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Envíos recientes

02.06.01. Investigación y comunicación científica: Envíos recientes

  • Vacunación frente a neumococo en la edad pediátrica 
    Iofrío-de-Arce, Antonio (2024-10-03)
  • Co-mutation signatures are age-dependent and impact the prognosis in NPM1-mutated acute myeloid leukemia: a PETHEMA multicenter study. 
    Gil, José-Vicente; Sargas, Claudia; Ayala, Rosa; Gutiérrez, Norma-Carmen; Pérez-Simon, José-Antonio; Gómez-Casares, María-Teresa; Larrayoz, María-José; Prados-de-la-Torre, Esther; Cano-Ferri, Isabel; Navarro, Irene; Gil, Cristina; Bernal, Teresa; Rodríguez-Arboli, Eduardo; Pérez-Santaolalla, Esther; Colmenares, Rafael; Tormo, Mar; Bergua, Juan; Amigo, María-Luz; Rodríguez-Medina, Carlos; Serrano, Josefina; Oliva, Ana-Yurena; Alonso-Domínguez, Juan-Manuel; Noriega, Víctor; Algarra, Lorenzo; Olave, María-Teresa; García-Pérez, María-José; Couto, Carmen; Almela, Agata; García-Fortes, María; Madrigal, María-Dolores; Hermosin, María-Lourdes; Colorado, Mercedes; García-Boyero, Raimundo; Ibáñez, Francisco; Sole, María; Martínez-Chamorro, Carmen; Mateos, María-Del-Carmen; García-Garay, María-Del-Carmen; Solana-Altabella, Antonio; Martin-Herreros, Beatriz; Martínez-López, Joaquín; Chillón, María-Del-Carmen; Soria, Elena; Bilbao, Cristina; Calasanz, María-José; Sánchez-García, Joaquín; Barragán, Eva; Montesinos, Pau (FERRATA STORTI FOUNDATION, 2026-07-16)
    NPM1-mutated acute myeloid leukemia is genetically heterogeneous, and risk assessment remains focused exclusively on FLT3-ITD despite the potential role of other co-mutations. We retrospectively analyzed 1,360 adults from ...
  • Mutational profile and cardiovascular risk factors impact prognosis in triple-negative essential thrombocythemia 
    Carreño-Tarragona, Gonzalo; Gil-Manso, Rodrigo; Hernández-Boluda, Juan-Carlos; Martínez-Ávila, José-Carlos; Bellosillo, Beatriz; Pérez-López, Raúl; Segura, Adrián; Ferrer-Marín, Francisca; Arellano-Rodrigo, Eduardo; Angona, Anna; García-Gutiérrez, Valentín; Noya, María-Soledad; Blanco, Ángela; Zamora, Lurdes; Navarro, Miguel; Senin, Alicia; Magro, Elena; Pastor-Galan, Irene; Mata-Vázquez, María-Isabel; Morales, María-Luz; Cuevas, Beatriz; Velez, Patricia; Mora, Elvira; Martínez-Bilbao, Cristina; Colmenares, Rafael; Alonso, Juan-Manuel; Pérez-Encinas, Manuel; Caballero-Navarro, Gonzalo; Cortes, Miguel-Ángel; Santaliestra, Marta; Raya, José-María; Blanco-Sánchez, Alberto; Hernández-Rivas, Jesus-María; Martínez-López, Joaquín; Ayala, Rosa; Álvarez-Larran, Alberto (SPRINGERNATURE, 2026-07-13)
    Triple-negative essential thrombocythemia (TN-ET) represents a diagnostic and therapeutic challenge. The aim of the present study was to identify prognostic factors useful for tailoring treatment. 241 TN-ET patients with ...
  • The cult of the external validation set: undertraining is only half of the radiomics validation crisis 
    García-Hidalgo, Clemente (SPRINGER, 2026-07-09)
  • CV risk: if you aren't testing ACR, you aren't seeing the full picture 
    Cebrián-Cuenca, Ana-María; Wheeler, David-C; Marx, Nikolaus; Levin, Adeera (TAYLOR & FRANCIS LTD, 2026-08-18)
    Chronic kidney disease (CKD) remains a hidden epidemic, under-recognized and under-diagnosed, despite widespread recognition of the benefits of systematic screening of at-risk individuals and early diagnosis. CKD is an ...
  • Dupilumab in Difficult-to-treat Chronic Spontaneous Urticaria: A Real-world Multicentre Cohort Study 
    Planella-Fontanillas, Nidia; Berna-Rico, Emilio; Figueras-Nart, Ignasi; Spertino, Jorge; Dols-Casanov, Lluis; Gatica-Ortega, María-Elena; Exposito-Serrano, Vicente; Lasheras-Pérez, Miguel-Antonio; Rodríguez-Serna, Mercedes; Mascaro-Jr, José-M; Mele-Ninot, Gemma; Mercader-García, Pedro; Navarro-Trivino, Francisco-José; Tous-Romero, Fatima; Elosua-González, Marta; Magdaleno-Tapial, Jorge; Pérez-Ferriols, Amparo; Montero-Vilchez, Trinidad; Torne-Gutiérrez, José-Ignacio; Gallardo, Fernando; Pesque, David; Pujol, Ramón-M; Serra-Baldrich, Esther; Giménez-Arnau, Ana-María (ACTA DERMATO-VENEREOLOGICA, 2026-07-06)
    Chronic spontaneous urticaria (CSU) remains difficult to manage in patients refractory to antihistamines and omalizumab. Although dupilumab has recently been approved and incorporated into international guidelines, real-world ...
  • The peripheral immune landscape of human breast cancer 
    García-Torralba, Esmeralda; Buque, Aitziber; Galluzzi, Lorenzo (TAYLOR & FRANCIS INC, 2026-12-31)
    The clinical management of patients with breast cancer is largely dictated by tumor stage, disease subtype and (at least in some settings) specific molecular features thereof (e.g., BRCA1 mutations, PD-L1 positivity). ...
  • Platelet proteome links metabolism to reactivity in Essential Thrombocythemia. 
    Guerrero-Carreno, Xiomara; Smits, Sanne; Esteban-Lasso, Alfonso; Samiotaki, Martina; Navarro, Virtu-Calabuig; Iborra, Francisco-Jose; Rantanen, Frida; Álvarez-Larran, Alberto; Angona-Figueras, Anna; Bellosillo, Beatriz; Saen-Marin, Adolfo-J; García-Gutiérrez, Valentín; Dekkers, Dick; Demmers, Jeroen; Ferrer-Marín, Francisca; Hernández-Boluda, Juan-Carlos; Matsakas, Antonios; Benavente-Cuesta, Celina; Vandenberghe, Peter; Papadopoulos, Petros (ELSEVIER, 2026-06)
    Essential thrombocythemia (ET) is a myeloproliferative neoplasm in which JAK2, CALR, and MPL mutations are associated with distinct clinical phenotypes. Here, we analyzed the platelet proteome of ET patients by MS, combined ...
  • Common and rare variants in complement genes as biomarkers of COVID-19 infection and severity. A lesson to learn for emerging pathogens 
    de-la-Morena-Barrio, María-Eugenia; van-den-Rym, Ana; Escorial-Sanz, Olga; Corvillo, Fernando; García-Sánchez, Rosario; González-Sánchez, Laura; Muñoz-Barrera, Adrián; González-Montelongo, Rafaela; Lorenzo-Salazar, José-Miguel; Flores, Carlos; de-Andres-Martin, Ana; Rodríguez-Gallego, Carlos; Allende, Luis; Alsina, Laia; Sánchez-Ramon, Silvia; López-Collazo, Eduardo; López-Trascasa, Margarita; Sánchez-Corral, Pilar; Pérez-de-Diego, Rebeca; Corral, Javier; López-Lera, Alberto (FRONTIERS MEDIA SA, 2026-06-11)
    INTRODUCTION: The first wave of Coronavirus disease 2019 (COVID-19), driven by the global emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), severely affected Spain with high infection and mortality ...
  • Minimally invasive characterization of peripheral blood measurable residual disease in multiple myeloma using high-sensitivity detection of ctDNA by next-generation sequencing 
    Buenache, Natalia; Lasa, Marta; Arroyo-Tristán, Andrés; González, Carmen; Haertle, Larissa; Ruiz-Heredia, Yanira; Ayala, Rosa; Alonso, Rafael; Martin-Muñoz, Alejandro; Rosa-Rosa, Juan-M; González, Veronica; Calasanz, María-José; Rodríguez-Otero, Paula; Rosinol, Laura; de-Arriba-de-la-Fuente, Felipe; Ocio, Enrique-M; Oriol, Albert; González, Yolanda; Sureda, Anna; Lakhwani, Sunil; Clavero, María-E; Ibáñez, Ángela; Gómez, Clara; Orfao, Alberto; Mateos, María-Victoria; Lahuerta, Juan-J; Cedena, María-T; Blade, Joan; San-Miguel, Jesús; Puig, Noemi; Paiva, Bruno; Martínez-López, Joaquín (WILEY, 2026-06)
    Measurable residual disease assessment in bone marrow (BM-MRD) is a crucial prognostic factor in multiple myeloma (MM), but its clinical use has some caveats, such as invasiveness, poor spatial representativity, and serial ...
  • Non-invasive ventilation in severe acute respiratory failure complicating Madelung's disease: a case series and management review 
    Gomes, Bruno; Esquinas-Rodríguez, Antonio; Alwajeeh, Fares-N (FRONTIERS MEDIA SA, 2026-06-04)
    Madelung's disease (Launois-Bensaude syndrome) presents a critical challenge when managing acute respiratory failure (ARF) due to the high risk of difficult airway and failed intubation posed by symmetric cervical lipomatosis. ...
  • Real-world resource utilization, toxicity management, and efficacy outcomes of CD20 × CD3 bispecific antibodies in B-cell lymphoma: A study from the GELTAMO network 
    Bastos-Oreiro, Mariana; Iacoboni, Gloria; Navarro, Víctor; Martínez, Carolina; Manresa, Pablo; Magnano, Laura; Jiménez-Ubieto, Ana; Vázquez, Sofía; Rodríguez, María-José; Busnego, María-Teresa; del-Campo, Raquel; Paul, Pedro-José; Murillo, Ilda; Donato, Eva-María; Serna, Ángel; Luzardo, Hugo; Gómez, Pilar; Pérez-Ceballos, Elena; Mendibil, Begoña; Ramos, Sergio; García-Noblejas, Ana; González-de-Villambrosia, Sonia; Díaz, Francisco-Javier; López, Javier; Martin-Moro, Fernando; Fernández-Caldas, Paula; Fernández, Rubén; Gutiérrez, Antonio; Sánchez, Blanca; Domínguez, Nazaret; Civeira, María; Villafuerte, Paola; Olazabal, Íñigo; Zeberio, Izaskun; Barrenetxea, Cristina; Gutiérrez, Norma; Romero, Samuel; Martin-Consuegra, Sofía; Huerga, Sofia; Golbano, Nuria; Riaza, Rosaia; Hueso, José-Antonio; Martínez-Barranco, Pilar; Navarro, Belén; Villalon, Lucía; Ortega, Paula; Torres, Ana; Ormenazabal, Íñigo; Sánchez-Anton, María-Piva; Goñi, María-Ángeles; Abrisqueta, Pau; Martin-García-Sancho, Alejandro (WILEY, 2026-06)
  • Predicting failure of extubation and non-invasive respiratory support in critically ill patients: clinical complexity, limitations of traditional indices, and machine learning perspectives 
    Notaro, Salvatore; Giurazza, Roberto; Imparato, Andrea; Falso, Fabrizio; Virno, Salvatore; Iovino, Teresa-Pasqualina; Caiazzo, Marco; Golino, Ludovica; Russo, Gianmarco; Di-Costanzo, Emilio; Barberio, Massimiliano; Sorrentino, Marcello; Fiorentino, Giuseppe; La-Cerra, Giuseppe; Esposito, Clelia; Corcione, Antonio; Esquinas-Rodríguez, Antonio; Piscitelli, Eugenio (FRONTIERS MEDIA SA, 2026-05-20)
    Failure of non-invasive respiratory support represents a major and unresolved clinical challenge in critically ill patients, both after extubation and during non-invasive ventilation or high-flow oxygen therapy used as ...
  • Real-World Outcomes across Baseline Risk Profiles in Patients with COPD Initiating Budesonide/Glycopyrronium/Formoterol Fumarate Dihydrate in Spain: Insights from the ORESTES Study 
    Alcazar-Navarrete, Bernardino; Figueira-Goncalves, Juan-Marco; Blanco-Cid, Nagore; Bruguera-Avila, Nuria; Bernabeu-Mora, Roberto; Fuster-Gomila, Antonia; Galera-Martínez, Raúl; García-Clemente, Marta-M; Granados, Galo; Khadour-Khadour, Hassan; Márquez-Martín, Eduardo; Murga-Arizabaleta, Igor; Velasco-Garrido, José-Luis; Corregidor-García, Carmen; Fitas, Eunice; Sánchez-Covisa, Joaquín (SPRINGERNATURE, 2026-06)
    INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is a progressive lung disorder characterized by persistent symptoms such as dyspnea and cough, as well as exacerbations. Triple therapy with budesonide/glycopyrr ...
  • Real-world effectiveness and safety of tralokinumab in moderate-to-severe atopic dermatitis with malignancy, chronic infections, and multimorbidity 
    Melgosa-Ramos, Francisco-Javier; Mercader-García, Pedro; Santos-Alarcon, Sergio; Domínguez-Liron, Nalia; Bernabeu, Andrea; Rodríguez-Serna, Mercedes; Fernández-Crehuet, Pablo; Silvestre, Juan-Francisco (ADIS INT LTD, 2026-07)
    INTRODUCTION: Patients with moderate-to-severe atopic dermatitis (AD) and significant comorbidities are frequently excluded from randomized clinical trials, limiting the applicability of evidence to these clinically complex ...
  • Efficacy and Safety of Dupilumab in Immune Checkpoint Inhibitor Induced Bullous Pemphigoid: A Spanish Multicentric Case Series 
    Tejero-García, Cecilia; Reig, Francesc-Alamon; Bosch-Amate, Xavier; Carrera, Cristina; Giavedoni, Priscila; Gil-Faure, Inmaculada; Jiménez-Antón, Alicia; Mayor-Ibarguren, Ander; Barcena, Teresa-Usero; Álvarez-Salafranca, Marcial; Gamissans-Canada, Marta; López-Robles, Joaquín; Martínez-Fernández, Sandra; Segura, Sonia; Sánchez-Aguilar-Rojas, Dolores; Florez, Ángeles (ACTA DERMATO-VENEREOLOGICA, 2026-05-21)
    Immune checkpoint inhibitors (ICIs) have signifi-cantly improved oncologiconcological outcomes. However, ICIs can elicit immune-mediated adverse effects that may require treatment discontinuation and potentially affect ...
  • Concordant epigenetic and discordant clinical PHP1B/iPPSD3 manifestations in two monozygotic adolescent twins. 
    Pérez-Nanclares, Gustavo; Manero-Azua, Africa; Grau, Gema; Pereda, Arrate; Corcuera, June; Navarro, Esther; Aranaga-Decori, Ainhoa-Camille; García-Castaño, Alejandro; de-la-Morena-Barrio, Belén; Castaño, Luis; Pérez-de-Nanclares, Guiomar (SPRINGER, 2026-05-19)
    BACKGROUND: Imprinting disorders are caused by epigenetic alterations leading to abnormal gene expression from imprinted loci. Pseudohypoparathyroidism type 1B is characterized by methylation defects at the GNAS locus, ...
  • Phase IIB, Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Intravenous Defibrotide for the Prevention and Treatment of Respiratory Distress and Cytokine Release Syndrome in COVID-19 
    Jara-Rubio, Rubén; Martínez-Mellado, Antonio-José; Kiwitt-Cardenas, Jonathan; Clavel, José-G; García-Pérez, Bartolomé; Castro, Pedro; Díaz-Ricart, Maribel; Carrillo-Alcaraz, Andrés; López-Bernus, Amparo; Bernal-Morell, Enrique; Roura, Aychel; Marín, Sonia; Ruiz-López, Francisco-José; Solana-Martínez, Elena; Martínez-Baño, Domingo; Albacete-Moreno, Carlos-L; Andreu-Soler, Enriqueta; Tellez-Santoyo, Adrián; Fernández-Méndez, Sara; Noguera-Velasco, José-Antonio; Cebreiros-López, Iria; Parrilla, Andrés; Espuny-Miró, Alberto; García-Bernal, David; Blanquer-Blanquer, Miguel; Sánchez-Salinas, Andrés; Iniesta-Martínez, Francisca; Hernández-García, Cristina; Muro-Amador, Manuel; Minguela-Puras, Alfredo; Moreno-Docón, Antonio; Torres-Cantero, Alberto; Muñoz-García, María; Serrano, Manuel; Iacobelli, Massimo; Carlo-Stella, Carmelo; Wei, Lee-Jen; Richardson, Paul-G; Moraleda-Jiménez, José-María (WILEY, 2026-05-12)
    INTRODUCTION: Endothelial dysfunction is key in COVID-19 pathogenesis. This randomized, double-blind phase IIb trial investigated continuous intravenous infusion of defibrotide in patients hospitalized with SARS-CoV-2 ...
  • Caries Prevalence in Patients With Autism Spectrum Disorder: A Review of the Literature 
    Chahmi-Tahiri, Chaima; Pecci-Lloret, María-Pilar; García-Rios, Paula; Pérez-Guzman, Nuria (WILEY, 2026-05)
    AIM: The aim of this review is to present a qualitative synthesis of various studies concerning the presence of caries in people with ASD. METHODS AND RESULTS: A review of scientific articles was carried out by consulting ...
  • Impact of thrombosis on disease progression, cancer and mortality in patients with essential thrombocythemia and polycythemia vera 
    Angona, A; Cuevas, B; Pérez-Encinas, M; Ferrer-Marín, Francisca; Senin, A; Arellano-Rodrigo, Eduardo; Hernández-Boluda, Juan-Carlos; Mata-Vázquez, M-I; Caballero-Navarro, G; Gómez-Casares, María-Teresa; Magro, E; Carreño-Tarragona, Gonzalo; Cortes-Vázquez, MA; Pérez-López, R; García-Gutiérrez, V; Noya-Pereira, M-S; Alonso-Domínguez, JM; Sierra-Aisa, C; Fox, L; García-Hernández, C; Guerra, JM; Cerezo, E; Gasior, M; Santaliestra, M; Díez, I; Cuevas, M-V; Sanz, L; Pastor, I; Stuckey, R; Velez, P; Auria-Caballero, C; Álvarez-Larran, A (SPRINGERNATURE, 2026-05-07)

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