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Envíos recientes

02.01.01. Investigación y comunicación científica: Envíos recientes

  • Non-Invasive Redox Biomarkers Detected in Organ Preservation Outflow Solution Enable Early Prediction of Human Liver Allograft Dysfunction 
    Vidal-Correoso, Daniel; Caballero-Herrero, María-José; Muñoz-Morales, Ana-M; Mateo, Sandra-V; Jover-Aguilar, Marta; Alconchel-Gago, Felipe; Martínez-Alarcón, Laura; López-López, Víctor; Ríos-Zambudio, Antonio; Cascales-Campos, Pedro-Antonio; Pons-Miñano, José-Antonio; Ramírez, Pablo; Stromsnes, Kristine; Gambini, Juan; Cuevas, Santiago; Baroja-Mazo, Alberto (MDPI, 2025-09-10)
    Liver transplantation is commonly used for end-stage liver disease, but the demand for organs exceeds the supply, leading to the use of expanded criteria donors (ECDs). Organs from ECDs, especially from donors after ...
  • Uric Acid and Preeclampsia: Pathophysiological Interactions and the Emerging Role of Inflammasome Activation 
    Arias-Sánchez, Celia; Pérez-Olmos, Antonio; Reverte-Ribo, Virginia; Hernández, Isabel; Cuevas, Santiago; Llinas-Mas, María-Teresa (MDPI, 2025-07-29)
    Preeclampsia (PE) is a multifactorial hypertensive disorder unique to pregnancy and a leading cause of maternal and fetal morbidity and mortality worldwide. Its pathogenesis involves placental dysfunction and an exaggerated ...
  • Cardioprotective Peptides from Dry-Cured Ham in Primary Endothelial Cells and Human Plasma: An Omics Approach 
    Noguera-Navarro, Clara; Stelling, Javier; Orenes-Piñero, Esteban; Pipino, Caterina; Nicolás, Francisco-José; Montoro-García, Silvia (MDPI, 2025-06-24)
    Cardiovascular diseases are a leading cause of mortality, driving the search for alternative preventive strategies. This study investigates the antioxidant effects, among others, of a mixture of four bioactive peptides ...
  • Inflammasomes in Alzheimer's Progression: Nrf2 as a Preventive Target 
    López-Hernández, Rubén; de-la-Torre-Álamo, María-Magdalena; García-Bueno, Belén; Baroja-Mazo, Alberto; Fenoy, Francisco-José; Cuevas, Santiago (MDPI, 2025-01-21)
    Current knowledge about Alzheimer's disease highlights the accumulation of ?-amyloid plaques (A?1-42) and neurofibrillary tangles composed of hyperphosphorylated Tau, which lead to the loss of neuronal connections. Microglial ...
  • Vaginal Administration of Progesterone in Twin Gestation: Influence on Bone Turnover and Oxidative Stress 
    Puche-Juarez, María; Toledano, Juan-M; Moreno-Fernández, Jorge; Díaz-Castro, Javier; Sánchez-Romero, Javier; Mar-Gil, María; Rolle, Valeria; Nieto-Díaz, Anibal; Ochoa, Julio-J; de-Paco-Matallana, Catalina (MDPI, 2025-03-08)
    Twin pregnancies, with higher incidences of preterm birth, are becoming more prevalent. Progesterone has shown effectiveness in the prevention of preterm labour, though other factors related to pregnancy and neonatal health ...
  • Influence and Role of Regulatory B Cells in Organ Transplantation: The State of the Art, Prospects, and Emerging Insights 
    Fernández-González, Marina; Llorente-Vinas, Santiago; Galián, José-Antonio; Botella-Martínez, Carmen; González-López, Rosana; Alegría-Marcos, María-José; Hita-Ruiz, Alicia; Moya-Quiles, María-Rosa; Martínez-Banaclocha, Helios; Muro-Pérez, Manuel; Muro, Javier; Minguela-Puras, Alfredo; Legaz, Isabel; Muro-Amador, Manuel (MDPI, 2025-11-07)
    B cells have attracted increasing interest in the field of organ transplantation due to their newly discovered immunoregulatory properties in alloimmune responses. Traditionally, B cells have been primarily associated with ...
  • Protocol for the ELISPOT-TC Trial: A Randomized Controlled Study Evaluating CMV-Specific Cellular Immune Monitoring in Heart Transplant Recipients 
    García-Romero, Elena; Diez-López, Carles; Kervella, Delphine; Donoso, Victor; García-Cosio, María-Dolores; Ortiz-Bautista, Carlos; Hernández-Pérez, Francisco-José; Couto-Mallon, David; González-Vilchez, Francisco; de-la-Fuente-galan, Luis; López-López, Laura; Grande-Trillo, Antonio; Gómez-Molina, Miriam; Catalá, Pablo; Herrador, Lorena; Rosenfeld, Laia; Ibáñez, Silvia; Donadeu, Laura; Sabe, Nuria; Comin-Colet, Josep; Bestard, Oriol; González-Costello, José (FRONTIERS MEDIA SA, 2025-11-27)
  • Nature-based interventions reduce physiological stress in children with chronic illnesses: evidence from salivary biomarkers 
    Díaz-Martínez, Francisco; Sanchez-Sauco, Miguel-Felipe; Orenes-Piñero, Esteban; Hernandez-Vera, María-José; Robledano-Aymerich, Francisco; Claudio, Luz; Ortega-García, Juan-Antonio (FRONTIERS MEDIA SA, 2025-12-11)
    INTRODUCTION: Contact with nature is increasingly recognized as an important determinant of public health, yet limited objective evidence exists regarding its benefits for children with chronic illnesses. This study aimed ...
  • Real-life evidence of encorafenib plus binimetinib in patients with unresectable advanced or metastatic BRAFV600-mutant melanoma in Spain: the BECARE (GEM-2002) trial 
    Soria, Ainara; Sánchez-Maurino, Pedro; Serrano-Domingo, Juan-José; García-Galindo, Regina; Sequero, Silvia; Gutiérrez-Sanz, Lourdes; Crespo, Guillermo; Díaz-Beveridge, Roberto; Puertolas, Teresa; López, Pedro; Rodríguez, Joaquín-Fra; López-Castro, Rafael; Aguayo, Cristina; Valdivia, Javier; Cunquero-Tomas, Alberto-Jacobo; Benítez, Gretel; Ayala-de-Miguel, Pablo; Espinosa, Enrique; Muñoz-Couselo, Eva; Campos, Begoña; García-Sánchez, Lourdes; Cerezuela-Fuentes, Pablo (FRONTIERS MEDIA SA, 2025-02-26)
    PURPOSE: Combined BRAF/MEK inhibition with encorafenib (E) plus binimetinib (B) has demonstrated efficacy and tolerability in phase III clinical trials, and is the standard of care for advanced/metastatic BRAF(V600)-mutant ...
  • Addressing common biases in the evaluation of lifetime alcohol consumption patterns and dementia risk: the EPIC-Spain dementia cohort 
    Huerta-Castaño, José-María; Colorado-Yohar, Sandra; Andreu-Reinón, María-Encarnación; Mokoroa, Olatz; Tainta, Mikel; Guevara, Marcela; Gasque, Alba; Castilla, Jesús; Petrova, Dafina; Crous-Bou, Marta; Zamora-Ros, Raúl; Sánchez, María-José; Chirlaque-López, María-Dolores (FRONTIERS MEDIA SA, 2025-10-14)
    BACKGROUND: Alcohol consumption has been described to exhibit a J-shaped relationship with dementia risk, but previous observations may be partly biased due to "sick-quitters" and competing risks of death. OBJECTIVE: To ...
  • Listening effort and stress in tinnitus: a multidimensional approach 
    Giliberto, Giovanna; Itati-Palacio, María; Cartocci, Giulia; Fernández-Villalba, Emiliano; Rossi, Dario; Mínguez-Merlos, Nieves; Botia, María; Cubillana-Herrero, José-Domingo; Ceron, José-Joaquín; Babiloni, Fabio; Herrero, María-Trinidad (FRONTIERS MEDIA SA, 2025-07-07)
    INTRODUCTION: This study investigated the impact of chronic tinnitus on auditory perception, text comprehension, and physiological stress responses, with a focus on sex-related differences. The main objectives were to ...
  • Study protocol for design of a personalized dietary supplement based on the gut microbiota of Alzheimer's patients and evaluation of its effects in a pilot randomized controlled trial 
    Clemente-Velasco, Sara; de-Lucas, Beatriz; Tabone, Mariangela; Bressa, Carlo; González-Soltero, María-del-Rocio; Martínez-López, Sara; Bailen, María; Domínguez-Balmaseda, Diego; Castellanos, Nazareth; Díez, Gustavo-G; Noguera-Perea, María-Fuensanta; Marín-Muñoz, Juan; Sánchez-Alonso, Pilar; Rey, Ana-Isabel; Galvez, Beatriz-G; Larrosa, Mar (FRONTIERS MEDIA SA, 2025-09-23)
    BACKGROUND: Increasing evidence links gut microbiota composition to neurological disorders, including Alzheimer's disease (AD), through the gut-brain axis. Microbial metabolites such as lipopolysaccharide (LPS) and butyrate ...
  • Multi-neuromeric origin of tyrosine hydroxylase-positive neurons within the substantia nigra and ventral tegmental area 
    Ferrán, José-Luis; Lucero-Arteaga, Franco; Ayad, Abdelmalik; Kutsenko, Yevheniy; Alonso, A; Ribeiro-Do-Couto, B; García-Cabezas, M-a; Tseng, Kuei-Y (FRONTIERS MEDIA SA, 2025-05-30)
    During early developmental stages, the brain is divided into three primary regions: the forebrain (prosencephalon), the hindbrain (rhombencephalon), and the spinal cord. These regions are further segmented into transverse ...
  • Macrophage activation syndrome-like in multiple myeloma patients treated with the academic CAR-T against BCMA ARI0002h 
    Munarriz, Daniel; Rodríguez-Lobato, Luis-Gerardo; López-Corral, Lucía; Arnaldos-Pérez, Cristina; Cabanas-Perianes, Valentín; López-Muñoz, Nieves; Oliver-Caldes, Aina; Ponce, Juan-Carlos; Reguera, Juan-Luis; Martin, Ana-Africa; Martínez-Cibrian, Nuria; Tovar, Natalia; Delgado, Julio; Guillen, Elena; Varea, Sara; Rodríguez-Otero, Paula; Urbano-Ispizua, Álvaro; Moraleda-Jiménez, José-María; Martínez-López, Joaquín; Mateos, María-Victoria; González-de-la-Calle, Veronica; González-Navarro, Europa-Azucena; Fernández-de-Larrea, Carlos (FRONTIERS MEDIA SA, 2025-10-16)
    BACKGROUND: Chimeric antigen receptor T-cell (CAR-T) therapy targeting B-cell maturation antigen (BCMA) has revolutionized multiple myeloma treatment (MM). However, managing its immune-mediated adverse events, particularly ...
  • Unveiling altered CD8 T-cell metabolism and homeostatic proliferation behind a low CD4/CD8 ratio in ART-suppressed HIV individuals with normal CD4 recovery 
    Garrido-Rodríguez, Vanesa; Bulnes-Ramos, Ángel; Olivas-Martínez, Israel; Pozo-Balado, María-del-Mar; Tejerina-Picado, Francisco; Gutiérrez, Felix; Marco-Sánchez, Cristina; Tiraboschi, Juan-Manuel; Castillo-Navarro, Antonia-María; Bernal-Morell, Enrique; García-Guerrero, María-C; Puertas, María-C; Peraire, Joaquim; Rull, Anna; Martínez-Picado, Javier; Pacheco, Yolanda-María; CoRIS-Cohort (FRONTIERS MEDIA SA, 2025-09-08)
    BACKGROUND: People living with chronic HIV (PLWH) show immune dysfunction, despite viral suppression and normal CD4 recovery, particularly those with low CD4/CD8 ratios. Subjacent cellular alterations of such a reliable ...
  • A zebrafish model of Ifih1-driven Aicardi-Goutières syndrome reproduces the interferon signature and the exacerbated inflammation of patients (vol 14, 1294766, 2023) 
    Bernal-Bermúdez, Beatriz; Martínez-López, Alicia; Martínez-Morcillo, Francisco-J; Tyrkalska, Sylwia-D; Martínez-Menchón, Teresa; Mesa-del-Castillo, Pablo; Cayuela-Fuentes, María-Luisa; Mulero, Víctoriano; García-Moreno, Diana (FRONTIERS MEDIA SA, 2025-01-06)
    [This corrects the article DOI: 10.3389/fimmu.2023.1294766.].
  • Frailty assessment in adults undergoing allogeneic hematopoietic cell transplantation: insights from a multicenter GETH-TC study to optimize outcomes and care 
    Queralt-Salas, María; Solano, María-Teresa; Baile-González, Mónica; Acera-Gómez, Marina; Fox, Laura; Pérez-Artigas, María-del-Mar; Santamaria, Ana; Quintela-González, María-del-Carmen; Sánchez-Salinas, Andrés; Salmerón-Camacho, Joaquina-María; Illana-alvaro, Veronica; Abdallahi-Lefdil, Zahra; Cornago-Navascues, Javier; Pardo, Laura; Fernández-Luis, Sara; Vega-Suárez, Leddy-Patricia; Villar, Sara; Beorlegui-Murillo, Patricia; Esquirol, Albert; Izquierdo-García, Isabel; Rodríguez-González, Sonia; Mussetti, Alberto; Lavilla-Rubira, Esperanza; López-Marín, Javier; Filaferro, Silvia; Cedillo, Ángel; Bento, Leyre; Sureda, Anna (FRONTIERS MEDIA SA, 2025-01-07)
    INTRODUCTION: This multicenter prospective study sponsored by the Grupo Español de Transplante Hematopoyético y Terapia Celular (GETH-TC) explores the use of frailty assessments in allo-HCT candidates. METHODS: Frailty was ...
  • Interplay of KIR2DL5, nitric oxide, and tobacco smoking in predisposition to bladder cancer 
    Ruiz-Lorente, Inmaculada; Gimeno-Arias, Lourdes; López-Abad, Alicia; López-Cubillana, Pedro; Fernández-Aparicio, Tomás; Asensio-Egea, Lucas-Jesús; Moreno-Avilés, Juan; Doñate-Íñiguez, Gloria; Guzmán-Martínez-Valls, Pablo-Luis; Server, Gerardo; Ferri-Ñíguez, Belén; Campillo, José-Antonio; Galindo, Francisco; Boix-Giner, Francisco; Martínez-Sánchez, María-Victoria; Martínez-Hernández, María-Dolores; Minguela-Puras, Alfredo (FRONTIERS MEDIA SA, 2025-09-04)
    INTRODUCTION: Tobacco smoking is the most significant risk factor for bladder cancer (BC), followed by other environmental and dietary exposures. However, major genetic determinants remain unidentified. The objective of ...
  • Effectiveness of a training program in the approach to gender-based violence in emergency professionals: A quasi-experimental study 
    Adánez-Martínez, Gracia; Pérez-Cánovas, Carlos; Leal-Costa, César; Conesa-Ferrer, María-Belén; Díaz-Agea, José-Luis; Jiménez-Ruiz, Ismael (GOBIERNO DE NAVARRA, 2025-04-22)
    BACKGROUND: Health systems play a key role in the detection and management of gender-based violence. This study aimed to evaluate the effectiveness of a training program designed to enhance the knowledge, skills, and ...
  • Neurologists' Openness to Evidence-Based Innovation in Multiple Sclerosis Care: Individual and Structural Determinants 
    Monreal, Enric; Gómez-Ballesteros, Rocío; Meca-Lallana, Virginia; Caminero, Ana-B; Meca-Lallana, José-Eustasio; Martínez-Yelamos, Sergio; Landete, Lamberto; García-Domínguez, José-M; Agüera, Eduardo; García-Arcelay, Elena; Medrano, Nicolás; Villar, Luisa-M; Maurino, Jorge (DOVE MEDICAL PRESS LTD, 2025-07)
    PURPOSE: Integration of evidence-based innovations, such as serum neurofilament light chain (sNfL) measurement into routine practice represents a pivotal opportunity to advance personalized care in multiple sclerosis (MS) ...

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