and association with obesity 
    Rodríguez-Martin, María; Moreno-Caballero, Fernando; Dashti, Hassan-S; Saxena, Richa; Scheer, Frank-A-J-L; Fernández-Breis, Jesualdo-T; Garaulet, Marta (ELSEVIER, 2026-06)
    OBJECTIVES: To predict siesta behavior using machine learning models trained on self-reported and objective data-temperature (T), activity (A), position (P), and the integrated TAP variable-and to explore its associations ...
  • Quality of information about potentially malignant oral disorders on TikTok: a cross-sectional analysis in the context of social media 
    López-Jornet, Pía; Bennouna, Layla; Parra-Pérez, Francisco; Pons-Fuster, Eduardo (SPRINGER, 2026-05-18)
    OBJECTIVE: Potentially malignant oral disorders (PMODs) can progress to oral cancer, making the quality of available health information especially relevant. This research aimed to analyze TikTok content related to potentially ...
  • Latency following preterm prelabor rupture of membranes before 34 weeks of gestation and its association with perinatal outcomes: a retrospective cohort study 
    López-Martínez, Pilar; Sánchez-Romero, Javier; Muñoz-Porcel, Rosa; Mokachir-Mohsenin, Zoraya; Blanco-Carnero, José-Eliseo; Crespo-Bañón, Paz; Liandro, Romina-Sol; Hernández-Hernández, Laura; Dagklis, Themistoklis; Nieto-Díaz, Aníbal; de-Paco-Matallana, Catalina (SPRINGER HEIDELBERG, 2026-05-16)
    PURPOSE: To evaluate the association between latency duration and perinatal outcomes in pregnancies complicated by preterm prelabor rupture of membranes (PPROM) before 34 weeks of gestation, and to assess the role of ...
  • Comparison of Three Devices Preventing Skin Damage During Facial Mask Ventilation in Acute Respiratory Failure: Multicenter Randomized Controlled Trial Protocol (3PROSNIVtrial) 
    Scala, Raffaele; Andolfi, Federica; Ottaviano, Giulia; Renda, Teresa; Ceparano, Elena; Caneschi, Manuela; Guidelli, Luca; Vega, María-Laura; Pisani, Lara; Bassi, Ilaria; Aprile, Alfredo; Bertini, Stefania; Bonanni, Daniela; Zoccali, Patrizia; Vitacca, Michele; Barbano, Luca; Torrano-Ferrandez, María; Rozua-López, Ana; Ruiz-Villa, Genoveva; Marchese, Santino-A; Lo-Grasso, Geraldine; Fiandra, Elisabetta; Scoscia, Elvio; Eslami, Amir; Albo, Emanuela; Baglioni, Stefano; Facciolongo, Nicola; Castagnetti, Claudia; Barbieri, Chiara; Boccafoglio, Fabio; Viola, Sonia; Esquinas-Rodríguez, Antonio (SPRINGERNATURE, 2026-06)
    BACKGROUND: In patients with acute respiratory failure (ARF) undergoing noninvasive ventilation (NIV), pressure-related skin injury is among the most frequent and clinically relevant complications. The reported prevalence ...
  • Rituximab and IVIG added to plasma exchange improves the outcome of severe CNS demyelinating attacks: a retrospective study 
    Chico-García, Juan-Luis; Morales-de-la-Prida, Moisés; Boix-Lago, Almudena; García-Domínguez, José-Manuel; Sepulveda, María; Martínez-Hernández, Eugenia; Guasp, Mar; Fonseca, Elianet; Calvi, Alberto; Alba-Isasi, María-Teresa; Alberti, Blanca; Cid, Joan; Lozano, Miquel; Charry, Paola; Rodríguez-Jorge, Fernando; Sainz-Amo, Raquel; Sainz-de-la-Maza, Susana; Monreal, Enric; Villar, Luisa-María; Masjuan, Jaime; Valero-López, Gabriel; Millán-Pascual, Jorge; Cuello, Juan-Pablo; Palacios, Michael; Gifreu-Fraixino, Ariadna; Martínez-Gins, María-Luisa; Álvarez-Bravo, Gary; Meca-Lallana, José-Eustasio; Costa-Frossard, Lucienne; Blanco, Yolanda; Cabrera-Maqueda, José-María; Saiz, Albert; Llufriu, Sara (SAGE PUBLICATIONS LTD, 2026-05)
    BACKGROUND: Plasma exchange (PE) is a therapeutic option for CNS demyelinating attacks unresponsive to corticosteroids, but the potential benefit of adding rituximab and IV immunoglobulins to PE (RTX-IVIG-PE), which has ...
  • Meta-regression with categorical moderators and dependent effect sizes: A simulation study 
    Fernández-Castilla, Belén; López-López, José-Antonio; Rubio-Aparicio, María (CAMBRIDGE UNIV PRESS, 2026-05-14)
    Categorical moderators are often found in meta-analysis and examined using meta-regression models. When multiple effect sizes are present within studies, several methods can be used for meta-regression: multivariate models, ...
  • Circulating fatty acid binding protein 4 (FABP-4) concentrations and mortality in individuals with colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study 
    Pham, Thu-Thi; Nimptsch, Katharina; Aleksandrova, Krasimira; Jenab, Mazda; Fedirko, Veronika; Olsen, Anja; Tjonneland, Anne; Cadeau, Claire; Severi, Gianluca; Schulze, Matthias-B; Fortner, Renee-Turzanski; Katzke, Verena; Agnoli, Claudia; Sacerdote, Carlotta; Tumino, Rosario; Signoriello, Simona; Trobajo-Sanmartin, Camino; Gómez-Gómez, Jesús-Humberto; Chirlaque-López, María-Dolores; Sánchez, María-José; Crous-Bou, Marta; May, Anne; Heath, Alicia; Aune, Dagfinn; Weiderpass, Elisabete; Pischon, Tobias (WILEY, 2026-02)
    Human fatty acid binding protein-4 (FABP-4), a protein elevated in obesity that promotes colon cancer cell invasiveness and metastasis, may be associated with higher mortality in individuals with colorectal cancer (CRC) ...
  • Environmental risk factors for allergic rhinitis differ by income level: A Global Asthma Network survey 
    Masekela, Refiloe; Rutter, Charlotte-E; Mortimer, Kevin; Chiang, Chen-Yuan; García-Marcos, Luis; El-Sony, Asma; Bissell, Karen; Ellwood, Eamon; Pearce, Neil; Asher, Innes; Ellwood, Phillipa; Singh, Nishtha; Khumalo, Anele; Morales, Eva (WILEY, 2026-04)
    BACKGROUND: Estimating the prevalence and identifying risk factors for allergic rhinitis (AR) provides critical burden of disease data and offers opportunity to intervene in early-life preventing morbidity. METHODS: We ...
  • Rehabilitation interventions in bronchiectasis: expanding evidence, personalization, and clinical practice 
    Esquinas-Rodríguez, Antonio; Guimaraes, Fernando-Silva (FRONTIERS MEDIA SA, 2026-03-25)
    Bronchiectasis is a chronic and heterogeneous respiratory disease characterized by irreversible airway dilation, recurrent infection, persistent inflammation, and progressive functional impairment. Pulmonary rehabilitation ...
  • Vitamin D in the prevention of left ventricular remodelling after an acute myocardial infarction: a randomized clinical trial 
    Tunon, José; Rodríguez-López, Carlos; Balaguer, Jorge; Gómez-Talavera, Sandra; Rojas, Antonio; Salamanca, Jorge; López-García, Cecilia; Esteve-Pastor, María-Asunción; Laffond, Ana; Herrera, Cristian; Escudier-Villa, Juan-M; Orejas, Miguel; Tomas, Marta; López-Álvarez, María; Arcas-Tomeo, Mireia; Llanos-Jiménez, Lucía; González-Lorenzo, Óscar; Kallmeyer, Andrea; Ibáñez, Borja; González-Casaus, María-Luisa; Hernández, Gonzalo; Espadas, Cristina; Lorenzo, Óscar; Mahillo-Fernández, Ignacio; Egido, Jesús; Sánchez, Pedro-Luis; Marín, Francisco; Alfonso, Fernando (SPRINGERNATURE, 2026-04-06)
    No clinical trial has yet assessed the effect of vitamin D on patients experiencing ST-segment elevation myocardial infarction (STEMI). In this multicentre, randomised (2:1), double-blind, placebo-controlled trial, 93 ...
  • Durvalumab plus tremelimumab for the treatment of patients with progressive, refractory advanced thyroid carcinoma: the phase II GETNE-DUTHY trial 
    Capdevila, Jaume; Hernando, Jorge; Molina-Cerillo, Javier; Plana-Serrahima, María; Taberna-Sanz, Miren; Castelo, Beatriz; Álvarez-Escola, Cristina; Carmona-Bayonas, Alberto; Ballester-Navarro, Inmaculada; Iglesias, Lara; Bover, Mateo; García-Álvarez, Alejandro; Lavernia, Javier; Yaya-Tur, Ricardo; Ruiz, Sofía; Baste, Neus; Lorenzo-Lorenzo, Isabel; Sánchez-Hernández, Alfredo; Sanz-García, Enrique; Marquina, Gloria; Nuciforo, Paolo; Elguero, Belén; Grande, Enrique; Alonso-Gordoa, Teresa (SPRINGERNATURE, 2026-04-04)
    Single-agent PD-1 blockade demonstrated promising efficacy in advanced thyroid cancer. The phase II, single-arm, multi-cohort GETNE-DUTHY trial (clinicaltrials.gov NCT03753919, EudraCT 2018-001066-42) aimed to determine ...
  • Optimal nap timing and body mass index: beyond duration 
    Longo-Silva, Giovana; Rodríguez-Martin, María; Salmerón-Martínez, Diego; Scheer, Frank-A-J-L; Garaulet, Marta (SPRINGER, 2026-04-01)
    BACKGROUND: Overweight and obesity continue to rise globally, and sleep has emerged as an important behavioral determinant of body weight. While nighttime sleep has been widely studied, the role of daytime napping-especially ...
  • Quality of life, care needs and priorities in atrial fibrillation: the impact of number and patterns of comorbidities 
    Trevisan, Caterina; Ravelli, Adele; Rivera-Caravaca, José-Miguel; Zanforlini, Bruno-Micael; Sergi, Giuseppe; Dan, Gheorghe-Andrei; Dan, Anca-Rodica; Roldán-Schilling, Vanessa; Marín-Ortuno, Francisco; Johnsen, Soren-Paaske; Petrovic, Mirko; Vetrano, Davide-Liborio; Leo, Donato-Giuseppe; Lane, Deirdre-A (SPRINGER, 2026-05)
    PURPOSE: Atrial fibrillation (AF) often coexists with multiple chronic conditions, worsening health-related quality of life (HRQoL) and increasing the burden on patients and caregivers. While multimorbidity is known to ...
  • Comparative effectiveness of anti-CD20 therapies and S1P receptor modulators in late-onset multiple sclerosis: real-world evidence from the MSBase registry 
    Surcinelli, Andrea; Kalincik, Tomas; Roos, Izanne; D'amico, Emanuele; Lechner-Scott, Jeannette; Ozakbas, Serkan; Hradilek, Pavel; Horakova, Dana; Vachova, Marta; Panzera, Ivan; Ruzza, Stefano; Piscaglia, María-Grazia; Gerlach, Oliver; Meca-Lallana, José-Eustasio; Valero-López, Gabriel; Kermode, Allan-G; Fabis-Pedrini, Marzena-J; Prevost, Julie; Ampapa, Radek; Hodgkinson, Suzanne; Grand'maison, Francois; Khoury, Samia-J; John, Nevin-A; Peterka, Marek; Houskova, Jana; Recmanova, Eva; Rous, Zuzana; Shaygannejad, Vahid; Alroughani, Raed; Kuhle, Jens; Jakob, Gregor-Brecl; Grammond, Pierre; Patti, Francesco; Van-Der-Walt, Anneke; Butzkueven, Helmut; Foschi, Matteo (SAGE PUBLICATIONS LTD, 2026-03)
    BACKGROUND: Late-onset multiple sclerosis (LOMS), defined by symptom onset after age 50, is increasingly recognised as a distinct clinical entity. Evidence comparing disease-modifying therapies (DMTs) in this subgroup ...
  • Immune mechanisms driving clinical heterogeneity in oral lichen planus 
    Pons-Fuster, Eduardo; Conesa-Solano, Julia; Gimeno-Arias, Lourdes; Martí-de-Gea, Keren; Alguazas, Inmaculada; Ruiz-Lorente, Inmaculada; Minguela-Puras, Alfredo; López-Jornet, Pía (SPRINGERNATURE, 2026-03-31)
    Oral lichen planus (OLP) is a clinically localized mucosal disease that nonetheless exhibits systemic immune alterations contributing to its heterogeneous presentations. This study investigated systemic immunological ...
  • The Murcia Twin Registry: 20 Years of Study and Progress in Health and Behavioral Traits in Spain 
    Sánchez-Romera, Juan-F; Blanco-García, Federico-J; Carrillo-Verdejo, Eduvigis; Colodro-Conde, Lucía; González-Javier, Francisca; Madrid-Valero, Juan-José; Martínez-Selva, José-María; Monteagudo-Piqueras, Olga; Morosoli, José-J; Ordoñana, Juan-Ramón (CAMBRIDGE UNIV PRESS, 2026-03-31)
    The Murcia Twin Registry (MTR) has steadily expanded over two decades and has become a key resource for twin research in the Mediterranean region. The registry currently includes data from 3971 individual twins born between ...
  • Identification of a robust metabolic signature associated with hospital-acquired pneumonia and response to interferon-gamma treatment in critically ill patients 
    Petrier, Melanie; Sinha, Debajyoti; Martín, Florian-P; Poulain, Cecile; Duchaussoy, Delphine-Flattres; Ziogas, Athanasios; Novakovic, Boris; Hurtado-Navarro, Laura; Ferreira, Anaisa; Martens, Joost-H-A; Koulenti, Despoina; Fernández-Barat, Laia; Torres, Antoni; Montassier, Emmanuel; Netea, Mihai-G; Poschmann, Jeremie; Roquilly, Antoine (SPRINGER, 2026-03-12)
    AIM: Our objective was to increase our understanding of the effects of the time course of metabolic alterations on the risk of hospital-acquired pneumonia (HAP) and response to treatment in critically ill patients. METHODS: ...
  • Interventional strategies to address burnout in young medical oncologists: results from the Resilience-Spanish Society of Medical Oncology (SEOM) Study and a university hospital experience in Spain 
    Pacheco-Barcia, Vilma; Obispo, Berta; Tomas, Elia; Salva-de-Torres, Clara; Quintanar, Teresa; Paez, David; León-Mateos, Luis; Cancio, Hernan; Cortegoso, Alexandra; Anido, Urbano; Quilez, Alicia; Tarazona, Noelia; Jiménez-Labaig, Pablo; Sánchez-Martínez, Domingo-Antonio; Sesma-Goni, Andrea; Fernández-Montes, Ana; Felip, Enriqueta; Rodríguez, César; Elez, Elena (SPRINGER INT PUBL AG, 2025-12-23)
    PURPOSE: Burnout syndrome is an increasingly prevalent problem among young oncologists with a prevalence of up to 71% of physicians in Europe, with potential personal and professional consequences. Few studies have been ...
  • Dietary nitrosyl-heme from processed meats and its association with colorectal cancer risk: findings from the EPIC cohort study 
    Rizzolo-Brime, Lucía; Lujan-Barroso, Leila; Farran-Codina, Andreu; Bou, Ricard; Nicolas, Genevieve; Huybrechts, Inge; Lasheras, Cristina; Molina-Montes, Esther; Colorado-Yohar, Sandra; Gasque, Alba; Dahm, Christina-C; Bock, Niels; Olsen, Anja; Tjonneland, Anne; Katzke, Verena; Le-Cornet, Charlotte; Schulze, Matthias-B; Saieva, Calogero; Sieri, Sabina; de-Magistris, María-Santucci; Tumino, Rosario; Macciotta, Alessandra; Wareham, Nick; Weiderpass, Elisabete; Chatziioannou, Chrysovalantou; Vineis, Paolo; Jakszyn, Paula (SPRINGER, 2025-12-20)
    BACKGROUND: Processed meat (PM) consumption is an established risk factor for colorectal cancer (CRC). It has been hypothesized that nitrosyl-heme, formed by the addition of nitrites during meat processing, may enhance the ...

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