Repositorio Dspace

Envíos recientes

03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla): Envíos recientes

  • Training, detraining and retraining effects of moderate vs. high intensity exercise training programme on cardiovascular risk factors 
    Avila-Gandia, Vicente; Ramos-Campo, Domingo-Jesus; García-Sánchez, Esther; Luque-Rubia, Antonio-Jesus; López, Asensio; López-Roman, Francisco-Javier (LIPPINCOTT WILLIAMS & WILKINS, 2023-03)
    BACKGROUND: The aim of the present study was to analyse the effect of 12 weeks of training, 7 weeks of detraining and 16 weeks of retraining using a moderate or high intensity training programme on cardiovascular risk ...
  • Patient selection, peri-procedural management, and ablation techniques for catheter ablation of atrial fibrillation: an EHRA survey 
    Iliodromitis, Konstantinos; Lenarczyk, Radoslaw; Scherr, Daniel; Conte, Giulio; Farkowski, Michal-M; Marín, Francisco; García-Seara, Javier; Simovic, Stefan; Potpara, Tatjana (OXFORD UNIV PRESS, 2023-02)
    Catheter ablation (CA) of atrial fibrillation (AF) is the therapy of choice for the maintenance of sinus rhythm in patients with symptomatic AF. Time towards interventional treatment and peri-procedural management of ...
  • Sleep quality among inpatients of Spanish public hospitals 
    Bellon, Filip; Stremler, Robyn; Rubinat-Arnaldo, Esther; Padilla-Martínez, Julia-M; Casado-Ramirez, Elvira; Sánchez-Ortuno, Montserrat; Gea-Sánchez, Montserrat; Martín-Vaquero, Yolanda; Moreno-Casbas, Teresa; Abad-Corpa, Eva (NATURE PORTFOLIO, 2022-12-20)
    Sleep is a complex process and is needed both in health and illness. Deprivation of sleep is known to have multiple negative physiological effects on people's bodies and minds. Despite the awareness of these harmful effects, ...
  • Binucleated human bone marrow-derived mesenchymal cells can be formed during neural-like differentiation with independence of any cell fusion events 
    Bueno, Carlos; Blanquer, Miguel; García-Bernal, David; Martínez, Salvador; Moraleda-Jiménez, José-María (NATURE PORTFOLIO, 2022-11)
    Although it has been reported that bone marrow-derived cells (BMDCs) can transdifferentiate into neural cells, the findings are considered unlikely. It has been argued that the rapid neural transdifferentiation of BMDCs ...
  • Anti-inflammatory potential of digested Brassica sprout extracts in human macrophage-like HL-60 cells 
    García-Ibanez, Paula; Nunez-Sánchez, María-A; Oliva-Bolarin, Alba; Martínez-Sánchez, María-A; Ramos-Molina, Bruno; Ruiz-Alcaraz, Antonio-J; Moreno, Diego-A (ROYAL SOC CHEMISTRY, 2023-01-03)
    Cruciferous vegetables have been reported to be a great source of anti-inflammatory compounds. Specifically, sprouts from the Brassicaceae family stand out for their high content of glucosinolates (and their bioactive ...
  • Contemporary management of atrial fibrillation and the predicted vs. absolute risk of ischaemic stroke despite treatment: a report from ESC-EHRA EORP-AF Long-Term General Registry 
    Ding, Wern-Yew; Blomstrom-Lundqvist, Carina; Fauchier, Laurent; Marín, Francisco; Potpara, Tatjana-S; Boriani, Giuseppe; Lip, Gregory-YH (OXFORD UNIV PRESS, 2023-02)
    BACKGROUND: Risk stratification in patients with atrial fibrillation (AF) is important to facilitate guideline-directed therapies. The Calculator of Absolute Stroke Risk (CARS) scheme enables an individualized estimation ...
  • Androgen receptor polyQ alleles and COVID-19 severity in men: A replication study 
    López-Rodríguez, Rosario; Ruiz-Hornillos, Javier; Corton, Marta; Almoguera, Berta; Minguez, Pablo; Elena-Pérez-Tomás, María; Barreda-Sánchez, María; Mancebo, Esther; Ondo, Lorena; Martínez-Ramas, Andrea; Fernández-Caballero, Lidia; Carlos-Taracido-Fernández, Juan; Herrero-González, Antonio; Mahillo, Ignacio; Paz-Artal, Estela; Guillén-Navarro, Encarna; Ayuso, Carmen (WILEY, 2023-01)
    BACKGROUND: Ample evidence indicates a sex-related difference in severity of COVID-19, with less favorable outcomes observed in men. Genetic factors have been proposed as candidates to explain this difference. The polyglutamine ...
  • Microbial bile salt hydrolase activity influences gene expression profiles and gastrointestinal maturation in infant mice 
    Nunez-Sánchez, María-A; Herisson, Florence-M; Keane, Jonathan-M; García-González, Natalia; Rossini, Valerio; Pinhiero, Jorge; Daly, Jack; Bustamante-Garrido, Milan; Hueston, Cara-M; Patel, Shriram; Canela, Nuria; Herrero, Pol; Claesson, Marcus-J; Melgar, Silvia; Nally, Ken; Caplice, Noel-M; Gahan, Cormac-GM (TAYLOR & FRANCIS INC, 2022-12-31)
    The mechanisms by which early microbial colonizers of the neonate influence gut development are poorly understood. Bacterial bile salt hydrolase (BSH) acts as a putative colonization factor that influences bile acid ...
  • The impact of resilience as a protective factor on Health-Related Quality of Life's psychological dimensions among adolescents who experience peer victimization 
    de-Lourdes-Martín-Pérez, Angela; Moran-Sánchez, Ines; José-Gascon-Canovas, Juan (NATURE PORTFOLIO, 2022-11)
    Peer victimization have a negative impact on Health-Related Quality of Life (HRQoL) during adolescence, however some personal skills such a person's resilience could play a significant role in this relationship. In this ...
  • Zebrafish models of COVID-19 
    Tyrkalska, Sylwia-D; Candel, Sergio; Pedoto, Annamaria; García-Moreno, Diana; Alcaraz-Pérez, Francisca; Sánchez-Ferrer, Alvaro; Cayuela, María-L; Mulero, Victoriano (OXFORD UNIV PRESS, 2023-01-16)
    Although COVID-19 has only recently appeared, research studies have already developed and implemented many animal models for deciphering the secrets of the disease and provided insights into the biology of SARS-CoV-2. ...
  • Enforced mesenchymal stem cell tissue colonization counteracts immunopathology 
    García-Bernal, David; Blanquer, Miguel; Martínez, Carlos-M; García-Guillen, Ana, I; García-Hernández, Ana-M; Carmen-Alguero, M; Yanez, Rosa; Lamana, María-L; Moraleda-Jiménez, José-María; Sackstein, Robert (NATURE PORTFOLIO, 2022-10)
    Mesenchymal stem/stromal cells (MSCs) are distributed within all tissues of the body. Though best known for generating connective tissue and bone, these cells also display immunoregulatory properties. A greater understanding ...
  • P2X7 receptor activation impairs antitumour activity of natural killer cells 
    Baroja-Mazo, Alberto; Penin-Franch, Alejandro; Lucas-Ruiz, Fernando; De-Torre-Minguela, Carlos; Alarcon-Vila, Cristina; Hernández-Caselles, Trinidad; Pelegrín, Pablo (WILEY, 2023-01)
    BACKGROUND AND PURPOSE: A high number of intratumoural infiltrating natural killer (NK) cells is associated with better survival in several types of cancer, constituting an important first line of defence against tumours. ...
  • Smoking remains associated with education after controlling for social background and genetic factors in a study of 18 twin cohorts 
    Silventoinen, Karri; Piirtola, Maarit; Jelenkovic, Aline; Sund, Reijo; Tarnoki, Adam-D; Tarnoki, David-L; Medda, Emanuela; Nistico, Lorenza; Toccaceli, Virgilia; Honda, Chika; Inui, Fujio; Tomizawa, Rie; Watanabe, Mikio; Sakai, Norio; Gatz, Margaret; Butler, David-A; Lee, Jooyeon; Lee, Soo-Ji; Sung, Joohon; Franz, Carol-E; Kremen, William-S; Lyons, Michael-J; Derom, Catherine-A; Vlietinck, Robert-F; Loos, Ruth-JF; Tynelius, Per; Rasmussen, Finn; Martín, Nicholas-G; Medland, Sarah-E; Montgomery, Grant-W; Brandt, Ingunn; Nilsen, Thomas-S; Harris, Jennifer-R; Tyler, Jessica; Hopper, John-L; Magnusson, Patrik-KE; Pedersen, Nancy-L; Aslan, Anna-KDahl; Ordonana, Juan-R; Sánchez-Romera, Juan-F; Colodro-Conde, Lucia; Rebato, Esther; Zhang, Dongfeng; Pang, Zengchang; Tan, Qihua; Silberg, Judy-L; Maes, Hermine-H; Boomsma, Dorret, I; Sorensen, Thorkild-IA; Korhonen, Tellervo; Kaprio, Jaakko (NATURE PORTFOLIO, 2022-07)
    We tested the causality between education and smoking using the natural experiment of discordant twin pairs allowing to optimally control for background genetic and childhood social factors. Data from 18 cohorts including ...
  • Oleanolic acid stimulation of cell migration involves a biphasic signaling mechanism 
    Stelling-Ferez, Javier; Antonio-Gabaldon, José; José-Nicolas, Francisco (NATURE PORTFOLIO, 2022-09)
    Cell migration is a critical process for wound healing, a physiological phenomenon needed for proper skin restoration after injury. Wound healing can be compromised under pathological conditions. Natural bioactive terpenoids ...
  • Detection of kinase domain mutations in BCR::ABL1 leukemia by ultra-deep sequencing of genomic DNA 
    Sánchez, Ricardo; Dorado, Sara; Ruiz-Heredia, Yanira; Martín-Munoz, Alejandro; Manuel-Rosa-Rosa, Juan; Ribera, Jordi; García, Olga; Jiménez-Ubieto, Ana; Carreno-Tarragona, Gonzalo; Linares, María; Rufian, Laura; Juárez, Alexandra; Carrillo, Jaime; José-Espino, María; Caceres, Mercedes; Exposito, Sara; Cuevas, Beatriz; Vanegas, Raul; Felipe-Casado, Luis; Torrent, Anna; Zamora, Lurdes; Mercadal, Santiago; Coll, Rosa; Cervera, Marta; Morgades, Mireia; Angel-Hernández-Rivas, José; Bravo, Pilar; Seri, Cristina; Anguita, Eduardo; Barragan, Eva; Sargas, Claudia; Ferrer-Marín, Francisca; Sánchez-Calero, Jorge; Sevilla, Julián; Ruiz, Elena; Villalon, Lucia; del-Mar-Herraez, María; Riaza, Rosalia; Magro, Elena; Luis-Steegman, Juan; Wang, Chongwu; de-Toledo, Paula; García-Gutierrez, Valentin; Ayala, Rosa; Ribera, Josep-María; Barrio, Santiago; Martínez-López, Joaquin (NATURE PORTFOLIO, 2022-07)
    The screening of the BCR::ABL1 kinase domain (KD) mutation has become a routine analysis in case of warning/failure for chronic myeloid leukemia (CML) and B-cell precursor acute lymphoblastic leukemia (ALL) Philadelphia ...
  • Dystonia genes functionally converge in specific neurons and share neurobiology with psychiatric disorders 
    Mencacci, Niccolo-E; Reynolds, Regina; Ruiz, Sonia-García; Vandrovcova, Jana; Forabosco, Paola; Sánchez-Ferrer, Alvaro; Volpato, Viola; Weale, Michael-E; Bhatia, Kailash-P; Webber, Caleb; Hardy, John; Botia, Juan-A; Ryten, Mina (OXFORD UNIV PRESS, 2020-09)
    Dystonia is a neurological disorder characterized by sustained or intermittent muscle contractions causing abnormal movements and postures, often occurring in absence of any structural brain abnormality. Psychiatric ...
  • Case report of Tourniquet ALPPS and simultaneous sleeve gastrectomy A valuable association to achieve an adequate future liver remnant in obese patients 
    Brusadin, Roberto; López-López, Victor; Ruiz-de-Angulo, David; López-Conesa, Asuncion; Navarro-Barrios, Alvaro; Caballero-Planes, Albert; Parrilla-Paricio, Pascual; Robles-Campos, Ricardo (LIPPINCOTT WILLIAMS & WILKINS, 2020-08-21)
    INTRODUCTION: Obesity represents a risk factor in case of major hepatectomy, because the future liver remnant (FLR) must be proportional with body weight. To avoid post-hepatectomy liver failure, and further increase the ...
  • Mediating effect of soluble B-cell activation immune markers on the association between anthropometric and lifestyle factors and lymphoma development 
    Hosnijeh, Fatemeh-Saberi; Kolijn, Pieter-M; Casabonne, Delphine; Nieters, Alexandra; Solans, Marta; Naudin, Sabine; Ferrari, Pietro; Mckay, James-D; Weiderpass, Elisabete; Perduca, Vittorio; Besson, Caroline; Mancini, Francesca-Romana; Masala, Giovanna; Krogh, Vittorio; Ricceri, Fulvio; Huerta-Castaño, José-María; Petrova, Dafina; Sala, Nuria; Trichopoulou, Antonia; Karakatsani, Anna; La-Vecchia, Carlo; Kaaks, Rudolf; Canzian, Federico; Aune, Dagfinn; Boeing, Heiner; Schulze, Matthias-B; Pérez-Cornago, Aurora; Langerak, Anton-W; van-der-Velden, Vincent-HJ; Vermeulen, Roel (NATURE PORTFOLIO, 2020-08-14)
    Sustained B-cell activation is an important mechanism contributing to B-cell lymphoma (BCL). We aimed to validate four previously reported B-cell activation markers predictive of BCL risk (sCD23, sCD27, sCD30, and CXCL13) ...
  • Effectiveness of individualized inhaler technique training on low adherence (LowAd) in ambulatory patients with COPD and asthma 
    Miguel-Sánchez-Nieto, Juan; Bernabeu-Mora, Roberto; Fernández-Munoz, Irene; Carrillo-Alcaraz, Andres; Alcantara-Fructuoso, Juan; Fernández-Alvarez, Javier; Carlos-Vera-Olmos, Juan; José-Martínez-Ferre, María; Garci-Varela-Olea, Mercedes; Corcoles-Valenciano, María-José; Salmerón-Martínez, Diego (NATURE PORTFOLIO, 2022-01-10)
    To analyze whether there is improvement in adherence to inhaled treatment in patients with COPD and asthma after an educational intervention based on the teach-to-goal method. This is a prospective, non-randomized, ...
  • Incidence of myeloid neoplasms in Spain (2002-2013): a population-based study of the Spanish network of cancer registries 
    Solans, Marta; Sanvisens, Arantza; Ameijide, Alberto; Merino, Susana; Rojas, Dolores; Aleman, Araceli; Banqueri, Emilia; Chico, Matilde; Marcos, Ana-Isabel; de-Castro, Visitacion; Gil, Leire; de-Munain, Arantza-López; Puigdemont, Montse; Sánchez, María-José; Perucha, Josefina; Ruiz-Armengol, Patricia; Chirlaque-López, María-Dolores; Guevara, Marcela; Carulla, María; Marcos-Gragera, Rafael (NATURE PORTFOLIO, 2022-01-10)
    Comprehensive population-based data on myeloid neoplasms (MNs) are limited, mainly because some subtypes were not recognized as hematological cancers prior to the WHO publication in 2001, and others are too rare to allow ...

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