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Envíos recientes

02.01.01. Investigación y comunicación científica: Envíos recientes

  • Real-World Evidence on Joint Condition in Non-Severe Hemophilia A Patients: A Multicenter Study 
    Marco-Rico, Ana; Calvo-Villas, José-Manuel; López-Jaime, Francisco-José; Canaro-Hirnyk, María; Nieto-Hernández, María-del-Mar; Herrero-Martín, Sonia; Entrena-Urena, Laura; Marcellini-Antonio, Shally; Díaz-Jordan, Bolivar-L; Jurado-Herrera, Sergio; Pérez-González, Noelia-Florencia; García-Díaz, Covadonga; García-Candel, Faustino; Fernández-Bello, Ihosvany; Marco-Vera, Pascual (DOVE MEDICAL PRESS LTD, 2025-05)
    PURPOSE: Patients with non-severe hemophilia A (PwnSHA) may be at risk for joint damage (JD), yet data remain scarce. Our aim was to evaluate the joint condition in PwnSHA in a real-world setting. PATIENTS AND METHODS: A ...
  • Survival risk prediction in hematopoietic stem cell transplantation for multiple myeloma 
    Belmonte, José-María; Blanquer-Blanquer, Miguel; Bernabé, Gregorio; Jiménez, Fernando; García, José-Manuel (WALTER DE GRUYTER GMBH, 2025-10-30)
    This paper investigates the application of Survival Analysis (SA) techniques to forecast outcomes after autologous Hematopoietic Stem Cell Transplantation (aHSCT) for Multiple Myeloma (MM). By leveraging six SA models, we ...
  • Lack of association between loneliness, social isolation and inflammation in people living with HIV aged ?50 years: Results from the sub-study "No One Alone-Gesida Study" 
    Blanco, José-Ramón; Albendin-Iglesias, Helena; Negredo-Puigmal, Eugenia; Barrios-Blandino, Ana-María; Tomás-Jimenez, Cristina; Sanjoaquin-Conde, Isabel; Saumoy, María; Pérez-Esquerdo, Veronica; González-Cuello, Inmaculada; López-Lirola, Ana-María; Galindo, María-José; Cabello-Clotet, Noemi; Otero, Jesica-Abadia; Merino-Muñoz, Dolores; Cano-Smith, Joanna; Muelas-Fernández, Magdalena; de-la-Torre, Javier; González-Baeza, Alicia; Romero, Lourdes; Ocampo, Antonio; Torres, Rafael; Hidalgo, Carmen; Esteban, Herminia; Fernandes-López, María-Ángeles; Puig, Jordi; García-Fraile, Lucio; Bernal-Morell, Enrique; Pérez-Martínez, Laura; de-Miguel-Montero, Marta; Jarrin, Inma; Olalla, Julián (PUBLIC LIBRARY SCIENCE, 2025-12-17)
    Inflammation is linked to multiple health conditions. Emerging evidence suggest it may play a role in the association between social isolation - loneliness and health outcomes. People living with HIV (PLWH) exhibit chronic ...
  • Complications in cesarean sections: A national survey of obstetric protocols and outcomes in Spain 
    Cancelo-Hidalgo, María-Jesús; Blanco-Carnero, José-Eliseo; Cerrillos-González, Lucas (PUBLIC LIBRARY SCIENCE, 2025-09-03)
    INTRODUCTION: Cesarean sections are among the most common obstetric surgeries worldwide. While generally safe, they can be complicated by numerous factors increasing risks for both mother and fetus, and posing significant ...
  • Longitudinal biomarker progression and validation for predicting operational tolerance in a prospective multicenter liver transplantation immunosuppression withdrawal trial 
    López-Díaz, Gloria; Sánchez-Lorencio, María-Isabel; Inarrairaegui, Mercedes; González-Dieguez, María-Luisa; Cadahia, Valle; Otero-Ferreiro, Alejandra; Vázquez-Millan, María-Ángeles; Romero-Cristobal, Mario; Salcedo, Magdalena; Lorente-Pérez, Sara; Sánchez-Antolin, Gloria; de-la-Peña, Jesús; Ramírez, Pablo; Pata, María-P; Baroja-Mazo, Alberto; Herrero, José-I; Pons-Miñano, José-Antonio (PUBLIC LIBRARY SCIENCE, 2025-12-08)
    Liver transplantation (LT) is a life-saving treatment for end-stage liver disease, but long-term immunosuppression (IS) is associated with significant side effects. Achieving operational tolerance (OT), where the graft is ...
  • Impact of bictegravir/emtricitabine/tenofovir alafenamide on health-related quality of life and economic outcomes in HIV care: Substudy of the BIC-NOW clinical trial 
    Sequera-Arquelladas, Sergio; Vivancos, María-J; Vinuesa, David; Collado, Antonio; de-los-Santos, Ignacio; Sorni, Patricia; Cabello-Clotet, Noemi; Montero, Marta; Ramos-Font, Carlos; Terron, Alberto; Galindo, María-José; Martínez-Madrid, Onofre; Ryan, Pablo; Omar-Mohamed, Mohamed; Albendin-Iglesias, Helena; Javier, Rosario; Romero, Alberto; García-Vallecillos, Coral; Calleja, Miguel-Ángel; Hidalgo-Tenorio, Carmen (PUBLIC LIBRARY SCIENCE, 2025-09-22)
    BACKGROUND: The BICNOW clinical trial evaluated the effectiveness, safety, satisfaction, adherence to treatment, and retention in the system of a rapid initiation strategy with bictegravir/emtricitabine/tenofovir alafenamide ...
  • Index microvascular resistance (IMR) in heart transplant patients (IMR-HT study): Study protocol 
    Pérez-Guerrero, Ainhoa; Vilchez-Tschischke, Jean-Paul; Almenar-Bonet, Luis; Díez-Gil, José-Luis; Blasco-Peiro, Teresa; Brugaletta, Salvatore; Gómez-Lara, Josep; González-Costello, José; Antuna, Paula; Alonso-Fernández, Vanesa; Sarnago-Cebada, Fernando; García-Cosio, María-Dolores; Hidalgo-Lesmes, Francisco; López-Granados, Amador; López-Palop, Ramón; Garrido-Bravo, Iris-Paula; Cardenal-Piris, Rosa-María; Rangel-Sousa, Diego; Fuertes-Ferre, Georgina (PUBLIC LIBRARY SCIENCE, 2025-05-16)
    BACKGROUND: Acute allograft rejection (AAR) is an important cause of morbi mortality in heart transplant (HT) patients, particularly during the first year. Endomyocardial biopsy (EMB) is the "gold standard" to guide post- ...
  • Cardiac electrical abnormalities in a mouse model of left ventricular non-compaction cardiomyopathy 
    Fernandes, Vitor-S; Caballero, Ricardo; Siguero-Álvarez, Marcos; Papoutsi, Tania; Gimeno-Blanes, Juan-Ramón; Delpon, Eva; de-la-Pompa, José-Luis (PUBLIC LIBRARY SCIENCE, 2025-05-07)
    Mutations in MINDBOMB 1 (MIB1), encoding an E3 ubiquitin ligase of the NOTCH signaling pathway, cause left ventricular noncompaction cardiomyopathy (LVNC) in mice and humans, increasing the risk of arrhythmia and left ...
  • Prospective observational study of oral clonazepam to prevent high-dose busulfan-induced seizures in adult patients 
    Díaz-Carrasco, María-Sacramento; Sánchez-Salinas, Andrés; Fernández-Ávila, Juan-José; Olmos-Jiménez, Raquel; Español-Morales, Ignacio; Espuny-Miro, Alberto (SPRINGER, 2025-02-03)
    BACKGROUND: Busulfan at high doses has been associated with a risk of seizures. Phenytoin has been used traditionally as anti-seizure prophylaxis, and benzodiazepines and levetiracetam have been introduced more recently, ...
  • Existence and relevance of fulminant severe community-acquired pneumonia 
    Salton, Francesco; Villar, Jesús; Mondoni, Michele; Harari, Sergio; Salotti, Andrea; Ambros, Alfonso; Alba, Francisco; Ferrando, Carlos; Muñoz, Tomas; Soler, Juan-A; Pérez-Mendez, Lina; Fernández, Cristina; Martínez, Domingo; Gasparotto, Stefano; Centanni, Stefano; Zuccon, Umberto; Barbati, Giulia; Rocca, Andrea; Ruaro, Barbara; Confalonieri, Marco; Confalonieri, Paola (BMC, 2025-11-05)
    BACKGROUND: Severe community-acquired pneumonia (sCAP) is a major contributor to global hospital mortality, with some patients rapidly progressing to death within a few days due to acute respiratory distress syndrome (ARDS), ...
  • Probable chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids syndrome: management with corticosteroids and intravenous immunoglobulin-a case report 
    Encarnación-Navarro, Juan-Antonio; León-Hernández, Adelaida; Litrán-López, Guillermo; Alonso-Romero, José-Luis; de-la-Fuente-Muñoz, Isabel; Cárdenas-Cánovas, Enrique; Ruiz-Carreño, Paula; Royo-Villanova, Mario; Mansó-Murcia, Clara (BMC, 2025-07-17)
    BACKGROUND: Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids is a rare, subacute inflammatory disorder of the central nervous system with an unknown etiology. It is characterized ...
  • Gender differences in clinical and prescribing characteristics of biologic and targeted synthetic drugs in naïve patients with rheumatoid arthritis: Data from BIOBADASER III registry 
    Vela-Casasempere, Paloma; Otero-Varela, Lucía; Gómez-Sabater, Silvia; Alameda, Rocio-Cano; Campos-Fernández, Cristina; Calvo-Gutiérrez, Jerusalen; Pérez-Vera, Yanira; Manrique-Arija, Sara; Bustabad, Sagrario; Manero-Ruiz, Javier; Ruiz-Montesino, María-Dolores; Gutiérrez, Lucía-Ruiz; Mera-Varela, Antonio; Moreno-Ramos, Manuel-José; Sánchez-Alonso, Fernando; Castrejon, Isabel (BMC, 2025-05-14)
    BACKGROUND: Rheumatoid arthritis (RA) is a chronic systemic inflammatory autoimmune disease that can lead to progressive joint damage and irreversible disability when inadequately treated. RA is more common in women than ...
  • Disease activity in patients with idiopathic inflammatory myopathy according to time since diagnosis and positivity to antisynthetase autoantibodies: data from the Myo-Spain registry 
    Cobo-Ibáñez, Tatiana; Castellvi, Iván; Pros, Ana; Domínguez-Álvaro, Marta; Nuno-Nuno, Laura; Martínez-Barrio, Julia; Jovani, Vega; Romero-Bueno, Fredeswinda; Ruiz-Lucea, Esther; Tomero, Eva; Trallero-Araguas, Ernesto; Narváez, Javier; Camins-Fabregas, Jordi; Ruiz-Roman, Alberto; Loarce-Martos, Jesús; Holgado-Pérez, Susana; Flores-Rodríguez, V-Miguel; Sivera, Francisca; Merino-Argumanez, Carolina; Juan-Mas, Antonio; Altabas-González, Irene; Martín-López, María; Belzunegui-Otano, Joaquín-María; Carrasco-Cubero, Carmen; Freire-González, Mercedes; Rua-Figueroa, Íñigo-Jesús; Lozano-Rivas, Nuria; Suárez-Cuba, Julio-David; Martínez, Olga; Ortega-Castro, Rafaela; Alcocer, Patricia; Gómez-Gómez, Alejandro; Sánchez-Pernaute, Olga; Tandaipan, José-Luis; Carrion-Barbera, Irene; Plasencia-Rodríguez, Chamaida; Ibarguengoitia-Barrena, Oihane; Vidal-Montal, Paola; Ortiz-Santamaria, Vera; Garrido-Puñal, Noemi; Riveros, Anne; Delgado-Frias, Esmeralda; López-Gómez, Juan-Miguel; Barbadillo, Carmen; Pego-Reigosa, José-María; Joven-Ibáñez, Beatriz-E; Valero-Jaimes, Jesús-Alejandro; Naveda, Elena; Turrion-Nieves, Ana-Isabel; Seoane-Mato, Daniel; Prado-Galbarro, Francisco-Javier; Puche-Larrubia, M-angeles (BMC, 2025-01-08)
    OBJECTIVE: To evaluate the main outcomes of disease activity and their association with other measures of activity, damage, and quality of life in patients with idiopathic inflammatory myopathy (IIM) according to time since ...
  • Randomized clinical trial of the use of Propofol as a sedative agent versus spinal analgesia with bupivacaine in External Cephalic Version (PropoSpinECV): study protocol for a randomized clinical trial 
    Sánchez-Romero, Javier; Falcón-Arana, Luis; Blanco-Carnero, José-Eliseo; García-Fulgueiras, Ana; Herrera-Giménez, Javier; Fuentes-García, Diego; Araico-Rodríguez, Fernando; Gallego-Pozuelo, rosa-María; Nieto-Díaz, Anibal; de-Paco-Matallana, Catalina (BMC, 2025-10-09)
    BACKGROUND: External Cephalic Version (ECV) is an effective procedure for modifying fetal position to achieve a cephalic presentation. ECV is usually performed with tocolysis and spinal anesthesia. Recently, propofol has ...
  • Ipatasertib combined with non-taxane chemotherapy for patients with previously treated advanced triple-negative breast cancer: the PATHFINDER phase IIa trial 
    López-Miranda, Elena; Pérez-García, José-Manuel; Gion, María; Ribelles, Nuria; Cortez-Castedo, Patricia; Alonso-Romero, José-Luis; Martínez-García, María; González-Santiago, Santiago; Bermejo, Begoña; Morales, Serafin; Caranana, Vicente; Garrigos, Laia; Fernández-Pinto, Melissa; García-Vicente, Silvia; García-Sanz, Alicia; Mena-Molina, Arnau; Boix, Olga; Alcalá-López, Daniel; Llombart-Cussac, Antonio; Cortés, Javier (BMC, 2025-08-06)
    BACKGROUND: The PI3K/AKT pathway is frequently altered in advanced triple-negative breast cancer (aTNBC), representing a promising target. Ipatasertib, a pan-AKT inhibitor, has shown activity with taxane-based chemotherapy ...
  • Predictors and barriers to minimally adequate treatment among treated individuals with mental disorders: results from the World Mental Health Surveys. 
    Pozuelo, Julia-R; Vigo, Daniel-V; Kazdin, Alan-E; Harris, Meredith-G; Stein, Dan-J; Viana-Llamas, María-Carmen; Hwang, Irving; Kessler, Timothy-L; Manoukian, Sophie-M; Sampson, Nancy-A; Aguilar-Gaxiola, Sergio; Alonso, Jordi; Andrade, Laura-Helena; Ayinde, Olatunde-O; Bruffaerts, Ronny; Bunting, Brendan; Caldas-de-Almeida, José-Miguel; Chardoul, Stephanie; de-Girolamo, Giovanni; Domenech, Cristina; Gureje, Oye; Karam, Elie-G; Kiejna, Andrzej; Kovess-Masfety, Viviane; Medina-Mora, María-Elena; Moskalewicz, Jacek; Navarro-Mateu, Fernando; Nishi, Daisuke; Piazza, Marina; Posada-Villa, José; Scott, Kate-M; Ten-Have, Margreet; Torres, Yolanda; Vladescu, Cristian; Kessler, Ronald-C (BMC, 2025-12-18)
    BACKGROUND: Treatments for mental disorders vary widely in type and quality, with many patients failing to receive treatments that meet even minimally adequate standards. We use data from the World Mental Health (WMH) ...
  • Pathway to effective treatment for common mental and substance use disorders in the World Mental Health Surveys: Perceived need for treatment 
    Harris, Meredith-G; Kazdin, Alan-E; Hwang, Irving; Manoukian, Sophie-M; Sampson, Nancy-A; Stein, Dan-J; Viana-Llamas, María-Carmen; Vigo, Daniel-V; Alonso, Jordi; Andrade, Laura-Helena; Bruffaerts, Ronny; Bunting, Brendan; Caldas-de-Almeida, José-Miguel; Chardoul, Stephanie; de-Girolamo, Giovanni; Gureje, Oye; Haro, Josep-María; Karam, Elie-G; Kovess-Masfety, Viviane; Medina-Mora, María-Elena; Navarro-Mateu, Fernando; Nishi, Daisuke; Posada-Villa, José; Rapsey, Charlene; Stagnaro, Juan-Carlos; ten-Have, Margreet; Wciorka, Jacek; Zarkov, Zahari; Kessler, Ronald-C (BMC, 2025-05-23)
    BACKGROUND: Perceived need for treatment is a first step along the pathway to effective mental health treatment. Perceived need encompasses a person's recognition that they have a problem and their belief that professional ...
  • Management of sleep-disordered breathing in achondroplasia: guiding principles of the European Achondroplasia Forum 
    Fauroux, Brigitte; Alsayed, Moeenaldeen; Ben-Omran, Tawfeg; Boero, Silvio; Boon, Mieke; Cormier-Daire, Valerie; Fredwall, Svein; Guillén-Navarro, Encarna; Irving, Melita; Kunkel, Philip; Madureira, Nuria; Maghnie, Mohamad; Milerad, Josef; Mohnike, Klaus; Mortier, Geert; Nobili, Lino; Pejin, Zagorka; Sessa, Marco; Sousa, Sergio-B (BMC, 2025-05-15)
    Due to the craniofacial anatomy of people with achondroplasia, sleep-disordered breathing (SDB) occurs more frequently than in the average stature population. SDB, which comprises obstructive sleep apnoea (OSA), more rarely ...
  • Evolution of mobility, pain/discomfort, self-care, and mental health in patients with alpha-mannosidosis: an international caregiver and patient survey 
    Stepien, Karolina-M; Thomas, Sophie; Hennermann, Julia-B; Lampe, Christina; Muschol, Nicole-M; Ballesta-Martínez, María-Juliana; Cruz, Jordi; López-Rodríguez, Mónica; Barth, Anneliese; Magner, Martin; Lund, Allan-M; Plaiasu, Vasilica; Ballabeni, Andrea; Dona, Francesca; Morgan, Heather-M; Guffon, Nathalie (BMC, 2025-05-07)
    BACKGROUND: Alpha-mannosidosis is a rare recessive lysosomal storage disorder with progressive multi-systemic impacts. In the absence of standardized monitoring protocols, there is insufficient understanding of disease ...
  • Recommendations for management of infants and young children with achondroplasia: Does clinical practice align? 
    Guillén-Navarro, Encarna; Alsayed, Moeenaldeen; Alves, Inés; Ben-Omran, Tawfeg; Boero, Silvio; Cormier-Daire, Valerie; Fauroux, Brigitte; Fredwall, Svein; Irving, Melita; Kunkel, Philip; Lampe, Christian; Lausch, Ekkehart; Maghnie, Mohamad; Mohnike, Klaus; Mortier, Geert; Pejin, Zagorka; Sessa, Marco; Sousa, Sergio-B (BMC, 2025-03-11)
    BACKGROUND: Achondroplasia is one of the most prevalent forms of skeletal dysplasia. Lifelong follow-up by an experienced multidisciplinary team is required, particularly during the first 2 years. In 2021, international ...

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