BACKGROUND: Accumulation of metals in the human body results from the interplay between environmental exposure-primarily through diet-and genetic susceptibility. Genome-wide association studies (GWAS) enable hypothesis-free ...

BACKGROUND: Currently, three cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i) are approved in combination with endocrine therapy (ET) as first-line treatment of patients with hormone receptor (HR)-positive/human epidermal ...

BACKGROUND: Identifying sperm biomarkers that predict fertility in swine is important for improving animal selection and production. In this context, however, sperm chromatin in swine remains understudied, and whether it ...

Anticoagulant rodenticides (ARs) are globally used for rodent control, posing significant risks to non-target predators and scavengers through secondary poisoning. ARs act by inhibiting the vitamin K epoxide reductase ...

Despite the potential cancer preventive effects of flavonoids and lignans, their ability to reduce pancreatic cancer risk has not been demonstrated in epidemiological studies. Our aim was to examine the association between ...

OBJECTIVE: To investigate the chronic low back pain and coronary heart disease relationship, after adjusting for relevant confounders, including genetics. METHODS: In a cross-sectional design, 2148 twins were recruited ...