Repositorio Dspace

Envíos recientes

03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla): Envíos recientes

  • Monolobated megakaryocytes and ring sideroblasts: A morphological prelude to multihit TP53 and complex karyotype 
    Marco-Ayala, Javier; Chen-Liang, Tzu-Hua; Ortuño, Francisco-José; Lozano-Almela, María-Luisa (WILEY, 2026-01)
  • Insights into the clinical, platelet and genetic landscape of inherited thrombocytopenia with malignancy risk 
    Marín-Quílez, Ana; Sánchez-Fuentes, Ana; Zamora-Cánovas, Ana; Gómez-González, Pedro-Luis; Díaz-Ajenjo, Lorena; Benito, Rocío; Rodríguez-Alen, Agustin; Sevivas, Teresa; Murciano, Thais; Murillo, Laura; Butta, Nora-V; Revilla, Nuria; Campos, Rosa; Escribano, Paola; Esteve, Jordi; Fernández-Mosteirin, Nuria; Ferrer-Marín, Francisca; Hernández, Laura; Huerta-Aragones, Jorge; León, Antonio; López-Duarte, Mónica; López, Eugenia; Martín-Salces, Mónica; Nomdedeu, Meritxell; Ona, Raquel; Peláez-Pleguezuelos, Irene; Ramos, Fernando; Sebastián, Elena; Serrano-Jara, Claudia; Sierra-Aisa, Cristina; Vidal-Laso, Rosa; González-Porras, José-Ramón; Lozano-Almela, María-Luisa; Bastida, José-María; Rivera, José (WILEY, 2025-10)
    Inherited thrombocytopenia (IT) with germline variants in RUNX1, ETV6 or ANKRD26 carries a high risk (10%-45%) of developing haematological malignancy (IT-HM). We evaluated the clinical, platelet and molecular characteristics ...
  • Anti-thymocyte globulin in immune-mediated cytopenias: A monocentric experience and literature review 
    Guarnera, Luca; Ahmed, Arooj; Bravo-Pérez, Carlos; Ogbue, Olisaemeka-D; D'Addona, Matteo; Brady, Zachary; Unlu, Serhan; Haddad, Christopher; Mandala, Aashray; Durmaz, Arda; Gurnari, Carmelo; Visconte, Valeria; Maciejewski, Jaroslaw-P (WILEY, 2025-07)
    Anti-thymocyte globulin in multi-refractory immune-mediated cytopenia is an effective treatment, with response rate as high as 65%. Younger patients, presenting with thrombocytopenia or neutropenia, and those with LGL and ...
  • Pig Seminal Plasma Extracellular Vesicles Enhance Motility During Preservation of Epididymal Spermatozoa but Impair Capacitation and IVF Parameters 
    Moya-Fernández, Ana; Toledo-Guardiola, Santa-María; Silke, Peter; Navarro-Serna, Sergio; Matas-Parra, Carmen (WILEY, 2025-12)
    BACKGROUND: Extracellular vesicles (EVs) produced by accessory sex glands play a key role in sperm functionality, influencing motility, viability, acrosome integrity, metabolic activity, and capacitation. Most studies on ...
  • The Oxytocin Receptor in Spermatozoa May Originate From Both Spermatogenesis and Epididymal Maturation, and Regulates Capacitation 
    Martínez-Hernández, Jesús; Garriga, Ferran; Ahmad, Adeel; Padilla, Lorena; Maside, Carolina; Bonet, Sergi; Barranco-Boada, María-Isabel; Roca, Jordi; Pastor, Luis-Miguel; Yeste, Marc (WILEY, 2026-03)
    BACKGROUND: The oxytocin receptor (OR) is a G-protein-coupled receptor recently identified in human spermatozoa, whose origin and role in sperm physiology remain unknown. OBJECTIVES: In this study, using the pig as a model, ...
  • Development of a Short Telomere Zebrafish Model for Accelerated Aging Research and Antiaging Drug Screening 
    Hernández-Silva, David; López-Abellán, María-Dolores; Martínez-Navarro, Francisco-J; García-Castillo, Jesús; Cayuela-Fuentes, María-Luisa; Alcaraz-Pérez, Francisca (WILEY, 2025-06)
    Increased life expectancy is associated with a higher risk of age-related diseases, which represent a major public health challenge. Animal models play a crucial role in aging research, enabling the study of diseases at ...
  • Discovering Genetic Variants in Hypertrophic Cardiomyopathy With Multiple Machine Learning Techniques 
    Lozano-Paredes, Dafne; Bote-Curiel, Luis; Sabater-Molina, María; Bielza, Concha; Gimeno-Blanes, Juan-Ramón; Muñoz-Romero, Sergio; Gimeno-Blanes, F-Javier; Larrañaga, Pedro; Rojo-Álvarez, José-Luis (IEEE COMPUTER SOC, 2025-07)
    Hypertrophic cardiomyopathy is known to have strong genetic foundations. However, only some studies have addressed the complex network of co-expressed genes and variants that modify the phenotype. Machine learning methods ...
  • Three-year survival follow-up of patients with gastrointestinal cancer treated during the COVID-19 pandemic in Spain: data from the PANDORA-TTD20 study 
    García-Alfonso, Pilar; Jiménez-Fonseca, Paula; Soto-Alsar, Javier; Baraibar, Iosune; Santos, Cristina; La-Casta, Adelaida; Ghanem, Ismael; Pulido-Cortijo, Gema; Marino-Mendez, Axel; Pazo-Cid, Roberto; Vera, Ruth; Melian, Marcos; Alcaide, Julia; Grana, Begoña; Paez, David; Gallego, Inmaculada; Lobo-de-Mena, Miriam; Borregón-Rivilla, Miguel; Fernández-Montes, Ana; Martínez-de-Castro, Eva; Carmona-Bayonas, Alberto; Aranda, Enrique (OXFORD UNIV PRESS, 2025-08-04)
    INTRODUCTION: The initial SARS-CoV-2 pandemic wave in Spain in 2020 precipitated significant paradigm shifts in gastrointestinal oncology patient management. This study captures the "Zeitgeist" of this period by analyzing ...
  • Kidney replacement therapy for men and women according to the ERA Registry and the USRDS 
    Stel, Vianda-S; Chesnaye, Nicholas-C; Boenink, Rianne; Boerstra, Brittany-A; Astley, Megan-E; Methven, Shona; Heylen, Line; Resic, Halima; Ten-Dam, Marc-A-G-J; Hommel, Kristine; Solbu, Marit-D; Slon-Roblero, María-F; Areste-Fosalba, Nuria; Radunovic, Danilo; García-López, Héctor; Buchwinkler, Lukas; Guidotti, Rebecca; Lassalle, Mathilde; Santiuste-de-Pablos, Carmen; Stendahl, María; Indridason, Olafur-S; Escriba, Almudena; Bouzas-Caamano, María-Encarnación; Rodríguez-Arévalo, Olga-Lucía; Moustakas, George; Hernández-Vargas, Hermann; Ortiz, Alberto; Kramer, Anneke (OXFORD UNIV PRESS, 2025-10-31)
    BACKGROUND: This paper compares the incidence and prevalence of kidney replacement therapy (KRT), kidney transplantation rates, and mortality on KRT between Europe and the United States (US), including sex comparisons. ...
  • Inherited kidney disease and CAKUT are common causes of kidney failure requiring kidney replacement therapy: an ERA Registry study 
    Ortiz, Alberto; Kramer, Anneke; Ariceta, Gema; Rodríguez-Arévalo, Olga-Lucía; Gjerstad, Ann-C; Santiuste-de-Pablos, Carmen; Trujillo-Alemán, Sara; Ferraro, Pietro-Manuel; Methven, Shona; Santamaria, Rafael; Naumovic, Radomir; Resic, Halima; Hommel, Kristine; Segelmark, Marten; Ambuehl, Patrice-M; Sorensen, Soren-S; Parmentier, Cyrielle; Vidal, Enrico; Bakkaloglu, Sevcan-A; Plumb, Lucy; Palsson, Runolfur; Kerschbaum, Julia; ten-Dam, Marc-A-G-J; Stel, Vianda-S; Jager, Kitty-J; Torra, Roser (OXFORD UNIV PRESS, 2025-04-28)
    BACKGROUND: Inherited kidney diseases (IKDs) and congenital anomalies of the kidney and urinary tract (CAKUT) are causes of kidney failure requiring kidney replacement therapy (KRT) that major renal registries usually ...
  • Reassessing the association between age at menarche and cardiovascular disease: observational and Mendelian randomization analyses 
    Tschiderer, Lena; Peters, Sanne-A-E; van-der-Schouw, Yvonne-T; Burgess, Stephen; Luijken, Janneke; Bijmolt, Cheyenne; Soliman, Houda; Butterworth, Adam-S; Wood, Angela-M; Tong, Tammy-Y-N; Dahm, Christina-C; Seekircher, Lisa; Tjonneland, Anne; Mellemkjaer, Lene; Schulze, Matthias-B; Masala, Giovanna; Sieri, Sabina; Panico, Salvatore; Sacerdote, Carlotta; Boer, Jolanda-M-A; Verschuren, W-M-Monique; Castro-Espín, Carlota; Petrova, Dafina; Colorado-Yohar, Sandra; Moreno-Iribas, Conchi; Weiderpass, Elisabete; Heath, Alicia-K; Tzoulaki, Ioanna; Willeit, Peter; Onland-Moret, N-Charlotte (OXFORD UNIV PRESS, 2025-03-18)
    AIMS: Observational studies have shown a U-shaped association between age at menarche (AAM) and cardiovascular disease (CVD). We assessed non-linearity of the observational association and the potential causal relationship ...
  • Association between comorbidity burden and outcomes of catheter ablation vs. medical therapy for atrial fibrillation: insights from the CABANA trial 
    Chen, Yang; Soler-Espejo, Eva; Zhao, Manlin; Li, Wenhui; Liu, Hongyu; Gue, Ying; McDowell, Garry; Packer, Douglas-L; Lip, Gregory-Y-H (OXFORD UNIV PRESS, 2025-12-01)
    AIMS: Multimorbidity frequently coexists with atrial fibrillation (AF) and complicates treatment decisions. While current guidelines offer selective recommendations for catheter ablation in this group, evidence remains ...
  • Association of circulating fatty acids with cardiovascular disease risk: analysis of individual-level data in three large prospective cohorts and updated meta-analysis 
    Shi, Fanchao; Chowdhury, Rajiv; Sofianopoulou, Eleni; Koulman, Albert; Sun, Luanluan; Steur, Marinka; Aleksandrova, Krasimira; Dahm, Christina-C; Schulze, Matthias-B; van-der-Schouw, Yvonne-T; Agnoli, Claudia; Amiano, Pilar; Boer, Jolanda-M-A; Bork, Christian-S; Cabrera-Castro, Natalia-Alejandra; Eichelmann, Fabian; Elbaz, Alexis; Farras, Marta; Heath, Alicia-K; Kaaks, Rudolf; Katzke, Verena; Keski-Rahkonen, Pekka; Masala, Giovanna; Moreno-Iribas, Conchi; Panico, Salvatore; Papier, Keren; Petrova, Dafina; Quiros, J-Ramon; Ricceri, Fulvio; Severi, Gianluca; Tjonneland, Anne; Tong, Tammy-Y-N; Tumino, Rosario; Wareham, Nicholas-J; Weiderpass, Elisabete; Di-Angelantonio, Emanuele; Forouhi, Nita-G; Danesh, John; Butterworth, Adam-S; Kaptoge, Stephen (OXFORD UNIV PRESS, 2025-02-18)
    AIMS: Associations of saturated and unsaturated fatty acids (FAs) with cardiovascular disease (CVD) remain controversial. We therefore aimed to investigate the prospective associations of objectively measured FAs with CVD, ...
  • Deciphering differences in DNA methylation and transcriptome profiles of oocytes from pigs with high and low developmental competence 
    Abril-Parreño, Laura; Lopes, Jordana-Sena; Romero-Aguirregomezcorta, Jon; Galvao, Antonio; Kelsey, Gavin; Coy-Fuster, Pilar (OXFORD UNIV PRESS, 2025-01-22)
    In vitro maturation (IVM) is a critical step in animal in vitro embryo production, yet oocytes matured in vitro often exhibit lower developmental competence than their in vivo counterparts. However, the molecular mechanisms ...
  • Persistent progression independent of relapse activity in multiple sclerosis 
    Zhu, Chao; Zhou, Zhen; Kalincik, Tomas; Roos, Izanne; Buzzard, Katherine; Skibina, Olga; Alroughani, Raed; Kuhle, Jens; Girard, Marc; Grammond, Pierre; Lechner-Scott, Jeannette; Gerlach, Oliver; John, Nevin; McCombe, Pamela; Macdonell, Richard; van-Pesch, Vincent; Laureys, Guy; Prevost, Julie; Horakova, Dana; Kubala-Havrdova, Eva; Castillo-Trivino, Tamara; Ramo-Tello, Cristina; Blanco, Yolanda; Meca-Lallana, José-Eustasio; Lugaresi, Alessandra; Tomassini, Valentina; Cartechini, Elisabetta; Amato, María-Pia; Spitaleri, Daniele; Patti, Francesco; Maimone, Davide; Foschi, Matteo; Surcinelli, Andrea; D'Amico, Emanuele; Yamout, Bassem; Khoury, Samia-J; Jose-Sa, María; Boz, Cavit; Ozakbas, Serkan; Weinstock-Guttman, Bianca; Merlo, Daniel; Monif, Mastura; Jokubaitis, Vilija-G; van-der-Walt, Anneke; Butzkueven, Helmut (OXFORD UNIV PRESS, 2025-09-01)
    Patients with relapsing-remitting multiple sclerosis (RRMS) may experience disability progression independent of relapse activity (PIRA), which can be an early sign of secondary progressive MS (SPMS). We defined persistent ...
  • The Brescia internationally validated European guidelines on minimally invasive liver surgery 
    Abu-Hilal, Mohammad; Hoogteijling, Tijs-J; Edwin, Bjorn; Dagher, Ibrahim; D'Hondt, Mathieu; Marqués, Hugo-P; Swijnenburg, Rutger-Jan; Boggi, Ugo; Sucandy, Iswanto; Ferrero, Alessandro; Marsman, Hendrik; I; Gumbs, Andrew-A; Aldrighetti, Luca-A; Cherqui, Daniel; Alseidi, Adnan; Croner, Roland; Rotellar, Fernando; Scatton, Olivier; Al-Saati, Hani; Berardi, Giammauro; Cillo, Umberto; Cipriani, Federica; Ciria, Rubén; Cugat, Esteban; Di-Benedetto, Fabrizio; Díaz-Nieto, Rafael; Duncan, Trish; Efanov, Mikhail; Ettore, Giuseppe-M; Fondevila, Constantino; Fretland, Asmund-A; Giuliante, Felice; Hagendoorn, Jeroen; Han, Ho-Seong; Honda, Goro; Lesurtel, Mickael; Lodge, Peter; López-Ben, Santiago; Memeo, Riccardo; Menon, Krishna; Rashidian, Niki; Ratti, Francesca; Robles-Campos, Ricardo; Russolillo, Nadia; Ruzzenente, Andrea; Santoyo, Julio; Schmelzle, Moritz; Sgarbura, Olivia; Sutcliffe, Robert-P; Teh, Catherine-S-C; Vivarelli, Marco; Wakabayashi, Go; White, Steven; Pearce, Neil; Angelico, Roberta; Bannone, Elisa; Cacciaguerra, Andrea-Benedetti; Bozkurt, Emre; Conticchio, María; El-Adel, Soufyan; Famularo, Simone; Guerra, Martina; Kuemmerli, Christoph; López-López, Víctor; Pardo-Aranda, Fernando; Pilz-da-Cunha, Gabriela; Primavesi, Florian; Saeidi, Sara; Sheel, Andrea-R-G; Sijberden, Jasper-P; Sucameli, Francesco; Taliente, Francesco; Veronesi, Teodros; Ahmad, Jawad; Alfieri, Sergio; Ausania, Fabio; Baiocchi, Gianluca; Berti, Stefano; Besselink, Marc-G; Daradkeh, Salam; De-Carlis, Luciano; Delvecchio, Antonella; Dervenis, Christos; Dokmak, Safi; Ferrari, Clarissa; Fusai, Giuseppe-Kito; Geller, David; Goh, Brian-K-P; Guglielmi, Alfredo; Iannitti, David; Jaradat, Derar; Jovine, Elio; Kuo-Hsin, Chen; Liu, Rong; Marudanayagam, Ravi; Mocchegiani, Federico; Panaro, Fabrizio; Pinna, Antonio; Portolani, Nazario; Saleh, Omar; Sallemi, Claudio; Serrablo, Alejandro; Smadi, Sameer; Suhool, Amal; Taylor, Mark-A; van-Gulik, Thomas-M; Siriwardena, Ajith-K; Asbun, Horacio-J (OXFORD UNIV PRESS, 2025-05-31)
  • Current status of nonsurgical embryo transfer in swine 
    Gil, María-Antonia; Parrilla, Inmaculada; Cuello, Cristina; Martínez, Emilio-A (CSIRO PUBLISHING, 2025)
  • Conjugation of a cyclometalated Ir(iii) complex to human serum albumin for oncosis-mediated photodynamic therapy 
    Linero-Artiaga, Antonio; Servos, Lisa-Marie; Papadopoulos, Zisis; Rodríguez-Hernández, Venancio; Ruiz, José; Karges, Johannes (ROYAL SOC CHEMISTRY, 2025)
  • Metal-coumarin derivatives as promising photosensitizers: unlocking their cancer phototherapy potential 
    Vigueras, Gloria; Izquierdo-García, Eduardo; de-la-Torre-Rubio, Elena; Abad-Montero, Diego; Santana-Lario, María-Dolores; Marchan, Vicente; Ruiz, José (ROYAL SOC CHEMISTRY, 2025)
  • Insights into type I photoreactivity of cyclometalated iridium(iii) and ruthenium(ii) photosensitizers 
    Vigueras, Gloria; Marchan, Vicente; Ruiz, José (ROYAL SOC CHEMISTRY, 2025)
    Photodynamic therapy (PDT) is a light-activated treatment that relies on the generation of cytotoxic reactive oxygen species (ROS). While most clinically approved photosensitizers (PSs) operate through a type II mechanism-based ...

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