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Envíos recientes

03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla): Envíos recientes

  • Nurses' sleep quality, work environment and quality of care in the Spanish National Health System: observational study among different shifts 
    Gomez-García, Teresa; Moreno-Casbas, Teresa; Ruzafa-Martínez, María; Fuentelsaz-Gallego, Carmen; Madrid, Juan-Antonio; Rol, María-Ángeles; Martínez-Madrid, María-José (2016-08)
    OBJECTIVE: The main objective of this study was to determine the relationship between the characteristics of nurses' work environments in hospitals in the Spanish National Health System (SNHS) with nurse reported quality ...
  • Usefulness of percutaneous elastography by acoustic radiation force impulse for the non-invasive diagnosis of chronic pancreatitis 
    Llamoza-Torres, Camilo-Julio; Fuentes-Pardo, María; Álvarez-Higueras, Francisco-Javier; Alberca-de-las-Parras, Fernando; Carballo-Álvarez, Luis-Fernando (2016)
    OBJECTIVE: To determine the accuracy of the acoustic radiation force impulse (ARFI) technique for the diagnosis of chronic pancreatitis. MATERIALS AND METHODS: We present an observational, single-center study that included ...
  • Post-traumatic stress disorder associated with life-threatening motor vehicle collisions in the WHO World Mental Health Surveys 
    Stein, Dan-J; Karam, Elie-G; Shahly, Victoria; Hill, Eric-D; King, Andrew; Petukhova, María; Zaslavsky, Alan-M; Kessler, Ronald-C; Atwoli, Lukoye; Bromet, Evelyn-J; Florescu, Silvia; María-Haro, Josep; Hinkov, Hristo; Karam, Aimee; Elena-Medina-Mora, María; Navarro-Mateu, Fernando; Piazza, Marina; Shalev, Arieh; Torres, Yolanda (2016-12)
    BACKGROUND: Motor vehicle collisions (MVCs) are a substantial contributor to the global burden of disease and lead to subsequent post-traumatic stress disorder (PTSD). However, the relevant literature originates in only a ...
  • The oviductal transcriptome is influenced by a local ovarian effect in the sow 
    López-Ubeda, Rebeca; Vieira, Luis; Munoz, Marta; Hunter, Ronald-H-F; Coy-Fuster, Pilar; Cánovas, Sebastián (2016-12)
    BACKGROUND: Oviducts participate in fertilization and early embryo development, and they are influenced by systemic and local circulation. Local functional interplay between ovary, oviduct and uterus is important, as deduced ...
  • Association of Plasma Phospholipid n-3 and n-6 Polyunsaturated Fatty Acids with Type 2 Diabetes: The EPIC-InterAct Case-Cohort Study 
    Forouhi, Nita-G; Imamura, Fumiaki; Sharp, Stephen-J; Zheng, Jusheng; Ye, Zheng; Langenberg, Claudia; Wareham, Nicholas-J; Koulman, Albert; Wang, Laura-Yun; Summerhill, Keith; Griffin, Julian-L; Schulze, Matthias-B; Kroeger, Janine; Sluijs, Ivonne; van-der-Schouw, Yvonne-T; Guevara, Marcela; Huerta-Castaño, José-María; Feskens, Edith-J-M; Affret, Aurelie; Dow, Courtney; Fagherazzi, Guy; Amiano, Pilar; Boeing, Heiner; Nilsson, Peter-M; Franks, Paul-W; Rolandsson, Olov; González, Carlos; Kaaks, Rudolf; Kuehn, Tilman; Key, Timothy-J; Khaw, Kay-Tee; Mortensen, Lotte-Maxild; Overvad, Kim; Pala, Valeria; Palli, Domenico; Panico, Salvatore; Ramon-Quiros, J; Rodriguez-Barranco, Miguel; Sacerdote, Carlotta; Scalbert, Augustin; Slimani, Nadia; Spijkerman, Annemieke-M-W; van-der-A, Daphne-L; Tjonneland, Anne; Tormo-Díaz, María-José; Tumino, Rosario; Riboli, Elio (2016-07-19)
    BACKGROUND: Whether and how n-3 and n-6 polyunsaturated fatty acids (PUFAs) are related to type 2 diabetes (T2D) is debated. Objectively measured plasma PUFAs can help to clarify these associations. METHODS AND FINDINGS: ...
  • Acceptance of living liver donation among medical students: A multicenter stratified study from Spain 
    Martínez-Alarcón, Laura; Parrilla-Paricio, Pascual; Ramírez, Pablo; Ríos-Zambudio, Antonio; López-Navas, Ana-Isabel; Isabel-López-López, Ana; Javier-Gomez, Francisco; Iriarte, Jorge; Herruzo, Rafael; Blanco, Gerardo; Javier-Llorca, Francisco; Asunsolo, Angel; Sánchez-Gallegos, Pilar; Antonio-Bondia, José; Ramon-Gutierrez, Pedro; Fernández, Ana; Teresa-de-Jesus, María; Lana, Alberto; Fuentes, Lorena; Ramon-Hernández, Juan; Virseda, Julio; Yelamos, José; Hernández, Antonio-Miguel; Ayala, Marco-Antonio (2016)
    AIM: To analyze the attitude of Spanish medical students toward living liver donation (LLD) and to establish which factors have an influence on this attitude. STUDY TYPE: A sociological, interdisciplinary, multicenter and ...
  • Natural Killer Cell Receptors and Cytotoxic Activity in Phosphomannomutase 2 Deficiency (PMM2-CDG) 
    García-López, Roberto; Hernández-Caselles, Trinidad; de-la-Morena-Barrio, María-Eugenia; Alsina, Laia; Perez-Duenas, Belen; Serrano, Mercedes; Jaeken, Jaak; Casado, Mercedes (2016-07-14)
    BACKGROUND: PMM2-CDG is the most common N-glycosylation defect and shows an increased risk of recurrent and/or severe, sometimes fatal, infections in early life. We hypothesized that natural killer (NK) cells, as important ...
  • X-ray diffraction and NMR data for the study of the location of idebenone and idebenol in model membranes. 
    Gómez-Murcia, Victoria; Torrecillas, Alejandro; deGodos, Ana-M; Corbalan-García, Senena; Gómez-Fernández, Juan-C (2016-06)
    Here we present some of our data about the interaction of idebenone and idebenol with dipalmitoyl-phosphatidylcholine (DPPC). In particular, we include data of small angle X-ray diffraction (SAXD) and wide angle X-ray ...
  • Lebein, a Snake Venom Disintegrin, Induces Apoptosis in Human Melanoma Cells 
    Zakraoui, Ons; Aloui, Zohra; Riahi-Chebbi, Ichrak; Karoui, Habib; Essafi-Benkhadir, Khadija; Hammouda, Manel-B; Montenegro, María-Fernanda; Sánchez-del-Campo, Luis; Rodríguez-López, José-Neptuno (2016-07-05)
    Melanoma, the most threatening form of skin cancer, has a very poor prognosis and is characterized by its very invasive and chemoresistant properties. Despite the recent promising news from the field of immunotherapy, there ...
  • Endometriomas and deep infiltrating endometriosis in adulthood are strongly associated with anogenital distance, a biomarker for prenatal hormonal environment 
    Mendiola-Olivares, Jaime; Sánchez-Ferrer, María-Luisa; Jiménez-Velázquez, Raquel; Cánovas-López, Laura; Hernández-Peñalver, Ana-Isabel; Corbalán-Biyang, Shiana; Carmona-Barnosi, Ana; Prieto-Sánchez, María-Teresa; Nieto-Díaz, Aníbal; Torres-Cantero, Alberto (2016-10)
    STUDY QUESTION: Is the length of the anogenital distance (AGD), a biomarker of the in-utero prenatal hormonal environment, associated with the presence of endometriomas and deep infiltrating endometriosis (DIE)? SUMMARY ...
  • Neutrophils mediate Salmonella Typhimurium clearance through the GBP4 inflammasome-dependent production of prostaglandins 
    Candel, Sergio; Angosto, Diego; Gómez-Abellán, Victoria; García-Moreno, Diana; Sepulcre, María-Pilar; Mulero, Victoriano; Tyrkalska, Sylwia-D; Martín-Sánchez, Fátima; Pelegrín, Pablo; Zapata-Pérez, Rubén; Sánchez-Ferrer, Álvaro (2016-07-01)
    Inflammasomes are cytosolic molecular platforms that alert the immune system about the presence of infection. Here we report that zebrafish guanylate-binding protein 4 (Gbp4), an IFN?-inducible GTPase protein harbouring a ...
  • TNFa Impairs Rhabdoviral Clearance by Inhibiting the Host Autophagic Antiviral Response 
    López-Muñoz, Azucena; Tyrkalska, Sylwia-D; Candel, Sergio; García-Moreno, Diana; Meseguer, José; Mulero, Victoriano; Martínez-López, Alicia; Falco, Alberto; Estepa, Amparo; Espín-Palazón, Raquel; Roca, Francisco-J (2016-06-28)
    TNF? is a pleiotropic pro-inflammatory cytokine with a key role in the activation of the immune system to fight viral infections. Despite its antiviral role, a few viruses might utilize the host produced TNF? to their ...
  • Circulating Osteopontin and Prediction of Hepatocellular Carcinoma Development in a Large European Population 
    Stepien, Magdalena; Jenab, Mazda; Duarte-Salles, Talita; Misra, Sandeep; Beretta, Laura; Plymoth, Amelie; Muller, David; Overvad, Kim; Olsen, Anja; Tjonneland, Anne; Baglietto, Laura; Severi, Gianluca; Boutron-Ruault, Marie-Christine; Turzanski-Fortner, Renee; Kaaks, Rudolf; Boeing, Heiner; Aleksandrova, Krasimira; Trichopoulou, Antonia; Lagiou, Pagona; Bamia, Christina; Pala, Valeria; Palli, Domenico; Mattiello, Amalia; Naccarati, Alessio; Gunter, Marc-J; Cross, Amanda-J; Riboli, Elio; Bueno-de-Mesquita, H-B(as); Peeters, Petra-H; Weiderpass, Elisabete; Quiros, J-Ramon; Agudo, Antonio; Sánchez-Cantalejo, Emilio; Ardanaz, Eva; Gavrila-Chervase, Diana; Werner, Marten; Hemmingsson, Oskar; Ohlsson, Bodil; Sjoberg, Klas; Wareham, Nicholas-J; Khaw, Kay-Tee; Bradbury, Kathryn-E; Hainaut, Pierre; Tumino, Rosario; Dorronsoro, Miren (2016-09-01)
    We previously identified osteopontin (OPN) as a promising marker for the early detection of hepatocellular carcinoma (HCC). In this study, we investigated the association between prediagnostic circulating OPN levels and ...
  • Generation of induced pluripotent stem cells (iPSCs) from a Bernard-Soulier syndrome patient carrying a W71R mutation in the GPIX gene 
    López-Onieva, Lourdes; Montes, Rosa; Lamolda, Mar; Romero, Tamara; Ayllon, Veronica; Ramos-Mejia, Veronica; Real, Pedro-J; Lozano-Almela, María-Luisa; Vicente, Vicente; Rivera, José (2016-05)
    We generated an induced pluripotent stem cell (iPSC) line from a Bernard-Soulier Syndrome (BSS) patient carrying the mutation p.Trp71Arg in the GPIX locus (BSS1-PBMC-iPS4F4). Peripheral blood mononuclear cells (PBMCs) were ...
  • Tissue-specific regulation of potassium homeostasis by high doses of cationic amino acids 
    del-Río-García, Jesús; López-García, Carlos; Lambertos, Ana; Cremades, Asunción; Peñafiel, Rafael (2016-12)
    The administration of l-arginine hydrochloride has been used for testing pituitary secretion in humans, and as an experimental model for induction of acute pancreatitis in rats and mice. Whereas in the first case, the ...
  • Heparanase Activates Antithrombin through the Binding to Its Heparin Binding Site 
    Bohdan, Nataliya; Espín, Salvador; Águila, Sonia; Teruel-Montoya, Raúl; Vicente, Vicente; Corral, Javier; Martínez-Martínez, Irene (2016-06-20)
    Heparanase is an endoglycosidase that participates in morphogenesis, tissue repair, heparan sulphates turnover and immune response processes. It is over-expressed in tumor cells favoring the metastasis as it penetrates the ...
  • Modifiable causes of premature death in middle-age in Western Europe: results from the EPIC cohort study 
    Muller, David-C; Johansson, Mattias; Ferrari, Pietro; Brennan, Paul; Murphy, Neil; Norat, Teresa; Gunter, Marc; Riboli, Elio; Tsilidis, Konstantinos-K; Boutron-Ruault, Marie-Christine; Clavel, Francoise; Dartois, Laureen; Li, Kuanrong; Kaaks, Rudolf; Weikert, Cornelia; Bergmann, Manuela; Boeing, Heiner; Tjonneland, Anne; Overvad, Kim; Luisa-Redondo, M; Agudo, Antonio; Molina-Portillo, Elena; Altzibar, Jone-M; Cirera-Suárez, Lluís; Ardanaz, Eva; Khaw, Kay-Tee; Wareham, Nicholas-J; Key, Timothy-J; Travis, Ruth-C; Bamia, Christina; Orfanos, Philippos; Trichopoulou, Antonia; Palli, Domenico; Pala, Valeria; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Bueno-de-Mesquita, H-Bas; Verschuren, W-M-Monique; Struijk, Ellen-A; Peeters, Petra-H; Engstrom, Gunnar; Melander, Olle; Sund, Malin; Weiderpass, Elisabete; Skeie, Guri; Lund, Eiliv (2016-12)
    BACKGROUND: Life expectancy is increasing in Europe, yet a substantial proportion of adults still die prematurely before the age of 70 years. We sought to estimate the joint and relative contributions of tobacco smoking, ...
  • Comparison of abdominal adiposity and overall obesity in relation to risk of small intestinal cancer in a European Prospective Cohort 
    Lu, Yunxia; Cross, Amanda-J; Murphy, Neil; Gunter, Marc-J; Riboli, Elio; Freisling, Heinz; Ferrari, Pietro; Travis, Ruth-C; Katzke, Verena-A; Kaaks, Rudolf; Olsson, Asa; Johansson, Ingegerd; Renstrom, Frida; Panico, Salvatore; Pala, Valeria; Palli, Domenico; Tumino, Rosario; Peeters, Petra-H; Siersema, Peter-D; Bueno-de-Mesquita, H-B; Klinaki, Eleni; Tsironis, Christos; Trichopoulou, Antonia; Agudo, Antonio; Navarro, Carmen; Sánchez, María-José; Barricarte, Aurelio; Boutron-Ruault, Marie-Christine; Fagherazzi, Guy; Racine, Antoine; Weiderpass, Elisabete (2016-07)
    BACKGROUND: The etiology of small intestinal cancer (SIC) is largely unknown, and there are very few epidemiological studies published to date. No studies have investigated abdominal adiposity in relation to SIC. METHODS: ...
  • miRNA-197 and miRNA-223 and cardiovascular death in coronary artery disease patients 
    Orenes-Piñero, Esteban; Marín, Francisco; Lip, Gregory-Y-H (2016-05)
  • Antithrombin controls tumor migration, invasion and angiogenesis by inhibition of enteropeptidase 
    Luengo-Gil, Ginés; Águila, Sonia; Bohdan, Nataliya; Antón, Ana-Isabel; Espín, Salvador; Ayala-de-la-Peña, Francisco; Vicente, Vicente; Corral, Javier; Martínez-Martínez, Irene; Inmaculada-Calvo, María; Martin-Villar, Ester; Quintanilla, Miguel (2016-06-08)
    Antithrombin is a key inhibitor of the coagulation cascade, but it may also function as an anti-inflammatory, anti-angiogenic, anti-viral and anti-apoptotic protein. Here, we report a novel function of antithrombin as a ...

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