BACKGROUND: The impact of pre-existing non-nucleoside reverse transcriptase inhibitor (NNRTI) resistance-associated mutations (RAMs) on the effectiveness of long-acting (LA) cabotegravir (CAB) and rilpivirine (RPV) remains ...
BACKGROUND: This study of people with HIV (PWH) receiving CAB + RPV LAI evaluated its effectiveness, safety, and impact on inflammatory markers, body fat/lean mass distributions, quality of life, sleep, health satisfaction, ...
Background: Platelet-rich plasma (PRP) is utilised in the treatment of patellofemoral chondropathy, although clinical responses remain variable. This retrospective exploratory study assessed whether baseline quantitative ...
BACKGROUND: While surveillance drug resistance mutations (SDRMs) remain essential for monitoring transmitted drug resistance (TDR), the clinical impact of transmitted resistance for current first-line regimens has become ...
Background/Objectives: Alignment philosophy in total knee arthroplasty (TKA) may affect joints beyond the knee. Mechanical alignment (MA) targets a neutral mechanical axis, whereas kinematic alignment (KA) aims to restore ...
Background: The GALERNA study is a retrospective real-world observational study conducted across 21 hospitals in Spain, aiming to evaluate long-term clinical benefits and adherence to benralizumab in 255 adult patients ...
INTRODUCTION: Despite growing international evidence supporting the effectiveness, safety, and efficiency of simultaneous bilateral total hip arthroplasty (BTHA), its adoption remains limited in Spain, where the sequential ...
INTRODUCTION: Despite growing international evidence supporting the effectiveness, safety, and efficiency of simultaneous bilateral total hip arthroplasty (BTHA), its adoption remains limited in Spain, where the sequential ...
Background: Work-related musculoskeletal disorders (WMSDs) are prevalent among orthopaedic surgeons as a result of prolonged exposure to non-neutral postures and forceful manual tasks during surgery. Although working height ...
BACKGROUND: The aim of this systematic review was to evaluate the impact of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) on medical complications, implant failure rates, and health-care-related costs in patients ...
INTRODUCTION: Endothelial dysfunction is key in COVID-19 pathogenesis. This randomized, double-blind phase IIb trial investigated continuous intravenous infusion of defibrotide in patients hospitalized with SARS-CoV-2 ...
PURPOSE: To compare 1-year best-corrected visual acuity (BCVA) after pars plana vitrectomy (PPV) for lamellar macular hole (LMH) between combined phacovitrectomy and sequential strategies, and to explore factors associated ...
BACKGROUND: Anatomopathological autopsy and postmortem genetic testing play a crucial role in forensic medicine, particularly in elucidating the causes of sudden death (SD) that remain unexplained by conventional methods. ...
INTRODUCTION: Migrants living with HIV often face high mobility, vulnerability and limited baseline information on HIV-1 genotype or treatment history. We aimed to assess the effectiveness and persistence of long-acting ...
BACKGROUND: Hepatitis C virus (HCV) has significantly impacted people with human immunodeficiency virus (HIV). Harm reduction programs, changing transmission patterns, and direct-acting antivirals (DAAs) have profoundly ...
AIMS: To analyse the impact of a participatory process of awareness and reflection on compassion, in the face of end-of-life processes, in students aged 12-23 years in six Spanish regions, and to understand how the ...