Repositorio Dspace

Envíos recientes

03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla): Envíos recientes

  • Microbial bile salt hydrolase activity influences gene expression profiles and gastrointestinal maturation in infant mice 
    Nunez-Sánchez, María-A; Herisson, Florence-M; Keane, Jonathan-M; García-González, Natalia; Rossini, Valerio; Pinhiero, Jorge; Daly, Jack; Bustamante-Garrido, Milan; Hueston, Cara-M; Patel, Shriram; Canela, Nuria; Herrero, Pol; Claesson, Marcus-J; Melgar, Silvia; Nally, Ken; Caplice, Noel-M; Gahan, Cormac-GM (TAYLOR & FRANCIS INC, 2022-12-31)
    The mechanisms by which early microbial colonizers of the neonate influence gut development are poorly understood. Bacterial bile salt hydrolase (BSH) acts as a putative colonization factor that influences bile acid ...
  • The impact of resilience as a protective factor on Health-Related Quality of Life's psychological dimensions among adolescents who experience peer victimization 
    de-Lourdes-Martín-Pérez, Angela; Moran-Sánchez, Ines; José-Gascon-Canovas, Juan (NATURE PORTFOLIO, 2022-11)
    Peer victimization have a negative impact on Health-Related Quality of Life (HRQoL) during adolescence, however some personal skills such a person's resilience could play a significant role in this relationship. In this ...
  • Zebrafish models of COVID-19 
    Tyrkalska, Sylwia-D; Candel, Sergio; Pedoto, Annamaria; García-Moreno, Diana; Alcaraz-Pérez, Francisca; Sánchez-Ferrer, Alvaro; Cayuela, María-L; Mulero, Victoriano (OXFORD UNIV PRESS, 2023-01-16)
    Although COVID-19 has only recently appeared, research studies have already developed and implemented many animal models for deciphering the secrets of the disease and provided insights into the biology of SARS-CoV-2. ...
  • Enforced mesenchymal stem cell tissue colonization counteracts immunopathology 
    García-Bernal, David; Blanquer, Miguel; Martínez, Carlos-M; García-Guillen, Ana, I; García-Hernández, Ana-M; Carmen-Alguero, M; Yanez, Rosa; Lamana, María-L; Moraleda-Jiménez, José-María; Sackstein, Robert (NATURE PORTFOLIO, 2022-10)
    Mesenchymal stem/stromal cells (MSCs) are distributed within all tissues of the body. Though best known for generating connective tissue and bone, these cells also display immunoregulatory properties. A greater understanding ...
  • P2X7 receptor activation impairs antitumour activity of natural killer cells 
    Baroja-Mazo, Alberto; Penin-Franch, Alejandro; Lucas-Ruiz, Fernando; De-Torre-Minguela, Carlos; Alarcon-Vila, Cristina; Hernández-Caselles, Trinidad; Pelegrín, Pablo (WILEY, 2023-01)
    BACKGROUND AND PURPOSE: A high number of intratumoural infiltrating natural killer (NK) cells is associated with better survival in several types of cancer, constituting an important first line of defence against tumours. ...
  • Smoking remains associated with education after controlling for social background and genetic factors in a study of 18 twin cohorts 
    Silventoinen, Karri; Piirtola, Maarit; Jelenkovic, Aline; Sund, Reijo; Tarnoki, Adam-D; Tarnoki, David-L; Medda, Emanuela; Nistico, Lorenza; Toccaceli, Virgilia; Honda, Chika; Inui, Fujio; Tomizawa, Rie; Watanabe, Mikio; Sakai, Norio; Gatz, Margaret; Butler, David-A; Lee, Jooyeon; Lee, Soo-Ji; Sung, Joohon; Franz, Carol-E; Kremen, William-S; Lyons, Michael-J; Derom, Catherine-A; Vlietinck, Robert-F; Loos, Ruth-JF; Tynelius, Per; Rasmussen, Finn; Martín, Nicholas-G; Medland, Sarah-E; Montgomery, Grant-W; Brandt, Ingunn; Nilsen, Thomas-S; Harris, Jennifer-R; Tyler, Jessica; Hopper, John-L; Magnusson, Patrik-KE; Pedersen, Nancy-L; Aslan, Anna-KDahl; Ordonana, Juan-R; Sánchez-Romera, Juan-F; Colodro-Conde, Lucia; Rebato, Esther; Zhang, Dongfeng; Pang, Zengchang; Tan, Qihua; Silberg, Judy-L; Maes, Hermine-H; Boomsma, Dorret, I; Sorensen, Thorkild-IA; Korhonen, Tellervo; Kaprio, Jaakko (NATURE PORTFOLIO, 2022-07)
    We tested the causality between education and smoking using the natural experiment of discordant twin pairs allowing to optimally control for background genetic and childhood social factors. Data from 18 cohorts including ...
  • Oleanolic acid stimulation of cell migration involves a biphasic signaling mechanism 
    Stelling-Ferez, Javier; Antonio-Gabaldon, José; José-Nicolas, Francisco (NATURE PORTFOLIO, 2022-09)
    Cell migration is a critical process for wound healing, a physiological phenomenon needed for proper skin restoration after injury. Wound healing can be compromised under pathological conditions. Natural bioactive terpenoids ...
  • Detection of kinase domain mutations in BCR::ABL1 leukemia by ultra-deep sequencing of genomic DNA 
    Sánchez, Ricardo; Dorado, Sara; Ruiz-Heredia, Yanira; Martín-Munoz, Alejandro; Manuel-Rosa-Rosa, Juan; Ribera, Jordi; García, Olga; Jiménez-Ubieto, Ana; Carreno-Tarragona, Gonzalo; Linares, María; Rufian, Laura; Juárez, Alexandra; Carrillo, Jaime; José-Espino, María; Caceres, Mercedes; Exposito, Sara; Cuevas, Beatriz; Vanegas, Raul; Felipe-Casado, Luis; Torrent, Anna; Zamora, Lurdes; Mercadal, Santiago; Coll, Rosa; Cervera, Marta; Morgades, Mireia; Angel-Hernández-Rivas, José; Bravo, Pilar; Seri, Cristina; Anguita, Eduardo; Barragan, Eva; Sargas, Claudia; Ferrer-Marín, Francisca; Sánchez-Calero, Jorge; Sevilla, Julián; Ruiz, Elena; Villalon, Lucia; del-Mar-Herraez, María; Riaza, Rosalia; Magro, Elena; Luis-Steegman, Juan; Wang, Chongwu; de-Toledo, Paula; García-Gutierrez, Valentin; Ayala, Rosa; Ribera, Josep-María; Barrio, Santiago; Martínez-López, Joaquin (NATURE PORTFOLIO, 2022-07)
    The screening of the BCR::ABL1 kinase domain (KD) mutation has become a routine analysis in case of warning/failure for chronic myeloid leukemia (CML) and B-cell precursor acute lymphoblastic leukemia (ALL) Philadelphia ...
  • Dystonia genes functionally converge in specific neurons and share neurobiology with psychiatric disorders 
    Mencacci, Niccolo-E; Reynolds, Regina; Ruiz, Sonia-García; Vandrovcova, Jana; Forabosco, Paola; Sánchez-Ferrer, Alvaro; Volpato, Viola; Weale, Michael-E; Bhatia, Kailash-P; Webber, Caleb; Hardy, John; Botia, Juan-A; Ryten, Mina (OXFORD UNIV PRESS, 2020-09)
    Dystonia is a neurological disorder characterized by sustained or intermittent muscle contractions causing abnormal movements and postures, often occurring in absence of any structural brain abnormality. Psychiatric ...
  • Case report of Tourniquet ALPPS and simultaneous sleeve gastrectomy A valuable association to achieve an adequate future liver remnant in obese patients 
    Brusadin, Roberto; López-López, Victor; Ruiz-de-Angulo, David; López-Conesa, Asuncion; Navarro-Barrios, Alvaro; Caballero-Planes, Albert; Parrilla-Paricio, Pascual; Robles-Campos, Ricardo (LIPPINCOTT WILLIAMS & WILKINS, 2020-08-21)
    INTRODUCTION: Obesity represents a risk factor in case of major hepatectomy, because the future liver remnant (FLR) must be proportional with body weight. To avoid post-hepatectomy liver failure, and further increase the ...
  • Mediating effect of soluble B-cell activation immune markers on the association between anthropometric and lifestyle factors and lymphoma development 
    Hosnijeh, Fatemeh-Saberi; Kolijn, Pieter-M; Casabonne, Delphine; Nieters, Alexandra; Solans, Marta; Naudin, Sabine; Ferrari, Pietro; Mckay, James-D; Weiderpass, Elisabete; Perduca, Vittorio; Besson, Caroline; Mancini, Francesca-Romana; Masala, Giovanna; Krogh, Vittorio; Ricceri, Fulvio; Huerta-Castaño, José-María; Petrova, Dafina; Sala, Nuria; Trichopoulou, Antonia; Karakatsani, Anna; La-Vecchia, Carlo; Kaaks, Rudolf; Canzian, Federico; Aune, Dagfinn; Boeing, Heiner; Schulze, Matthias-B; Pérez-Cornago, Aurora; Langerak, Anton-W; van-der-Velden, Vincent-HJ; Vermeulen, Roel (NATURE PORTFOLIO, 2020-08-14)
    Sustained B-cell activation is an important mechanism contributing to B-cell lymphoma (BCL). We aimed to validate four previously reported B-cell activation markers predictive of BCL risk (sCD23, sCD27, sCD30, and CXCL13) ...
  • Effectiveness of individualized inhaler technique training on low adherence (LowAd) in ambulatory patients with COPD and asthma 
    Miguel-Sánchez-Nieto, Juan; Bernabeu-Mora, Roberto; Fernández-Munoz, Irene; Carrillo-Alcaraz, Andres; Alcantara-Fructuoso, Juan; Fernández-Alvarez, Javier; Carlos-Vera-Olmos, Juan; José-Martínez-Ferre, María; Garci-Varela-Olea, Mercedes; Corcoles-Valenciano, María-José; Salmerón-Martínez, Diego (NATURE PORTFOLIO, 2022-01-10)
    To analyze whether there is improvement in adherence to inhaled treatment in patients with COPD and asthma after an educational intervention based on the teach-to-goal method. This is a prospective, non-randomized, ...
  • Incidence of myeloid neoplasms in Spain (2002-2013): a population-based study of the Spanish network of cancer registries 
    Solans, Marta; Sanvisens, Arantza; Ameijide, Alberto; Merino, Susana; Rojas, Dolores; Aleman, Araceli; Banqueri, Emilia; Chico, Matilde; Marcos, Ana-Isabel; de-Castro, Visitacion; Gil, Leire; de-Munain, Arantza-López; Puigdemont, Montse; Sánchez, María-José; Perucha, Josefina; Ruiz-Armengol, Patricia; Chirlaque-López, María-Dolores; Guevara, Marcela; Carulla, María; Marcos-Gragera, Rafael (NATURE PORTFOLIO, 2022-01-10)
    Comprehensive population-based data on myeloid neoplasms (MNs) are limited, mainly because some subtypes were not recognized as hematological cancers prior to the WHO publication in 2001, and others are too rare to allow ...
  • Linezolid for infective endocarditis A structured approach based on a national database experience 
    Munoz, P; De-la-Villa, S; Martínez-Selles, M; Goenaga, MA; Reviejo-Jaka, K; Arnaiz-de-las-Revillas, F; García-Cuello, L; Hidalgo-Tenorio, C; Rodríguez-Esteban, MA; Antorrena, I; Castelo-Corral, L; García-Vazquez, E; De-la-Torre, J; Bouza, E (LIPPINCOTT WILLIAMS & WILKINS, 2021-12-23)
    Current data on the frequency and efficacy of linezolid (LNZ) in infective endocarditis (IE) are based on small retrospective series. We used a national database to evaluate the effectiveness of LNZ in IE.This is a ...
  • Clinical evaluation of antiseptic mouth rinses to reduce salivary load of SARS-CoV-2 
    Ferrer, María-D; Sánchez-Barrueco, Alvaro; Martínez-Beneyto, Yolanda; Mateos-Moreno, María, V; Ausina-Marquez, Verónica; García-Vazquez, Elisa; Puche-Torres, Miguel; Forner-Giner, María-J; Campos-González, Alfonso; Santillan-Coello, Jessica-M; Alcala-Rueda, Ignacio; Villacampa-Auba, José-M; Cenjor-Espanol, Carlos; López-Velasco, Ana; Santolaya-Abad, Diego; García-Esteban, Sandra; Artacho, Alejandro; López-Labrador, Xavier; Mira, Alex (NATURE PORTFOLIO, 2021-12-22)
    Most public health measures to contain the COVID-19 pandemic are based on preventing the pathogen spread, and the use of oral antiseptics has been proposed as a strategy to reduce transmission risk. The aim of this manuscript ...
  • Nitric oxide-targeted protein phosphorylation during human sperm capacitation 
    Staicu, Florentin-Daniel; Carlos-Martínez-Soto, Juan; Canovas, Sebastian; Matas, Carmen (NATURE PORTFOLIO, 2021-10)
    Among many other molecules, nitric oxide insures the correct progress of sperm capacitation by mediating phosphorylation events. For a more comprehensive understanding of how this happens, we capacitated human spermatozoa ...
  • Granulocyte-macrophage colony stimulating factor (GM-CSF) is fully expressed in the genital tract, seminal plasma and spermatozoa of male pigs 
    Padilla, Lorena; Martínez-Hernández, Jesus; Barranco, Isabel; Lucas, Xiomara; Pastor, Luis-M; Rodríguez-Martínez, Heriberto; Roca, Jordi; Parrilla, Inmaculada (NATURE PORTFOLIO, 2020-08-07)
    Granulocyte-macrophage colony stimulating factor (GM-CSF) is a pro-inflammatory cytokine identified in boar seminal plasma (SP) but until now unexplored in terms of place of production and its association to spermatozoa. ...
  • Cardiac tyrosine hydroxylase activation and MB-COMT in dyskinetic monkeys 
    Cuenca-Bermejo, Lorena; Almela, Pilar; Gallo-Soljancic, Pablo; Yuste, José-E; de-Pablos, Vicente; Bautista-Hernández, Victor; Fernández-Villalba, Emiliano; Laorden, María-Luisa; Herrero, María-Trinidad (NATURE PORTFOLIO, 2021-10)
    The impact of age-associated disorders is increasing as the life expectancy of the population increments. Cardiovascular diseases and neurodegenerative disorders, such as Parkinson's disease, have the highest social and ...
  • Low-affinity immunoglobulin gamma Fc region receptor III-B (Fc?RIIIB, CD16B) deficiency in patients with blood and immune system disorders 
    Minguela-Puras, Alfredo; Salido, Eduardo-J; Soto-Ramirez, María-F; Olga, Montes-Ares; Leal, Juan-D; García-Garay, María-C; Periago, Adela; Berenguer, Mercedes; Blanque, Miguel; Campillo, José-A (WILEY, 2021-12)
    Low-affinity immunoglobulin gamma Fc region receptor III-B (Fc?RIIIB) deficiency is present in ?0·05% of the general population. Among our patients, Fc?RIIIB deficiency was less frequent in those with immune-system disorders ...
  • Prognostic biomarkers of Parkinson's disease in the Spanish EPIC cohort: a multiplatform metabolomics approach 
    González-Riano, Carolina; Saiz, Jorge; Barbas, Coral; Bergareche, Alberto; Huerta-Castaño, José-María; Ardanaz, Eva; Konjevod, Marcela; Mondragon, Elisabet; Erro, ME; Chirlaque-López, María-Dolores; Abilleira, Eunate; Goni-Irigoyen, Fernando; Amiano, Pilar (NATURE PORTFOLIO, 2021-08-16)
    The lack of knowledge about the onset and progression of Parkinson's disease (PD) hampers its early diagnosis and treatment. Metabolomics might shed light on the PD imprint seeking a broader view of the biochemical remodeling ...

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