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Envíos recientes

03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla): Envíos recientes

  • CA 15-3 prognostic biomarker in SARS-CoV-2 pneumonia 
    Ros-Lucas, José-Antonio; Pascual-Figal, Domingo-Andrés; Noguera-Velasco, José-Antonio; Hernández-Vicente, Alvaro; Cebreiros-López, Iria; Arnaldos-Carrillo, María; Martínez-Ardil, Isabel-M; García-Vazquez, Elisa; Aparicio-Vicente, Mario; Solana-Martínez, Elena; Ruiz-Martínez, Sheyla-Yolany; Fernández-Mula, Laura; Andujar-Espinosa, Ruben; Fernández-Suárez, Beatriz; Sánchez-Caro, María-Dolores; Penalver-Mellado, Carlos; Ruiz-López, Francisco-Jose (NATURE PORTFOLIO, 2022-04-25)
    The severity of lung involvement is the main prognostic factor in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Carbohydrate antigen 15-3 (CA 15-3), a marker of lung damage and fibrosis, could ...
  • Spontaneous and ART-induced large offspring syndrome: similarities and differences in DNA methylome 
    Li, Yahan; Lopes, Jordana-Sena; Fuster, Pilar-Coy; Rivera, Rocio-Melissa (TAYLOR & FRANCIS INC, 2022-11)
    Large/abnormal offspring syndrome (LOS/AOS) is a congenital overgrowth syndrome reported in ruminants produced by assisted reproduction (ART-LOS) which exhibit global disruption of the epigenome and transcriptome. LOS/AOS ...
  • Body Size at Different Ages and Risk of 6 Cancers: A Mendelian Randomization and Prospective Cohort Study 
    Mariosa, Daniela; Smith-Byrne, Karl; Richardson, Tom-G; Ferrari, Pietro; Gunter, Marc-J; Papadimitriou, Nikos; Murphy, Neil; Christakoudi, Sofia; Tsilidis, Konstantinos-K; Riboli, Elio; Muller, David; Purdue, Mark-P; Chanock, Stephen-J; Hung, Rayjean-J; Amos, Christopher, I; O'Mara, Tracy-A; Amiano, Pilar; Pasanisi, Fabrizio; Rodríguez-Barranco, Miguel; Krogh, Vittorio; Tjonneland, Anne; Halkjaer, Jytte; Pérez-Cornago, Aurora; Chirlaque-López, María-Dolores; Skeie, Guri; Rylander, Charlotta; Borch, Kristin-Benjaminsen; Aune, Dagfinn; Heath, Alicia-K; Ward, Heather-A; Schulze, Matthias; Bonet, Catalina; Weiderpass, Elisabete; Smith, George-Davey; Brennan, Paul; Johansson, Mattias (OXFORD UNIV PRESS INC, 2022-09)
    It is unclear if body weight in early life affects cancer risk independently of adult body weight. To investigate this question for 6 obesity-related cancers, we performed univariable and multivariable analyses using 1) ...
  • Do Antiangiogenics Promote Clot Instability? Data from the TESEO Prospective Registry and Caravaggio Clinical Trial 
    Carmona-Bayonas, Alberto; Verso, Melina; Sánchez-Canovas, Manuel; Rubio-Pérez, Jaime; García-de-Herreros, Marta; Martínez-del-Prado, Purificacion; Fernández-Pérez, Isaura; Quintanar-Verduguez, Teresa; Obispo-Portero, Berta; Pachon-Olmos, Vanessa; Gómez, David; Ortega, Laura; Serrano-Moyano, Marta; MBrozos, Elena; Biosca, Mercedes; Antonio-Rebollo, Maite; Teijeira-Sánchez, Lucia; Hernández-Pérez, Carolina; David-Cumplido-Buron, José; Martínez-Lago, Nieves; García-Pérez, Estefania; Munoz-Langa, José; Pérez-Segura, Pedro; Martínez-de-Castro, Eva; Jiménez-Fonseca, Paula; Agnelli, Giancarlo; Munoz, Andres (GEORG THIEME VERLAG KG, 2022-10)
    BACKGROUND: Venous thromboembolism (VTE) is a common complication in cancer patients. Much of its morbidity stems from the development of fatal pulmonary embolisms (PE). Little is known about the factors involved in clot ...
  • Position Statement on the Diagnosis, Treatment, and Response Evaluation to Systemic Therapies of Advanced Neuroendocrine Tumors, With a Special Focus on Radioligand Therapy 
    Capdevila, Jaume; Grande, Enrique; García-Carbonero, Rocio; Simo, Marc; del-Olmo-García, Ma-Isabel; Jiménez-Fonseca, Paula; Carmona-Bayonas, Alberto; Pubul, Virginia (OXFORD UNIV PRESS, 2022-04-05)
    BACKGROUND: The aim of this study was to provide a guidance for the management of neuroendocrine tumors (NETs) in clinical practice. MATERIAL AND METHODS: Nominal group and Delphi techniques were used. A steering committee ...
  • How Accurately Can We Recall the Timing of Food Intake? A Comparison of Food Times from Recall-Based Survey Questions and Daily Food Records 
    Gioia, Siena-C; Guirette, Melanie; Chen, Angela; Tucker, Chandler; Gray, Brianna-E; Vetter, Celine; Garaulet, Marta; Scheer, Frank-AJL; Saxena, Richa; Dashti, Hassan-S (OXFORD UNIV PRESS INC, 2022-02)
    BACKGROUND: There currently are no standard, low-cost, and validated methods to assess the timing of food intake. OBJECTIVES: The aim of this study was to validate simple, recall-based questions that can characterize food ...
  • Novel valproate half-sandwich rhodium and iridium conjugates to fight against multidrug-resistant Gram-positive bacteria 
    Marco, Alicia; Vigueras, Gloria; Busto, Natalia; Cutillas, Natalia; Bautista, Delia; Ruiz, José (ROYAL SOC CHEMISTRY, 2023-10)
    New valproate Ir(III) and Rh(III) half-sandwich conjugates containing a C,N-phenylbenzimidazole chelated ligand have been synthesized and characterized. The valproic acid conjugation to organometallic fragments seems to ...
  • Antithrombin Deficiency Is Associated with Prothrombotic Plasma Fibrin Clot Phenotype 
    Natorska, Joanna; Corral, Javier; de-la-Morena-Barrio, María-Eugenia; Bravo-Pérez, Carlos; Bagoly, Zsuzsa; Bereczky, Zsuzsanna; Trelinski, Jacek; Witkowski, Michal; Klajmon, Adrianna; Undas, Anetta; Zabczyk, Michal (GEORG THIEME VERLAG KG, 2023-09)
    BACKGROUND: Deficiency of antithrombin increases risk of venous thromboembolism. We hypothesized that antithrombin deficiency affects fibrin clot structure and function. METHODS: We evaluated 148 patients (age: 38 [32-50] ...
  • Expert Consideration on Regulatory Aspects for Perinatal Derivatives in Clinical Settings 
    Hofmann, Nicola; Lafarge, Xavier; Antica, Maríastefania; Ferry, Nicolas; Girandon, Lenart; Gramignoli, Roberto; Jurga, Marcin; Kerdjoudj, Halima; Navakauskiene, Ruta; Schiavi, Jessica; Shablii, Volodymyr; Nicolas, Francisco-J; Gindraux, Florelle (OXFORD UNIV PRESS, 2023-05)
    Perinatal derivatives (PnD) are drawing growing interest among the scientific community as an unrestricted source of multipotent stem cells, secretome, and biological matrices. They are useful for the treatment of diseases ...
  • Usefulness of PIVKA-II for monitoring after liver transplantation in patients with hepatocellular carcinoma 
    Villalba-López, Francisco; Saenz-Mateos, Luis-Francisco; Sánchez-Lorencio, María-Isabel; De-La-Orden-García, Virginia; Alconchel-Gago, Felipe; Cascales-Campos, Pedro-Antonio; García-Bernardo, Carmen; Noguera-Velasco, José-Antonio; Baroja-Mazo, Alberto; Ramírez-Romero, Pablo (NATURE PORTFOLIO, 2023-04-06)
    The high morbidity and mortality of hepatocellular carcinoma (HCC) has encouraged the search for new biomarkers to be used alongside alpha-foetoprotein (AFP) and imaging tests. The aim of this study was to evaluate the ...
  • Intraductal papillary neoplasms of the bile duct: a European retrospective multicenter observational study (EUR-IPNB study) 
    Lluis, Nuria; Serradilla-Martín, Mario; Achalandabaso, Mar; Jehaes, Francois; Dasari, Bobby-VM; Mambrilla-Herrero, Sara; Sparrelid, Ernesto; Balakrishnan, Anita; Hoogwater, Frederik-JH; Amaral, María-J; Andersson, Bodil; Berrevoet, Frederik; Doussot, Alexandre; López-López, Victor; Alsammani, Mohammedsuror; Detry, Olivier; Domingo-del-Pozo, Carlos; Machairas, Nikolaos; Pekli, Damjan; Alcazar-López, Candido-F; Asbun, Horacio; Bjornsson, Bergthor; Christophides, Thalis; Diez-Caballero, Alberto; Francart, David; Noel, Colin-B; Sousa-Silva, Donzilia; Toledo-Martínez, Enrique; Tzimas, George-N; Yaqub, Sheraz; Cauchy, Francois; Prieto-Calvo, Mikel; D'Souza, Melroy-A; Spiers, Harry-VM; van-den-Heuvel, Marius-C; Charco, Ramon; Lesurtel, Mickael; Ramia, José-M (LIPPINCOTT WILLIAMS & WILKINS, 2023-04)
    BACKGROUND/PURPOSE: Intraductal papillary neoplasm of the bile duct (IPNB) is a rare disease in Western countries. The main aim of this study was to characterize current surgical strategies and outcomes in the mainly ...
  • GALE variants associated with syndromic manifestations, macrothrombocytopenia, bleeding, and platelet dysfunction 
    Marin-Quilez, Ana; Di-Buduo, Christian-A; Benito, Rocio; Balduini, Alessandra; Rivera, José; Bastida, José-María (TAYLOR & FRANCIS INC, 2023-12-31)
    GALE gene encodes the uridine diphosphate [UDP]-galactose-4-epimerase, which catalyzes the bidirectional interconversion of UDP-glucose to UDP-galactose, and UDP-N-acetyl-glucosamine to UDP-N-acetyl-galactosamine. In that ...
  • Gaucher disease protects against tuberculosis 
    Fan, Jingwen; Hale, Victoria-L; Lelieveld, Lindsey-T; Whitworth, Laura-J; Busch-Nentwich, Elisabeth-M; Troll, Mark; Edelstein, Paul-H; Cox, Timothy-M; Roca, Francisco-J; Aerts, Johannes-MFG; Ramakrishnan, Lalita (NATL ACAD SCIENCES, 2023-02)
    Biallelic mutations in the glucocerebrosidase (GBA1) gene cause Gaucher disease, characterized by lysosomal accumulation of glucosylceramide and glucosylsphingosine in macrophages. Gaucher and other lysosomal diseases occur ...
  • Training, detraining and retraining effects of moderate vs. high intensity exercise training programme on cardiovascular risk factors 
    Avila-Gandia, Vicente; Ramos-Campo, Domingo-Jesus; García-Sánchez, Esther; Luque-Rubia, Antonio-Jesus; López, Asensio; López-Roman, Francisco-Javier (LIPPINCOTT WILLIAMS & WILKINS, 2023-03)
    BACKGROUND: The aim of the present study was to analyse the effect of 12 weeks of training, 7 weeks of detraining and 16 weeks of retraining using a moderate or high intensity training programme on cardiovascular risk ...
  • Patient selection, peri-procedural management, and ablation techniques for catheter ablation of atrial fibrillation: an EHRA survey 
    Iliodromitis, Konstantinos; Lenarczyk, Radoslaw; Scherr, Daniel; Conte, Giulio; Farkowski, Michal-M; Marín, Francisco; García-Seara, Javier; Simovic, Stefan; Potpara, Tatjana (OXFORD UNIV PRESS, 2023-02)
    Catheter ablation (CA) of atrial fibrillation (AF) is the therapy of choice for the maintenance of sinus rhythm in patients with symptomatic AF. Time towards interventional treatment and peri-procedural management of ...
  • Sleep quality among inpatients of Spanish public hospitals 
    Bellon, Filip; Stremler, Robyn; Rubinat-Arnaldo, Esther; Padilla-Martínez, Julia-M; Casado-Ramirez, Elvira; Sánchez-Ortuno, Montserrat; Gea-Sánchez, Montserrat; Martín-Vaquero, Yolanda; Moreno-Casbas, Teresa; Abad-Corpa, Eva (NATURE PORTFOLIO, 2022-12-20)
    Sleep is a complex process and is needed both in health and illness. Deprivation of sleep is known to have multiple negative physiological effects on people's bodies and minds. Despite the awareness of these harmful effects, ...
  • Binucleated human bone marrow-derived mesenchymal cells can be formed during neural-like differentiation with independence of any cell fusion events 
    Bueno, Carlos; Blanquer, Miguel; García-Bernal, David; Martínez, Salvador; Moraleda-Jiménez, José-María (NATURE PORTFOLIO, 2022-11)
    Although it has been reported that bone marrow-derived cells (BMDCs) can transdifferentiate into neural cells, the findings are considered unlikely. It has been argued that the rapid neural transdifferentiation of BMDCs ...
  • Anti-inflammatory potential of digested Brassica sprout extracts in human macrophage-like HL-60 cells 
    García-Ibanez, Paula; Nunez-Sánchez, María-A; Oliva-Bolarin, Alba; Martínez-Sánchez, María-A; Ramos-Molina, Bruno; Ruiz-Alcaraz, Antonio-J; Moreno, Diego-A (ROYAL SOC CHEMISTRY, 2023-01-03)
    Cruciferous vegetables have been reported to be a great source of anti-inflammatory compounds. Specifically, sprouts from the Brassicaceae family stand out for their high content of glucosinolates (and their bioactive ...
  • Contemporary management of atrial fibrillation and the predicted vs. absolute risk of ischaemic stroke despite treatment: a report from ESC-EHRA EORP-AF Long-Term General Registry 
    Ding, Wern-Yew; Blomstrom-Lundqvist, Carina; Fauchier, Laurent; Marín, Francisco; Potpara, Tatjana-S; Boriani, Giuseppe; Lip, Gregory-YH (OXFORD UNIV PRESS, 2023-02)
    BACKGROUND: Risk stratification in patients with atrial fibrillation (AF) is important to facilitate guideline-directed therapies. The Calculator of Absolute Stroke Risk (CARS) scheme enables an individualized estimation ...
  • Androgen receptor polyQ alleles and COVID-19 severity in men: A replication study 
    López-Rodríguez, Rosario; Ruiz-Hornillos, Javier; Corton, Marta; Almoguera, Berta; Minguez, Pablo; Elena-Pérez-Tomás, María; Barreda-Sánchez, María; Mancebo, Esther; Ondo, Lorena; Martínez-Ramas, Andrea; Fernández-Caballero, Lidia; Carlos-Taracido-Fernández, Juan; Herrero-González, Antonio; Mahillo, Ignacio; Paz-Artal, Estela; Guillén-Navarro, Encarna; Ayuso, Carmen (WILEY, 2023-01)
    BACKGROUND: Ample evidence indicates a sex-related difference in severity of COVID-19, with less favorable outcomes observed in men. Genetic factors have been proposed as candidates to explain this difference. The polyglutamine ...

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