Repositorio Dspace

Envíos recientes

03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla): Envíos recientes

  • Lifestyle changes and postmenopausal breast cancer risk in women from the European Prospective Investigation into Cancer and Nutrition 
    Vasson, Fanelie; Matta, Komodo; Biessy, Carine; S-Antoniussen, Christian; Fournier, Agnes; Marques, Chloe; Cadeau, Claire; Le-Cornet, Charlotte; T-Fortner, Renee; Schulze, Matthias-B; Sieri, Sabina; Panico, Salvatore; Tumino, Rosario; Ricceri, Fulvio; Masala, Giovanna; Hiensch, Anouk-E; Monninkhof, Evelyn-M; Agudo, Antonio; Guevara, Marcela; Colorado-Yohar, Sandra; Sánchez, María-José; Llorente, Adrián; Tin-Tin, Sandar; Jackson, Isobel-G; Gunter, Marc-J; Botteri, Edoardo; Ferrari, Pietro; Dossus, Laure (BMC, 2025-10-29)
    BACKGROUND: The risk of breast cancer has been associated with various lifestyle factors, yet the evidence regarding how lifestyle modifications affect this risk remains limited. This study examines the relationship between ...
  • Evaluating the effect of heart and respiratory rate measurement errors on the ability to predict the outcome of high flow nasal cannula therapy: a multi-centre study 
    Yu, Hang; Saffaran, Sina; Tonelli, Roberto; Laffey, John-G; Zhang, Qingchen; Esquinas-Rodríguez, Antonio; Martins-de-Lima, Lucas; Kawano-Dourado, Leticia; Maia, Israel-S; Cavalcanti, Alexandre-Biasi; Clini, Enrico; Bates, Declan-G (BMC, 2025-11-22)
    BACKGROUND: The respiratory rate oxygenation (ROX) index, and machine learning (ML) models, are promising approaches to help clinicians identify earlier those patients at risk of failing high flow nasal cannula (HFNC) ...
  • CAR-T cells targeting CCR9 and CD1a for the treatment of T cell acute lymphoblastic leukemia 
    Tirado, Nestor; Fidyt, Klaudyna; Mansilla, María-José; García-Pérez, Alba-María; Martínez-Moreno, Alba; Vinyoles, Meritxell; Alcain, Juan; García-Peydro, Marina; Roca-Ho, Heleia; Fernández-Fuentes, Narcis; Guerrero-Murillo, Mercedes; Falgas, Aida; Velasco-Hernández, Talia; Bueno, Clara; Panelli, Patrizio; Mulens-Arias, Vladimir; Apostolov, Apostol; Engel, Pablo; González-Navarro, Europa-Azucena; Vick, Binje; Jeremias, Irmela; Caye-Eude, Aurelie; Baruchel, Andre; Cave, Helene; Genesca, Eulalia; Ribera, Jordi; Díaz-Beya, Marina; Martínez-Sánchez, María-Victoria; Fuster-Soler, José-Luis; Escudero-López, Adela; Minguillon, Jordi; Pérez-Martínez, Antonio; Ramírez-Orellana, Manuel; Torrebadell, Montserrat; Díaz, Víctor-M; Toribio, María-L; Sánchez-Martínez, Diego; Menéndez, Pablo (BMC, 2025-07-01)
    T cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignancy characterized by high rates of induction failure and relapse, and effective targeted immunotherapies are lacking. Despite promising clinical progress ...
  • Predictors and barriers to minimally adequate treatment among treated individuals with mental disorders: results from the World Mental Health Surveys. 
    Pozuelo, Julia-R; Vigo, Daniel-V; Kazdin, Alan-E; Harris, Meredith-G; Stein, Dan-J; Viana-Llamas, María-Carmen; Hwang, Irving; Kessler, Timothy-L; Manoukian, Sophie-M; Sampson, Nancy-A; Aguilar-Gaxiola, Sergio; Alonso, Jordi; Andrade, Laura-Helena; Ayinde, Olatunde-O; Bruffaerts, Ronny; Bunting, Brendan; Caldas-de-Almeida, José-Miguel; Chardoul, Stephanie; de-Girolamo, Giovanni; Domenech, Cristina; Gureje, Oye; Karam, Elie-G; Kiejna, Andrzej; Kovess-Masfety, Viviane; Medina-Mora, María-Elena; Moskalewicz, Jacek; Navarro-Mateu, Fernando; Nishi, Daisuke; Piazza, Marina; Posada-Villa, José; Scott, Kate-M; Ten-Have, Margreet; Torres, Yolanda; Vladescu, Cristian; Kessler, Ronald-C (BMC, 2025-12-18)
    BACKGROUND: Treatments for mental disorders vary widely in type and quality, with many patients failing to receive treatments that meet even minimally adequate standards. We use data from the World Mental Health (WMH) ...
  • Pathway to effective treatment for common mental and substance use disorders in the World Mental Health Surveys: Perceived need for treatment 
    Harris, Meredith-G; Kazdin, Alan-E; Hwang, Irving; Manoukian, Sophie-M; Sampson, Nancy-A; Stein, Dan-J; Viana-Llamas, María-Carmen; Vigo, Daniel-V; Alonso, Jordi; Andrade, Laura-Helena; Bruffaerts, Ronny; Bunting, Brendan; Caldas-de-Almeida, José-Miguel; Chardoul, Stephanie; de-Girolamo, Giovanni; Gureje, Oye; Haro, Josep-María; Karam, Elie-G; Kovess-Masfety, Viviane; Medina-Mora, María-Elena; Navarro-Mateu, Fernando; Nishi, Daisuke; Posada-Villa, José; Rapsey, Charlene; Stagnaro, Juan-Carlos; ten-Have, Margreet; Wciorka, Jacek; Zarkov, Zahari; Kessler, Ronald-C (BMC, 2025-05-23)
    BACKGROUND: Perceived need for treatment is a first step along the pathway to effective mental health treatment. Perceived need encompasses a person's recognition that they have a problem and their belief that professional ...
  • Patterns and predictors of 12-month treatment of common anxiety, mood, and substance use disorders in the World Mental Health (WMH) surveys: treatment in the context of perceived need 
    Stein, Dan-J; Vigo, Daniel-V; Harris, Meredith-G; Kazdin, Alan-E; Viana-Llamas, María-Carmen; Hwang, Irving; Kessler, Timothy-L; Manoukian, Sophie-M; Sampson, Nancy-A; Alonso, Jordi; Andrade, Laura-Helena; Benjet, Corina; Bruffaerts, Ronny; Bunting, Brendan; Cardoso, Graca; Chardoul, Stephanie; de-Girolamo, Giovanni; de-Jonge, Peter; Gureje, Oye; Haro, Josep-María; Karam, Elie-G; Kovess-Masfety, Viviane; Moskalewicz, Jacek; Navarro-Mateu, Fernando; Nishi, Daisuke; Posada-Villa, José; Scott, Kate; Stagnaro, Juan-Carlos; Vladescu, Cristian; Wciorka, Jacek; Zarkov, Zahari; Kessler, Ronald-C; Aguilar-Gaxiola, Sergio; Al-Hamzawi, Ali; Altwaijri, Yasmin-A; Atwoli, Lukoye; Borges, Guilherme; Bromet, Evelyn-J; Caldas-de-Almeida, José-Miguel; Cia, Alfredo-H; Degenhardt, Louisa; de-Guzmán, Ma-Lourdes-Rosanna-E; Hinkov, Hristo; Hu, Chi-yi; Karam, Aimee-Nasser; Karam, Georges; Kawakami, Norito; Khaled, Salma; Kiejna, Andrzej; Mcgrath, John-J; Medina-Mora, María-Elena; Piazza, Marina; Scott, Kate-M; ten-Have, Margreet; Torres, Yolanda; Williams, David-R; Wojtyniak, Bogdan; Woodruff, Peter; Xavier, Miguel; Zaslavsky, Alan-M (BMC, 2025-03-14)
    BACKGROUND: Data from the World Mental Health (WMH) surveys on the coverage cascade has underscored the importance of perceived need for seeking treatment of mental disorders. However, little research has focused on treatment ...
  • Barriers to 12-month treatment of common anxiety, mood, and substance use disorders in the World Mental Health (WMH) surveys 
    Viana-Llamas, María-Carmen; Kazdin, Alan-E; Harris, Meredith-G; Stein, Dan-J; Vigo, Daniel-V; Hwang, Irving; Manoukian, Sophie-M; Sampson, Nancy-A; Alonso, Jordi; Andrade, Laura-Helena; Borges, Guilherme; Bunting, Brendan; Caldas-de-Almeida, José-Miguel; de-Girolamo, Giovanni; de-Jonge, Peter; Gureje, Oye; Haro, Josep-María; Karam, Elie-G; Kovess-Masfety, Viviane; Moskalewicz, Jacek; Navarro-Mateu, Fernando; Nishi, Daisuke; Piazza, Marina; Posada-Villa, José; Scott, Kate-M; Vladescu, Cristian; Wojtyniak, Bogdan; Zarkov, Zahari; Kessler, Ronald-C; Kessler, Timothy; World-Mental-Hlth-Survey-collaborators, Sergio (BMC, 2025-02-09)
    BACKGROUND: High unmet need for treatment of mental disorders exists throughout the world. An understanding of barriers to treatment is needed to develop effective programs to address this problem. METHODS: Data on barriers ...
  • Recommendations for management of infants and young children with achondroplasia: Does clinical practice align? 
    Guillén-Navarro, Encarna; Alsayed, Moeenaldeen; Alves, Inés; Ben-Omran, Tawfeg; Boero, Silvio; Cormier-Daire, Valerie; Fauroux, Brigitte; Fredwall, Svein; Irving, Melita; Kunkel, Philip; Lampe, Christian; Lausch, Ekkehart; Maghnie, Mohamad; Mohnike, Klaus; Mortier, Geert; Pejin, Zagorka; Sessa, Marco; Sousa, Sergio-B (BMC, 2025-03-11)
    BACKGROUND: Achondroplasia is one of the most prevalent forms of skeletal dysplasia. Lifelong follow-up by an experienced multidisciplinary team is required, particularly during the first 2 years. In 2021, international ...
  • Regulation of glial markers expression in the rat basolateral amygdala and hippocampus during morphine aversive memory retrieval and its extinction 
    Franco-García, Aurelio; Gómez-Murcia, Victoria; Nuñez, Cristina (BMC, 2025-12-14)
    BACKGROUND: Opioid use disorder is driven by neurobehavioral adaptations where environmental cues trigger relapse. Consequently, extinction therapy (ET) aims to modify drug-associated memories but has limited long-term ...
  • ApoJ and apoL1 as novel determinants of MASH: a cross-sectional study 
    Cai, Zichun; Najib, Souad; Núñez-Sánchez, María-Ángeles; Martínez-Sánchez, María-A; García-Melgares-Gil, Carmen; Viguerie, Nathalie; Rossell, Joana; Julve, Josep; Croyal, Mikael; Rodrigues-Oliveira, Arsenio; Martínez, Carlos-M; Dumas, Sebastien-J; Genoux, Annelise; Frutos-Bernal, María-Dolores; Ramos-Molina, Bruno; Martínez, Laurent-O (BMC, 2025-10-14)
    BACKGROUND: Plasma apolipoproteins are linked to cardiometabolic dysfunctions, but their potential as biomarkers for metabolic dysfunction-associated steatohepatitis (MASH) remains underexplored. METHODS: Plasma levels of ...
  • Dietary nitrosyl-heme from processed meats and its association with colorectal cancer risk: findings from the EPIC cohort study 
    Rizzolo-Brime, Lucía; Luján-Barroso, Leila; Farran-Codina, Andreu; Bou, Ricard; Nicolás, Genevieve; Huybrechts, Inge; Lasheras, Cristina; Molina-Montes, Esther; Colorado-Yohar, Sandra; Gasque, Alba; Dahm, Christina-C; Bock, Niels; Olsen, Anja; Tjonneland, Anne; Katzke, Verena; Le-Cornet, Charlotte; Schulze, Matthias-B; Saieva, Calogero; Sieri, Sabina; De-Magistris, María-Santucci; Tumino, Rosario; Macciotta, Alessandra; Wareham, Nick; Weiderpass, Elisabete; Chatziioannou, Chrysovalantou; Vineis, Paolo; Jakszyn, Paula (BMC, 2025-12-20)
    BACKGROUND: Processed meat (PM) consumption is an established risk factor for colorectal cancer (CRC). It has been hypothesized that nitrosyl-heme, formed by the addition of nitrites during meat processing, may enhance the ...
  • Relation of the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio to residual risk in anticoagulated patients with atrial fibrillation: a report from the prospective Murcia AF Project III cohort 
    Soler-Espejo, Eva; Chen, Yang; Rivera-Caravaca, José-Miguel; Ramos-Bratos, María-Pilar; Esteve-Pastor, María-Asunción; Marín, Francisco; Roldan-Schilling, Vanesa; Lip, Gregory-Y-H (BMC, 2025-09-30)
    BACKGROUND: Atrial fibrillation (AF) confers a high risk of thromboembolism and cardiovascular events, which persists despite optimal oral anticoagulation (OAC). The non-high-density lipoprotein cholesterol (non-HDL-C) to ...
  • Remnant-to-LDL cholesterol discordance as a predictor of thromboembolic events in anticoagulated patients with atrial fibrillation: a report from the prospective Murcia AF project III (MAFP-III) cohort study 
    Soler-Espejo, Eva; Chen, Yang; Rivera-Caravaca, José-Miguel; Ramos-Bratos, María-Pilar; López-Gálvez, Raquel; Marín, Francisco; Roldan-Schilling, Vanesa; Lip, Gregory-Y-H (BMC, 2025-07-10)
    BACKGROUND: Remnant cholesterol (RC) has emerged as an independent contributor to residual cardiovascular risk, beyond low-density lipoprotein cholesterol (LDL-C). As atrial fibrillation (AF) is a common arrhythmia associated ...
  • The triglyceride-glucose index, a marker of insulin resistance, as a predictor of thrombotic risk in atrial fibrillation 
    Rivera-Caravaca, José-Miguel; Soler-Espejo, Eva; Ramos-Bratos, María-Pilar; López-Gálvez, Raquel; González-Lozano, Eduardo; Lip, Gregory-Y-H; Marín, Francisco; Roldan-Schilling, Vanesa (BMC, 2025-07-10)
    BACKGROUND: Atrial fibrillation (AF) increases the risk of stroke making accurate risk stratification central for effective management. The triglyceride-glucose (TyG) index, a marker of insulin resistance, has been associated ...
  • Obsessive-compulsive disorder in the World Mental Health surveys 
    Stein, Dan-J; Ruscio, Ayelet-Meron; Altwaijri, Yasmin; Chiu, Wai-Tat; Sampson, Nancy-A; Aguilar-Gaxiola, Sergio; Al-Hamzawi, Ali; Alonso, Jordi; Chardoul, Stephanie; Gureje, Oye; Hu, Chiyi; Karam, Elie-G; Mcgrath, John-J; Navarro-Mateu, Fernando; Scott, Kate-M; Stagnaro, Juan-Carlos; Torres, Yolanda; Vladescu, Cristian; Wciorka, Jacek; Xavier, Miguel; Kessler, Ronald-C (BMC, 2025-07-09)
    BACKGROUND: National surveys have suggested that obsessive-compulsive disorder (OCD) is a prevalent and impairing condition. However, there are few cross-national data on OCD, with data particularly scarce in low- and ...
  • Nut consumption, linoleic and ?-linolenic acid intakes, and genetics: how fatty acid desaturase 1 impacts plasma fatty acids and type 2 diabetes risk in EPIC-InterAct and PREDIMED studies 
    Jaeger, Susanne; Kuxhaus, Olga; Prada, Marcela; Huybrechts, Inge; Tong, Tammy-Y-N; Forouhi, Nita-G; Razquin, Cristina; Corella, Dolores; Martínez-González, Miguel-A; Dahm, Christina-C; Ibsen, Daniel-B; Tjonneland, Anne; Halkjaer, Jytte; Marques, Chloe; Cadeau, Claire; Ren, Xuan; Katzke, Verena; Bendinelli, Benedetta; Agnoli, Claudia; Catalano, Alberto; Farras, Marta; Sánchez, María-José; Chirlaque-López, María-Dolores; Guevara, Marcela; Aune, Dagfinn; Sharp, Stephen-J; Wareham, Nicholas-J; Schulze, Matthias-B (BMC, 2025-06-09)
    BACKGROUND: Dietary guidelines recommend replacing saturated fatty acid with unsaturated fats, particularly polyunsaturated fatty acids. Cohort studies do not suggest a clear benefit of higher intake of polyunsaturated ...
  • Economic burden of secondary progressive multiple sclerosis: DISCOVER study 
    Oreja-Guevara, Celia; Meca-Lallana, José-Eustasio; Gómez-Estevez, Irene; Ara, José-Ramón; Hernández-Pérez, Miguel-Ángel; Gil, Julia-Gracia; Alonso-Torres, Ana-María; Pilo-de-la-Fuente, Belén; Ramio-Torrenta, Lluis; Eichau-Madueño, Sara; Gascon-Giménez, Francisco; Casanova, Bonaventura; Martínez-Yelamos, Sergio; Aguado-Valcárcel, Marta; Martínez-Gines, María-Luisa; Montero, Yasmina-El-Berdei; López-Real, Ana-María; González-Quintanilla, Vicente; López-de-Silanes, Carlos; Martínez-Rodríguez, José-Enrique; Costa-Frossard, Lucienne; Garcés-Redondo, M; Labiano-Fontcuberta, Andrés; Castellanos-Pinedo, Fernando; García-Merino, Juan-Antonio; Muñoz-Fernández, Carmen; Castillo-Trivino, Tamara; Meca-Lallana, Virginia; Peña-Martínez, Joaquín; Rodríguez-Antiguedad, Alfredo; Prieto-González, José-María; Agüera-Morales, Eduardo; Pérez-Molina, Inmaculada; Solar-Sánchez, Dulce-M; Herrera-Varo, Nicolás; Aguirre-Vázquez, Marta; Rodríguez-Barrios, José-Manuel; Rio, Jordi (BMC, 2025-04-10)
    BACKGROUND: To estimate the socioeconomic burden of people with secondary progressive multiple sclerosis (pwSPMS), considering direct health care, direct non-health care, and indirect costs, and to evaluate the relationship ...
  • Construction and validation of the "labour ward job satisfaction scale for midwives (LWJSS-M)" in Spain 
    Pérez-Castejon, Marta; Martínez-Alarcón, Laura; Leal-Costa, César; Suárez-Cortés, María; Vera-Pérez, José-Antonio; Jiménez-Ruiz, Ismael (BMC, 2025-10-14)
    BACKGROUND: Midwives' job satisfaction is essential to ensuring high quality obstetric care and promoting the well-being of both women and healthcare professionals. However, the medicalised model of childbirth and role ...
  • Development and validation of checklists for standardized patients in dental education for special care health needs patients 
    Guerrero-Gironés, Julia; Mellinas-Martínez, Irene; Pecci-Lloret, Miguel-Ramón; Adánez-Martínez, Gracia; Pecci-Lloret, María-Pilar (BMC, 2025-12-19)
    BACKGROUND: Traditionally, checklists or evaluation templates have been utilized to assess psychological and health-related issues in fields like psychology and pediatrics. Currently, their use has expanded, particularly ...
  • Mortality attributable to modifiable lifestyle factors in the Spanish cohort of the European prospective investigation into cancer and nutrition (EPIC) study 
    Cirera-Suárez, LLuis; Huerta-Castaño, José-María; Moreno-Iribas, Conchi; Jiménez, Ana; Mokoroa, Olatz; Guevara, Marcela; Andueza, Naroa; Sánchez, María-José; Petrova, Dafina; Luján-Barroso, Leila; Salmerón-Martínez, Diego; Chirlaque-López, María-Dolores (BMC, 2025-11-26)
    BACKGROUND: There is consistent evidence on the relationship of unhealthy habits with mortality risk. The population attributable fraction (PAF) is a useful quantifier of the number of new disease cases attributable to ...

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