OBJECTIVES: Long-acting injectable cabotegravir and rilpivirine (LAI CAB+RPV) provides an alternative to daily therapy for people with HIV (PWH) with virologic suppression. Although genotypic testing is recommended before ...
INTRODUCTION: Severe asthma (SA) management requires a comprehensive, individualized approach with continuous pharmacological treatment adjustments. In SA patients controlled with biologics, decisions on how to adjust ...
BACKGROUND: Neuropathic pain (NP) is a complex chronic condition with limited therapeutic effectiveness. Despite multiple drug classes and international guidelines, real-world adherence remains inconsistent, and data on ...
BACKGROUND: Currently, integrase strand-transfer inhibitors (INSTIs) are the cornerstone of antiretroviral therapy (ART), providing potent viral suppression and good tolerability. Emerging evidence suggests that INSTI-based ...
BACKGROUND: Despite adjuvant systemic chemotherapy after surgical resection in patients with pT4 stage colon cancer, a high percentage of them will develop peritoneal metastases. Intraoperative hyperthermic intraperitoneal ...
Background/Objectives: Olfactory dysfunction and dysgeusia are common neurosensory manifestations of Coronavirus Disease 2019 (COVID-19), affecting approximately 60% of patients. These symptoms have been mechanistically ...
Iniesta-Navalon, Carles; Ríos-Saorín, Manuel; Rentero-Redondo, Lorena; Nicolas-de-Prado, Isabel; Gómez-Espín, Rosa; Urbieta-Sanz, Elena(ARAN EDICIONES, S A, 2024)
BACKGROUND: understanding the relationship between ustekinumab (UST) exposure and clinical outcomes in inflammatory bowel disease (IBD) induction is crucial. However, evidence remains limited, highlighting the need to ...
Aguado, HJ(BRITISH EDITORIAL SOC BONE & JOINT SURGERY, 2025-01-09)
AIMS: The Peri-Implant and PeriProsthetic Survival AnalysiS (PIPPAS) study aimed to investigate the risk factors for one-year mortality of femoral peri-implant fractures (FPIFs). METHODS: This prospective, multicentre, ...
OBJECTIVES: To evaluate the long-term effectiveness, persistence and tolerability of dolutegravir (DTG)/lamivudine (3TC), compared with the most frequently prescribed first-line treatment regimens, among antiretroviral-naive ...
Introduction: patients with neurodegenerative diseases and diabetes are at high risk of malnutrition. Enteral tube feeding improves prognosis by ensuring a continuous supply of essential nutrients, optimizing glycemic ...
OBJECTIVES: Long-acting injectable cabotegravir and rilpivirine (LAI CAB+RPV) provides an alternative to daily therapy for people with HIV (PWH) with virologic suppression. Although genotypic testing is recommended before ...
D'amico, Ronald; Han, Kelong; Min, Sherene; Demoor, Rebecca; St. Clair, Marty; Ford, Susan L.; Harrington, Conn; Bernal-Morell, Enrique; Lombaard, Johannes; Crauwels, Herta; Kolobova, Irina; Patel, Natasha; Jamil, Nasir; Van Solingen-Ristea, Rodica; Acuipil, Carolina; Spreen, William(LIPPINCOTT WILLIAMS & WILKINS, 2025-12-01)
OBJECTIVE: To evaluate subcutaneous anterior abdominal injections of long-acting cabotegravir plus rilpivirine (CAB + RPV LA) in participants with more than 3 years' experience with intramuscular injections in the Phase 3 ...
BACKGROUND: Hepatic steatosis, commonly associated with metabolic dysfunction-associated steatotic liver disease, is a growing but underdiagnosed concern in people with human immunodeficiency virus (HIV). This study evaluates ...
The past decade has seen changing trends in anterior cruciate ligament reconstruction surgery, with the hamstring becoming the most commonly used graft. Furthermore, the importance of extra-articular lateral tenodesis has ...
INTRODUCTION: In 2017, the Spanish Academy of Dermatology and Venereology Psoriasis Working Group (PWG) designed the Minimal Disease Activity (MDA) criteria to determine the level of disease activity. We hereby present the ...
Sanz-Ruize, Pablo; Ramon Caeiro-Rey, Jose; Carlos Martinez-Pastor, Juan; Luis Martin-Alguacil, Jose; Murcia-Asensio, Antonio; Moreta, Jesus(BIOSCIENTIFICA LTD, 2025-02-01)
Wounds in orthopaedic surgery differ from wounds in other surgical fields in various ways. Tissues that are highly affected due to the trauma itself, the presence of an orthopaedic implant and the performance of prosthetic ...