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Envíos recientes

02.06. Área de Salud VI Vega Media: Envíos recientes

  • Impact of FLT3-ITD Mutation Status and Its Ratio in a Cohort of 2901 Patients Undergoing Upfront Intensive Chemotherapy: A PETHEMA Registry Study 
    Ayala, Rosa; Carreño-Tarragona, Gonzalo; Barragan, Eva; Boluda, Blanca; Larrayoz, María-J; Chillón, María-del-Carmen; Carrillo-Cruz, Estrella; Bilbao, Cristina; Sánchez-García, Joaquín; Bernal, Teresa; Martínez-Cuadrón, David; Gil, Cristina; Serrano, Josefina; Rodríguez-Medina, Carlos; Bergua, Juan; Pérez-Simon, José-Antonio; Calbacho, María; Alonso-Dominguez, Juan-Manuel; Labrador, Jorge; Tormo, Mar; Amigo, María-Luz; Herrera-Puente, Pilar; Rapado, Inmaculada; Sargas, Claudia; Vázquez, Iria; Calasanz, María-José; Gómez-Casares, María-Teresa; García-Sanz, Ramón; Sanz, Miguel-Ángel; Martínez-López, Joaquín; Montesinos, Pau (MDPI, 2022-12)
    FLT3?ITD results in a poor prognosis in terms of overall survival (OS) and relapse-free survival (RFS) in acute myeloid leukemia (AML). However, the prognostic usefulness of the allelic ratio (AR) to select post-remission ...
  • Allogeneic Hematopoietic Stem Cell Transplantation in Transformed Follicular Lymphoma (tFL): Results of a Retrospective Multicenter Study from GELTAMO/GETH-TC Spanish Groups 
    Rey-Bua, Beatriz; Cabrero, Monica; Bento, Leyre; Montoro, Juan; Bastos-Oreiro, Mariana; Parody, Rocío; Yanez, Lucrecia; López-Godino, Oriana; Zanabili, Joud; Herrera, Pilar; Gutiérrez, Gonzalo; Pérez, Ariadna; Piñana, José-Luis; Novelli, Silvana; Cortes, María; Sureda, Anna; Caballero, Dolores; Martín-García-Sancho, Alejandro (MDPI, 2022-11)
    BACKGROUND: Transformation of follicular lymphoma into an aggressive lymphoma (tFL) worsens the prognosis and the standard treatment is not completely defined. Allogeneic hematopoietic stem cell transplantation (alloSCT) ...
  • Recurrence of Oral Leukoplakia after CO2 Laser Resection: A Prospective Longitudinal Study 
    Rodríguez-Luján, Adela; López-Jornet, Pía; Pons-Fuster-López, Eduardo (MDPI, 2022-11)
    AIM: The aim of this study is to assess the efficacy of CO(2) laser treatment in oral leukoplakia and to analyse the recurrence rate of oral leukoplakia lesions at 18-month follow-up. MATERIALS AND METHODS: A prospective ...
  • Transcriptional Profile Associated with Clinical Outcomes in Metastatic Hormone-Sensitive Prostate Cancer Treated with Androgen Deprivation and Docetaxel 
    Jiménez, Natalia; Reig, Óscar; Marín-Aguilera, Mercedes; Aversa, Caterina; Ferrer-Mileo, Laura; Font, Albert; Rodríguez-Vida, Alejo; Ángel-Climent, Miguel; Cros, Sara; Chirivella, Isabel; Domenech, Montserrat; Figols, Mariona; González-Billalabeitia, Enrique; Jiménez-Peralta, Daniel; Rodríguez-Carunchio, Leonardo; García-Esteve, Samuel; García-de-Herreros, Marta; Ribal, María-J; Prat, Aleix; Mellado, Begoña (MDPI, 2022-10)
    (1) Background: Androgen deprivation therapy (ADT) and docetaxel (DX) combination is a standard therapy for metastatic hormone-sensitive prostate cancer (mHSPC) patients. (2) Methods: We investigate if tumor transcriptomic ...
  • Optical Genome Mapping: A Promising New Tool to Assess Genomic Complexity in Chronic Lymphocytic Leukemia (CLL) 
    Puiggros, Anna; Ramos-Campoy, Silvia; Kamaso, Joanna; de-la-Rosa, Mireia; Salido, Marta; Melero, Carme; Rodríguez-Rivera, María; Bougeon, Sandrine; Collado, Rosa; Gimeno, Eva; García-Serra, Rocío; Alonso, Sara; Moro-García, Marco-Antonio; García-Malo, María-Dolores; Calvo, Xavier; Arenillas, Leonor; Ferrer, Ana; Mantere, Tuomo; Hoischen, Alexander; Schoumans, Jacqueline; Espinet, Blanca (MDPI, 2022-07)
    Novel treatments in chronic lymphocytic leukemia (CLL) have generated interest regarding the clinical impact of genomic complexity, currently assessed by chromosome banding analysis (CBA) and chromosomal microarray analysis ...
  • Characteristics and Outcomes of Adult Patients in the PETHEMA Registry with Relapsed or Refractory FLT3-ITD Mutation-Positive Acute Myeloid Leukemia 
    Martínez-Cuadrón, David; Serrano, Josefina; Mariz, José; Gil, Cristina; Tormo, Mar; Martínez-Sánchez, Pilar; Rodríguez-Arboli, Eduardo; García-Boyero, Raimundo; Rodríguez-Medina, Carlos; Martínez-Chamorro, Carmen; Polo, Marta; Bergua, Juan; Aguiar, Eliana; Amigo, María-Luz; Herrera, Pilar; Alonso-Dominguez, Juan-Manuel; Bernal, Teresa; Espadana, Ana; Sayas, María-José; Algarra, Lorenzo; Vidriales, María-B; Vasconcelos, Graca; Vives, Susana; Pérez-Encinas, Manuel-Mateo; López, Aurelio; Noriega, Víctor; García-Fortes, María; Chillón, María-del-Carmen; Rodríguez-Gutiérrez, Juan; Calasanz, María-José; Labrador, Jorge; López, Juan-A; Boluda, Blanca; Rodríguez-Veiga, Rebeca; Martínez-López, Joaquín; Barragan, Eva; Sanz, Miguel-Ángel; Montesinos, Pau (MDPI, 2022-06)
    This retrospective study investigated outcomes of 404 patients with relapsed/refractory (R/R) FMS-like tyrosine kinase 3 (FLT3)-internal tandem duplication (ITD) acute myeloid leukemia (AML) enrolled in the PETHEMA registry, ...
  • Allogeneic Stem Cell Transplantation in Mantle Cell Lymphoma; Insights into Its Potential Role in the Era of New Immunotherapeutic and Targeted Therapies: The GETH/GELTAMO Experience 
    Gutiérrez, Antonio; Bento, Leyre; Novelli, Silvana; Martín, Alejandro; Gutiérrez, Gonzalo; Queralt-Salas, María; Bastos-Oreiro, Mariana; Pérez, Ariadna; Hernani, Rafael; Viguria, María-Cruz; López-Godino, Oriana; Montoro, Juan; Piñana, José-Luis; Ferra, Christelle; Parody, Rocío; Martín, Carmen; Español-Morales, Ignacio; Yanez, Lucrecia; Rodríguez, Guillermo; Zanabili, Joud; Herrera, Pilar; Varela, María; Sampol, Antonia; Solano, Carlos; Caballero, Dolores (MDPI, 2022-06)
    Allo-SCT is a curative option for selected patients with relapsed/refractory (R/R) MCL, but with significant NRM. We present the long-term results of patients receiving allo-SCT in Spain from March 1995 to February 2020. ...
  • Prognostic and Predictive Effects of Tumor and Plasma miR-200c-3p in Locally Advanced and Metastatic Breast Cancer 
    Navarro-Manzano, Esther; Luengo-Gil, Ginés; González-Conejero, Rocío; García-Garre, Elisa; García-Martínez, Elena; García-Torralba, Esmeralda; Chaves-Benito, Asunción; Vicente, Vicente; Ayala-de-la-Peña, Francisco (MDPI, 2022-05)
    While the role of miR-200c in cancer progression has been established, its expression and prognostic role in breast cancer is not completely understood. The predictive role of miR-200c in response to chemotherapy has also ...
  • Persistent Large Granular Lymphocyte Clonal Expansions: "The Root of Many Evils"-And of Some Goodness 
    Bravo-Pérez, Carlos; Carrillo-Tornel, Salvador; García-Torralba, Esmeralda; Jerez-Cayuela, Andrés (MDPI, 2022-03)
    Large granular lymphocyte leukemia (LGLL) is a chronic disease of either mature phenotype cytotoxic CD3+ T lymphocytes or CD3- NK cells. LGLL diagnosis is hampered by the fact that reactive persistent clonal LGL expansions ...
  • Impact of Individual Comorbidities on Survival of Patients with Myelofibrosis 
    García-Fortes, María; Hernández-Boluda, Juan-Carlos; Álvarez-Larran, Alberto; Raya, José-M; Angona, Anna; Estrada, Natalia; Fox, María-Laura; Cuevas, Beatriz; García-Hernández, María-C; Gómez-Casares, María-Teresa; Ferrer-Marín, Francisca; Saavedra, Silvana; Cervantes, Francisco; García-Delgado, Regina (MDPI, 2022-05)
    The comorbidity burden is an important risk factor for overall survival (OS) in several hematological malignancies. This observational prospective study was conducted to evaluate the impact of individual comorbidities on ...
  • Role of Artificial Intelligence in the Early Diagnosis of Oral Cancer. A Scoping Review 
    García-Pola, María; Pons-Fuster-López, Eduardo; Suarez-Fernández, Carlota; Seoane-Romero, Juan; Romero-Mendez, Amparo; López-Jornet, Pía (MDPI, 2021-09)
    The early diagnosis of cancer can facilitate subsequent clinical patient management. Artificial intelligence (AI) has been found to be promising for improving the diagnostic process. The aim of the present study is to ...
  • Early Clinical Experience with Trifluridine/Tipiracil for Refractory Metastatic Colorectal Cancer: The ROS Study 
    García-Alfonso, Pilar; Munoz, Andrés; Jiménez-Castro, Jeronimo; Jiménez-Fonseca, Paula; Pericay, Carles; Longo-Muñoz, Federico; Reyna-Fortes, Carmen; Argiles-Martínez, Guillem; González-Astorga, Beatriz; Gómez-Reina, María-José; Ruiz-Casado, Ana; Rodríguez-Salas, Nuria; López-López, Rafael; Carmona-Bayonas, Alberto; Conde-Herrero, Verónica; Aranda, Enrique (MDPI, 2021-09)
    Trifluridine/tipiracil is currently approved for metastatic colorectal cancer (mCRC) refractory to available therapies. However, there is no consensus on factors that predict treatment outcomes in daily practice. We assessed ...
  • Minimal Residual Disease in Multiple Myeloma: Something Old, Something New 
    Bravo-Pérez, Carlos; Sola, María; Teruel-Montoya, Raúl; García-Malo, María-Dolores; Ortuño, Francisco-José; Vicente, Vicente; de-Arriba-de-la-Fuente, Felipe; Jerez-Cayuela, Andrés (MDPI, 2021-09)
    The game-changing outcome effect, due to the generalized use of novel agents in MM, has cre-ated a paradigm shift. Achieving frequent deep responses has placed MM among those neoplasms where the rationale for assessing MRD ...
  • SEGHI Study: Defining the Best Surveillance Strategy in Hodgkin Lymphoma after First-Line Treatment 
    Bastos-Oreiro, Mariana; Martín, Reyes; Gómez, Pilar; López-Munoz, Nieves; Rodríguez, Antonia; Liebana, Marta; Navarro, Belén; Sánchez-González, Blanca; Mari, Pilar; Pérez-de-Oteiza, Jaime; Gutiérrez, Antonio; Bento, Leyre; Domingo-Domenech, Eva; Vidal, María-Jesús; Del-Campo, Raquel; Pérez-Ceballos, Elena; Infante, María; Roldán, Alicia; García-Belmonte, Daniel; Santero, Miriam; Sureda, Anna; García-Sanz, Ramón (MDPI, 2021-05)
    The optimal strategy for early surveillance after first complete response is unclear in Hodgkin lymphoma. Thus, we compared the various follow-up strategies in a multicenter study. All the included patients had a negative ...
  • Pembrolizumab as Consolidation Strategy in Patients with Multiple Myeloma: Results of the GEM-Pembresid Clinical Trial 
    Puig, Noemi; Corchete-Sánchez, Luis-A; Pérez-Morán, José-J; Davila, Julio; Paino, Teresa; de-la-Rubia, Javier; Oriol, Albert; Martín-Sánchez, Jesús; de-Arriba-de-la-Fuente, Felipe; Blad, Joan; Blanchard, María-Jesús; González-Calle, Verónica; García-Sanz, Ramón; Paiva, Bruno; Lahuerta, Juan-José; San-Miguel, Jesús-F; Mateos, María-Victoria; Ocio, Enrique-M (MDPI, 2020-12)
    PD1 expression in CD4(+) and CD8(+) T cells is increased after treatment in multiple myeloma patients with persistent disease. The GEM-Pembresid trial analyzed the efficacy and safety of pembrolizumab as consolidation in ...
  • Physical Activity in Patients with Advanced Cancer: Sociodemographic, Clinical, and Psychological Correlates 
    Mihic-Gongora, Luka; Jiménez-Fonseca, Paula; Coca-Membribes, Sara; Cruz-Castellanos, Patricia; Galán-Moral, Rocío; Asensio-Martínez, Elena; Palacin-Lois, María; Carmona-Bayonas, Alberto; Carames-Sánchez, Cristina; Calderón, Caterina (MDPI, 2024-06)
    As cancer progresses, patients may experience physical decline, which can impair their ability to carry out essential daily tasks. The aim of this study was to analyze the levels of physical activity in patients with ...
  • Biomimetic Approaches in Clinical Endodontics 
    Kumar, Naresh; Maher, Nazrah; Amin, Faiza; Ghabbani, Hani; Zafar, Muhammad-Sohail; Rodríguez-Lozano, Francisco-Javier; Oñate-Sánchez, Ricardo-Elías (MDPI, 2022-12)
    In the last few decades, biomimetic concepts have been widely adopted in various biomedical fields, including clinical dentistry. Endodontics is an important sub-branch of dentistry which deals with the different conditions ...
  • Anti-Tumor Functions of Prelatent Antithrombin on Glioblastoma Multiforme Cells 
    Peñas-Martínez, Julia; Luengo-Gil, Ginés; Espin, Salvador; Bohdan, Nataliya; Ortega-Sabater, Carmen; Ródenas, María-del-Carmen; Zaragoza-Huesca, David; López-Andreo, María-José; Plasencia, Carme; Vicente, Vicente; Carmona-Bayonas, Alberto; Martínez-Martínez, Irene (MDPI, 2021-05)
    Antithrombin, the main physiological inhibitor of the coagulation cascade, exerts anti-tumor effects on glioblastoma multiforme cells. Antithrombin has different conformations: native, heparin-activated, prelatent, latent, ...
  • Proteomics-Based Identification of Salivary Changes in Patients with Burning Mouth Syndrome 
    Castillo-Felipe, Candela; Franco-Martínez, Lorena; Tvarijonaviciute, Asta; López-Jornet, Pía; Lamy, Elsa (MDPI, 2021-05)
    Burning mouth syndrome (BMS) is a chronic oral condition characterized by an intraoral burning sensation, taste alterations, and dry mouth sensations. Although a number of factors have been closely related to the appearance ...
  • Immunotherapy in Acute Myeloid Leukemia: A Literature Review of Emerging Strategies 
    Guarnera, Luca; Bravo-Pérez, Carlos; Visconte, Valeria (MDPI, 2023-10)
    In the last twenty years, we have witnessed a paradigm shift in the treatment and prognosis of acute myeloid leukemia (AML), thanks to the introduction of new efficient drugs or approaches to refine old therapies, such as ...

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