Repositorio Dspace

Envíos recientes

03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla): Envíos recientes

  • The RS4939827 polymorphism in the SMAD7 GENE and its association with Mediterranean diet in colorectal carcinogenesis 
    Alonso-Molero, Jessica; González-Donquiles, Carmen; Palazuelos, Camilo; Fernández-Villa, Tania; Ramos, Elena; Pollan, Marina; Aragonés, Nuria; Llorca, Javier; Henar-Alonso, M; Tardon, Adonina; Amiano, Pilar; Jiménez-Moleon, José-Juan; Peiro-Pérez, Rosana; Capelo, Rocío; Molina, Antonio-J; Gómez-Acebo, Inés; Guevara, Marcela; Pérez-Gómez, Beatriz; Lope, Virginia; Huerta-Castaño, José-María; Castaño-Vinyals, Gemma; Kogevinas, Manolis; Moreno, Víctor; Martín, Vicente (BMC, 2017-10-30)
    BACKGROUND: The objective of our investigation is to study the relationship between the rs4939827 SNP in the SMAD7 gene, Mediterranean diet pattern and the risk of colorectal cancer. METHODS: We examined 1087 cases of ...
  • Validity of self blood pressure measurement in the control of the hypertensive patient: factors involved 
    de-Leon-Robert, Arleen; Gascón-Cánovas, Juan-José; Joaquin-Anton-Botella, José; Hidalgo-García, Isabel-María; López-Alegría, Carmen; Dilvani-Pérez-Cabrera, Yoalys; Merari-Campusano-Castellanos, Heidy (BMC, 2019-07-17)
    BACKGROUND: Improving clinical practice aimed at controlling hypertension is a pending issue in health systems. One of the methods currently used for this purpose is self blood pressure measurement (SBPM) whose use increases ...
  • CD33 (Siglec-3) Inhibitory Function: Role in the NKG2D/DAP10 Activating Pathway 
    Hernández-Caselles, Trinidad; Corral-San-Miguel, Rubén; Ruiz-Alcaraz, Antonio-José; García-Peñarrubia, Pilar (HINDAWI LTD, 2019)
    CD33 (siglec-3), a well-known target in leukemia therapy, is an inhibitory sialoadhesin expressed in human leukocytes of the myeloid lineage and some lymphoid subsets, including NK cells. It may constitute a control mechanism ...
  • Exploring causality of the association between smoking and Parkinson's disease 
    Gallo, Valentina; Vineis, Paolo; Cancellieri, Mariagrazia; Chiodini, Paolo; Barker, Roger-A; Brayne, Carol; Pearce, Neil; Vermeulen, Roel; Panico, Salvatore; Bueno-de-Mesquita, Bas; Vanacore, Nicola; Forsgren, Lars; Ramat, Silvia; Ardanaz, Eva; Arriola, Larraitz; Peterson, Jesper; Hansson, Oskar; Gavrila-Chervase, Diana; Sacerdote, Carlotta; Sieri, Sabina; Kuehn, Tilman; Katzke, Verena-A; van-der-Schouw, Yvonne-T; Kyrozis, Andreas; Masala, Giovanna; Mattiello, Amalia; Perneczky, Robert; Middleton, Lefkos; Saracci, Rodolfo; Riboli, Elio (OXFORD UNIV PRESS, 2019-06)
    BACKGROUND: The aim of this paper is to investigate the causality of the inverse association between cigarette smoking and Parkinson's disease (PD). The main suggested alternatives include a delaying effect of smoking, ...
  • Cohort Profile: Nausea and vomiting during pregnancy genetics consortium (NVP Genetics Consortium) 
    Colodro-Conde, Lucía; Cross, Simone-M; Lind, Penelope-A; Painter, Jodie-N; Gunst, Annika; Jern, Patrick; Johansson, Ada; Maegbaek, Merete-Lund; Munk-Olsen, Trine; Nyholt, Dale-R; Ordoñana, Juan-Ramón; Paternoster, Lavinia; Sánchez-Romera, Juan-F; Wright, Margaret-J; Medland, Sarah-E (OXFORD UNIV PRESS, 2017-04)
  • Gearing up to handle the mosaic nature of life in the quest for orthologs 
    Forslund, Kristoffer; Pereira, Cecile; Capella-Gutierrez, Salvador; Sousa-da-Silva, Alan; Altenhoff, Adrian; Huerta-Cepas, Jaime; Muffato, Matthieu; Patricio, Mateus; Vandepoele, Klaas; Ebersberger, Ingo; Blake, Judith; Fernández-Breis, Jesualdo-Tomás; Boeckmann, Brigitte; Gabaldon, Toni; Sonnhammer, Erik; Dessimoz, Christophe; Lewis, Suzanna (OXFORD UNIV PRESS, 2018-01-15)
    The Quest for Orthologs (QfO) is an open collaboration framework for experts in comparative phylogenomics and related research areas who have an interest in highly accurate orthology predictions and their applications. We ...
  • The role of plasma microseminoprotein-beta in prostate cancer: an observational nested case-control and Mendelian randomization study in the European prospective investigation into cancer and nutrition 
    Byrne, K-Smith; Appleby, P-N; Key, T-J; Holmes, M; Fensom, G-K; Agudo, A; Ardanaz, Eva; Boeing, H; Bueno-de-Mesquita, Bas; Chirlaque-López, María-Dolores; Kaaks, R; Larrañaga, N; Palli, D; Pérez-Cornago, A; Quirós, José-Ramón; Ricceri, F; Sánchez, M-J; Tagliabue, G; Tsilidis, K-K; Tumino, R; Fortner, R-T; Ferrari, P; Riboli, Elio; Lilja, H; Travis, R-C (OXFORD UNIV PRESS, 2019-06)
    BACKGROUND: Microseminoprotein-beta (MSP), a protein secreted by the prostate epithelium, may have a protective role in the development of prostate cancer. The only previous prospective study found a 2% reduced prostate ...
  • Androgen receptor gene status in plasma DNA associates with worse outcome on enzalutamide or abiraterone for castration-resistant prostate cancer: a multi-institution correlative biomarker study 
    Conteduca, V; Wetterskog, D; Sharabiani, M-T-A; Grande, E; Fernández-Pérez, M-P; Jayaram, A; Salvi, S; Castellano, D; Romanel, A; Lolli, C; Casadio, V; Gurioli, G; Amadori, D; Font, A; Vazquez-Estevez, S; González-del-Alba, A; Mellado, B; Fernández-Calvo, O; Méndez-Vidal, M-J; Climent, M-A; Duran, I; Gallardo, E; Rodríguez, A; Santander, C; Saez, M-I; Puente, J; Tandefelt, D-Gasi; Wingate, A; Dearnaley, D; Demichelis, F; De-Giorgi, U; González-Billalabeitia, Enrique; Attard, G (OXFORD UNIV PRESS, 2017-07)
    BACKGROUND: There is an urgent need to identify biomarkers to guide personalized therapy in castration-resistant prostate cancer (CRPC). We aimed to clinically qualify androgen receptor (AR) gene status measurement in ...
  • Disease-causing mutations in the serpin antithrombin reveal a key domain critical for inhibiting protease activities 
    Aguila, Sonia; Izaguirre, Gonzalo; Martínez-Martínez, Irene; Vicente, Vicente; Olson, Steven-T; Corral, Javier (AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2017-10-06)
    Antithrombin mainly inhibits factor Xa and thrombin. The reactive center loop (RCL) is crucial for its interactions with its protease targets and is fully inserted into the A-sheet after its cleavage, causing translocation ...
  • Significant Hypo-Responsiveness to GPVI and CLEC-2 Agonists in Pre-Term and Full-Term Neonatal Platelets and following Immune Thrombocytopenia 
    Hardy, Alexander-T; Palma-Barqueros, Verónica; Watson, Stephanie-K; Malcor, Jean-Daniel; Eble, Johannes-A; Gardiner, Elizabeth-E; Blanco-Carnero, José-Eliseo; Guijarro-Campillo, Rafael; Delgado-Marín, Juan-Luis; Lozano, María-Luisa; Teruel-Montoya, Raúl; Vicente, Vicente; Watson, Steve-P; Rivera, José; Ferrer-Marín, Francisca (GEORG THIEME VERLAG KG, 2018-06)
    Neonatal platelets are hypo-reactive to the tyrosine kinase-linked receptor agonist collagen. Here, we have investigated whether the hypo-responsiveness is related to altered levels of glycoprotein VI (GPVI) and integrin ...
  • Regulation of TFPIa expression by miR-27a/b-3p in human endothelial cells under normal conditions and in response to androgens 
    Arroyo-Rodríguez, Ana-B; Salloum-Asfar, Salam; Pérez-Sánchez, Carlos; Teruel-Montoya, Raúl; Navarro, Silvia; García-Barbera, Nuria; Luengo-Gil, Ginés; Roldán-Schilling, Vanessa; Hansen, John-Bjarne; López-Pedrera, Chary; Vicente, Vicente; González-Conejero, Rocío; Martínez, Constantino (NATURE PORTFOLIO, 2017-02-27)
    The increased risk of cardiovascular events in older men is multifactorial, but the significant reduction of testosterone levels has been involved. As this hormone regulates the expression of TFPI by unknown mechanisms, ...
  • Risk Model for Colorectal Cancer in Spanish Population Using Environmental and Genetic Factors: Results from the MCC-Spain study 
    Ibañez-Sanz, Gemma; Diez-Villanueva, Anna; Henar-Alonso, M; Rodríguez-Moranta, Francisco; Pérez-Gómez, Beatriz; Bustamante, Mariona; Martín, Vicente; Llorca, Javier; Amiano, Pilar; Ardanaz, Eva; Tardon, Adonina; Jiménez-Moleon, José-Juan; Peiro, Rosana; Alguacil, Juan; Navarro, Carmen; Guino, Elisabet; Binefa, Gemma; Fernández-Navarro, Pablo; Espinosa, Anna; Davila-Batista, Verónica; Molina, Antonio-José; Palazuelos, Camilo; Castaño-Vinyals, Gemma; Aragonés, Nuria; Kogevinas, Manolis; Pollan, Marina; Moreno, Víctor (NATURE PORTFOLIO, 2017-02-24)
    Colorectal cancer (CRC) screening of the average risk population is only indicated according to age. We aim to elaborate a model to stratify the risk of CRC by incorporating environmental data and single nucleotide ...
  • Does von Willebrand factor improve the predictive ability of current risk stratification scores in patients with atrial fibrillation? 
    García-Fernández, Amaya; Roldán-Schilling, Vanessa; Rivera-Caravaca, José-Miguel; Hernández-Romero, Diana; Valdés-Chavarri, Mariano; Vicente, Vicente; Lip, Gregory-Y-H; Marín, Francisco (NATURE PORTFOLIO, 2017-01-30)
    Von Willebrand factor (vWF) is a biomarker of endothelial dysfunction. We investigated its role on prognosis in anticoagulated atrial fibrillation (AF) patients and determined whether its addition to clinical risk ...
  • Molecular regionalization of the developing amphioxus neural tube challenges major partitions of the vertebrate brain 
    Albuixech-Crespo, Beatriz; López-Blanch, Laura; Burguera, Demian; Maeso, Ignacio; Sánchez-Arrones, Luisa; Moreno-Bravo, Juan-Antonio; Somorjai, Ildiko; Pascual-Anaya, Juan; Puelles, Eduardo; Bovolenta, Paola; García-Fernández, Jordi; Puelles, Luis; Irimia, Manuel; Ferran, José-Luis (PUBLIC LIBRARY SCIENCE, 2017-04)
    All vertebrate brains develop following a common Bauplan defined by anteroposterior (AP) and dorsoventral (DV) subdivisions, characterized by largely conserved differential expression of gene markers. However, it is still ...
  • Radial glia fibers translate Fgf8 morphogenetic signals to generate a thalamic nuclear complex protomap in the mantle layer 
    Botella-López, Arancha; García-López, Raquel; Pombero, Ana; Martínez, Salvador (SPRINGER HEIDELBERG, 2019-03)
    Thalamic neurons are distributed between different nuclear groups of the thalamic multinuclear complex; they develop topologically ordered specific projections that convey information on voluntary motor programs and sensory ...
  • Nuclear derivatives and axonal projections originating from rhombomere 4 in the mouse hindbrain 
    Di-Bonito, María; Studer, Michele; Puelles, Luis (SPRINGER HEIDELBERG, 2017-11)
    The r4-derived territory is located in the pontine region of the brainstem, forming a wedge-shaped slice that broadens from the choroidal roof to the ventral midline. R4-derived neuronal populations migrate radially inside ...
  • Galectin-3 as a marker of interstitial atrial remodelling involved in atrial fibrillation 
    Hernández-Romero, Diana; Vílchez, Juan-Antonio; Lahoz, Alvaro; Romero-Aniorte, Ana-I; Jover, Eva; García-Alberola, Arcadio; Jara-Rubio, Rubén; Martínez, Carlos-M; Valdés-Chavarri, Mariano; Marín, Francisco (NATURE PORTFOLIO, 2017-01-12)
    Remodelling in the atria could appear as a result of hypertension, diabetes or ischaemic heart disease. Galectin-3 (Gal-3) is a mediator of profibrotic pathways and a potential biomarker of cardiac remodelling. We prospectively ...
  • Sequence data and association statistics from 12,940 type 2 diabetes cases and controls (vol 4, 170179, 2017) 
    Flannick, Jason; Fuchsberger, Christian; Mahajan, Anubha; Teslovich, Tanya-M; Agarwala, Vineeta; Gaulton, Kyle-J; Caulkins, Lizz; Koesterer, Ryan; Ma, Clement; Moutsianas, Loukas; McCarthy, Davis-J; Rivas, Manuel-A; Perry, John-R-B; Sim, Xueling; Blackwell, Thomas-W; Robertson, Neil-R; Rayner, N-William; Cingolani, Pablo; Locke, Adam-E; Tajes, Juan-Fernández; Highland, Heather-M; Dupuis, Josee; Chines, Peter-S; Lindgren, Cecilia-M; Hartl, Christopher; Jackson, Anne-U; Chen, Han; Huyghe, Jeroen-R; van-de-Bunt, Martijn; Pearson, Richard-D; Kumar, Ashish; Mueller-Nurasyid, Martina; Grarup, Niels; Stringham, Heather-M; Gamazon, Eric-R; Lee, Jaehoon; Chen, Yuhui; Scott, Robert-A; Below, Jennifer-E; Chen, Peng; Huang, Jinyan; Go, Min-Jin; Stitzel, Michael-L; Pasko, Dorota; Parker, Stephen-C-J; Varga, Tibor-V; Green, Todd; Beer, Nicola-L; Day-Williams, Aaron-G; Ferreira, Teresa; Fingerlin, Tasha; Horikoshi, Momoko; Hu, Cheng; Huh, Iksoo; Ikram, Mohammad-Kamran; Kim, Bong-Jo; Kim, Yongkang; Kim, Young-Jin; Kwon, Min-Seok; Lee, Juyoung; Lee, Selyeong; Lin, Keng-Han; Maxwell, Taylor-J; Nagai, Yoshihiko; Wang, Xu; Welch, Ryan-P; Yoon, Joon; Zhang, Weihua; Barzilai, Nir; Voight, Benjamín-F; Han, Bok-Ghee; Jenkinson, Christopher-P; Kuulasmaa, Teemu; Kuusisto, Johanna; Manning, Alisa; Ng, Maggie-C-Y; Palmer, Nicholette-D; Balkau, Beverley; Stancakova, Alena; Abboud, Hanna-E; Boeing, Heiner; Giedraitis, Vilmantas; Prabhakaran, Dorairaj; Gottesman, Omri; Scott, James; Carey, Jason; Kwan, Phoenix; Grant, George; Smith, Joshua-D; Neale, Benjamín-M; Purcell, Shaun; Butterworth, Adam-S; Howson, Joanna-M-M; Lee, Heung-Man; Lu, Yingchang; Kwak, Soo-Heon; Zhao, Wei; Danesh, John; Lam, Vincent-K-L; Park, Kyong-Soo; Saleheen, Danish; So, Wing-Yee; Tam, Claudia-H-T; Afzal, Uzma; Aguilar, David; Arya, Rector; Aung, Tin; Chan, Edmund; Navarro, Carmen; Cheng, Ching-Yu; Palli, Domenico; Correa, Adolfo; Curran, Joanne-E; Rybin, Dennis; Farook, Vidya-S; Fowler, Sharon-P; Freedman, Barry-I; Griswold, Michael; Hale, Daniel-Esten; Hicks, Pamela-J; Khor, Chiea-Chuen; Kumar, Satish; Lehne, Benjamín; Thuillier, Dorothee; Lim, Wei-Yen; Liu, Jianjun; Loh, Marie; Musani, Solomon-K; Puppala, Sobha; Scott, William-R; Yengo, Loic; Tan, Sian-Tsung; Taylor, Herman-A; Thameem, Farook; Wilson, Gregory; Wong, Tien-Yin; Njolstad, Pal-Rasmus; Levy, Jonathan-C; Mangino, Massimo; Bonnycastle, Lori-L; Schwarzmayr, Thomas; Fadista, Joao; Surdulescu, Gabriela-L; Herder, Christian; Groves, Christopher-J; Wieland, Thomas; Bork-Jensen, Jette; Brandslund, Ivan; Christensen, Cramer; Koistinen, Heikki-A; Doney, Alex-S-F; Kinnunen, Leena; Esko, Tonu; Farmer, Andrew-J; Hakaste, Liisa; Hodgkiss, Dylan; Kravic, Jasmina; Lyssenko, Valeriya; Hollensted, Mette; Jorgensen, Marit-E; Jorgensen, Torben; Ladenvall, Claes; Justesen, Johanne-Marie; Karajamaki, Annemari; Kriebel, Jennifer; Rathmann, Wolfgang; Lannfelt, Lars; Lauritzen, Torsten; Narisu, Narisu; Linneberg, Allan; Melander, Olle; Milani, Lili; Neville, Matt; Orho-Melander, Marju; Qi, Lu; Qi, Qibin; Roden, Michael; Rolandsson, Olov; Swift, Amy; Rosengren, Anders-H; Stirrups, Kathleen; Wood, Andrew-R; Mihailov, Evelin; Blancher, Christine; Carneiro, Mauricio-O; Maguire, Jared; Poplin, Ryan; Shakir, Khalid; Fennell, Timothy; DePristo, Mark; de-Ángelis, Martin-Hrabe; Deloukas, Panos; Gjesing, Anette-P; Jun, Goo; Nilsson, Peter-M; Murphy, Jacquelyn; Onofrio, Robert; Thorand, Barbara; Hansen, Torben; Meisinger, Christa; Hu, Frank-B; Isomaa, Bo; Karpe, Fredrik; Liang, Liming; Peters, Annette; Huth, Cornelia; O'Rahilly, Stephen-P; Palmer, Colin-N-A; Pedersen, Oluf; Rauramaa, Rainer; Tuomilehto, Jaakko; Salomaa, Veikko; Watanabe, Richard-M; Syvanen, Ann-Christine; Bergman, Richard-N; Bharadwaj, Dwaipayan; Bottinger, Erwin-P; Cho, Yoon-Shin; Chandak, Giriraj-R; Chan, Juliana-Cn; Chia, Kee-Seng; Daly, Mark-J; Ebrahim, Shah-B; Langenberg, Claudia; Elliott, Paul; Jablonski, Kathleen-A; Lehman, Donna-M; Jia, Weiping; Ma, Ronald-C-W; Pollin, Toni-I; Sandhu, Manjinder; Tandon, Nikhil; Froguel, Philippe; Barroso, Inés; Teo, Yik-Ying; Zeggini, Eleftheria; Loos, Ruth-J-F; Small, Kerrin-S; Ried, Janina-S; DeFronzo, Ralph-A; Grallert, Harald; Glaser, Benjamín; Metspalu, Andrés; Wareham, Nicholas-J; Walker, Mark; Banks, Eric; Gieger, Christian; Ingelsson, Erik; Im, Hae-Kyung; Illig, Thomas; Franks, Paul-W; Buck, Gemma; Trakalo, Joseph; Buck, David; Prokopenko, Inga; Magi, Reedik; Lind, Lars; Farjoun, Yossi; Owen, Katharine-R; Gloyn, Anna-L; Strauch, Konstantin; Tuomi, Tiinamaija; Kooner, Jaspal-Singh; Lee, Jong-Young; Park, Taesung; Donnelly, Peter; Morris, Andrew-D; Hattersley, Andrew-T; Bowden, Donald-W; Collins, Francis-S; Atzmon, Gil; Chambers, John-C; Spector, Timothy-D; Laakso, Markku; Strom, Tim-M; Bell, Graeme-I; Blangero, John; Duggirala, Ravindranath; Tai, EShyong; McVean, Gilean; Hanis, Craig-L; Wilson, James-G; Seielstad, Mark; Frayling, Timothy-M; Meigs, James-B; Cox, Nancy-J; Sladek, Rob; Lander, Eric-S; Gabriel, Stacey; Mohlke, Karen-L; Meitinger, Thomas; Groop, Leif; Abecasis, Goncalo; Scott, Laura-J; Morris, Andrew-P; Kang, Hyun-Min; Altshuler, David; Burtt, Noel-P; Florez, José-C; Boehnke, Michael; McCarthy, Mark-I (NATURE PUBLISHING GROUP, 2018-01-23)
    This corrects the article DOI: 10.1038/sdata.2017.179.
  • Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls 
    Flannick, Jason; Fuchsberger, Christian; Mahajan, Anubha; Teslovich, Tanya-M; Agarwala, Vineeta; Gaulton, Kyle-J; Caulkins, Lizz; Koesterer, Ryan; Ma, Clement; Moutsianas, Loukas; McCarthy, Davis-J; Rivas, Manuel-A; Perry, John-R-B; Sim, Xueling; Blackwell, Thomas-W; Robertson, Neil-R; Rayner, N-William; Cingolani, Pablo; Locke, Adam-E; Tajes, Juan-Fernández; Highland, Heather-M; Dupuis, Josee; Chines, Peter-S; Lindgren, Cecilia-M; Hartl, Christopher; Jackson, Anne-U; Chen, Han; Huyghe, Jeroen-R; De-Bunt, Martijn-Van; Pearson, Richard-D; Kumar, Ashish; Muller-Nurasyid, Martina; Grarup, Niels; Stringham, Heather-M; Gamazon, Eric-R; Lee, Jaehoon; Chen, Yuhui; Scott, Robert-A; Below, Jennifer-E; Chen, Peng; Huang, Jinyan; Go, Min-Jin; Stitzel, Michael-L; Pasko, Dorota; Parker, Stephen-C-J; Varga, Tibor-V; Green, Todd; Beer, Nicola-L; Day-Williams, Aaron-G; Ferreira, Teresa; Fingerlin, Tasha; Horikoshi, Momoko; Hu, Cheng; Huh, Iksoo; Ikram, Mohammad-Kamran; Kim, Bong-Jo; Kim, Yongkang; Kim, Young-Jin; Kwon, Min-Seok; Lee, Juyoung; Lee, Selyeong; Lin, Keng-Han; Maxwell, Taylor-J; Nagai, Yoshihiko; Wang, Xu; Welch, Ryan-P; Yoon, Joon; Zhang, Weihua; Barzilai, Nir; Voight, Benjamín-F; Han, Bok-Ghee; Jenkinson, Christopher-P; Kuulasmaa, Teemu; Kuusisto, Johanna; Manning, Alisa; Ng, Maggie-C-Y; Palmer, Nicholette-D; Balkau, Beverley; Stancakova, Alena; Abboud, Hanna-E; Boeing, Heiner; Giedraitis, Vilmantas; Prabhakaran, Dorairaj; Gottesman, Omri; Scott, James; Carey, Jason; Kwan, Phoenix; Grant, George; Smith, Joshua-D; Neale, Benjamín-M; Purcell, Shaun; Butterworth, Adam-S; Howson, Joanna-M-M; Lee, Heung-Man; Lu, Yingchang; Kwak, Soo-Heon; Zhao, Wei; Danesh, John; Lam, Vincent-K-L; Park, Kyong-Soo; Saleheen, Danish; So, Wing-Yee; Tam, Claudia-H-T; Afzal, Uzma; Aguilar, David; Arya, Rector; Aung, Tin; Chan, Edmund; Navarro, Carmen; Cheng, Ching-Yu; Palli, Domenico; Correa, Adolfo; Curran, Joanne-E; Rybin, Dennis; Farook, Vidya-S; Fowler, Sharon-P; Freedman, Barry-I; Griswold, Michael; Hale, Daniel-Esten; Hicks, Pamela-J; Khor, Chiea-Chuen; Kumar, Satish; Lehne, Benjamín; Thuillier, Dorothee; Lim, Wei-Yen; Liu, Jianjun; Loh, Marie; Musani, Solomon-K; Puppala, Sobha; Scott, William-R; Yengo, Loic; Tan, Sian-Tsung; Taylor, Herman-A; Thameem, Farook; Wilson, Gregory; Wong, Tien-Yin; Njolstad, Pal-Rasmus; Levy, Jonathan-C; Mangino, Massimo; Bonnycastle, Lori-L; Schwarzmayr, Thomas; Fadista, Joao; Surdulescu, Gabriela-L; Herder, Christian; Groves, Christopher-J; Wieland, Thomas; Bork-Jensen, Jette; Brandslund, Ivan; Christensen, Cramer; Koistinen, Heikki-A; Doney, Alex-S-F; Kinnunen, Leena; Esko, Tonu; Farmer, Andrew-J; Hakaste, Liisa; Hodgkiss, Dylan; Kravic, Jasmina; Lyssenko, Valeriya; Hollensted, Mette; Jorgensen, Marit-E; Jorgensen, Torben; Ladenvall, Claes; Justesen, Johanne-Marie; Karajamaki, Annemari; Kriebel, Jennifer; Rathmann, Wolfgang; Lannfelt, Lars; Lauritzen, Torsten; Narisu, Narisu; Linneberg, Allan; Melander, Olle; Milani, Lili; Neville, Matt; Orho-Melander, Marju; Qi, Lu; Qi, Qibin; Roden, Michael; Rolandsson, Olov; Swift, Amy; Rosengren, Anders-H; Stirrups, Kathleen; Wood, Andrew-R; Mihailov, Evelin; Blancher, Christine; Carneiro, Mauricio-O; Maguire, Jared; Poplin, Ryan; Shakir, Khalid; Fennell, Timothy; DePristo, Mark; De-Ángelis, Martin-Hrabe; Deloukas, Panos; Gjesing, Anette-P; Jun, Goo; Nilsson, Peter-M; Murphy, Jacquelyn; Onofrio, Robert; Thorand, Barbara; Hansen, Torben; Meisinger, Christa; Hu, Frank-B; Isomaa, Bo; Karpe, Fredrik; Liang, Liming; Peters, Annette; Huth, Cornelia; O'Rahilly, Stephen-P; Palmer, Colin-N-A; Pedersen, Oluf; Rauramaa, Rainer; Tuomilehto, Jaakko; Salomaa, Veikko; Watanabe, Richard-M; Syvanen, Ann-Christine; Bergman, Richard-N; Bharadwaj, Dwaipayan; Bottinger, Erwin-P; Cho, Yoon-Shin; Chandak, Giriraj-R; Chan, Juliana-Cn; Chia, Kee-Seng; Daly, Mark-J; Ebrahim, Shah-B; Langenberg, Claudia; Elliott, Paul; Jablonski, Kathleen-A; Lehman, Donna-M; Jia, Weiping; Ma, Ronald-Cw; Pollin, Toni-I; Sandhu, Manjinder; Tandon, Nikhil; Froguel, Philippe; Barroso, Inés; Teo, Yik-Ying; Zeggini, Eleftheria; Loos, Ruth-J-F; Small, Kerrin-S; Ried, Janina-S; DeFronzo, Ralph-A; Grallert, Harald; Glaser, Benjamín; Metspalu, Andrés; Wareham, Nicholas-J; Walker, Mark; Banks, Eric; Gieger, Christian; Ingelsson, Erik; Im, Hae-Kyung; Illig, Thomas; Franks, Paul-W; Buck, Gemma; Trakalo, Joseph; Buck, David; Prokopenko, Inga; Magi, Reedik; Lind, Lars; Farjoun, Yossi; Owen, Katharine-R; Gloyn, Anna-L; Strauch, Konstantin; Tuomi, Tiinamaija; Kooner, Jaspal-Singh; Lee, Jong-Young; Park, Taesung; Donnelly, Peter; Morris, Andrew-D; Hattersley, Andrew-T; Bowden, Donald-W; Collins, Francis-S; Atzmon, Gil; Chambers, John-C; Spector, Timothy-D; Laakso, Markku; Strom, Tim-M; Bell, Graeme-I; Blangero, John; Duggirala, Ravindranath; Tai, EShyong; McVean, Gilean; Hanis, Craig-L; Wilson, James-G; Seielstad, Mark; Frayling, Timothy-M; Meigs, James-B; Cox, Nancy-J; Sladek, Rob; Lander, Eric-S; Gabriel, Stacey; Mohlke, Karen-L; Meitinger, Thomas; Groop, Leif; Abecasis, Goncalo; Scott, Laura-J; Morris, Andrew-P; Kang, Hyun-Min; Altshuler, David; Burtt, Noel-P; Florez, José-C; Boehnke, Michael; McCarthy, Mark-I (NATURE PORTFOLIO, 2017-12-19)
    To investigate the genetic basis of type 2 diabetes (T2D) to high resolution, the GoT2D and T2D-GENES consortia catalogued variation from whole-genome sequencing of 2,657 European individuals and exome sequencing of 12,940 ...
  • Non-proliferative neurogenesis in human periodontal ligament stem cells 
    Bueno, Carlos; Martínez-Morga, Marta; Martínez, Salvador (NATURE PORTFOLIO, 2019-12-02)
    Understanding the sequence of events from undifferentiated stem cells to neuron is not only important for the basic knowledge of stem cell biology, but also for therapeutic applications. In this study we examined the ...

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