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Envíos recientes

02.01.01. Investigación y comunicación científica: Envíos recientes

  • A prediction tool for malnutrition and sarcopenia in patients with gastroenteropancreatic neuroendocrine neoplasms: results from NUTRIGETNE (GETNE-S2109) study 
    Argente-Pla, María; Sampedro-Núñez, Miguel-Antonio; García-Carbonero, Rocío; Custodio, Ana; Hernando, Jorge; Suárez, Lorena; Hernández-Rienda, Lorena; Peiro, Inmaculada; Alonso, Vicente; Serrano, Raquel; Valdes, Nuria; Melian, Marcos; Febrero, Beatriz; Biarnes, Josefina; Díaz-Pérez, José-Angel; Molina-Cerrillo, Javier; López, Carlos; Martínez-Olmos, Miguel-Ángel; Merino-Torres, Juan-Francisco; Capdevila, Jaume; del-Olmo-García, Maribel (FRONTIERS MEDIA SA, 2026-05-26)
    INTRODUCTION: Malnutrition and sarcopenia are prevalent among patients with gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs), necessitating simple assessment tools to identify potentially malnourished patients. ...
  • Long-Term Colorectal Cancer Incidence After Adenoma and Serrated Polyp Removal: Results From the Colonprev Trial 
    Cubiella, Joaquín; García-Benito, Carme; Castells, Antoni; Quintero, Enrique; Bujanda, Luis; Castan-Cameo, Susana; Díaz-Tasende, José; Lanas, Ángel; Ono-Ono, Akiko; Frias-Arrocha, Eladio; Hernández, Cristina; Jover, Rodrigo; Andreu, Montserrat; Carballo-Álvarez, Luis-Fernando; Morillas, Juan-Diego; Salas, Dolores; Regueiro-Exposito, Cristina; Dávila-Pinon, Pedro; Díez-Martin, Astrid (WILEY, 2026-06)
    BACKGROUND: The risk of colorectal cancer (CRC) after serrated polyp resection remains unclear, and current surveillance recommendations rely on limited evidence. We evaluated CRC incidence in individuals with advanced ...
  • Interaction of Intraprocedural Antiplatelets and Intravenous Thrombolysis in Acute Intracranial Stenting: RESISTANT Registry Subanalysis 
    Rodríguez-Calienes, Aaron; Cruz-Criollo, Leonardo; Kontowicz, Eric; Olive-Gadea, Marta; Diana, Francesco; Kaesmacher, Johannes; Mujanovic, Adnan; Geyik, Serdar; Senadim, Songul; Cervo, Amedeo; Salcuni, Andrea; Piano, Mariangela; Moreu, Manuel; López-Frias, Alfonso; Hassan, Ameer-E; Miller, Samantha; Zapata-Arriaza, Elena; de-Alboniga-Chindurza, Asier; Bergui, Mauro; Molinaro, Stefano; Sousa, Joao-Andre; Gomes, Fabio; Sargento-Freitas, Joao; Alexandre, Andrea; Pedicelli, Alessandro; Hofmeister, Jeremy; Machi, Paolo; Scarcia, Luca; Kalsoum, Erwah; Amorim, José; Meira, Torcato; Renieri, Leonardo; Capasso, Francesco; Romano, Daniele; Barcena-Ruiz, Eduardo; Seoane, David; Abdalkader, Mohamad; Klein, Piers; Nguyen, Thanh-N; da-Camara, Catarina-Perry; Brito, Anderson; Abdelhakim, Nashwa; Fragata, Isabel; Yavagal, Dileep-R; Charles, Jude-H; Rodríguez-Castro, José; Vega, Pedro; Ozdemir, Atilla-Ozcan; Kocabas, Zehra-Uysal; Smajda, Stanislas; Al-Salman, Sadiq; Khalife, Jane; Jovin, Tudor-G; Biraschi, Francesco; Richetti, Francesca; Castro, Pedro; Albuquerque, Luis; Siddiqui, Adnan; Jaikumar, Vinay; Navia, Pedro; Ntoulias, Nikolaos; Psychogios, Marios; Velo, Mariano; Zamarro-Parra, Joaquín; de-Paco, Gonzalo; Ashouri, Yazan; AlMajali, Mohammad; Arenillas, Juan-F; Sierra, Alicia; Romoli, Michele; Marto, Joao-Pedro; Yaghi, Shadi; Ribo, Marc; Tomasello, Alejandro; Requena, Manuel; Ortega-Gutiérrez, Santiago (WILEY, 2026-06-09)
    INTRODUCTION/OBJECTIVE: Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of ...
  • Evaluating total tumor load (TTL) to predict metastasis in four or more axillary lymph nodes in HR +/HER2-breast cancer patients: the TULIP4N+study 
    Zamora, Esther; Piñero-Madrona, Antonio; Sperduti, Isabella; Sapino, Anna; Fougo, José-Luis; Peg, Vicente (SPRINGER INT PUBL AG, 2026-06-06)
    PURPOSE: To validate the predictive value of Total Tumor Load (TTL), based on Cytokeratin 19 (CK19) mRNA copy number measured by OSNA in sentinel lymph nodes (SLNs), and to establish an optimal cut-off for identifying HR ...
  • Worldwide Impact of Human Development and Inequality on the Prevalence of Asthma, Rhinoconjunctivitis and Eczema. Global Asthma Network's Ecological Study 
    García-Marcos, Luis; Chiang, Chen-Yuan; Asher, M-Innes; Marks, Guy-B; El-Sony, Asma; Masekela, Refiloe; Bissell, Karen; Ellwood, Eamon; Ellwood, Philippa; Pearce, Neil; Strachan, David-P; Martínez-Torres, A-Elena; Sánchez-Solís, Manuel; Mortimer, Kevin; Morales, Eva (WILEY, 2026-06-04)
    BACKGROUND: Lower-income countries have lower asthma prevalence. However, how differences in human development and inequality can explain changes in the prevalence of asthma and allergic diseases is not known. METHODS: The ...
  • Fingolimod increases cellular resistance to HIV-1 infection and limits viral reservoir size in peripheral CD4+ T-cells 
    Moraga, Elisa; Climent, Nuria; Sánchez-Molina, Alejandro; Vicens-Artes, Sonia; Maleno, María-José; Valero-López, Gabriel; Galera-Peñaranda, Carlos; Ambrosioni, Juan; Miro, José-M; Mallolas, Josep; Albendin-Iglesias, Helena; Alcami, José; Sánchez-Palomino, Sonsoles (PUBLIC LIBRARY SCIENCE, 2026-06-03)
    BACKGROUND: Fingolimod, a treatment for multiple sclerosis (MS), decreases autoreactive lymphocytes by lymph node sequestration. In vitro, fingolimod decreases HIV-1 infection and viral reservoir (VR) through SAMHD1 ...
  • Developmental outcome of electroencephalographic findings in SYNGAP1 encephalopathy (vol 12, 1321282, 2024) 
    Ribeiro-Constante, Juliana; Tristan-Noguero, Alba; Martínez-Calvo, Fernando-Francisco; Ibáñez-Mico, Salvador; Pena-Segura, José-Luis; Ramos-Fernández, José-Miguel; Moyano-Chicano, María-del-Carmen; Camino-Leon, Rafael; Soto-Insuga, Víctor; González-Alguacil, Elena; Valera-Dávila, Carlos-Valera; Fernández-Jaén, Alberto; Plans, Laura; Camacho, Ana; Visa-Rene, Nuria; Martin-Tamayo-Blazquez, María-del-Pilar; Paredes-Carmona, Fernando; Martí-Carrera, Itxaso; Hernández-Fabián, Aranzazu; Tomás-Davi, Meritxell; Casadesús-Sánchez, Merce; Cuesta-Herraiz, Laura; Fuentes-Pita, Patricia; Bermejo-González, Teresa; O'Callaghan, Mar; Iglesias-Santa-Polonia, Federico-Felipe; Cazorla, María-Rosario; Ferrando-Lucas, María-Teresa; González-Meneses, Antonio; Sala-Coromina, Julia; Macaya, Alfons; Lasa-Aranzasti, Amaia; Cueto-González, Anna-Ma; Valera-Parraga, Francisca; Campistol-Plana, Jaume; Serrano, Mercedes; Alonso, Xenia; del-Castillo-Berges, Diego; Schwartz-Palleja, Marc; Illescas, Sofía; Ramírez-Camacho, Alia; Sans-Capdevila, Óscar; García-Cazorla, Ángeles; Bayes, Alex; Alonso-Colmenero, Itziar (FRONTIERS MEDIA SA, 2026-05-18)
    [This corrects the article DOI: 10.3389/fcell.2024.1321282.].
  • Beta-Thalassemia in Spain: Results From the National Thalassemia Registry and Molecular Analysis of Patients With Transfusion-Dependent Thalassemia 
    Villegas, Ana; Ropero, Paloma; González, Fernando-Ataulfo; Morado, Marta; Menor, María; de-la-Iglesia, Silvia; López-Rubio, Montserrat; Salido-Fiérrez, Eduardo-José; Abio, Mariola; Senent, María-Leonor; Recasens, Valle; Vagace, José-Manuel; Fonte, Cristina; Hernández-Rivas, Jesus-María; Raya, José-María; Rios, Pablo; Peri, Valeria-Luciana; Herrera, Keneth-A; Tenorio, María-Concepción; Lo-Riso, Laura; Tena, Juan; Molina, María-Angustias; Vara, Miriam; Rodríguez, Isabel; Ricard, Pilar; Gómez, Miguel; Dusacovschi, Oana-Popa; Vidan, Julia-María; Groiss, Jorge; Ferre, Oscar; Orbe, Irene; López, Rosa-María; Ugalde, Nazaret; Hidalgo, Manuela-Ines; Hinojosa, Cristina; Rodríguez, Ana-Isabel; Herrera, Esther; Muruzabal, María-Josefa; del-Carmen-Hernández, María; Marco, Josefa-Esperanza; Benavente, Celina (WILEY, 2026-06-02)
    BACKGROUND: Beta-thalassemia is a genetically heterogeneous hemoglobinopathy with marked clinical variability. In Spain, comprehensive nationwide data on transfusion-dependent beta-thalassemia (TDT) remain limited, ...
  • A targeted combination therapy achieves effective pancreatic cancer regression and prevents tumor resistance 
    Liaki, Vasiliki; Barrambana, Sara; Kostopoulou, Myrto; Lechuga, Carmen-G; Zamorano-Domínguez, Elena; Acosta-Gallego, Domingo; Morales-Cacho, Lucía; Álvarez, Ruth; Sun, Pian; Rosas-Pérez, Blanca; Barrero, Rebeca; Jiménez-Parrado, Silvia; López-García, Alejandra; San-Roman, Marta; López-Gil, Juan-Carlos; Drosten, Matthias; Sainz, Bruno; Musteanu, Mónica; Caleiras, Eduardo; Dusetti, Nelson; Poli, Valeria; Sánchez-Bueno, Francisco; Guerra, Carmen; Barbacid, Mariano (NATL ACAD SCIENCES, 2026-06-09)
    Pancreatic ductal adenocarcinoma (PDAC) has one of the lowest cancer survival rates. Recent studies using RAS inhibitors have opened the door to more efficacious therapies although their beneficial effect is still limited ...
  • Textbook outcome in surgery for primary hyperparathyroidism: first steps toward a composite quality metric 
    Ruiz-Manzanera, Juan-José; Febrero, Beatriz; Escavy, Natalia; Abellán, Miriam; Soriano, María-Teresa; Aliaga, Alfonso; Ros-Madrid, Inmaculada; Rodríguez-González, José-Manuel (SPRINGER-VERLAG ITALIA SRL, 2026-05-28)
    Textbook Outcome (TO) is a composite quality metric reflecting the ideal postoperative course through the simultaneous achievement of multiple desirable endpoints. Although widely explored in other surgical specialties, ...
  • Coexistence of neck pain and low back pain, and their association with demographic, occupational, and spine MRI-based morphological factors in dentists 
    López-Morales, Ana; Baño-Alcaraz, Aitor; López-Nicolas, Manuel; García-Vidal, José-Antonio; Cánovas-Ambit, Germán (SPRINGER, 2026-05-27)
    BACKGROUND: The prevalence of musculoskeletal pain, particularly low back pain (LBP) and neck pain (NP), is notably high among dentists. Several studies have examined associated factors such as age, gender, long working ...
  • Restoring Physiological Normoxia as an Adjuvant Strategy to Improve Cancer Treatment Outcomes 
    Mas-Bermejo, Carlos; Mas-Gómez, Carlos; Sevilla-García, María-Agustina; O'Connor-Reina, Carlos; Falardo-Ramos, Susana; Alonso-Romero, José-Luis; Bravo-González, Luis-Alberto (DOVE MEDICAL PRESS LTD, 2026-05)
    Hypoxia is a central driver of cancer progression, immune evasion, and resistance to anticancer therapies. While hypoxia has traditionally been considered an intrinsic feature of the tumor microenvironment, growing evidence ...
  • Immunoscore and beyond: evolution and clinical integration of immune contexture-based biomarkers across solid tumours 
    Orenes-Piñero, Esteban; Ros-Martínez, Silverio; Alonso-Romero, José-Luis; Ortega-García, Juan-Antonio (FRONTIERS MEDIA SA, 2026-05-08)
    The tumour immune microenvironment is increasingly recognised as a critical determinant of cancer progression, prognosis, and therapeutic response, challenging the sufficiency of anatomy-based staging systems such as TNM. ...
  • Implementation of third-generation digital PCR for non-invasive prenatal diagnosis of sickle cell disease and early detection. Pilot study 
    Ferrer-Benito, Sara; Gómez-Álvarez, MigueL; Torrejón-Martínez, María-Josefa; López-Rubio, Montserrat; del-Orbe-Barreto, Rafael-Andrés; Arbeteta-Juanis, Jaime; Muruzabal-Siges, María-Josefa; Salido-Fiérrez, Eduardo-José; Mateo, Aranzazu-García; Recasens, Valle; Martínez-Nieto, Jorge; Villegas-Martínez, Ana; González, Fernando-Ataulfo; Ortega-Montero, Ana-Belén; García-Moreno, Laura; Ropero-Gradilla, Paloma; Benavente-Cuesta, Celina (FRONTIERS MEDIA SA, 2026-05-08)
    Sickle cell disease (SCD) is one of the most prevalent autosomal recessive conditions worldwide, affecting more than 600,000 newborns annually. Despite advances in treatment, it remains a chronic condition requiring lifelong ...
  • Third Allogeneic Stem Cell Transplantation in Children: A Multicenter Analysis From the Spanish GETH-TC Pediatric Group 
    Sisinni, Luisa; Vinagre-Enriquez, Sara; Villalón-Herrera, Marta; Plaza-Fornieles, Mercedes; López-Torija, Ivan; Urtasun-Erburu, Andrea; Alonso-García, Laura; García, Alexandra-Regueiro; Trabazo-del-Castillo, María; Bardon-Cancho, Eduardo-J; Leon-Triana, Odelaisy; Miñarro-Chacón, Carla; Fuster-Soler, José-Luis; Pérez-Martínez, Antonio; Balsalobre-López, Pascual; González-Vicent, Marta; Díaz-de-Heredia, Cristina (WILEY, 2026-05-12)
    Third allogeneic hematopoietic stem cell transplantation (HSCT3) is rarely performed in pediatric patients and is associated with high toxicity and mortality. Data on outcomes in this setting remain scarce. We conducted a ...
  • Phase IIB, Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Intravenous Defibrotide for the Prevention and Treatment of Respiratory Distress and Cytokine Release Syndrome in COVID-19 
    Jara-Rubio, Rubén; Martínez-Mellado, Antonio-José; Kiwitt-Cardenas, Jonathan; Clavel, José-G; García-Pérez, Bartolomé; Castro, Pedro; Díaz-Ricart, Maribel; Carrillo-Alcaraz, Andrés; López-Bernus, Amparo; Bernal-Morell, Enrique; Roura, Aychel; Marín, Sonia; Ruiz-López, Francisco-José; Solana-Martínez, Elena; Martínez-Baño, Domingo; Albacete-Moreno, Carlos-L; Andreu-Soler, Enriqueta; Tellez-Santoyo, Adrián; Fernández-Méndez, Sara; Noguera-Velasco, José-Antonio; Cebreiros-López, Iria; Parrilla, Andrés; Espuny-Miró, Alberto; García-Bernal, David; Blanquer-Blanquer, Miguel; Sánchez-Salinas, Andrés; Iniesta-Martínez, Francisca; Hernández-García, Cristina; Muro-Amador, Manuel; Minguela-Puras, Alfredo; Moreno-Docón, Antonio; Torres-Cantero, Alberto-M; Muñoz-García, María; Serrano, Manuel; Iacobelli, Massimo; Carlo-Stella, Carmelo; Wei, Lee-Jen; Richardson, Paul-G; Moraleda-Jiménez, José-María (WILEY, 2026-05-12)
    INTRODUCTION: Endothelial dysfunction is key in COVID-19 pathogenesis. This randomized, double-blind phase IIb trial investigated continuous intravenous infusion of defibrotide in patients hospitalized with SARS-CoV-2 ...
  • Old donors for young heart transplant recipients: Clinical implications of an emerging phenomenon. 
    Vilches-Miguel, Lidia; Almenar-Bonet, Luis; Crespo-Leiro, María-G; Hernández-Pérez, Francisco-J; González-Vilchez, Francisco; García-Cosio-Carmena, María-Dolores; Sobrino-Marquez, José-M; Farrero-Torres, Marta; González-Costello, José; Martínez-Selles, Manuel; Arizon-del-Prado, José-M; Mirabet-Pérez, Sonia; Díaz-Molina, Beatriz; de-la-Fuente-Galan, Luis; Blasco-Peiro, Teresa; Garrido-Bravo, Iris-Paula; Rabago-Juan-Aracil, Gregorio; García-Quintana, Antonio; Alfonso-Manterola, Fernando; Segovia-Cubero, Javier (ELSEVIER, 2026-05)
    BACKGROUND: Historically, heart transplantation (HTx) has focused on matching recipients with organs from donors of similar or younger age. However, due to the growing shortage of donors, especially in Europe, organs from ...
  • Endovascular treatment for medium or distal vessel occlusion stroke (DISTAL): 12-month outcomes of a multicentre, open-label, randomised trial 
    Fischer, Urs; Brehm, Alex; Ribo, Marc; Rizzo, Federica; Strbian, Daniel; Raty, Silja; Arenillas, Juan-F; Martínez-Galdamez, Mario; Hajdu, Steven-D; Michel, Patrik; Gralla, Jan; Piechowiak, Eike; Kaiser, Daniel-P-O; Puetz, Volker; van-den-Bergh, Frans; de-Raedt, Sylvie; Bellante, Flavio; Dusart, Anne; Hellstern, Victoria; Khanafer, Ali; Parrilla, Guillermo; Morales, Ana; Kirschke, Jan-S; Wunderlich, Silke; Fiehler, Jens; Thomalla, Gotz; Lemmens, Robin; Peluso, Jo-P; Bolognese, Manuel; von-Hessling, Alexander; van-Es, Adriaan; Kruyt, Nyika-D; Coutinho, Jonathan-M; Castaño, Carlos; Minnerup, Jens; van-Zwam, Wim; D'Hondt, Elisabeth; Nolte, Christian-H; Machi, Paolo; Loehr, Christian; Mattle, Heinrich-P; Buhk, Jan-Hendrik; Kaesmacher, Johannes; Dobrocky, Tomas; Papanagiotou, Panagiotis; Alonso, Angelika; Holtmannspoetter, Markus; Zini, Andrea; Renieri, Leonardo; Keil, Fee; van-den-Wijngaard, Ido; Kagi, Georg; Terceno, Mikel; Wiesmann, Martin; Amaro, Sergio; Fragata, Isabel; Katan, Mira; Leker, Ronen-R; Saver, Jeffrey-L; Staals, Julie; Rommers, Nikki; Balmer, Luzia; Psychogios, Marios (ELSEVIER SCIENCE INC, 2026-06)
    BACKGROUND: Long-term evidence for endovascular treatment in medium or distal vessel occlusion stroke is scarce. Three out of four randomised trials reported no benefit of endovascular treatment over best medical treatment ...
  • Postmortem genetic testing in sudden death: clinical and medico-legal implications 
    Sabater-Molina, María; Nicolás-Rocamora, Elisa; Munteanu, Serena; Fuentes-Bermejo, María-Dolores; Osuna-Carrillo-Albornoz, Eduardo; Pérez-Cárceles, María-Dolores; Pastor-Quirante, Francisco; Gimeno-Blanes, Juan-Ramón; Hernández-del-Rincón, Juan-Pedro (SPRINGER, 2026-05-08)
    BACKGROUND: Anatomopathological autopsy and postmortem genetic testing play a crucial role in forensic medicine, particularly in elucidating the causes of sudden death (SD) that remain unexplained by conventional methods. ...
  • Prevalence and risk factors of asthma, rhinoconjunctivitis and eczema in the very extreme environment of Naryn, Kyrgyzstan 
    Sulaimanov, Shaiirbek-A; Martínez-Torres, A-Elena; García-Marcos, Luis; Asheraliev, Mukhtar-E; Moidunov, Artur-A; Brimkulov, Nurlan-N; Muratova, Zhanara-K; Omusheva, Saltanat-E; Tynybekov, Kubanych-T; Narkoziev, Baktybek-E (ELSEVIER, 2026-05)
    BACKGROUND: There is not much information about the prevalence of allergic diseases in high altitudes in central Asia; and even less on their potential risk of protective factors. METHODS: A survey using the Global Asthma ...

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