Repositorio Dspace

Envíos recientes

03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla): Envíos recientes

  • Long-term liver stiffness dynamics after sustained virological response in patients with HIV/HCV co-infection and advanced fibrosis 
    Martín-Carmona, Jesica; Corona-Mata, Diana; Tellez, Francisco; Navarrete-Lorite, Miguel-Nicolás; Barroso, Isabel; Alados, Juan-Carlos; Palacios-Muñoz, Rosario; de-los-Santos, Ignacio; Vera-Méndez, Francisco-Jesús; Imaz, Arkaitz; Raffo-Marquez, Miguel; Morano-Vazquez, Aitana-Carla; Galindo, María-José; Belinchon, Olga; Serrano-Fuentes, Miriam; López-Zuniga, Miguel-Ángel; Galera-Peñaranda, Carlos; Reus-Banuls, Sergio-Javier; Pineda, Juan-A; Macias, Juan; Corma-Gómez, Anais (LIPPINCOTT WILLIAMS & WILKINS, 2026-02)
    Objective: This study analyses liver stiffness (LS) dynamics in people with HIV (PWH) and advanced liver fibrosis who achieved sustained virological response (SVR) and assess factors associated with LS normalization or ...
  • Graph Alignment Methods for the Development of Interoperable Gene Regulation Knowledge Graphs 
    Mulero-Hernández, Juan; Almagro-Hernández, Ginés; Fernández-Breis, Jesualdo-Tomás (IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC, 2026)
    Biological and biomedical knowledge graphs can be disparate in their design when a standard has not been widely accepted by the community, even more when they represent data from a previously underexplored domain. This may ...
  • Initial Experience With Del Nido Cardioplegia in Adult Cardiac Transplantation. 
    Aranda-Domene, Ramón; Blanco-Morillo, Juan; Alcaraz-García, María-José; Arribas-Leal, José-María; Gutiérrez-García, Francisco; García-Puente-del-Corral, Julio; Garrido-Bravo, Iris-Paula; Pastor-Pérez, Francisco-José; Jara-Rubio, Rubén; Royo-Villanova, Mario; García-Candel, Antonio; Alfonso-Colomer, Laura; Moreno-Moreno, José-Antonio; Cánovas-López, Sergio (LIPPINCOTT WILLIAMS & WILKINS, 2026-01-05)
    Del Nido Cardioplegia (DNC) is widely used in nontransplant cardiac surgery, but its role as a preservation solution in cardiac transplantation is unclear. We conducted a retrospective observational study of 61 patients ...
  • Circadian alterations in isolated Rapid-Eye-Movement sleep behavior disorder: associations with clinical, glymphatic, and dopaminergic imaging markers 
    Roura, Ignacio; Pardo, Jessica; Martín-Barceló, Cristina; Pacheco-Jaime, Laura; García-Vicente, Carla; Falcon, Carles; Madrid, Juan-Antonio; Rol, María-Ángeles; Ninerola-Baizan, Aida; Perissinotti, Andrés; Sala-Llonch, Roser; Bargallo, Nuria; Serradell, Mónica; Pont-Sunyer, Claustre; Gaig, Carles; Maya, Gerard; Montini, Ángelica; Adan, Ana; Junque, Carme; Iranzo, Alex; Segura, Bárbara (OXFORD UNIV PRESS INC, 2026-01-06)
    Alterations in sleep-wake patterns are well-recognized features of overt alpha-synucleinopathies. However, their presence in prodromal stages, characterized by isolated Rapid-Eye-Movement (REM) sleep behavior disorder, ...
  • Development of a blood-based lipidomic fat quality score for the risk of ischemic stroke 
    Lazaro, Iolanda; Lujan-Barroso, Leila; Soldevila-Domenech, Natalia; Amor, Antonio-J; Ortega, Emilio; Ros, Emilio; Sánchez, María-José; Rodríguez-Barranco, Miguel; Guevara, Marcela; Moreno-Iribas, Conchi; Schroder, Helmut; Fito, Montserrat; Tintle, Nathan-L; Ryder, Nathan; Harris, William-S; Agudo, Antonio; Sala-Vila, Aleix (SAGE PUBLICATIONS LTD, 2026-01-01)
    Introduction: Poor-quality diets promote ischemic stroke. Red blood cell fatty acids (RBC-FAs) are objective, longterm biomarkers of diet. In a case-control study nested in the European Prospective Investigation into Cancer ...
  • Effect of beta blockers in acute and chronic coronary syndromes without reduced ejection fraction: a landmark analysis from the REBOOT trial. 
    Rossello, Xavier; Barrabes, José-A; Piepoli, Massimo; Dominguez-Rodríguez, Alberto; Sánchez, Pedro-L; Anguita, Manuel; Raposeiras-Roubin, Sergio; Grigis, Giulietta; Aguero, Jaume; Owen, Ruth; Pocock, Stuart; Pérez-García, Carlos-Nicolás; Escalera, Noemi; Kallmeyer, Andrea; Sionis, Alessandro; Staszewsky, Lidia; Torres, Alfonso; Barquero, Rocio; Fernández-Vazquez, Felipe; Marín-Ortuño, Francisco; Vetrano, Alfredo; Pastor, Pablo; Fuster, Valentín; Latini, Roberto; Ibañez, Borja (2026-01-22)
    BACKGROUND AND AIMS: Current guidelines recommend beta-blocker therapy after myocardial infarction (MI) regardless of left ventricular ejection fraction (LVEF). However, recent trials question their benefit in patients ...
  • Metabolomic profiling of urinary phenolic compounds in postmenopausal women after consumption of dark chocolate, green tea, and fruit juice 
    Sánchez-Martínez, Lorena; Tosi, Nicole; Bragazzi, Nicola-Luigi; Bresciani, Letizia; del-Rio, Daniele; Periago, María-Jesús; Mena, Pedro; González-Barrio, Rocío (ROYAL SOC CHEMISTRY, 2026)
    Postmenopausal women are approximately twice as likely to develop cardiometabolic diseases (CMDs) as premenopausal women. Plant-based diets rich in fruits and vegetables, due to their high content of bioactive compounds ...
  • TKI-mediated inhibition of NLRP1 inflammasome restores erythropoiesis in DBA syndrome 
    Lozano-Gil, Juan-Manuel; Rodríguez-Ruiz, Lola; Palacios, Manuel; Peral, Jorge; Navarro, Susana; Fuster-Soler, José-Luis; Beléndez, Cristina; Jérez-Cayuela, Andrés; Murillo-Sanjuan, Laura; Díaz-de-Heredia, Cristina; López-de-Hontanar, Guzmán; Zubicaray, Josune; Sevilla, Julián; Ferrer-Marín, Francisca; Sepulcre-Cortés, María-Pilar; Cayuela-Fuentes, María-Luisa; García-Moreno, Diana; Martínez-López, Alicia; Tyrkalska, Sylwia-D; Mulero, Victoriano (SPRINGERNATURE, 2026-01-09)
    Diamond-Blackfan anemia syndrome (DBAS) is marked by defective erythropoiesis caused by impaired ribosome biogenesis and aberrant signaling. Here, we investigate how ribosomal stress-induced activation of the NLRP1 ...
  • Expanding the genetic landscape of inherited metabolic diseases using long-read sequencing and transcriptomic profiling 
    Soriano-Sexto, Alejandro; Sánchez-Lijarcio, Obdulia; Beccari, Leonardo; Castejón-Fernández, Natalia; Leal, Fátima; Alcaide, Patricia; de-la-Morena-Barrio, Belén; Bahillo-Curieses, María-del-Pilar; Correcher, Patricia; Hencke-Tresbach, Rafael; López, Laura; Martín-Hernández, Elena; Yahyaoui, Raquel; Ugarte, Magdalena; Rodríguez-Pombo, Pilar; Pérez, Belén (SPRINGERNATURE, 2026-01-26)
    Although next-generation sequencing has emerged as a powerful tool for diagnosing rare diseases (RD), many cases of inherited metabolic diseases (IMD) remain unsolved, hindering the diagnosis, clinical and therapeutic ...
  • One-year consolidation with Ponatinib 15 mg in chronic myeloid leukaemia on deep molecular response with Imatinib 
    Pérez-Lamas, Lucía; Manzanares, Mario; Hernández-Boluda, Juan-Carlos; Casado-Montero, Luis-Felipe; Gómez-Casares, María-Teresa; Ayala, Rosa; Xicoy, Blanca; Ferrer-Marín, Francisca; Orti, Guillermo; De-Paz-Arias, Raquel; Osorio-Prendes, Santiago; Pérez-López, Raúl; Mora, Elvira; Ruiz-Nuno, Concepción; Jiménez-Velasco, Antonio; Boque, Concepción; Sierra-Pacho, Magdalena; Martínez-López, Joaquín; Carreño-Tarragona, Gonzalo; Coiras, Mayte; García-Gutiérrez, Valentín (SPRINGERNATURE, 2026-01-20)
    Tyrosine kinase inhibitors (TKIs) discontinuation is the standard option for patients with chronic myeloid leukaemia (CML) in deep molecular response (MR) with imatinib. This study aimed to evaluate the efficacy and safety ...
  • Roots of resilience: Assessing child and adolescent nature connectivity in the Mediterranean Region of Murcia (Spain) 
    Ortega-García, Juan-Antonio; Díaz-Martínez, Francisco; Cabrera-Rivera, Laura-Teresa; Cánovas-Conesa, Carmen-Alicia; Codina, Elena; Ramis, Rebeca; Claudio, Luz (WILEY, 2026-02)
    <p style="border:0px; display:block; height:0px; left:-9999px; margin-bottom:0px; margin-left:0px; margin-right:0px; margin-top:0px; opacity:0; overflow:hidden; padding:0px; position:absolute; top:0px; width:0px"> Children ...
  • Differences in circadian sleep parameters as a function of gender in patients on the waiting list for liver transplantation. 
    Martínez-Alarcon, Laura; Jover-Águilar, Marta; Sáez-Sánchez, Javier; Ramírez, Pablo; Ramis-Vidal, Guillermo (ELSEVIER, 2026-02)
    Sleep is a critical component of health, yet its role is underexplored in patients awaiting organ transplantation. This study examined sex-based differences in circadian sleep indicators among liver transplant candidates. ...
  • Healthcare resource utilization and costs of chronic kidney disease in Spain across KDIGO categories: Insights from real-world evidence 
    Santamaría, Rafael; Escobar, Carlos; Aranda, Unai; Palacios, Beatriz; Capel, Margarita; Hernández, Ignacio; Cebrián-Cuenca, Ana-María; Alcázar, Roberto; Gorostidi, Manuel (ELSEVIER, 2026-01)
    Aim: To determine the healthcare resource utilization and costs in patients with chronic kidney disease (CKD) across the KDIGO stages in real-world clinical practice in Spain. Methods: Observational, retrospective study ...
  • Chaperone-mediated autophagy sustains pericyte stemness necessary for brain tissue homeostasis 
    Salinas, María-Dolores; Martínez, Carlos-M; Roca, Francisco-J; García-Bernal, David; Martínez-Morga, Marta; Rodríguez-Madoz, Juan-R; Prosper, Felipe; Zapata, Agustin-G; Moraleda-Jiménez, José-María; Martínez, Salvador; Valdor-Alonso, Rut (ELSEVIER, 2026-02)
    Introduction: Pericytes (PCs) are mural cells exhibiting some mesenchymal stem cell (MSC) properties and contribute to tissue regeneration after injury. We have previously shown that glioblastoma cancer cells induce in ...
  • Scoping review of the evolution of delirium detection, diagnostic, and severity assessment scales 
    Alonso-Crespo, David; Rodríguez-Mondéjar, Juan-José; Leal-Costa, César (ELSEVIER, 2026-04)
    Aim/Objective: To systematically compile and analyze all delirium detection tools, establishing a temporal and contextual framework to clarify current knowledge. Background: Delirium is a prevalent condition in hospitalized ...
  • Neuroimmune regulation of inflammation: RNA-Seq study of somatostatin-6 effects in gilthead seabream (Sparus aurata) skin and brain 
    Campos-Sánchez, José-Carlos; Espinosa-Ruiz, Cristobal; Marín-Parra, Claudia; Guardiola, Francisco-A; Rubio, Teresa; Pérez-Sanz, Fernando; Esteban, María-Ángeles (ELSEVIER, 2026-03)
    This study evaluated the anti-inflammatory potential of gilthead seabream somatostatin-6 (SST6) in a 2-carra-geenan-induced inflammation model using RNA-seq transcriptomics. We compared gene expression in the skin (primary ...
  • Traffic-related air pollution in utero modifies cytokine responses to stimuli of umbilical cord blood cells: a cohort study 
    García-Serna, Azahara-María; Martín-Orozco, Elena; Jiménez-Guerrero, Pedro; Hernández-Caselles, Trinidad; Cantero-Cano, Esther; Elena, María-del-Carmen; Soler-Sánchez, Jesús; García-Marcos, Luis; Morales, Eva (ELSEVIER, 2026-03)
    Objective: To examine the associations between in utero exposure to traffic-related air pollutants (TRAP) and cytokine responses to stimuli in newborns. Methods: Luminex technology was used to assess cytokine responses in ...
  • Genome-wide interaction analysis of long-term trihalomethane exposure in drinking water and colorectal cancer risk in a Spanish Multicenter Case-Control Study (MCC-Spain) 
    Moratalla-Navarro, Ferrán; Obon-Santacana, Mireia; Rius-Sansalvador, Blanca; Guino, Elisabet; Moragas, Nuria; Donat-Vargas, Carolina; Fernández-de-Larrea-Baz, Nerea; Molina-Barcelo, Ana; Guevara, Marcela; Morón-Durán, Francisco-D; Dierssen-Sotos, Trinidad; Tardon, Adonina; Castaño-Vinyals, Gemma; Cabrera-Castro, Natalia; Molina, Antonio-José; Aizpurua, Amaia; Morales-Suarez-Varela, María-M; Martín, Vicente; Fernández-Navarro, Pablo; Villanueva, Cristina-M; Moreno, Victor (ELSEVIER, 2026-01)
    We conducted a genome-wide interaction analysis between long-term exposure to trihalomethanes in drinking water and colorectal cancer (CRC) risk in a multicenter case-control study in Spain, including 1037 CRC cases and ...
  • Ultrastructural and immunobiological responses of human periodontal ligament stem cells to novel tricalcium silicate sealers 
    Pérez-Guzman, Nuria; García-Ríos, Paula; Rodríguez-Lozano, Francisco-J; García-Bernal, David; El-Yahyaoui, Ali; López-García, Sergio (ELSEVIER, 2026-02)
    Objectives This study was conducted to examine the biocompatibility, regenerative potential, and immunomodulatory effects of three formulated calcium silicate-containing sealers (CSCS)-TotalFill BC Sealer (TFbc), NeoSEALER ...
  • A comprehensive view of software vulnerability risks through enterprise knowledge graphs 
    Egana-Aranguren, Mikel; Fernández-Breis, Jesualdo-Tomás; Leon-Balentzia, Bidane; Rompe, Markus; García-Castro, Alexander (ELSEVIER, 2026-04)
    Cybersecurity has emerged as a critical concern for modern enterprises due to the increasing complexity and diversity of threats. These risks exploit multiple attack vectors, such as phishing, unpatched vulnerabilities, ...

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