Repositorio Dspace

Envíos recientes

03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla): Envíos recientes

  • Prospective study of predictors for anxiety, depression, and somatization in a sample of 1807 cancer patients 
    Velasco-Durantez, Verónica; Cruz-Castellanos, Patricia; Hernández, Raquel; Rodríguez-González, Adan; Fernández-Montes, Ana; Gallego, Alejandro; Manzano-Fernández, Aranzazu; Sorribes, Elena; Zafra, Marta; Carmona-Bayonas, Alberto; Calderon, Caterina; Jiménez-Fonseca, Paula (NATURE PORTFOLIO, 2024-02)
    In cancer patients, psychological distress, which encompasses anxiety, depression, and somatization, arises from the complex interplay of emotional and behavioral reactions to the diagnosis and treatment, significantly ...
  • Pathogenic NLRP3 mutants form constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1? production 
    Molina-López, Cristina; Hurtado-Navarro, Laura; García, Carlos-J; Angosto-Bazarra, Diego; Vallejo, Fernando; Tapia-Abellan, Ana; Marques-Soares, Joana-R; Vargas, Carmen; Bujan-Rivas, Segundo; Tomás-Barberan, Francisco-A; Arostegui, Juan-I; Pelegrín, Pablo (NATURE PORTFOLIO, 2024-02)
    Cryopyrin-associated periodic syndrome (CAPS) is an autoinflammatory condition resulting from monoallelic NLRP3 variants that facilitate IL-1? production. Although these are gain-of-function variants characterized by ...
  • Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression 
    Molina, Oscar; Ortega-Sabater, Carmen; Thampi, Namitha; Fernández-Fuentes, Narcis; Guerrero-Murillo, Mercedes; Martínez-Moreno, Alba; Vinyoles, Meritxell; Velasco-Hernández, Talia; Bueno, Clara; Trincado, Juan-L; Granada, Isabel; Campos, Diana; Giménez, Carles; Boer, Judith-M; den-Boer, Monique-L; Calvo, Gabriel-F; Camos, Mireia; Fuster, José-Luis; Velasco, Pablo; Ballerini, Paola; Locatelli, Franco; Mullighan, Charles-G; Spierings, Diana-CJ; Foijer, Floris; Pérez-García, Victor-M; Menendez, Pablo (SPRINGERNATURE, 2024-01-16)
    Chromosomal instability (CIN) lies at the core of cancer development leading to aneuploidy, chromosomal copy-number heterogeneity (chr-CNH) and ultimately, unfavorable clinical outcomes. Despite its ubiquity in cancer, the ...
  • Cryopreservation of highly extended pig spermatozoa remodels its proteome and counteracts polyspermic fertilization in vitro 
    Parrilla, Inmaculada; Cambra, Josep-M; Cuello, Cristina; Rodríguez-Martínez, Heriberto; Gil, María-A; Martínez, Emilio-A (WILEY, 2024-09)
    BACKGROUND: Currently, high polyspermy remains a significant obstacle to achieving optimal efficiency in in vitro fertilization (IVF) and in vitro embryo production (IVP) systems in pigs. Developing strategies that would ...
  • Dietary index based on the Food Standards Agency nutrient profiling system and risk of Crohn's disease and ulcerative colitis 
    Meyer, Antoine; Dong, Catherine; Chan, Simon-SM; Touvier, Mathilde; Julia, Chantal; Huybrechts, Inge; Nicolas, Genevieve; Oldenburg, Bas; Heath, Alicia-K; Tong, Tammy-YN; Key, Timothy-J; Tjonneland, Anne; Kyro, Cecilie; Kaaks, Rudolf; Katzke, Verena-A; Bergman, Manuela-M; Palli, Domenico; Masala, Giovanna; Tumino, Rosario; Sacerdote, Carlotta; Colorado-Yohar, Sandra-Milena; Sánchez, María-José; Guevara, Marcela; Grip, Olof; Holmgren, Johanna; Cross, Amanda; Karling, Pontus; Hultdin, Johan; Murphy, Neil; Deschasaux-Tanguy, Melanie; Hercberg, Serge; Galan, Pilar; Mahamat-Saleh, Yahya; Amiot, Aurelien; Gunter, Marc-J; Boutron-Ruault, Marie-Christine; Carbonnel, Franck (WILEY, 2024-02)
    BACKGROUND: Nutri-score is now widely available in food packages in Europe. AIM: To study the overall nutritional quality of the diet in relation to risks of Crohn's disease (CD) and ulcerative colitis (UC), in the European ...
  • Expert Revision of Key Elements for Clinical-Grade Production and Qualification of Perinatal Derivatives 
    Gramignoli, Roberto; Hofmann, Nicola; Agudo-Barriuso, Marta; Antica, Maríastefania; Flores, Ana, I; Girandon, Lenart; Kerdjoudj, Halima; Navakauskiene, Ruta; Schiavi, Jessica; Scholz, Hanne; Shablii, Volodymyr; Lafarge, Xavier; Nicolas, Francisco-J; Gindraux, Florelle (OXFORD UNIV PRESS, 2024-01-12)
    Perinatal derivatives have been proposed as adjunct therapeutic strategies or innovative treatments. Undoubtedly, perinatal derivatives can offer the opportunity and source material to isolate multipotent stem cells, but ...
  • Spatial-temporal simulation for hospital infection spread and outbreaks of Clostridioides difficile 
    Kim, Denisse; Canovas-Segura, Bernardo; Jimeno-Almazan, Amaya; Campos, Manuel; Juárez, José-M (NATURE PORTFOLIO, 2023-11)
    Validated and curated datasets are essential for studying the spread and control of infectious diseases in hospital settings, requiring clinical information on patients' evolution and their location. The literature shows ...
  • SARAF overexpression impairs thrombin-induced Ca2+ homeostasis in neonatal platelets 
    Berna-Erro, Alejandro; Granados, María-P; Teruel-Montoya, Raul; Ferrer-Marín, Francisca; Delgado, Elena; Corbacho, Antonio-J; Fenandez, Esperanza; Vazquez-Godoy, María-T; Tapia, José-A; Redondo, Pedro-Cosme (WILEY, 2024-03)
    Neonatal platelets present a reduced response to the platelet agonist, thrombin (Thr), thus resulting in a deficient Thr-induced aggregation. These alterations are more pronounced in premature newborns. Here, our aim was ...
  • Machine Learning Improves Risk Stratification in Myelodysplastic Neoplasms: An Analysis of the Spanish Group of Myelodysplastic Syndromes 
    Mosquera-Orgueira, Adrian; Pérez-Encinas, Manuel-Mateo; Diaz-Varela, Nicolas-A; Mora, Elvira; Diaz-Beya, Marina; Montoro, María-Julia; Pomares, Helena; Ramos, Fernando; Tormo, Mar; Jerez-Cayuela, Andrés; Nomdedeu, Josep-F; De-Miguel-Sánchez, Carlos; Leonor, Arenillas; Carcel, Paula; Cedena-Romero, María-Teresa; Xicoy, Blanca; Rivero, Eugenia; del-Orbe-Barreto, Rafael-Andres; Diez-Campelo, María; Benlloch, Luis-E; Crucitti, Davide; Valcarcel, David (WILEY, 2023-10)
    Myelodysplastic neoplasms (MDS) are a heterogeneous group of hematological stem cell disorders characterized by dysplasia, cytopenias, and increased risk of acute leukemia. As prognosis differs widely between patients, and ...
  • Polyphenols as NLRP3 inflammasome modulators in cardiometabolic diseases: a review of in vivo studies 
    Villalva, Marisol; Martínez-García, Juan-José; Jaime, Laura; Santoyo, Susana; Pelegrín, Pablo; Pérez-Jiménez, Jara (ROYAL SOC CHEMISTRY, 2023-10)
    The nucleotide-binding domain and leucine-rich repeat containing receptors (NLRs) are components of the innate immune system, important in coordinating the inflammatory response. Among them, NLRP3 can form inflammasomes, ...
  • Cortical Lewy body injections induce long-distance pathogenic alterations in the non-human primate brain 
    Teil, Margaux; Dovero, Sandra; Bourdenx, Mathieu; Arotcarena, Marie-Laure; Darricau, Morgane; Porras, Gregory; Thiolat, Marie-Laure; Trigo-Damas, Ines; Perier, Celine; Estrada, Cristina; García-Carrillo, Nuria; Herrero, María-Trinidad; Vila, Miquel; Obeso, José-A; Bezard, Erwan; Dehay, Benjamin (NATURE PORTFOLIO, 2023-09)
    Aggregation of ?-synuclein (?-syn) is the cornerstone of neurodegenerative diseases termed synucleinopathies, which include Parkinson's Disease (PD), Dementia with Lewy Bodies (DLB), and Multiple System Atrophy (MSA). These ...
  • Impact of inclusion of post-spermatic ejaculate fraction in boar seminal doses on sperm metabolism, quality, and interaction with uterine fluid 
    Luongo, Chiara; José-Llamas-López, Pedro; Garrappa, Gabriela; Rodríguez-Tobon, Ernesto; Grudzinska, Paulina; Alberto-García-Vazquez, Francisco (NATURE PORTFOLIO, 2023-09)
    Boar ejaculate is composed of sperm cells and seminal plasma (SP) and is emitted in different fractions (pre-sperm fraction; spermatic-rich fraction; intermediate fraction; post-spermatic fraction), with different composition ...
  • The ERA Registry Annual Report 2020: a summary 
    Astley, Megan-E; Boenink, Rianne; Abd-ElHafeez, Samar; Trujillo-Aleman, Sara; Arribas, Federico; Asberg, Anders; Beckerman, Pazit; Bell, Samira; Bouzas-Caamano, María-Encarnacion; Farnes, Jordi-Comas; Galvao, Ana-Amelia; Gjorgjievski, Nikola; Kelmendi, Vjollca-Godanci; Guidotti, Rebecca; Helve, Jaakko; Idrizi, Alma; Indridason, Olafur-S; Ioannou, Kyriakos; Kerschbaum, Julia; Komissarov, Kirill; de-la-Nuez, Pablo-Castro; Lassalle, Mathilde; Nordio, Maurizio; Arevalo, Olga-Lucia-Rodríguez; Santiuste-de-Pablos, Carmen; Seyahi, Nurhan; Roblero, María-Fernanda-Slon; Steenkamp, Retha; ten-Dam, Marc-AGJ; Zakharova, Elena, V; Ziginskiene, Edita; Bonthuis, Marjolein; Stel, Vianda-S; Ortiz, Alberto; Jager, Kitty-J; Kramer, Anneke (OXFORD UNIV PRESS, 2023-07)
    BACKGROUND: The European Renal Association (ERA) Registry collects data on kidney replacement therapy (KRT) in patients with ESKD. This paper is a summary of the ERA Registry Annual Report 2020, also including comparisons ...
  • Application of IPSET-thrombosis in 1366 Patients Prospectively Followed From the Spanish Registry of Essential Thrombocythemia 
    Alvarez-Larran, Alberto; Cuevas, Beatriz; Velez, Patricia; Noya, Soledad; Caballero-Navarro, Gonzalo; Ferrer-Marín, Francisca; Carbonell, Sara; Pérez-Encinas, Manuel; Teresa-Gómez-Casares, María; Pérez-López, Raul; Magro, Elena; Moreto, Ana; Pastor-Galan, Irene; Angona, Anna; Isabel-Mata-Vazquez, María; Guerrero-Fernández, Lucia; María-Guerra, José; Carreno-Tarragona, Gonzalo; Fox, Laura; Murillo, Ilda; García-Gutierrez, Valentin; Mora, Elvira; Stuckey, Ruth; Arellano-Rodrigo, Eduardo; Carlos-Hernández-Boluda, Juan; Pereira, Arturo; MPN-Spanish-Grp-GEMFIN (WILEY, 2023-08)
    The International Prognostic Score of thrombosis in Essential Thrombocythemia (IPSET-thrombosis) and its revised version have been proposed to guide thrombosis prevention strategies. We evaluated both classifications to ...
  • Association between Covid-19 sources of information, beliefs, and vaccination rates: an EU-wide survey 
    De-la-Cruz-Sánchez, Ernesto; Moreno-Llamas, Antonio; Olivares, Jaime-Mendiola; García-Mayor, Jesus; Torres-Cantero, Alberto; Devine, Emily-Beth (OXFORD UNIV PRESS, 2023-10)
    BACKGROUND: Misinformation hampers vaccine uptake. The European Union (EU) employed a coordinated effort to curb misinformation during the Covid-19 pandemic. In this context, we investigated relationships between sources ...
  • ASC oligomer favors caspase-1CARD domain recruitment after intracellular potassium efflux 
    Martín-Sánchez, Fatima; Compan, Vincent; Penin-Franch, Alejandro; Tapia-Abellan, Ana; Gómez, Ana-II; Banos-Gregori, María-C; Schmidt, Florian-II; Pelegrín, Pablo (ROCKEFELLER UNIV PRESS, 2023-07)
    Signaling through the inflammasome is important for the inflammatory response. Low concentrations of intracellular K+ are associated with the specific oligomerization and activation of the NLRP3 inflammasome, a type of ...
  • Effect of oral antiseptics in reducing SARS-CoV-2 infectivity: evidence from a randomized double-blind clinical trial 
    Sánchez-Barrueco, Alvaro; Victoria-Mateos-Moreno, María; Martínez-Beneyto, Yolanda; García-Vazquez, Elisa; Campos-González, Alfonso; Zapardiel-Ferrero, Javier; Bogoya-Castano, Abel; Alcala-Rueda, Ignacio; Villacampa-Auba, José-Miguel; Cenjor-Espanol, Carlos; Moreno-Parrado, Laura; Ausina-Marquez, Verónica; García-Esteban, Sandra; Artacho, Alejandro; Xavier-López-Labrador, F; Mira, Alex; Ferrer, María-D (TAYLOR & FRANCIS LTD, 2022-12-31)
    ABSTRACTBackground: In vitro studies have shown that several oral antiseptics have virucidal activity against SARS-CoV-2. Thus, mouthwashes have been proposed as an easy to implement strategy to reduce viral transmission. ...
  • In vitro bacteriological effect of tri-beveled needle electrolysis against Staphylococcus aureus 
    García-Vidal, José-Antonio; Salinas, Jesus; Ortega, Nieves; Escolar-Reina, Pilar; Camacho-Alonso, Fabio; Medina-Mirapeix, Francesc (NATURE PORTFOLIO, 2022-07)
    Percutaneous needle electrolysis using tri-beveled needles with a specific protocol (5 mA applied for 25 s) has demonstrated to provoke a clinical reduction of recurrent bacterial infections in mammary fistulas. However, ...
  • Long-Read Sequencing Identifies the First Retrotransposon Insertion and Resolves Structural Variants Causing Antithrombin Deficiency 
    De-La-Morena-Barrio, Belen; Stephens, Jonathan; Eugenia-De-La-Morena-Barrio, María; Stefanucci, Luca; Padilla, José; Minano, Antonia; Gleadall, Nicholas; Luis-García, Juan; Fernanda-López-Fernández, María; Morange, Pierre-Emmanuel; Puurunen, Marja; Undas, Anetta; Vidal, Francisco; Raymond, Frances-Lucy; Vicente, Vicente; Ouwehand, Willem-H; Corral, Javier; Sanchis-Juan, Alba (GEORG THIEME VERLAG KG, 2022-08)
    The identification of inherited antithrombin deficiency (ATD) is critical to prevent potentially life-threatening thrombotic events. Causal variants in SERPINC1 are identified for up to 70% of cases, the majority being ...
  • Saliva changes in composition associated to COVID-19: a preliminary study 
    Munoz-Prieto, Alberto; Rubic, Ivana; Carlos-González-Sánchez, Juan; Kules, Josipa; Martínez-Subiela, Silvia; Joaquin-Ceron, José; Bernal-Morell, Enrique; Torres-Cantero, Alberto; Rosario-Vicente-Romero, María; Mrljak, Vladimir; Tvarijonaviciute, Asta (NATURE PORTFOLIO, 2022-06)
    The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2), is usually associated with a wide variety of clinical presentations from asymptomatic to severe cases. ...

Buscar en DSpace


Búsqueda avanzada

Listar

Mi cuenta