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Envíos recientes

03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla): Envíos recientes

  • A novel chimeric antigen receptor T-cell therapy targeting CD84 for the treatment of acute myeloid and T-cell lymphoblastic leukemias 
    Pérez-Amill, Lorena; Armand-Ugon, Mercedes; Val-Casals, María; Martín-Herreros, Beatriz; Álamo, José-R; Peña, Sergio; Frigola, Gerard; Altuna, Ane; Santos, Claudio; Guijarro, Francesca; Minguela-Puras, Alfredo; Bataller, Alex; Casanovas-Alberti, Berta; Uribe-Herranz, Mireia; Navarro, Irene; Guerreiro, Manuel; Sánchez-Martínez, Diego; Tirado, Nestor; Velasco-Hernández, Talia; Menéndez, Pablo; Martínez, Antonio; Rovira, Montse; Colomer, Dolors; González-Navarro, Europa-Azucena; Esteve, Jordi; Urbano-Ispizua, Álvaro; Montesinos, Pau; Delgado, Julio; Juan, Manel; Klein-González, Nela (SPRINGERNATURE, 2025-10)
    Despite the remarkable clinical successes of chimeric antigen receptor (CAR) T-cell therapies in treating B-cell malignancies and multiple myeloma, similar outcomes have not been achieved in other indications. For patients ...
  • Non canonical c-CBL mutations define a specific phenotype of myeloid neoplasia 
    Guarnera, Luca; Gurnari, Carmelo; Bravo-Pérez, Carlos; Durmaz, Arda; Williams, Nakisha-D; Awada, Hussein; Kawashima, Naomi; Ahmed, Arooj; Unlu, Serhan; Ogbue, Olisaemeka-D; Haddad, Christopher; Mandala, Aashray; Kubota, Yasuo; Bodo, Juraj; Crane, Genevieve-M; Rogers, Heesun-J; Maciejewski, Jaroslaw-P; Visconte, Valeria (SPRINGERNATURE, 2025-03)
  • Photoactivatable Cyclometalated Ir(III) Compound Penetrates the Blood-Brain Barrier in 3D Spheroidal and Advanced 3D Organoid Models of Inherently Resistant and Aggressive Brain Tumors 
    Novohradsky, Vojtech; Marco, Alicia; Svitelova, Marie; Cutillas-Aulló, Natalia; Ruiz, José; Brabec, Viktor (AMER CHEMICAL SOC, 2025-07-11)
    The blood-brain barrier represents a significant challenge in delivering anticancer drugs for glioblastoma treatment. The study investigates the potential of a series of octahedral photoactivatable cyclometalated iridium ...
  • Novel Insights into the Human Gut Microbially Conjugated Bile Acids: The New Diversity of the Amino Acid-Conjugated Derivatives 
    García, Carlos-J; García-Villalba, Rocío; Frutos-Lison, María-D; Beltran, David; Martínez-Sánchez, María-Antonia; Núñez-Sánchez, María-Ángeles; Ramos-Molina, Bruno; Tomas-Barberan, Francisco-A (AMER CHEMICAL SOC, 2025-08-06)
    Bile acids (BAs) are biomolecules involved in lipids and glucose metabolism, and recently discovered microbially conjugated BAs (MCBAs) play an important role. Although the production of MCBAs amidated with amino acids ...
  • Lifetime Swimming Pool Attendance and Cancer Risk: Findings from the Multicase-Control Study in Spain (MCC-Spain) 
    Donat-Vargas, Carolina; Vallbona-Vistos, Miquel; Castaño-Vinyals, Gemma; Moreno, Victor; Aragonés, Nuria; Boldo, Elena; Molina-de-la-Torre, Antonio-José; Gómez-Acebo, Inés; Guevara, Marcela; Jiménez-Zabala, Ana; Amiano, Pilar; Molina-Barceló, Ana; Fernández-Tardon, Guillermo; Chirlaque-López, María-Dolores; Pollan, Marina; Kogevinas, Manolis; Villanueva, Cristina-M (AMER CHEMICAL SOC, 2025-11-18)
    Swimming in pools involves inhalation and skin absorption of potential carcinogenic disinfection byproducts (DBPs) as well as physical activity, which is protective for some cancer sites. We evaluated the association between ...
  • Barriers and competencies in nursing care for diabetic foot management: a mixed-methods observational study 
    Rodríguez-Valiente, Mónica; Martínez-Alcaraz, Roberto-Carlos; Sánchez-Galvez, Javier; Mateo-Ramírez, Francisco; Baño-Egea, Juan-Jesús; Solé-Agustí, Maria-Cristina; Pereda-Mas, Arturo; Beteta-Fernández, María-Dolores (CAMBRIDGE UNIV PRESS, 2026)
    AIM: To explore nurses' perceptions regarding their knowledge, degree of autonomy, and the difficulties encountered in managing diabetic foot in Primary Care. BACKGROUND: Diabetes mellitus is a chronic condition with a ...
  • Monitoring effectiveness of nirsevimab immunization against RSV hospitalization using surveillance data: a test-negative case-control study, Spain, October 2024-March 2025 
    Campos-Mena, Sandra; Pérez-Gimeno, Gloria; Lorusso, Nicola; Álvarez-Rio, Virginia; Basile, Luca; Batalla-Rebollo, Noa; García-Comas, Luis; Andreu-Ivorra, Blanca; Pérez-Panades, Jordi; Ramos-Marin, Violeta; Castrillejo, Daniel; Fernández-Ibáñez, Ana; Rafael-de-la-Cruz-López, María-Ángeles; Núñez, Olivier; Monge, Susana (CAMBRIDGE UNIV PRESS, 2026)
    Effectiveness of nirsevimab against respiratory syncytial virus (RSV) hospitalization during the 2024/2025 season in Spain was estimated using a test-negative design (TND) and hospital-based respiratory infections surveillance ...
  • Reflections on the I-squared index for measuring inconsistency in meta-analysis 
    Higgins, Julian-P-T; López-López, José-Antonio (CAMBRIDGE UNIV PRESS, 2025-12-29)
  • Interleukin-6 supplementation during in vitro maturation improves developmental competence of in vitro fertilized porcine oocytes 
    García-Cánovas, Manuela; López-Jara, Adelina; González-Plaza, Alejandro; Parrilla, Inmaculada; Rodríguez-Martínez, Heriberto; Cuello, Cristina; Martínez, Emilio-A; Gil, María-Antonia (ELSEVIER SCIENCE INC, 2025-09)
    Interleukin 6 (IL-6) is a cytokine physiologically expressed within the reproductive tract, where it plays a crucial role in cellular communication and processes such as ovulation and implantation. These processes and the ...
  • Deciphering immune tolerance in allogeneic pig pregnancy 
    Cambra, Josep-M; Martínez-Serrano, Cristina-A; Rodríguez-Martínez, Heriberto; Vázquez, Juan-M; Cuello, Cristina; Gil, María-Antonia; Martínez, Emilio-A; Parrilla, Inmaculada (ELSEVIER SCIENCE INC, 2025-05)
    Embryo transfer (ET) has transformed swine biotechnology, enabling genetic advancements and disease control. However, its success remains inconsistent, partly due to immune-mediated challenges at the maternal-fetal interface. ...
  • Characterization of decellularized porcine oviduct- and uterine-derived scaffolds evaluated by spermatozoa-based biocompatibility and biotoxicity 
    Martínez-López, Cristina; Martínez-Cáceres, Carlos-Manuel; Cortina-Navarro, María; Izquierdo-Rico, María-José; García-Vázquez, Francisco-Alberto (ELSEVIER SCIENCE INC, 2025-01)
    Decellularized extracellular matrix (dECM) are widely utilized in regenerative medicine and tissue engineering due to their ability to promote cell growth, proliferation, and differentiation. In reproduction, research is ...
  • Implications of different hypothermic preservation conditions on boar sperm quality during storage: Evaluation in sperm-rich fraction and whole ejaculate 
    Grudzinska, Paulina; Luongo, Chiara; Quintero-Moreno, Armando; García-Vázquez, Francisco-Alberto (ELSEVIER SCI LTD, 2025-12)
    Low-temperature storage of boar semen is a promising alternative to antibiotics in artificial insemination (AI), helping reduce antimicrobial resistance. However, optimal handling protocols remain undefined, especially ...
  • Breast cancer incidence, by stage at diagnosis, and mortality in 21 European countries in the era of mammography screening: an international population-based study 
    Cardoso, Rafael; Ola, Idris; Jansen, Lina; Hackl, Monika; Ihle, Petra; Francart, Julie; Van-Damme, Nancy; Valerianova, Zdravka; Atanasov, Trayan; Majek, Ondrej; Ngo, Ondrej; Innos, Kaire; Magi, Margit; Yonli, Sandrine-Dabakuyo; Woronoff, Anne-Sophie; Tretarre, Brigitte; Poncet, Florence; Katalinic, Alexander; Walsh, Paul-M; Vincerz, Ieva; Steponaviciene, Laura; De-Munck, Linda; Siesling, Sabine; Johannesen, Tom-Borge; Hofvind, Solveig; Calisto, Rita; Bento, María-José; Da-Costa, Filipa-Alves; Mayer, Alexandra; Lourenco, Antonio; Zagar, Tina; Tomsic, Sonja; Rodríguez-Barranco, Miguel; Sánchez, María-José; López-de-Munain-Marqués, Arantza; Marcos-Gragera, Rafael; Sanvisens, Arantza; Sánchez-Gil, Antonia; Chirlaque-López, María-Dolores; Galceran, Jaume; Saladie, Francina; Sundquist, Kristina; Sundquist, Jan; Persson, Mats-Ake; Blum, Marcel; Mousavi, Mohsen; Von-Moos, Roger; Sumkina, Olena; Ryzhov, Anton; Hoffmeister, Michael; Brenner, Hermann (ELSEVIER, 2026-03)
    BACKGROUND: Mammography screening programmes have been widely implemented across European countries over the past 40 years with the main aim to detect breast cancer earlier and thereby reduce breast cancer mortality. This ...
  • Associations between degree of food processing and all-cause and cause-specific mortality: a multicentre prospective cohort analysis in 9 European countries 
    González-Gil, Esther-M; Matta, Michele; Morales-Berstein, Fernanda; Cairat, Manon; Nicolás, Genevieve; Blanco, Jessica; Kliemann, Nathalie; Levy, Renata-Bertazzi; Rauber, Fernanda; Jacobs, Inarie; Al-Nahas, Aline; Cakmak, Emine-Koc; Vamos, Eszter-P; Chang, Kiara; Yammine, Sahar-G; Millett, Christopher; Touvier, Mathilde; Matias-Pinho, María-Gabriela; Tsilidis, Konstantinos-K; Heath, Alicia-K; Lill, Christina-M; Pala, Valeria; Moreno-Iribas, Conchi; De-Magistris, María-Santucci; Dahm, Christina-C; Bock, Niels; Olsen, Anja; Tjonneland, Anne; van-der-Schouw, Yvonne-T; Amiano, Pilar; Jannasch, Franziska; Schulze, Matthias-B; Mancini, Francesca-Romana; Marques, Chloe; Cadeau, Claire; Bonet, Catalina; Redondo-Sánchez, Daniel; Borch, Kristin-Benjaminsen; Brustad, Magritt; Skeie, Guri; Gómez-Gómez, Jesús-Humberto; Macciotta, Alessandra; Ferrari, Pietro; Dossus, Laure; Gunter, Marc-J; Huybrechts, Inge (ELSEVIER, 2025-03)
    BACKGROUND: Ultra-processed food (UPF) consumption has been linked with higher risk of mortality. This multi-centre study investigated associations between food intake by degree of processing, using the Nova classification, ...
  • Evaluation of alignment methods to support the assessment of similarity between e-commerce knowledge graphs 
    Almagro-Hernández, Gines; Mulero-Hernández, Juan; Deshmukh, Prashant; Bernabé-Díaz, José-Antonio; Sánchez-Fernández, José-Luis; Espinoza-Arias, Paola; Mueller, Juergen; Fernández-Breis, Jesualdo-Tomás (ELSEVIER, 2025-04)
  • First record of trace elements in cetaceans stranded along the Asturias Coastline, Northwest Spain: One great diversity area of marine mammals 
    Banos-Domenech, L; García-García, N; Peñalver, J; Armenteros, J-A; Martínez-López, E (ELSEVIER GMBH, 2025-06)
    The concentrations of cadmium (Cd), lead (Pb), arsenic (As), selenium (Se) and mercury (Hg) in the kidney, liver, brain and muscle of 20 individuals of cetaceans, stranded along the Asturias coastline between 2018 and 2020, ...
  • Poor clinical outcomes associated to multimorbidity, frailty and malnutrition in patients with atrial fibrillation. 
    Soler-Espejo, Eva; Zazo-Luengo, Beatriz-Angela; Rivera-Caravaca, José-Miguel; López-Gavez, Raquel; Esteve-Pastor, María-Asunción; Lip, Gregory-Y-H; Marín, Francisco; Roldán-Schilling, Vanessa (ELSEVIER, 2025-01)
    BACKGROUND: Atrial fibrillation (AF) patients often present with a higher prevalence of comorbidities, frailty, and malnutrition. We investigated if multimorbidity, frailty and malnutrition were associated with clinical ...
  • Loss of Cdkn1a protects against MASLD alone or with alcohol intake by preserving lipid homeostasis 
    Lamas-Paz, Arantza; Hionides-Gutiérrez, Alejandro; Guo, Feifei; Jorquera, Gonzalo; Moran-Blanco, Laura; Benede-Ubieto, Raquel; Mesquita, Mariana; Estevez-Vázquez, Olga; Zheng, Kang; Mazariegos, Marina; Vázquez-Ogando, Elena; Blázquez-López, Elena; Asensio, Iris; Mutlu, Beste; Gómez-Santos, Beatriz; Peligros, María-Isabel; Vaquero, Javier; Banares, Rafael; Delgado, Teresa-C; Martínez-Chantar, María-Luz; Martínez-Naves, Eduardo; Sanz-García, Carlos; Mohamed, Mohamed-Ramadan; Tesolato, Sofia; Iniesta, Pilar; Gallego-Duran, Rocío; Maya-Miles, Douglas; Ampuero, Javier; Romero-Gómez, Manuel; Martínez-Alcocer, Ana; Sanfeliu-Redondo, David; Fernández-Iglesias, Anabel; Gracia-Sancho, Jordi; Coll, Mar; Graupera, Isabel; Gines, Pere; Ciudin, Andrea; Rivera-Esteban, Jesús; Pericas, Juan-M; Ávila, Matias-A; Frutos-Bernal, María-Dolores; Martínez-Cáceres, Carlos-Manuel; Ramos-Molina, Bruno; Aspichueta, Patricia; Puigserver, Pere; Nevzorova, Yulia-A; Cubero, Francisco-Javier (ELSEVIER, 2025-01)
    BACKGROUND & AIMS: Expression of P21, encoded by the CDKN1A gene, has been associated with fibrosis progression in steatotic liver disease (SLD); however, the underlying mechanisms remain unknown. In the present study, we ...
  • Microbial catabolism of coffee pulp (poly)phenols during in vitro colonic fermentation 
    Canas, Silvia; Tosi, Nicole; Núñez-Gómez, Vanesa; Del-Rio, Daniele; Mena, Pedro; Martín-Cabrejas, María-A; Aguilera, Yolanda (ELSEVIER SCI LTD, 2025-01)
    Coffee pulp is a by-product characterized by its richness in phenolic compounds. This study examined the catabolism of (poly)phenols in digested coffee pulp flour (CPF) and extract (CPE) during in vitro colonic fermentation. ...
  • Ontology Coverage Analysis through Language Models 
    Abad-Navarro, Francisco; Martínez-Costa, Catalina; Fernández-Breis, Jesualdo-Tomás (PERGAMON-ELSEVIER SCIENCE LTD, 2025-12)

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