• The genomic profiling of high-risk smoldering myeloma patients treated with an intensive strategy unveils potential markers of resistance and progression 

  Medina-Herrera, A; Vázquez, I; Cuenca, I; Rosa-Rosa, Juan-Manuel; Ariceta, B; Jiménez, C; Fernández-Mercado, M; Larrayoz, María-J; Gutiérrez, NC; Fernández-Guijarro, M; González-Calle, Verónica; Rodríguez-Otero, Paula; Oriol, Albert; Rosiñol, Laura; Alegre, A; Escalante, F; de-la-Rubia, J; Teruel, Ana-Isabel; de-Arriba-de-la-Fuente, Felipe; Hernández, MT; López-Jiménez, J; Ocio, Enrique-M; Puig, Noemi; Paiva, Bruno; Lahuerta, Juan-José; Blade, Joan; San-Miguel, JF; Mateos, María-Victoria; Martínez-López, Joaquín; Calasanz, María-José; García-Sanz, R; Ríos, R; Sureda, A; Blanchard, María-Jesús; Martínez-Martínez, R; Moraleda-Jiménez, José-María; Bargay, J; Gironella, M; Palomera, Luis; González-Montes, Y; Martí, JM; Krsnik, Isabel; Arguinano, JM; González, ME; González, AP; Casado-Montero, Luis-Felipe (SPRINGERNATURE, 2024-04-29)

  Smoldering multiple myeloma (SMM) precedes multiple myeloma (MM). The risk of progression of SMM patients is not uniform, thus different progression-risk models have been developed, although they are mainly based on clinical ...
• State of the scientific evidence and recommendations for the management of older patients with gastric cancer 

  Paredero-Pérez, Irene; Jiménez-Fonseca, Paula; Cano, Juana-María; Arrazubi, Virginia; Carmona-Bayonas, Alberto; Covela-Rua, Marta; Fernández-Montes, Ana; Martín-Richard, Marta; Gironés-Sarrio, Regina (ELSEVIER, 2024-04)

  Gastric cancer is one of the most frequent and deadly tumours worldwide. However, the evidence that currently exists for the treatment of older adults is limited and is derived mainly from clinical trials in which older ...
• Large T cell clones expressing immune checkpoints increase during multiple myeloma evolution and predict treatment resistance 

  Botta, Cirino; Pérez, Cristina; Larrayoz, Marta; Puig, Noemi; Cedena, María-Teresa; Termini, Rosalinda; Goicoechea, Ibai; Rodríguez, Sara; Zabaleta, Aintzane; López, Aitziber; Sarvide, Sarai; Blanco, Laura; Papetti, Daniele-M; Nobile, Marco-S; Besozzi, Daniela; Gentile, Massimo; Correale, Pierpaolo; Siragusa, Sergio; Oriol, Albert; González-García, María-Esther; Sureda, Anna; de-Arriba-de-la-Fuente, Felipe; Ríos-Tamayo, Rafael; Moraleda-Jiménez, José-María; Gironella, Mercedes; Hernández-García, Miguel-Teodoro; Bargay, Joan; Palomera, Luis; Pérez-Montana, Albert; Goldschmidt, Hartmut; Avet-Loiseau, Herve; Roccaro, Aldo; Orfao, Alberto; Martínez-López, Joaquín; Rosiñol, Laura; Lahuerta, Juan-José; Blade, Joan; Mateos, María-Victoria; San-Miguel, Jesús-F; Martínez-Climent, José-Ángel; Paiva, Bruno (NATURE PORTFOLIO, 2023-09)

  Tumor recognition by T cells is essential for antitumor immunity. A comprehensive characterization of T cell diversity may be key to understanding the success of immunomodulatory drugs and failure of PD-1 blockade in tumors ...
• Scalable production of tissue-like vascularized liver organoids from human PSCs 

  Harrison, Sean-P; Siller, Richard; Tanaka, Yoshiaki; Chollet, María-Eugenia; de-la-Morena-barrio, María-Eugenia; Xiang, Yangfei; Patterson, Benjamin; Andersen, Elisabeth; Bravo-Pérez, Carlos; Kempf, Henning; Asrud, Kathrine-S; Lunov, Oleg; Dejneka, Alexandr; Mowinckel, Marie-Christine; Stavik, Benedicte; Sandset, Per-Morten; Melum, Espen; Baumgarten, Saphira; Bonanini, Flavio; Kurek, Dorota; Mathapati, Santosh; Almaas, Runar; Sharma, Kulbhushan; Wilson, Steven-R; Skottvoll, Froydis-S; Boger, Ida-C; Bogen, Inger-Lise; Nyman, Tuula-A; Wu, Jun-Jie; Bezrouk, Ales; Cizkova, Dana; Corral, Javier; Mokry, Jaroslav; Zweigerdt, Robert; Park, In-Hyun; Sullivan, Gareth-J (SPRINGERNATURE, 2023-09)

  The lack of physiological parity between 2D cell culture and in vivo culture has led to the development of more organotypic models, such as organoids. Organoid models have been developed for a number of tissues, including ...
• Durvalumab plus tremelimumab for the treatment of advanced neuroendocrine neoplasms of gastroenteropancreatic and lung origin 

  Capdevila, Jaume; Hernando, J; Teule, A; López, C; García-Carbonero, R; Benavent, M; Custodio, Ana-Belén; García-Álvarez, A; Cubillo, A; Alonso, V; Carmona-Bayonas, Alberto; Alonso-Gordoa, T; Crespo, G; Jiménez-Fonseca, Paula; Blanco, M; Viudez, A; La-Casta, Adelaida; Sevilla, I; Segura, A; Llanos, M; Landolfi, S; Nuciforo, P; Manzano, José-L (NATURE PORTFOLIO, 2023-05)

  Single immune checkpoint blockade in advanced neuroendocrine neoplasms (NENs) shows limited efficacy; dual checkpoint blockade may improve treatment activity. Dune (NCT03095274) is a non-randomized controlled multicohort ...
• Comparison of the 2022 and 2017 European LeukemiaNet risk classifications in a real-life cohort of the PETHEMA group 

  Sargas, Claudia; Ayala, Rosa; Larrayoz, María-J; Chillón, María-del-Carmen; Rodríguez-Arboli, Eduardo; Bilbao, Cristina; Prados-de-la-Torre, Esther; Martínez-Cuadrón, David; Rodríguez-Veiga, Rebeca; Boluda, Blanca; Gil, Cristina; Bernal, Teresa; Bergua, Juan; Algarra, Lorenzo; Tormo, Mar; Martínez-Sánchez, Pilar-M; Soria, Elena; Serrano, Josefina; Alonso-Domínguez, Juan; García, Raimundo; Amigo, María-Luz; Herrera-Puente, Pilar; Sayas, María-José; Lavilla-Rubira, Esperanza; Martínez-López, Joaquín; Calasanz, María-José; García-Sanz, Ramón; Pérez-Simon, José-Antonio; Casares, María-TGómez; Sánchez-García, Joaquín; Barragan, Eva; Montesinos, Pau (SPRINGERNATURE, 2023-05)

  Next-Generation Sequencing is needed for the accurate genetic risk stratification of acute myeloid leukemia according to European LeukemiaNet (ELN) guidelines. We validated and compared the 2022 ELN risk classification in ...
• Impact of particulate matter on the incidence of atrial fibrillation and the risk of adverse clinical outcomes: A review 

  Mandaglio-Collados, Dario; López-Gálvez, Raquel; Ruiz-Alcaraz, Antonio-José; López-García, Cecilia; Roldán-Schilling, Vanesa; Lip, Gregory-YH; Marín, Francisco; Rivera-Caravaca, José-Miguel (ELSEVIER, 2023-07)

  BACKGROUND: Atrial fibrillation (AF) is common and increases the risk of stroke and mortality. Previous studies have suggested that air pollution is an important risk factor for new-onset AF. Herein, we review the evidence ...
• von Willebrand factor links primary hemostasis to innate immunity 

  Drakeford, Clive; Águila, Sonia; Roche, Fiona; Hokamp, Karsten; Fazavana, Judicael; Cervantes, Mariana-P; Curtis, Annie-M; Hawerkamp, Heike-C; Dhami, Sukhraj-Pal-Singh; Charles-Messance, Hugo; Hackett, Emer-E; Chion, Alain; Ward, Soracha; Ahmad, Azaz; Schoen, Ingmar; Breen, Eamon; Keane, Joe; Murphy, Ross; Preston, Roger-JS; O'Sullivan, Jamie-M; Sheedy, Frederick-J; Fallon, Padraic; O'Donnell, James-S (NATURE PORTFOLIO, 2022-11)

  The plasma multimeric glycoprotein von Willebrand factor (VWF) plays a critical role in primary hemostasis by tethering platelets to exposed collagen at sites of vascular injury. Recent studies have identified additional ...
• Non-invasive ventilation in post-extubation respiratory failure due to Reinke's edema 

  Araujo, MJ; Esquinas-Rodríguez, Antonio; Carrillo, A (ELSEVIER, 2022-07)
• Genetic polymorphisms associated with telomere length and risk of developing myeloproliferative neoplasms 

  Giaccherini, Matteo; Macauda, Angélica; Sgherza, Nicola; Sainz, Juan; Gemignani, Federica; Sánchez-Maldonado, José-Manuel; Jurado, Manuel; Tavano, Francesca; Mazur, Grzegorz; Jerez-Cayuela, Andrés; Gora-Tybor, Joanna; Golos, Aleksandra; Mohedo, Francisca-Hernández; López, Joaquín; Varkonyi, Judit; Spadano, Raffaele; Butrym, Aleksandra; Canzian, Federico; Campa, Daniele (NATURE PUBLISHING GROUP, 2020-09)

  Telomere length measured in leukocyte (LTL) has been found to be associated with the risk of developing several cancer types, including myeloproliferative neoplasms (MPNs). LTL is genetically determined by, at least, 11 ...
• Plasma tumour DNA as an early indicator of treatment response in metastatic castration-resistant prostate cancer 

  Conteduca, Vincenza; Wetterskog, Daniel; Scarpi, Emanuela; Romanel, Alessandro; Gurioli, Giorgia; Jayaram, Anuradha; Lolli, Cristian; Tandefelt, Delila-Gasi; Schepisi, Giuseppe; Casadei, Chiara; Wingate, Anna; Matteucci, Federica; Paganelli, Giovanni; González-Billalabeitia, Enrique; Demichelis, Francesca; de-Giorgi, Ugo; Attard, Gerhardt (SPRINGERNATURE, 2020-09)

  BACKGROUND: Plasma tumour DNA (ptDNA) levels on treatment are associated with response in a variety of cancers. However, the role of ptDNA in prostate cancer monitoring remains largely unexplored. Here we characterised ...
• Comparative Biological Properties and Mineralization Potential of 3 Endodontic Materials for Vital Pulp Therapy: Theracal PT, Theracal LC, and Biodentine on Human Dental Pulp Stem Cells 

  Sanz, José-Luis; Soler-Doria, Anna; López-García, Sergio; García-Bernal, David; Rodríguez-Lozano, Francisco-Javier; Lozano, Adrián; Llena, Carmen; Forner, Leopoldo; Guerrero-Gironés, Julia; Melo, María (ELSEVIER SCIENCE INC, 2021-12)

  INTRODUCTION: The aim of this study was to assess the biological properties and mineralization potential of the new Theracal PT (Bisco Inc, Schaumburg, IL) compared with its predecessor Theracal LC (Bisco Inc) and the ...
• Current status of diagnosis and treatment of heparin-induced thrombocytopenia (HIT) 

  Paramo, José-A; Lozano-Almela, María-Luisa; González-Porras, José-Ramón; Mateo, José (ELSEVIER ESPANA SLU, 2022-01-21)
• Lenalidomide and dexamethasone with or without clarithromycin in patients with multiple myeloma ineligible for autologous transplant: a randomized trial 

  Puig, Noemi; Hernández-García, Miguel-Teodoro; Rosiñol, Laura; González, Esther; de-Arriba-de-la-Fuente, Felipe; Oriol, Albert; González-Calle, Verónica; Escalante, Fernando; de-la-Rubia, Javier; Gironella, Mercedes; Ríos, Rafael; García-Sánchez, Ricarda; Arguiáano, José-M; Alegre, Adrián; Martín, Jesús; Gutiérrez, NormaC; Calasanz, María-José; Martín, María-L; Couto, María-del-Carmen; Casanova, María-José; Arnao, Mario; Pérez-Persona, Ernesto; Garzon, Sebastián; González, Marta-S; Martín-Sánchez, Guillermo; Ocio, Enrique-M; Coleman, Morton; Encinas, Cristina; Vale, Ana-M; Teruel, Ana-Isabel; Cortes-Rodríguez, María; Paiva, Bruno; Cedena, María-Teresa; San-Miguel, Jesús-F; Lahuerta, Juan-José; Blade, Joan; Niesvizky, Rubén; Mateos, María-Victoria (SPRINGERNATURE, 2021-05)

  Although case-control analyses have suggested an additive value with the association of clarithromycin to continuous lenalidomide and dexamethasone (Rd), there are not phase III trials confirming these results. In this ...
• The effect of the discrepancy between pre- and post-operative staging on decision-making and quality of life in men undergoing a radical prostatectomy 

  Martínez-Bordajandi, Álvaro; Puga-Mendoza, Ana-Patricia; Granero-Heredia, Gonzalo; Fernández-Sola, Cayetano; Fernández-Aparicio, Tomás; Dobarrio-Sanz, Iria; Hernández-Padilla, José-Manuel (MRE PRESS, 2023-07)
• Unravelling Transplant-Ineligible Newly Diagnosed Multiple Myeloma Treatment in Real-World Practice in Spain: The CARINAE Study 

  de-Arriba-de-la-Fuente, Felipe; Gironella-Mesa, Mercedes; Hernández-García, Miguel-Teodoro; Soler-Campos, Juan-Alonso; Herráez-Rodríguez, Susana; Moreno-Belmonte, María-José; Regueiro-López, Teresa; González-Pardo, Miriam; Espinosa, María-Casanova (MDPI, 2024-10)

  Real-world evidence on the impact of monoclonal antibodies as first-line treatment in Spain is limited. This observational, retrospective and prospective, multicenter, descriptive study included 117 transplant-ineligible ...
• The Attitudes of Healthcare Professionals in an Autonomous Community in Spain towards Paediatric Influenza Vaccination 

  Pérez-Martín, Jaime-Jesús; Iofrio-de-Arce, Antonio; Zornoza-Moreno, Matilde (MDPI, 2024-06)

  In the 2022-2023 influenza season, three autonomous communities anticipated the document approved by the Public Health Commission recommending influenza vaccination for all children aged 6 to 59 months. The primary objective ...
• Comparative Cytotoxicity of Menthol and Eucalyptol: An In Vitro Study on Human Gingival Fibroblasts 

  Puig-Herreros, Clara; Sanz, José-Luis; García-Bernal, David; Rodríguez-Lozano, Francisco-Javier; Murcia, Laura; Forner, Leopoldo; Ghilotti, James; Oñate-Sánchez, Ricardo-Elías; López-García, Sergio (MDPI, 2024-04)

  The aim of this study was to assess the influence of eucalyptol and menthol on the cell viability, migration, and reactive oxygen species production of human gingival fibroblasts (GFs) in vitro. Three different concentrations ...
• An experience of integration of specialized medical training with university postgraduate learning: Stage-based training in laparoscopic surgery. 

  Flores-Funes, Diego; Pellicer-franco, Enrique; Flores-Pastor, Benito; Cascales, Matilde-Moreno; Fernández-villacanas-marin, Miguel-Ángel; Aguayo-albasini, José-Luis (UNIV MURCIA, 2020)
• Analysis of the Porosity and Microhardness of Glass Ionomer Cements 

  Cabello-Malagón, Inmaculada; Cánovas-Hernández, Basilio; Martínez-Hernández, Elisa; Serna-Muñoz, Clara; Pérez-silva, Amparo; Ortiz-Ruiz, Antonio-José (KAUNAS UNIV TECH, 2022)

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