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Envíos recientes

02.01.01. Investigación y comunicación científica: Envíos recientes

  • ApoJ and apoL1 as novel determinants of MASH: a cross-sectional study 
    Cai, Zichun; Najib, Souad; Núñez-Sánchez, María-Ángeles; Martínez-Sánchez, María-A; García-Melgares-Gil, Carmen; Viguerie, Nathalie; Rossell, Joana; Julve, Josep; Croyal, Mikael; Rodrigues-Oliveira, Arsenio; Martínez, Carlos-M; Dumas, Sebastien-J; Genoux, Annelise; Frutos-Bernal, María-Dolores; Ramos-Molina, Bruno; Martínez, Laurent-O (BMC, 2025-10-14)
    BACKGROUND: Plasma apolipoproteins are linked to cardiometabolic dysfunctions, but their potential as biomarkers for metabolic dysfunction-associated steatohepatitis (MASH) remains underexplored. METHODS: Plasma levels of ...
  • Textbook outcome in ovarian cancer and its impact on survival: comparative study 
    Carbonell-Morote, Silvia; Arjona-Sánchez, Álvaro; Cascales-Campos, Pedro-Antonio; González-Gil, Alida; Gómez-Dueñas, Gonzalo; Gil-Gómez, Elena; Caravaca-García, Iban; Aranaz, Veronica; Lacueva, Francisco-Javier; Ramia, José-Manuel (BMC, 2025-02-01)
    INTRODUCTION: Patients who achieve the textbook outcome (TO) present an uneventful postoperative course. Obtaining TO has also been related to better survival in oncological patients. Information about TO in patients with ...
  • Relation of the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio to residual risk in anticoagulated patients with atrial fibrillation: a report from the prospective Murcia AF Project III cohort 
    Soler-Espejo, Eva; Chen, Yang; Rivera-Caravaca, José-Miguel; Ramos-Bratos, María-Pilar; Esteve-Pastor, María-Asunción; Marín, Francisco; Roldán-Schilling, Vanessa; Lip, Gregory-Y-H (BMC, 2025-09-30)
    BACKGROUND: Atrial fibrillation (AF) confers a high risk of thromboembolism and cardiovascular events, which persists despite optimal oral anticoagulation (OAC). The non-high-density lipoprotein cholesterol (non-HDL-C) to ...
  • Remnant-to-LDL cholesterol discordance as a predictor of thromboembolic events in anticoagulated patients with atrial fibrillation: a report from the prospective Murcia AF project III (MAFP-III) cohort study 
    Soler-Espejo, Eva; Chen, Yang; Rivera-Caravaca, José-Miguel; Ramos-Bratos, María-Pilar; López-Gálvez, Raquel; Marín, Francisco; Roldán-Schilling, Vanessa; Lip, Gregory-Y-H (BMC, 2025-07-10)
    BACKGROUND: Remnant cholesterol (RC) has emerged as an independent contributor to residual cardiovascular risk, beyond low-density lipoprotein cholesterol (LDL-C). As atrial fibrillation (AF) is a common arrhythmia associated ...
  • Obsessive-compulsive disorder in the World Mental Health surveys 
    Stein, Dan-J; Ruscio, Ayelet-Meron; Altwaijri, Yasmin; Chiu, Wai-Tat; Sampson, Nancy-A; Aguilar-Gaxiola, Sergio; Al-Hamzawi, Ali; Alonso, Jordi; Chardoul, Stephanie; Gureje, Oye; Hu, Chiyi; Karam, Elie-G; Mcgrath, John-J; Navarro-Mateu, Fernando; Scott, Kate-M; Stagnaro, Juan-Carlos; Torres, Yolanda; Vladescu, Cristian; Wciorka, Jacek; Xavier, Miguel; Kessler, Ronald-C (BMC, 2025-07-09)
    BACKGROUND: National surveys have suggested that obsessive-compulsive disorder (OCD) is a prevalent and impairing condition. However, there are few cross-national data on OCD, with data particularly scarce in low- and ...
  • Cost-utility analysis of dapagliflozin for the treatment of symptomatic chronic heart failure in Spain 
    Escobar, Carlos; Pascual-Figal, Domingo-Andrés; Guiu-Segura, Josep-María; Capel, Margarita; Pomares-Mallol, Elisenda; Caudron, Christian (BMC, 2025-07-24)
    BACKGROUND: The objective of this study was to perform a cost-utility analysis of dapagliflozin, as an add-on therapy to standard of care (SoC), compared with SoC, for patients with symptomatic chronic heart failure (HF) ...
  • Economic burden of secondary progressive multiple sclerosis: DISCOVER study 
    Oreja-Guevara, Celia; Meca-Lallana, José-Eustasio; Gómez-Estevez, Irene; Ara, José-Ramón; Hernández-Pérez, Miguel-Ángel; Gil, Julia-Gracia; Alonso-Torres, Ana-María; Pilo-de-la-Fuente, Belén; Ramio-Torrenta, Lluis; Eichau-Madueño, Sara; Gascon-Giménez, Francisco; Casanova, Bonaventura; Martínez-Yelamos, Sergio; Aguado-Valcárcel, Marta; Martínez-Gines, María-Luisa; Montero, Yasmina-El-Berdei; López-Real, Ana-María; González-Quintanilla, Vicente; López-de-Silanes, Carlos; Martínez-Rodríguez, José-Enrique; Costa-Frossard, Lucienne; Garcés-Redondo, M; Labiano-Fontcuberta, Andrés; Castellanos-Pinedo, Fernando; García-Merino, Juan-Antonio; Muñoz-Fernández, Carmen; Castillo-Trivino, Tamara; Meca-Lallana, Virginia; Peña-Martínez, Joaquín; Rodríguez-Antiguedad, Alfredo; Prieto-González, José-María; Agüera-Morales, Eduardo; Pérez-Molina, Inmaculada; Solar-Sánchez, Dulce-M; Herrera-Varo, Nicolás; Aguirre-Vázquez, Marta; Rodríguez-Barrios, José-Manuel; Rio, Jordi (BMC, 2025-04-10)
    BACKGROUND: To estimate the socioeconomic burden of people with secondary progressive multiple sclerosis (pwSPMS), considering direct health care, direct non-health care, and indirect costs, and to evaluate the relationship ...
  • Final analysis of ArtemisR, a European real-world retrospective study of apalutamide for the treatment of patients with metastatic hormone-sensitive prostate cancer 
    Boegemann, Martin; Bennamoun, Mostefa; Dourthe, Louis-Marie; Encarnación-Navarro, Juan-Antonio; Hegele, Axel; Hellmis, Eva; Latorzeff, Igor; Leicht, Wolfgang; Oñate-Celdrán, Julián; Rosino-Sánchez, Antonio; Hanna, Krystelle; Lencart, Joana; Lukac, Martin; Schioppa, Claudio-A; Van-Sanden, Suzy; Kramer, Gero (BMC, 2025-07-01)
    BACKGROUND: We examined real-world outcomes of patients with metastatic hormone-sensitive prostate cancer (mHSPC) treated with apalutamide plus androgen deprivation therapy (ADT). The current study, reflecting real-life ...
  • AEOL-induced NRF2 activation and DWORF overexpression mitigate myocardial I/R injury 
    Asensio-López, María-del-Carmen; Ruiz-Ballester, Miriam; Pascual-Oliver, Silvia; Bastida-Nicolás, Francisco-José; Sassi, Yassine; Fuster, José-Javier; Pascual-Figal, Domingo-Andrés; Soler, Fernando; Lax, Antonio (SPRINGER, 2025-05-15)
    BACKGROUND: The causal relationship between the activation of nuclear factor erythroid 2-related factor 2 (NRF2) and the preservation of SERCA2a function in mitigating myocardial ischemia-reperfusion (mI/R) injury, along ...
  • Impact of environmental exposures on exhaled breath and lung function: NELA Birth Cohort 
    Sola-Martínez, Rosa-Alba; Jiménez-Guerrero, Pedro; Sánchez-Solís, Manuel; Lozano-Terol, Gema; Gallego-Jara, Julia; Martínez-Vivancos, Adrián; Morales, Eva; García-Marcos, Luis; de-Diego-Puente, Teresa (EUROPEAN RESPIRATORY SOC JOURNALS LTD, 2025-01)
    INTRODUCTION: Exposure to environmental factors (i.e. air pollution and second-hand tobacco smoke) have been associated with impaired lung function. However, the impact of environmental factors on lung health is usually ...
  • Autologous stem cell transplantation for relapsed/refractory large B-cell lymphoma: a multicenter GETH-TC/GELTAMO study 
    Bento, Leyre; Gutiérrez, Antonio; Martínez, Carmen; Orti-Verdet, María-Consejo; Sorribes, Marina; Caballero, Ana-Carolina; Peña, Marta; Pérez, Ariadna; Jiménez-Ubieto, Ana; Medina, Lucía; Bastos-Oreiro, Mariana; Fernández-Caldas-González, Paula; Navarro, Belén; Salcedo, Isabel; Abrisqueta, Pau; Español-Morales, Ignacio; Cornago, Javier; Martín-Moro, Fernando; García, Lucía; Gómez, Pilar; Varela, María-Rosario; Puente, María; Zanabili, Joud; Zudaire, Teresa; Zeberio, Izaskun; del-Campo, Raquel; González, Leslie; González, Pedro; Blázquez, Cristina; Rovira, Jordina; Sitges, Marta; Franch-Sarto, Mireia; Cabero, Almudena; Mussetti, Alberto; Montoro, Juan; Sampol, Antonia; Sureda, Anna; Caballero, Dolores; Martín-García-Sancho, Alejandro (ELSEVIER, 2025-07-08)
    We performed a retrospective multicenter study including 791 patients with relapsed/refractory (R/R) large B-cell lymphoma (LBCL) who underwent autologous stem cell transplantation (ASCT). After a median follow-up of 74 ...
  • Clinical impact of [18F]FDG-PET/CT in ARI0002h treatment, a CAR-T against BCMA for relapsed/refractory multiple myeloma 
    Zugas, Inés; Tormo-Ratera, Marta; Oliver-Caldes, Aina; Soler-Perromat, Juan-Carlos; González-Calle, Veronica; Moreno, David-F; Cabanas-Perianes, Valentín; López-Muñoz, Nieves; Bartolome-Solanas, Álvaro; Español-Rego, Marta; Reguera-Ortega, Juan-Luis; Rosinol, Laura; López-Corral, Lucía; Tovar, Natalia; Rodríguez-Lobato, Luis-Gerardo; Álvarez-Pérez, Rosa-María; Varea, Sara; Olesti, Eulalia; Gómez-Grande, Adolfo; Frutos-Esteban, Laura; Tamayo, Pilar; Juan, Manel; Moraleda-Jiménez, José-María; Urbano-Ispizua, Álvaro; González-Navarro, Europa-Azucena; Martínez-López, Joaquín; Mateos, María-Victoria; Tomas, Xavier; Setoain, Xavier; Fernández-de-Larrea, Carlos (ELSEVIER, 2025-02-11)
    Multiple myeloma (MM) remains incurable, with poor outcomes in heavily pretreated patients. Chimeric antigen receptor (CAR) T-cell therapy has emerged as a promising treatment; however, outcomes after such therapy in ...
  • Real-world data on spinal muscular atrophy in Spain: Insights from over 500 individuals in the CuidAME project 
    Puig-Ram, Cristina; Segovia, Sonia; García-Uzquiano, Rocío; Nungo-Garzón, Nancy-Carolina; Aragon-Gawinska, Karolina; García-Romero, Mar; Exposito-Escudero, Jesica-María; Carrera-García, Laura; López-Lobato, Mercedes; Paradas, Carmen; González-Mera, Laura; Molinero, Mireia-Alvarez; Gómez-Andrés, David; Toro, Esther; Fernández-Ramos, Joaquín-Alejandro; Grimalt, María-Antonia; Toledo-Bravo-de-Laguna, Laura; González-Barrios, Desire; Tizzano, Eduardo-F; Cattinari, María-Grazia; Medina, Julita; Calvo-Medina, Rocío; Munell, Francina; Sotoca, Javier; Martínez-Salcedo, Eduardo; Moreno-Escribano, Antonio; Povedano-Panades, Mónica; Fernández-García, Miguel-A; Pitarch-Castellano, Inmaculada; Vázquez-Costa, Juan-F; Natera-de-Benito, Daniel; Nascimento, Andrés (SAGE PUBLICATIONS INC, 2025-11)
    BackgroundThe new treatment paradigm in Spinal Muscular Atrophy (SMA) has introduced novel phenotypes, changes in trajectories and clinical questions not fully addressed in clinical trials. To explore these challenges, ...
  • Observational retrospective study of the treatment of Waldenström's macroglobulinemia with ibrutinib in routine clinical practice in Spain 
    Fernández-de-Larrea, Carlos; Loscertales, Javier; Cabanas-Perianes, Valentín; Freiria, Carmen; Blanchard, María-Jesús; Askari, Elham; Lorenzo-Pérez, Marcos; Abril-Parreño, Laura; López-Pardo, Jordi; Pinzón, Sergio; Díaz-Galvez, Javier; Amer, Neus; Ramírez-Payer, Ángel; García-Sánchez, Ricarda; Alcalá, María-Magdalena; Capote, Francisco-Javier; Moreno, David; Bolumburu, Celia; Rubio-Azpeitia, Eva; García-Sanz, Ramón (SAGE PUBLICATIONS LTD, 2025-07)
  • How do neurologists perceive the organization and functioning of multiple sclerosis care units? 
    Landete, Lamberto; Gómez-Ballesteros, Rocío; Meca-Lallana, Virginia; Caminero, Ana-B; Meca-Lallana, José-Eustasio; Martínez-Yelamos, Sergio; García-Domínguez, José-M; Agüera, Eduardo; García-Arcelay, Elena; Medrano, Nicolás; Villar, Luisa-M; Monreal, Enric; Maurino, Jorge (SAGE PUBLICATIONS INC, 2025-10)
    This study assessed how neurologists perceive the organization and functioning of multiple sclerosis care units. As a cross-sectional, observational study conducted in collaboration with the Spanish Society of Neurology, ...
  • Cost Analysis of the FreeStyle Libre Systems in People with Type 2 Diabetes Mellitus on Basal Insulin with Poor Glycemic Control: A Spanish Perspective 
    Ampudia-Blasco, Francisco-Javier; de-la-Cuadra-Grande, Alberto; Bellido, Virginia; Cebrián-Cuenca, Ana-María; Mezquita-Raya, Pedro; Carretero-Gómez, Juana; Hernández-Martínez, Antonio-Miguel; Oyaguez, Itziar; Gómez-Peralta, Fernando (MARY ANN LIEBERT, INC, 2026-01)
    Background and Aims: FreeStyle Libre® systems are effective and convenient glucose flash monitoring (FM) devices. This cost analysis compared FM versus self-monitoring of blood glucose (SMBG) in poorly controlled (glycated ...
  • Four years on: Pregnancy and birth outcomes reported in the MSBase pregnancy, neonatal outcomes, and Women's Health Registry (2020-2024) 
    Jokubaitis, Vilija-G; Alroughani, Raed; Altintas, Ayse; Eichau, Sara; Hughes, Stella; Willekens, Barbara; Horakova, Dana; Kubala-Havrdova, Eva; Ozakbas, Serkan; Boz, Cavit; Habek, Mario; Kalincik, Tomas; Roos, Izanne; Etemadifar, Masoud; Peterka, Marek; Lechner-Scott, Jeannette; Meca-Lallana, José-Eustasio; Rous, Zuzana; Houskova, Jana; Prat, Alexandre; Girard, Marc; Ampapa, Radek; Buzzard, Katherine; Skibina, Olga; John, Nevin-A; Kermode, Allan-G; Fabis-Pedrini, Marzena-J; Foschi, Matteo; Surcinelli, Andrea; Blanco, Yolanda; Baghbanian, Seyed-Mohammad; Gerlach, Oliver; Macdonell, Richard; Pavelek, Zbysek; Stourac, Pavel; McCombe, Pamela; Laureys, Guy; Butzkueven, Helmut; van-der-Walt, Anneke; Gray, Orla (SAGE PUBLICATIONS LTD, 2025-08)
    BACKGROUND: Family planning is an important aspect of multiple sclerosis (MS), and neuromyelitis optica spectrum disorder (NMOSD) management. Knowledge gaps remain, including optimal perinatal management strategies, and ...
  • Advancing Chrononutrition for Cardiometabolic Health: A 2023 National Heart, Lung, and Blood Institute Workshop Report 
    Dashti, Hassan-S; Jansen, Erica-C; Zuraikat, Faris-M; Dixit, Shilpy; Brown, Marishka; Laposky, Aaron; Broussard, Josiane-L; Butler, Matthew-P; Creasy, Seth-A; Crispim, Cibele-A; Depner, Christopher-M; Esser, Karyn-A; Garaulet, Marta; Hanlon, Erin-C; Makarem, Nour; Manoogian, Emily-N-C; Peterson, Courtney-M; Scheer, Frank-A-J-L; Wright-Jr, Kenneth-P; Goff, David-C; Pratt, Charlotte-A; Gamble, Karen-L; St-Onge, Marie-Pierre (WILEY, 2025-05-06)
    The circadian system maintains optimal biological functions at the appropriate time of day, and the disruption of this organization can contribute to the pathogenesis of cardiometabolic disorders. The timing of eating is ...
  • Redefining the Genetic Architecture of Hypertrophic Cardiomyopathy: Role of Intermediate-Effect Variants 
    García-Hernández, Soledad; de-la-Higuera-Romero, Luis; Fernández, Adrián; Pena-Pena, María-Luisa; Mora-Ayestaran, Nerea; Basurte-Elorz, María-Teresa; Larrañaga-Moreira, José-María; Cardenas-Reyes, Ivonne; Villacorta, Eduardo; Valverde-Gómez, María; Baustista-Paves, Alicia; Veira-Villanueva, Elena; Ortiz-Genga, Martin; Lipov, Alex; Brogger, Noel; Sabater-Molina, María; Moreno-Escobar, Eduardo; Ruiz-Guerrero, Luis; Syrris, Petros; Fernández, Xusto; Piqueras-Flores, Jesús; Amor-Salamanca, Almudena; Bezzina, Connie-R; Elliott, Perry-M; Barriales-Villa, Roberto; Gimeno-Blanes, Juan-Ramón; García-Pavia, Pablo; Walsh, Roddy; Ochoa, Juan-Pablo (LIPPINCOTT WILLIAMS & WILKINS, 2025-10-14)
    BACKGROUND: Hypertrophic cardiomyopathy (HCM) is a genetically heterogeneous disorder linked primarily to rare variants in sarcomeric genes, although recently certain nonsarcomeric genes have emerged as important contributors. ...
  • Chemical Optimization of Cerebral Embolectomy 2 (CHOICE 2) trial: study protocol 
    Renu, Arturo; de-la-Riva, Patricia; Delgado-Mederos, Raquel; Dorado, Laura; Fernández-Couto, María-Dolores; Herrera-Isasi, María; López-Hernández, Nicolas; Morales, Ana; Morales-Caba, Lluis; Camps-renom, Pol; Singla, Alba; Terceno, Mikel; Vega, Pedro; Amaro, Sergio; Blasco, Jordi; Laredo, Carlos; Leira, Enrique-C; Oleaga, Laura; Serena, Joaquín; Urra, Xabier; Werner, Mariano; Hernández-Fernández, Francisco; Valls, Joan; Arenillas-Lara, Juan-Francisco; Freijo, María-Del-Mar; Pérez-de-la-Ossa, Natalia; San-Roman, Luis; Torres, Ferran; Castellanos, Mar; Davalos, Antonio; Chamorro, Ángel (BMJ PUBLISHING GROUP, 2025-12-03)
    RATIONALE: The potential value of rescue intra-arterial thrombolysis in patients with large vessel occlusion (LVO) stroke treated with mechanical thrombectomy (MT) remains to be validated in randomised trials. AIM: The ...

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