Repositorio Dspace

Envíos recientes

03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla): Envíos recientes

  • Computational flow cytometry immunophenotyping at diagnosis is unable to predict relapse in childhood B-cell Acute Lymphoblastic Leukemia. 
    Martínez-Rubio, Álvaro; Chulian, Salvador; Nino-López, Ana; Picon-González, Rocío; Rodríguez-Gutiérrez, Juan-F; Galvez-de-la-Villa, Eva; Caballero-Velazquez, Teresa; Molinos-Quintana, Agueda; Castillo-Robleda, Ana; Ramírez-Orellana, Manuel; Martínez-Sánchez, María-Victoria; Minguela-Puras, Alfredo; Fuster-Soler, José-Luis; Blázquez-Goni, Cristina; Pérez-García, Víctor-M; Rosa, María (ELSEVIER, 2025-04)
    B-cell Acute Lymphoblastic Leukemia is the most prevalent form of childhood cancer, with approximately 15% of patients undergoing relapse after initial treatment. Further advancements depend on novel therapies and more ...
  • MITF, TFEB, and TFE3 drive distinct adaptive gene expression programs and immune infiltration in melanoma 
    Dias, Diogo; Oliveira, Erica; Marti-Díaz, Roman; Andrews, Sarah; Chocarro-Calvo, Ana; Bellini, Alice; Mosteo, Laura; Vivas-García, Yurena; Chauhan, Jagat; Li, Linxin; García-Martínez, José-Manuel; Rodríguez-López, José-Neptuno; Maria-Engler, Silvya-Stuchi; Kenny, Colin; Martínez-Useros, Javier; García-Jiménez, Custodia; Sánchez-del-Campo, Luis; Louphrasitthiphol, Pakavarin; Goding, Colin-R (CELL PRESS, 2025-12)
    Cells can contain multiple related transcription factors targeting the same sequences, leading to potential regulatory cooperativity, redundancy, competition, or temporally regulated factor exchange. Yet, the differential ...
  • Seasonal influenza vaccination in childhood and adolescence. Consensus of the AEV, CAV-AEP and SEIP. 
    Álvarez-Aldean, Javier; Álvarez-García, Francisco-José; Cruz-Canete, Marta; Fernández-Prada, María; Francisco-González, Laura; Grande-Tejada, Ana-María; Iofrio-de-Arce, Antonio; Mendez-Sánchez, Alejandra; Moraga-Llop, Fernando; Salamanca-de-la-Cueva, Ignacio (ELSEVIER, 2025-10)
    Influenza is an important public health problem that puts healthcare systems to the test each year with outbreaks that constitute a significant social and economic burden. The proportion of the pediatric population affected ...
  • Eosinophils from jennies form extracellular traps (EETs) in vitro in response to seminal plasma: A new perspective on uterine immune defense in donkeys 
    Company, Sebastia; Robaina-Sancler-Silva, Yame-Fabres; Yanez-Ortiz, Iván; Martínez-Hernández, Jesús; Costa, Manuela; Catalán, Jaime; Miró, Jordi (ELSEVIER, 2025-11)
    Jennies exhibit a post-insemination uterine inflammatory response characterized by the infiltration of polymorphonuclear cells (PMNs), primarly neutrophils, followed by eosinophils and basophils. Neutrophils are known to ...
  • A Narrative Review of Twin Study Contributions to the Understanding of Sleep and Sleep Disorders 
    Madrid-Valero, Juan-José; Ordoñana, Juan-Ramón; Gregory, Alice-M (SPRINGERNATURE, 2025-05-17)
  • Outcomes of Kidney Transplants from Donors after Circulatory Death with Acute Kidney Injury: A Systematic Review 
    Trachsel, Carol; Kalt, Fabian; Jonas, Jan-Philipp; Rossler, Fabian; López-López, Víctor; Hubel, Kerstin; Schneider, Marcel; Kron, Philipp; Gerdes, Stephan; Stratta, Robert; Pei, Juan; Johnson, David; Boffa, Catherine; Abbas, Hussain; Schachtner, Thomas; Mueller, Nicolás-J; Kaplan, Bruce; Oberholzer, José; Eshmuminov, Dilmurodjon (SPRINGERNATURE, 2025-10-28)
  • Cost-Utility Analysis of FreeStyle Libre Systems in People with Type 2 Diabetes Mellitus on Treatment with Basal Insulin and Poor Glycemic Control in Spain 
    Robles-Plaza, Mireya; Gómez-Peralta, Fernando; Bellido, Virginia; Ampudia-Blasco, Francisco-Javier; Carretero-Gómez, Juana; Cebrián-Cuenca, Ana-María; de-la-Cuadra-Grande, Alberto; Mezquita-Raya, Pedro (SPRINGER HEIDELBERG, 2026-01)
    INTRODUCTION: FreeStyle Libre (FSL) systems are effective and user-friendly glucose monitoring devices. This cost-effectiveness analysis compared FSL vs. self-blood glucose monitoring (SBGM) in patients with poorly controlled ...
  • Dynamic Changes in Oxidative Stress and Epigenetic Modifications in the Ventral Mesencephalon and Striatum of MPTP-Treated Mice: Implications for Parkinson's Disease Pathogenesis 
    Gallo-Soljancic, Pablo; De-Stefano, María-Egle; González-Cuello, Ana-María; Fernández-Villalba, Emiliano; Godderis, Lode; Herrero, María-Trinidad (SPRINGER, 2025-08)
    This study investigates the effects of an acute 1-metil 4-fenil 1,2,3,6-tetraidro-piridina (MPTP) treatment, a known inducer of parkinsonism, on oxidative stress and epigenetic changes in the mouse ventral midbrain (VM) ...
  • Response rate and long-term survival in patients with advanced melanoma: data from the prospective cohort study gem-1801 
    Espinosa, Enrique; Berciano-Guerrero, Miguel-Ángel; Muñoz-Couselo, Eva; Puertolas, Teresa; Manzano, José-Luis; Soria, Ainara; Ayala-de-Miguel, Pablo; Crespo, Guillermo; Gutiérrez-Sanz, Lourdes; Cerezuela-Fuentes, Pablo; Aguado-de-la-Rosa, Carlos; Majem, Margarita; García-Castaño, Almudena; Berrocal, Alfonso; García-Arroyo, Francisco-Ramón; De-la-Borbolla, María-Rodriguez; Bellido, Lorena; Medina-Martínez, Javier; Fernández, Luis-Antonio; Martín-Carnicero, Alfonso; López-Castro, Rafael; Bujosa-Rodríguez, Aída; Jose-Lecumberri, Ma; Guzmán, José-Carlos-Villa; Campos-Balea, Begoña; Rodríguez, Joaquín-Fra; Valdivia-Bautista, Javier; Pérez, Víctor-Navarro; Mujika, Karmele; Corral-Subias, Mónica; Hernández, Berta; Martín-Algarra, Salvador; Márquez-Rodas, Iván (SPRINGER INT PUBL AG, 2025-11-28)
    PURPOSE: Anti-PD-1-based immunotherapy and targeted therapies (TT) are the current standard of care for patients with advanced melanoma. However, some patients die in less than a year from diagnosis and others become ...
  • Trends in the incidence of brain cancer and the use of mobile phones: analysis of the Spanish Network of Cancer Registries (REDECAN) 
    Galceran, Jaume; Ameijide, Alberto; Canete, Adela; Peris-Bonet, Rafael; López-de-Munain, Arantza; Aizpurua, Amaia; de-la-Cruz, Marta; Sanvisens, Arantza; Sánchez, María-José; Palacios, Isabel; Franch, Paula; Sánchez, Antonia; Guevara, Marcela; Carulla, María; Gutiérrez, Pilar; Sáez, Isabel; Rodríguez, Marta; Alemán, Araceli; Sabater, Consol (SPRINGER INT PUBL AG, 2025-05-14)
    PURPOSE: The association between the use of mobile phones use and the risk of brain cancer remains controversial. The aim of this study is to describe trends in the incidence of central nervous system (CNS) cancers in Spain ...
  • Immune checkpoint inhibitors-associated thrombosis in patients with head and neck cancer: a study of the Spanish society of medical oncology (SEOM) thrombosis and cancer group 
    Sánchez-Cánovas, Manuel; Moya-Hernández, Miguel-Ángel; Adoamnei, Evdochia; Cacho-Lavin, Diego; Fernández-Garay, David; Quintanar-Verduguez, Teresa; Rogado-Revuelta, Jacobo; García-Verdejo, Francisco-José; García-Adrián, Silvia; Ferrer-Pérez, Ana-Isabel; Guirao-García, María-Esperanza; López-Robles, Javier; Mendiola-Olivares, Jaime; Muñoz-Martín, Andrés-Jesús (SPRINGER INT PUBL AG, 2024-06-21)
    PURPOSE: Both venous and arterial thrombotic events (VTE/AT) can be associated with Immune Checkpoint Inhibitors (ICI). However, there is a paucity of information apropos patients in routine clinical practice. METHODS: ...
  • The use of oral anticoagulation at the time of acute COVID-19 infection and subsequent development of long-COVID/post-acute sequelae of SARS-CoV-2 infection 
    Frost, Freddy; Rivera-Caravaca, José-Miguel; Lip, Gregory-Y-H (SPRINGER, 2025-04-05)
    Long COVID (LC) or post-acute sequelae of SARS-CoV-2 infection (PASC) is defined as ongoing, relapsing or new symptoms/conditions persisting after an acute COVID-19 infection. Given the potential role of oral anticoagulants ...
  • Infection Spread and Outbreaks Support with Spatial-Temporal Visualization Tool for Hospitals 
    Kim, Denisse; Cánovas-Segura, Bernardo; Campos, Manuel; Alemán-Belando, Sergio; Juárez, José-Manuel (SPRINGER, 2025-06-18)
    Hospital-acquired infections (HAIs), especially those caused by multidrug-resistant bacteria, represent a critical challenge, increasing healthcare costs, hospital stays, and mortality rates. Monitoring HAIs requires ...
  • Novel Insights into the Clinical Features, Genetic Spectrum and Clonal Evolution of Patients Carrying NLRP3 Mosaicism 
    Bonet, Nuria; Mascaro, José-M; Hurtado-Navarro, Laura; Angosto-Bazarra, Diego; Callejas-Rubio, José-Luis; Clemente, Daniel; Souto, Alejandro; Lima, Olalla; Palmou-Fontana, Natalia; Baselga, Eulalia; Jiménez-Trevino, Santiago; Remesal, Agustin; Andreu-Barasoain, Marta; Fernández-Domínguez, Luis; Riera-Monroig, Josep; Aparicio, María; García-Herrero, Juan; Pesque, David; Sánchez-Calvin, María-Teresa; Lezana-Rosales, José-Miguel; Correyero-Plaza, María; García-Villalba, Julio; Bolano, Victor; Peiró, Sara; Díaz, Mar; Vlagea, Alexandru; Lorca, Daniel; Fabregat, Virginia; Anton, María-Carmen; Plaza, Susana; González-Granado, Luis-Ignacio; Postigo, Concepción; García-Ruiz-de-Morales, José-María; Gómez-de-la-Fuente, Enrique; Iglesias, Estibaliz; Gómez-Roman, Javier; Vázquez-Trinanes, Caritina; López-Robledillo, Juan-Carlos; Ortego-Centeno, Norberto; Giménez-Arnau, Ana-María; Campistol, Josep-M; Laayouni, Hafid; Ortiz-de-Landazuri, Iñaki; Yague, Jordi; González-Roca, Eva; Mensa-Vilaro, Anna; Fornas, Oscar; Ramos, Eduardo; Pelegrín, Pablo; Casals, Ferran; Arostegui, Juan-I (SPRINGER/PLENUM PUBLISHERS, 2025-12)
    NLRP3 mosaicism is a well-established mechanism causing the monogenic autoinflammatory disease named cryopyrin-associated periodic syndromes (CAPS). The number of reported patients with NLRP3 mosaicism is small, and the ...
  • Editorial Expression of Concern: Antinociceptive and antiedema effects produced in rats by Brassica oleracea var. italica sprouts involving sulforaphane 
    Guadarrama-Enriquez, Omar; Moreno-Pérez, Gabriel-Fernando; González-Trujano, María-Eva; Angeles-López, Guadalupe-Esther; Ventura-Martínez, Rosa; Díaz-reval, Irene; Cano-Martínez, Agustina; Pellicer, Francisco; Baenas, Nieves; Moreno, Diego-A; García-Viguera, Cristina (SPRINGER BASEL AG, 2026-02)
  • Cohort profile: the CORDELIA study (Collaborative cOhorts Reassembled Data to study mEchanisms and Longterm Incidence of chronic diseAses) 
    Hernaez, Álvaro; Camps-Vilaro, Anna; Polo-Alonso, Sara; Subirana, Isaac; Ramos, Rafel; de-Cid, Rafael; Rodríguez-Artalejo, Fernando; Elosua, Roberto; Chirlaque-López, María-Dolores; Amiano, Pilar; Bermúdez-López, Marcelino; Guevara, Marcela; Cinza-Sanjurjo, Sergio; Sánchez, María-José; Cabrera-de-León, Antonio; Laclaustra, Martin; Rojo-Martínez, Gemma; Guembe-Suescun, María-J; Pérez-Gómez, Beatriz; Vega-Alonso, Tomas; Toran-Monserrat, Pere; Lora-Pablos, David; Huerta-Castaño, José-María; Valdivielso, José-M; Degano, Irene-R; Felix-Redondo, Francisco-J; Gandarillas, Ana-María; Valdés, Sergio; Mundet-Tuduri, Xavier; Sánchez, Pedro-L; Martín-Sánchez, Vicente; Rigo, Fernando; Alonso-Sampedro, Manuela; Moreno-Iribas, Conchi; Martín-Escudero, Juan-Carlos; Delgado, Elias; Grau, María; Urrutia, Inés; Ovejero, Diana; Quintela, Inés; Marti-Lluch, Ruth; Blay, Natalia; Banegas, José-R; Tizon-Marcos, Helena; Gómez-Gómez, Jesús-Humberto; Aizpurua, Amaia; Castro-Boque, Eva; Delfrade, Josu; Prieto-Díaz, Miguel-Ángel; Rodríguez-Barranco, Miguel; Almeida-González, Delia; Moreno-Franco, Belén; Oualla-Bachiri, Wasima; Sayon-Orea, Carmen; Plans-Beriso, Elena; Lozano, José-Eugenio; López-Lifante, Víctor-M; Cancelas-Navia, Pilar; Cabrera-Castro, Natalia-Alejandra; Cambray, Serafi; Zacarias-Pons, Lluis; Fernández-Berges, Daniel; Donoso-Navarro, Encarnación; Maldonado-Araque, Cristina; Franch-Nadal, Josep; Dorado-Díaz, Pedro-Ignacio; Villarin-Castro, Alejandro; Frontera-Juan, Guillem; Gude, Francisco; Andueza, Naroa; Tellez-Plaza, María; Ares-Blanco, Jessica; Cruz, Raquel; Ribas-Aulinas, Marc; Barretina, Jordi; Guallar-Castillon, Pilar; Cainzos-Achirica, Miguel; Colorado-Yohar, Sandra; Llorente, Adrián; Díaz-Tocados, Juan-Miguel; Ardanaz, Eva; Mico-Pérez, Rafael-Manuel; Fernández-Martínez, Nicolás-Francisco; del-Cristo-Rodríguez-Pérez, María; Cenarro, Ana; Calle-Pascual, Alfonso-L; Marrugat, Jaume (SPRINGER, 2025-05)
    The CORDELIA Study (Collaborative Cohorts Reassembled Data to Study Mechanisms and Long-term Incidence of Chronic Diseases) combines 35 Spanish population cohorts to investigate the clinical, environmental, genetic, and ...
  • Assessing early therapeutic drug monitoring of adalimumab as a predictor of treatment efficacy and immunogenicity in rheumatic diseases: "early therapeutic drug monitoring of adalimumab" 
    Ortiz-Fernández, Patricia; Iniesta-Navalón, Carles; Urbieta-Sanz, Elena; Gascón-Cánovas, Juan-José (SPRINGER LONDON LTD, 2025-03)
    INTRODUCTION: Therapeutic drug monitoring (TDM) in inflammatory rheumatic diseases (RMDs) is gaining interest. However, there are unresolved questions about the best practices for implementing TDM effectively in clinical ...
  • Key steps of complex robotic liver surgery: an international expert survey 
    Aegerter, Noa-L-E; Kuemmerli, Christoph; Nickel, Felix; Guidetti, Cristiano; Tschuor, Christoph; López-López, Víctor; Wakabayashi, Taiga; Dutkowski, Philipp; Billeter, Adrian-T; Mueller, Beat-P; Mueller, Philip-C (SPRINGER, 2025-10)
    BACKGROUND: Robotic liver surgery (RLS) has become the preferred minimally invasive approach for liver surgery. However, especially for complex RLS (C-RLS), key surgical steps such as preoperative preparation, intraoperative ...
  • Ultrastructure of the epidermis and tube of two sessile species of the genus Limnias (Rotifera: Monogononta: Gnesiotrocha: Flosculariidae) 
    Franch-Meneu, Vicente; Pastor, Luis-Miguel (SPRINGER, 2025-08)
  • MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NF?B axis 
    García-Castillo, Jesús; Martínez-Cáceres, Carlos-Manuel; Bernabé-García, Manuel; Munitiz-Ruiz, Vicente; Ruiz-de-Angulo, David; Parrilla-Paricio, Pascual; Ortiz, Ángeles; Martínez-de-Haro, Luisa-Fernanda; Cayuela-Fuentes, María-Luisa (WILEY, 2025-11)
    Barrett's esophagus (BE) is a premalignant lesion that can lead to an invasive esophageal adenocarcinoma (EAC), a type of cancer that usually has a poor outcome. We have previously described a set of four microRNAs (miR-192, ...

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