Repositorio Dspace

Envíos recientes

03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla): Envíos recientes

  • In Vitro Evaluation of Novel Resin-Modified Calcium Silicate Cements for Minimally Invasive Vital Pulp 
    Rodríguez-Lozano, Francisco-Javier; Pérez-Guzmán, Nuria; García-Ríos, Paula; García-Bernal, David; Mora, Alejandro; López-García, Sergio (ELSEVIER, 2026-02)
    OBJECTIVES: This study aimed to evaluate the biological effects of one conventional calcium silicate-based cement (MTA Angelus) and three resin-modified formulations (TheraCal PT, TheraBase Ca, and TheraCal LC) on human ...
  • Complex IV deficiency due to COX4I1 deep intronic and de novo variants results in progressive motor impairment and Leigh syndrome 
    Ugarteburu, Olatz; Farre-Tarrats, Laia; Muñoz-Pujol, Gerard; Unceta, María; De-Las-Heras, Javier; García-Ribes, Ainhoa; Arza-Ruesga, Arantza; de-la-Morena-Barrio, Belén; Arauz-Garofalo, Gianluca; Gay, Marina; Garrabou, Gloria; Corral, Javier; Vilaseca, Marta; Ribes, Antonia; García-Villoria, Judit; Gort, Laura; Tort, Frederic (ELSEVIER SCI LTD, 2026-01)
    COX4I1 gene encodes cytochrome c oxidase subunit 4 isoform 1, involved in the early assembly stages of mitochondrial respiratory chain complex IV. To date, COX4I1 pathogenic variants have been reported in only a few cases, ...
  • Cardiovascular and renal outcomes according to KDIGO stages of chronic kidney disease in the Spanish population: Insights from real-world evidence 
    Santamaria, Rafael; Escobar, Carlos; Aranda, Unai; Palacios, Beatriz; Capel, Margarita; Hernández, Ignacio; Cebrián-Cuenca, Ana-María; Alcazar, Roberto; Gorostidi, Manuel (SOCIEDAD ESPAÑOLA DE NEFROLOGIA DR RAFAEL MATESANZ, 2025-10)
    OBJECTIVE: Real-world analysis of the clinical profile, treatments, major adverse cardiovascular and renal events (MACE and MARE) in patients with different stages of chronic kidney disease (CKD) as defined by KDIGO ...
  • The role of baseline and persistent depression in adjuvant cancer therapy: impact on toxicity and quality of life 
    Obispo, Berta; Calderon, Caterina; Carmona-Bayonas, Alberto; Ghanem, Ismael; Cano-Cano, Juana Maria; Jimenez-Fonseca, Paula (ELSEVIER SCIENCE INC, 2025-10)
    INTRODUCTION: Depression is common among cancer patients, adversely affecting treatment adherence, toxicity, and quality of life (QoL). However, its course during adjuvant therapy and its impact on outcomes in resected ...
  • Optimization of ALPPS stage II timing with the APRI/ALBI score- an international, multicenter cohort study 
    Jonas, Jan Philipp; Muller, Philip Christoph; Linecker, Michael; Hackl, Hubert; Santol, Jonas; Eshmuminov, Dilmurodjon; Rossler, Fabian; Ammann, Markus; Ignatavicius, Povilas; Guidetti, Cristiano; Sander, Sophia; Ardiles, Victoria; Wen, Zhang; Romic, Ivan; Fronek, Jiri; Kysela, Marek; Truant, Stephanie; Oldhafer, Karl; Reese, Tim; Rauchfuss, Falk; Ulmer, Tom Florian; Wahba, Roger; Hahn, Oszkar; Di Benedetto, Fabrizio; Fernandez-Placencia, Ramiro; Robles-Campos, Ricardo; Lopez, Victor; Sparrelid, Ernesto; Petrowsky, Henrik; Clavien, Pierre-Alain; Starlinger, Patrick (AME PUBLISHING COMPANY, 2025-10)
    BACKGROUND: Primarily unresectable liver tumors may be approached by the Associating Liver Partition and Portal vein Ligation for Staged Hepatectomy (ALPPS) procedure. Post-hepatectomy liver failure (PHLF) poses the most ...
  • Factors influencing the diagnostic basis in pancreatic cancer. A study within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort 
    Porta, Miquel; Pumarega, José; Giménez, Alex; Tjonneland, Anne; Chirlaque-López, María-Dolores; Sacerdote, Carlotta; Gasull, Magda; Olsen, Anja; Crous-Bou, Marta; Grioni, Sara; Truong, Therese; Dahmj, Christina-C; Colorado-Yohar, Sandra; Bouteille, Lea; Severi, Gianluca; Breeur, Marie; Saieva, Calogero; Guevara, Marcela; Panico, Salvatore; Tumino, Rosario; Sánchez, María-José; Dorronsoro, Ane; Ferrari, Pietro; Vineis, Paolo; Katzke, Verena (ELSEVIER, 2025)
    BACKGROUND AND AIMS: Substantial differences have been reported in risk estimates for etiologic factors of pancreatic cancer among subjects with different degrees of diagnostic certainty. The aim of the study was to assess ...
  • Protocol for quantifying extracellular and intracellular ATP from macrophages upon inflammasome activation using a luciferin-luciferase technique 
    Schachter, Julieta; Guijarro-Hernández, Adriana; Schwarzbaum, Pablo-J; Pelegrín, Pablo (CELL PRESS, 2025-12)
    Extracellular ATP triggers several cellular responses, while intracellular ATP depletion primes cells for death. Here, we present a protocol for the quantification of extracellular and intracellular ATP from bone marrow-derived ...
  • Heavy metals and trace elements in a threatened population of guanay cormorants (Leucocarbo bougainvilliorum) from an industrialized bay in the Humboldt Current System, Chile 
    Carretero, Jorge; García-Cegarra, Ana-M; Martínez-López, Emma (ELSEVIER GMBH, 2025-12)
    Metal contamination from industrial and mining activities threatens coastal and marine ecosystems, leading to bioaccumulation in marine organisms and biomagnification through the trophic chain. The Guanay cormorant (Leucocarbo ...
  • Estudio Delphi multidisciplinar sobre riesgo residual en pacientes con enfermedad renal crónica y diabetes mellitus tipo 2 
    Ortiz, Alberto; Cebrián-Cuenca, Ana-María; Soto, Alfonso; Reyes, Andrés; Gorriz, José-Luis (SOCIEDAD ESPAÑOLA DE NEFROLOGIA DR RAFAEL MATESANZ, 2025-08)
    BACKGROUND AND OBJETIVE: Currently, patients with chronic kidney disease (CKD) and type-2 diabetes mellitus (T2DM) present a persistent residual renal and cardiovascular (CV) risk despite receiving standard treatment. ...
  • The diagnostic efficiency of tissue factor pathway inhibitor 2 methylation in the detection of colorectal cancer: a systematic review and meta-analysis 
    Wang, Xiao-Ling; Qin, Shuo; Liu, Li; Jia, Yu-Qi; Wang, Ying; Zhou, Yu-Jie; Ramos-Molina, Bruno; Valladares-Ayerbes, Manuel; Eidens, Moritz; Liu, Zhi-Zhen (AME PUBLISHING COMPANY, 2025-06)
    BACKGROUND: Colorectal cancer (CRC) is a common malignant tumor of the digestive tract. Screening of high risk populations and early diagnosis of CRC are of great importance. Tissue factor pathway inhibitor 2 (TFPI2) ...
  • Transcriptomic Predictors of Survival for Palbociclib plus Endocrine Therapy Versus Capecitabine in Aromatase Inhibitor-Resistant Breast Cancer From the GEICAM/2013-02 PEARL Trial 
    Agrawal, Yash N.; Fernandez-Martinez, Aranzazu; Gil-Gil, Miguel; Zielinski, Christoph; Ruiz-Borrego, Manuel; Ciruelos, Eva Maria; Munoz, Montserrat; Margeli, Mireia; Bermejo, Begona; Anton, Antonio; Kahan, Zsuzsanna; Csoeszi, Tibor; Alonso-Romero, Jose Luis; Garcia-Saenz, Jose angel; Sanchez-Rovira, Pedro; Alvarez, Elena; Chacon, Jose Ignacio; Gonzalez-Santiago, Santiago; Rodriguez, Cesar A.; Servitja, Sonia; Pfefferle, Adam D.; Herranz, Jesus; Liu, Yuan; Carey, Lisa A.; Romero-Camarero, Isabel; Caballero, Rosalia; Guerrero-Zotano, Angel; Perou, Charles M.; Martin, Miguel (LIPPINCOTT WILLIAMS & WILKINS, 2025-07)
    PURPOSE: For hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) metastatic breast cancer (MBC), first-line cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) + endocrine therapy (ET) is ...
  • The COVID-19 vaccination health literacy questionnaire (CVHL-Q): Design and validation according to classic psychometric and Rasch analyses 
    Rodríguez-Blázquez, Carmen; Ayala, Alba; Bas-Sarmiento, Pilar; Fernández-Gutiérrez, Martina; Falcón-Romero, María; Romay-Barja, María; Joa, María (W B SAUNDERS CO LTD, 2025-10)
    OBJECTIVES: This study aimed to describe the COVID-19 vaccination health literacy questionnaire (CVHL-Q) and test its psychometric properties in the Spanish general population using Classic Test Theory (CTT) and Rasch ...
  • BO-112 Plus Pembrolizumab for Patients With Anti-PD-1-Resistant Advanced Melanoma: Phase II Clinical Trial SPOTLIGHT-203 
    Márquez-Rodas, Iván; Dutriaux, Caroline; Saiag, Philippe; de-la-Cruz-Merino, Luis; Castañon-Álvarez, Eduardo; Robert, Caroline; Rodríguez-Moreno, Juan-F; Arance, Ana; Cerezuela-Fuentes, Pablo; Montaudie, Henri; Fernández-de-Sanmamed-Girón, Miguel; González-Cao, María; Charles, Julie; López-Criado, María-Pilar; Berrocal, Alfonso; de-Miguel, Enrique; Funck-Brentano, Elisa; Prey, Sorilla; Álamo-de-la-Gala, María-del-Carmen; Melero, Ignacio; Avilés-Izquierdo, José-Antonio; Roman, Ruth; García-Pelaez, Beatriz; Rodríguez, Sonia; Trnkova, Zuzana-Jirakova; Quintero, Marisol; Macia, Sonia; Chaney, Marya-F; Dalle, Stephane (LIPPINCOTT WILLIAMS & WILKINS, 2025-09)
    PURPOSE: Patients with anti-PD-1-resistant melanoma (MEL) have no well-defined standard of care. BO-112 is a synthetic, double-stranded RNA (poly I:C) nanoplexed with polyethylenimine that when administered intratumorally ...
  • Magnitude of chronic kidney disease in Spain. 
    Santamaria, Rafael; Escobar, Carlos; Aranda, Unai; Palacios, Beatriz; Capel, Margarita; Hernández, Ignacio; Cebrián-Cuenca, Ana-María; Alcazar, Roberto; Gorostidi, Manuel (ELSEVIER, 2025-05)
  • Protein diversity, type 2 diabetes, and effect modifiers: a multi-country prospective study 
    Mozaffari, Hadis; Imamura, Fumiaki; Murphy, Rachel A.; Jessri, Mahsa; Sharp, Stephen J.; Forouhi, Nita G.; Wareham, Nicholas J.; Ibsen, Daniel B.; Dahm, Christina C.; Huerta, Jose Maria; Molina-Montes, Esther; Nickel, Daniela, V; Rolandsson, Olov; Sacerdote, Carlotta; Schulze, Matthias B.; Gonzalez-Martin, Jon Ander; Guevara, Marcela; Nilsson, Peter M.; Panico, Salvatore; Winkvist, Anna; Conklin, Annalijn, I (OXFORD UNIV PRESS, 2025-04-12)
    BACKGROUND: Dietary diversity may affect type 2 diabetes (T2D) but no studies have examined protein diversity by source. We examined five diversity scores and the 10-year risk of T2D and effect modification. METHODS: A ...
  • 10 key issues for prevention, monitoring and non-pharmacological treatment of delirium in critically ill patients 
    Valles-Fructuoso, Olga; Rodríguez-Mondéjar, Juan-José; Alonso-Crespo, David; Robleda-Font, Gemma; López-López, Candelas; Gil-Castillejos, Diana; Acevedo-Nuevo, María (ELSEVIER SCIENCE INC, 2025-04)
    In intensive care units, due to critical illness nature and environment special characteristics, it is relatively common for admitted patients to develop acute confusional syndrome (ACS) or delirium. The nurse's duties are ...
  • Evolving epidemiology of HCC in Spain 
    Sala, Margarita; Pascual, Sonia; Roca, Maria Rosa Rota; Rodriguez, Manuel; Chiminazzo, Valentina; Sala, Margarita; Pascual, Sonia; Roca, Maria Rosa Rota; Matilla, Ana Maria; Campos, Marta; Delgado, Manuel; Ferrerez, Maria Teresa; Montero, Jose Luis; Guerrero, Antonio; Aracil, Carles; Rodriguez-Lopez, Carlos; Sogbe, Miguel; Olmo, Javier Fuentes; Minguez, Beatriz; Vallejo-Senra, Nicolau; Unceta, Paloma Rendon; Clos, Ariadna; Diaz-Bethencourt, Dacil; Sanchez, Araceli Garcia; Castro, Raisa Quinones; Bustamante, Javier; Perello, Christie; Ponce, Juan Jose Urquijo; Serra, Hernan Andreu; Llamoza-Torres, Camilo Julio; Montoliu, Silvia; Fernandez-Marcos, Christina; Guiberteau, Ana; Vergara, Mercedes; Fernandez-Lopez, Alexia Maria; Gutierrez-Garcia, Maria Luisa; Hernaez-Alsina, Tania; Coll, Susana; Cuyas, Berta; Morillas, Maria Julia; Olmedo, Susana Rebolledo; Fernandez-Bermejo, Miguel; Roget, Merce; Ramos, Irina Calvo; Rio, Gemma Pacheco del; Rifa, Raimon; Gacho, Pilar Conde; Barrio, Monica Llorente; Gomez-Rubio, Mariano; Penas, Irene; Cachero, Alba; Reig, Maria; Gonzalez-Santiago, Jesus Manuel; Giraldez, Alvaro; Guerrero, Marta; Segarra, Jose Xavier; Romero-Gutierrez, Marta; Lledo, Jose Luis; Diaz-Gonzalez, Alvaro; Cortes-Garcia, Luis; Delgado, Carolina; Vazquez-Rodriguez, Sergio; Serra, Isabel; Inarrairaegui, Mercedes; Fernandez-Marcos, Cristina; Rodriguez-Gonzalez, Milagros; Barrio, Monica Llorente; Diaz-Bethencourt, Dacil; Lazaro, Maria; Bermudez-Ramos, Maria; Lue, Alberto; Molina, Esther; Macias-Rodriguez, Manuel Alberto; Varela, Maria (ELSEVIER, 2025-05)
    BACKGROUND & AIMS: The epidemiological landscape of hepatocellular carcinoma (HCC) in Europe is evolving. This study aims to provide an updated description of the current epidemiology of liver cancer in Spain. METHODS: ...
  • Evaluation of results from the ARGOS Program: prevention of alcohol, tobacco, and cannabis use in adolescents 
    Díaz-Cutillas, Mario; Espí-Ballester, Irene; Villar-Lorenzo, Ana-Belén; Puerta-Ortuño, Consuelo; López-Davis, Sylvia; Monteagudo-Piqueras, Olga; Medina-Infante, Berta-A (ELSEVIER, 2025)
    OBJECTIVE: To evaluate the impact of the ARGOS Community-Educational Program on reducing alcohol, tobacco, and cannabis use, resisting peer pressure to consume, and on increasing the perception of risk associated with ...
  • Illustrated capsules from the Advanced Course in Platelet Research 
    Buduo, Christian Andrea Di; Abbonante, Vittorio; Malara, Alessandro; Balduini, Alessandra; Waller, Amie K.; Watson, Steve P.; Martin, Eleyna M.; Bridge, Lloyd; Gibbins, Jonathan; Hers, Ingeborg; Masson, Claire; Eckly, Anita; Poulter, Natalie S.; Martinez-Garcia, Beatriz; Aguila, Sonia; Gresele, Paolo; Momi, Stefania; Amstrong, Paul; Rondina, Matthew; Troitino, Sara; Garcia, Angel; Bastida, Jose M.; Quilez, Ana Marin; Fuentes, Ana Sanchez; Rivera, Jose; Torres-Ruiz, Raul; Ojeda-Walczuk, Paula; Morgan, Neil, V; de la Morena, Belen; Ramaekers, Kato; Tran, My; De Wispelaere, Koen; Freson, Kathleen; Bergmeier, Wolfgang; Greinacher, Andreas; He, Fan; Oh, Stephen; Di Paola, Jorge; Semple, John W.; Lozano, Maria L.; Llamas, Pilar; Ward, Chris (ELSEVIER, 2025-02)
    This series of illustrated capsules summarizes the presentations made by the speakers at the first International Advanced Course in Platelet Research held in Murcia (Spain) from 27 to 28 September, 2024. This is the first ...
  • Spanish Registry of Renal Patients: 2022 Report and evolutive analysis 
    Quiroga, Borja; Mahillo, Beatriz; Mazuecos, Auxiliadora; Ortiz, Alberto; Comas-Farnes, Jordi; Hernández-Marrero, Domingo; Trujillo-Alemán, Sara; Santiuste-de-Pablos, Carmen; Rodríguez-Arévalo, Olga-Lucía; Marqués-Vidas, María; Slon-Roblero, M-Fernanda; Artamendi-Larrañaga, Marta; Moina-Eguren, Íñigo; Valentín-Muñoz, María-de-la-Oliva; Rodríguez-Camblor, Marta; Moreno-Alia, Inmaculada; Bouzas-Caamaño, M-Encarnación; Galan, M-Antonia-Blanco; Deira-Lorenzo, Javier; García-López, Héctor; Arribas-Monzon, Federico-Eduardo; Gómez-Marqués, Gonzalo; Rodríguez-Benot, Alberto; Domínguez-Gil, Beatriz; Álvarez, Emilio-Sanchez (SOCIEDAD ESPAÑOLA DE NEFROLOGIA DR RAFAEL MATESANZ, 2025-04)
    INTRODUCTION: Chronic kidney disease (CKD) will be the second leading cause of death in Spain by 2100. The Spanish Renal Disease Registry (REER) records the incidence, prevalence and mortality of all patients requiring ...

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