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Envíos recientes

02.01.01. Investigación y comunicación científica: Envíos recientes

  • Bone Health in Metastatic Hormone-Sensitive Prostate Cancer: Where We Stand and Where We Can Improve 
    Encarnación-Navarro, Juan-Antonio; López-Jiménez, Enrique; Alonso-Romero, José-Luis; Ruiz-Carreño, Paula; Ros-Martínez, Silverio; de-la-Fuente-Muñoz, Isabel; López, Francisco; Cárdenas-Cánovas, Enrique; Laborda-Segovia, Ana; Sánchez-Pérez, Marta; Rodríguez, Cristina; Mansó-Murcia, Clara; Ortega-López, Nicolás-Darío; López-Cubillana, Pedro; Guzmán-Martínez-Valls, Pablo-Luis; Cao-Avellaneda, Enrique; López-González, Pedro-Ángel; López-Abad, Alicia (MDPI, 2025-12-13)
    BACKGROUND: Androgen deprivation therapy (ADT) is a fundamental component of treatment for metastatic hormone-sensitive prostate cancer (mHSPC), but it accelerates bone mineral density loss and increases fracture risk. ...
  • Obesity and Metabolic Syndrome in Childhood Leukemia and in Long-Term Survivors: Causes and Personalized Treatments 
    Corominas-Herrero, Francisco-José; Navas-Carrillo, Diana; Ortega-García, Juan-Antonio; Martínez-Romera, Isabel; Orenes-Piñero, Esteban (MDPI, 2025-10-27)
    Acute lymphoblastic leukemia (ALL) remains the most frequent pediatric malignancy, accounting for approximately 34% of all pediatric cancers, with remarkable improvements in survival (approximately 85%) due to advances in ...
  • Predictors of Distant Metastasis in Patients with Medullary Thyroid Carcinoma 
    Ros-Madrid, Inmaculada; Febrero, Beatriz; Cano-Mármol, Rosario-Paloma; Ferrer-Gómez, Mercedes; Rodríguez-González, José-Manuel (MDPI, 2025-09-30)
    Background/Objectives: The presence of distant metastases is the main cause of death in medullary thyroid carcinoma (MTC). However, due to the rarity of this cancer, few studies have thoroughly analyzed the variables ...
  • Effect of Acellular Dermal Matrix in Postoperative Outcomes in Tissue Expander Breast Reconstruction After Immediate Mastectomy 
    Nova-Tayant, Óscar; Saorín-Gascón, Eduardo; Moreno-Villalba, Ramón-Andrés; Mora-Ortiz, María-Asunción; Fernandez-Pascual, Clemente-José; Vera-García, Pablo-José; Piñero-Madrona, Antonio (MDPI, 2025-09-30)
    Background: Breast reconstruction following mastectomy has become an essential procedure in breast cancer treatment due to its positive impact on patients' quality of life. Among the various reconstruction techniques, the ...
  • The Impact of Minimally Invasive Surgery in the Treatment of Ovarian Cancer in Young Patients 
    Heras, Marta; Gorostidi, Mikel; Arencibia, Octavio; Minig, Lucas; Marti, Lola; Gracia, Myriam; Lekuona, Arantxa; Ñíguez-Sevilla, Isabel; Gil-Ibáñez, Blanca; Díaz-Feijoo, Berta; Gómez, Ana; Lara, Ana; Álvarez, Rosa; Corraliza, Virginia; Vilches, José-Carlos; de-Marino, María; Coronado, Pluvio; Duch, Silvia; Bayon, Emilio; Aparicio, Iria; del-Moral, Raquel; Mancebo, Gemma; Lete, Inaki; Tetilla, Violeta; Zapardiel, Ignacio (MDPI, 2025-06-23)
    Ovarian cancer is more frequently diagnosed in post-menopausal patients, and it is considered an aggressive tumor that is usually diagnosed at an advanced stage [...].
  • Combined Hyperthermic Intraperitoneal Chemotherapy and Normothermic Intraperitoneal Chemotherapy Long-Term After Interval Cytoreduction in Ovarian Cancer: A Phase I Clinical Trial (BICOV1) 
    González-Gil, Alida; Gil-Gómez, Elena; Olivares-Ripoll, Vicente; Cerezuela-Fernández-de-Palencia, Álvaro; Martínez-García, Jerónimo; Sánchez-Martínez, Domingo-Antonio; Guijarro-Campillo, Alberto-Rafael; Cascales-Campos, Pedro-Antonio (MDPI, 2025-06-12)
    Backgroud: Ovarian cancer is the deadliest gynecologic malignancy, with most patients presenting with peritoneal dissemination at diagnosis. Complete cytoreduction and sensitivity to platinum-based systemic chemotherapy ...
  • Diagnostic Delay in Soft Tissue Sarcomas: A Review 
    Fernández, Juan-Ángel; Gómez, Beatriz; Díaz-Gómez, Daniel; López, Irene; Lozano, Pablo; Muñoz, Paula; Muñoz-Casares, Francisco-Cristóbal; Olivares-Ripoll, Vicente; Vasques, Hugo; Asencio-Pascual, José-Manuel (MDPI, 2025-05-31)
    BACKGROUND/OBJECTIVES: To review the problem of diagnostic delay in soft tissue sarcomas with the aim of identifying its causes and consequences, understanding how to clinically suspect and refer them, and evaluating the ...
  • Challenges of Nontherapeutic Laparotomy in Patients with Peritoneal Surface Malignancies Selected for Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy 
    Gil-Gómez, Elena; González-Gil, Alida; Olivares-Ripoll, Vicente; Cerezuela-Fernández-de-Palencia, Álvaro; López-Hernández, Francisco; Martínez-Espí, Álvaro; Martínez-García, Jerónimo; Barcelo, Francisco; Guijarro-Campillo, Alberto-Rafael; Cascales-Campos, Pedro-Antonio (MDPI, 2025-04-25)
    BACKGROUND: This study aimed to analyze the morbidity, mortality, and survival outcomes in patients with peritoneal surface malignancies who were initially considered candidates for cytoreductive surgery (CRS) with ...
  • Optimizing Outcomes in Breast Reconstruction: The Role of Hormonal Therapy Management 
    Saorín-Gascón, Eduardo; Nova-Tayant, Óscar; Moreno-Villalba, Ramón-Andrés; García-Contreras, Juan-de-Dios; Fernandez-Pascual, Clemente-José; Mora-Ortiz, Asunción-M; Servet-Pérez-de-Lema, Carmen-María; Quiles-Hevia, Alba; Piñero-Madrona, Antonio (MDPI, 2025-02-17)
    BACKGROUND: Breast cancer comprises diverse subtypes with prognostic and therapeutic implications. Hormone therapy plays a crucial role in managing tumors expressing hormonal receptors, but its impact on breast reconstruction ...
  • Could microRNA Analysis Help in the Management of Medullary Thyroid Cancer? 
    Febrero, Beatriz; Ros-Madrid, Inmaculada; Revilla-Nuin, Beatriz; Abellan, Miriam; Ruiz-Manzanera, Juan-José; Gómez, Joaquín; Rodríguez-González, José-Manuel (MDPI, 2025-02-13)
    Introduction. In medullary thyroid carcinoma (MTC), calcitonin levels and TNM staging are established prognostic factors. However, the diagnostic accuracy of cytology in MTC is poor. In this context, microRNAs (miRNAs) may ...
  • Dose-Escalated SBRT for Borderline and Locally Advanced Pancreatic Cancer: Resectability Rate and Pathological Results of a Multicenter Prospective Study 
    Salas-Salas, Bárbara; Ferrera-Alayon, Laura; Espinosa-López, Alberto; Pérez-Rodríguez, María-Luisa; Alayon-Afonso, Antonio-Alayon; Vera-Rosas, Andrés; García-Plaza, Gabriel; Chicas-Sett, Rodolfo; Martínez-Martin, María-Soledad; Salcedo, Elisa; Kannemann, Andrea; Lloret-Sáez-Bravo, Marta; Lara, Pedro-C (MDPI, 2025-01-09)
    OBJECTIVE: We demonstrated for the first time the safety and feasibility of escalating up to 55 Gy/11 Gy/fr/5fr in borderline (BRPC)/unresectable locally advanced pancreatic cancer (LAPC), using the standard LINAC platform. ...
  • Exposure to Sulfur Hexafluoride Influences Viability in Cell Transplant Suspensions 
    Martínez-Alarcón, Laura; Liarte, Sergio; Abellaneda-Bernal, Juana-María; Quereda, Juan-J; Mendonca, Livia; Muñoz, Antonio; Ramírez, Pablo; Ramis-Vidal, Guillermo (MDPI, 2025-10-31)
    Cell transplantation is often performed with ultrasonographic guidance for accurate delivery through injection. In such procedures, using ultrasonographic contrast greatly improves target delivery. However, accumulating ...
  • Spinal Cord Stimulation in Painful Diabetic Neuropathy: Advances, Outcomes, and Future Directions 
    Gazzeri, Roberto; Mosca, Jacopo; Occhigrossi, Felice; Galarza, Marcelo; Schiaffini, Riccardo; Varrassi, Giustino; Mercieri, Marco; Leóni, Matteo-Luigi-Giuseppe (MDPI, 2025-12-12)
    Painful diabetic neuropathy (PDN) is a common complication of diabetes mellitus, often inadequately managed by conventional pharmacological therapies. Alternative interventions, including spinal cord stimulation (SCS), ...
  • The Long-Term Outcomes of Corticosteroid Use in COVID-19 Patients with Cardiovascular Disease: A Propensity-Matched Analysis from the Multi-Center International Prospective Registry (HOPE-2) 
    García-Onrubia, Jorge; Vazirani, Ravi; Feltes, Gisela; Sánchez-del-Hoyo, Rafael; Viana-Llamas, María-Carmen; Raposeiras-Roubin, Sergio; Romero, Rodolfo; Alfonso-Rodríguez, Emilio; Uribarri, Aitor; Santoro, Francesco; Becerra-Muñoz, Victor; Pepe, Martino; Castro-Mejia, Alex-F; Signes-Costa, Jaime; González, Adelina; Marín, Francisco; López-Pais, Javier; Cerrato, Enrico; Vázquez-Cancela, Olalla; Espejo-Paeres, Carolina; López-Masjuan, Álvaro; Velicki, Lazar; El-Battrawy, Ibrahim; Ramakrishna, Harish; Fernández-Ortiz, Antonio; Núñez-Gil, Ivan-J (MDPI, 2025-10-30)
    Introduction: Corticosteroid therapy has been demonstrated to improve prognosis and reduce mortality in patients with severe Coronavirus Disease 2019 (COVID-19) infection by attenuating the exaggerated inflammatory response ...
  • Ethylbenzene Exposure and Bronchoalveolar CD4/CD8 T Cells in Hypersensitivity Pneumonitis Development and Clinical Outcome 
    Minguela-Puras, Alfredo; Campillo, José-Antonio; Aguilar-Sanchis, María-Isabel; Baeza-Caracena, Antonia; Esquembre, Francisco; Novoa-Bolívar, Erika-M; González-López, Rosana; Otalora, Almudena; Ortuño-Hernández, Cristina; López-Hernández, Ruth; Gimeno-Arias, Lourdes; Ruiz-Lorente, Inmaculada; Ceballos, Diana; Solana-Martínez, Elena; Alcantara-Fructuoso, Juan; Muro-Amador, Manuel; Ros, José-A (MDPI, 2025-10-24)
    Background: Hypersensitivity pneumonitis (HP) is an interstitial lung disease (ILD) characterized by inflammation of the lung parenchyma, alveoli and bronchioles induced by inhalation of organic compounds. Bird-related-HP ...
  • Donor-Derived Cell-Free DNA in Allograft Transplantation: Exaggerated Hope or Cautious Reality? 
    Fernández-González, Marina; Llorente-Vinas, Santiago; Botella-Martínez, Carmen; Galián, José-Antonio; González-López, Rosana; Alegría-Marcos, María-José; Hita-Ruiz, Alicia; Moya-Quiles, María-Rosa; Martínez-Banaclocha, Helios; Muro-Pérez, Manuel; Muro, Javier; Minguela-Puras, Alfredo; Legaz, Isabel; Muro-Amador, Manuel (MDPI, 2025-09-23)
    Nowadays, there have truly been spectacular advances in surgical techniques, the preservation of organs for transplants, the optimal and efficient selection of both donors and recipients, a more efficient diagnosis and ...
  • Pharmacogenomic Study of SARS-CoV-2 Treatments: Identifying Polymorphisms Associated with Treatment Response in COVID-19 Patients 
    Serra-Llovich, Alexandre; Cullell, Natalia; Maronas, Olalla; Jose-Herrero, María; Cruz, Raquel; Almoguera, Berta; Ayuso, Carmen; López-Rodríguez, Rosario; Domínguez-Garrido, Elena; Ortiz-López, Rocío; Barreda-Sánchez, María; Corton, Marta; Dalmau, David; Calbo, Esther; Boix-Palop, Lucía; Dietl, Beatriz; Sangil, Anna; Gil-Rodríguez, Almudena; Guillén-Navarro, Encarna; Mancebo, Esther; Lira-Albarran, Saul; Mínguez, Pablo; Paz-Artal, Estela; Olivera, Gladys-G; Recarey-Rama, Sheila; Sendra, Luis; Zucchet, Enrique-G; López-de-Heredia, Miguel; Flores, Carlos; Riancho, José-A; Rojas-Martínez, Augusto; Lapunzina, Pablo; Carracedo, Ángel; Arranz, María-J (MDPI, 2025-02-21)
    Background/Objectives: The COVID-19 pandemic resulted in 675 million cases and 6.9 million deaths by 2022. Despite substantial declines in case fatalities following widespread vaccination campaigns, the threat of future ...
  • Differential Role of NKG2A/HLA-E Interaction in the Outcomes of Bladder Cancer Patients Treated with M. bovis BCG or Other Therapies 
    Ruiz-Lorente, Inmaculada; Gimeno-Arias, Lourdes; López-Abad, Alicia; López-Cubillana, Pedro; Fernández-Aparicio, Tomás; Asensio-Egea, Lucas-Jesús; Moreno-Avilés, Juan; Doñate-Íñiguez, Gloria; Guzmán-Martínez-Valls, Pablo-Luis; Server, Gerardo; Ferri-Ñíguez, Belén; Campillo, José-Antonio; Martínez-Sánchez, María-Victoria; Minguela-Puras, Alfredo (MDPI, 2025-01-10)
    Background: Immunotherapy is gaining great relevance in both non-muscle-invasive bladder cancer (NMIBC), with the use of bacille Calmette-Guerin (BCG), and in muscle-invasive BC (MIBC) with anti-checkpoint therapies blocking ...
  • Defibrotide for Protecting Against and Managing Endothelial Injury in Hematologic Malignancies and COVID-19 
    Richardson, Edward; Mo, Clifton-C; Calabretta, ELeónora; Corrado, Francesco; Kocoglu, Mehmet-H; Baron, Rebecca-M; Connors, Jean-Marie; Iacobelli, Massimo; Wei, Lee-Jen; Benjamin, Emily-J; Rapoport, Aaron-P; Díaz-Ricart, Maribel; Martínez-Mellado, Antonio-José; Carlo-Stella, Carmelo; Richardson, Paul-G; Moraleda-Jiménez, José-María (MDPI, 2025-07-14)
    Defibrotide, which is approved for treating hepatic veno-occlusive disease (VOD)/sinusoidal obstruction syndrome (SOS), exhibits pleiotropic anti-inflammatory, anti-thrombotic, and fibrinolytic properties, conferring broad ...
  • Diagnostic Utility of Bronchoalveolar Lavage Flow Cytometric Leukocyte Profiling in Interstitial Lung Disease and Infection 
    Novoa-Bolívar, Erika-M; Ros, José-A; Pérez-Fernández, Sonia; Campillo, José-Antonio; López-Hernández, Ruth; González-López, Rosana; Ruiz-Lorente, Inmaculada; Otalora-Alcaraz, Almudena; Ortuño-Hernández, Cristina; Gimeno-Arias, Lourdes; Ceballos-Francisco, Diana; Muro-Amador, Manuel; Solana-Martínez, Elena; Martínez-Camblor, Pablo; Minguela-Puras, Alfredo (MDPI, 2025-04-17)
    Interstitial lung diseases (ILD) represent a diverse group of disorders that primarily affect the pulmonary interstitium and, less commonly, involve the alveolar and vascular epithelium. Overlapping clinical, radiological ...

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