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Envíos recientes

03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla): Envíos recientes

  • Early Events in Retinal Degeneration Caused by Rhodopsin Mutation or Pigment Epithelium Malfunction: Differences and Similarities 
    Di-Pierdomenico, Johnny; García-Ayuso, Diego; Pinilla, Isabel; Cuenca, Nicolas; Vidal-Sanz, Manuel; Agudo-Barriuso, Marta; Villegas-Pérez, María-Paz (FRONTIERS MEDIA SA, 2017-03-06)
    To study the course of photoreceptor cell death and macro and microglial reactivity in two rat models of retinal degeneration with different etiologies. Retinas from P23H-1 (rhodopsin mutation) and Royal College of Surgeon ...
  • Helicobacter pylori Antibody Reactivities and Colorectal Cancer Risk in a Case-control Study in Spain 
    Fernández-de-Larrea-Baz, Nerea; Michel, Ángelika; Romero, Beatriz; Pérez-Gómez, Beatriz; Moreno, Víctor; Martín, Vicente; Dierssen-Sotos, Trinidad; Jiménez-Moleon, José-Juan; Castilla, Jesús; Tardon, Adonina; Ruiz, Irune; Peiro, Rosana; Tejada, Antonio; Chirlaque-López, María-Dolores; Butt, Julia-A; Olmedo-Requena, Rocío; Gómez-Acebo, Inés; Linares, Pedro; Boldo, Elena; Castells, Antoni; Pawlita, Michael; Castaño-Vinyals, Gemma; Kogevinas, Manolis; de-Sanjose, Silvia; Pollan, Marina; del-Campo, Rosa; Waterboer, Tim; Aragonés, Nuria (FRONTIERS MEDIA SA, 2017-05-29)
    Background: Several studies have suggested that Helicobacter pylori (H. pylori) infection is a risk factor for colorectal cancer (CRC), while others have not confirmed this hypothesis. This work aimed to assess the relation ...
  • P2X7 receptor induces Tumor necrosis Factor-a converting enzyme activation and release to Boost TnF-ae Production 
    Barberá-Cremades, María; Gómez, Ana-I; Baroja-Mazo, Alberto; Martínez-Alarcón, Laura; Martínez, Carlos-M; de-Torre-Minguela, Carlos; Pelegrín, Pablo (FRONTIERS MEDIA SA, 2017-07-24)
    Tumor necrosis factor (TNF)-? is a major pro-inflammatory cytokine produced in response to toll-like receptor stimulation. TNF-? release is controlled by the activity of TNF-? converting enzyme (TACE) that cut membrane-bound ...
  • Zebra Fish Lacking Adaptive immunity Acquire an Antiviral Alert State Characterized by Upregulated Gene expression of Apoptosis, Multigene Families, and interferon-related Genes (vol 8, pg 121, 2017) 
    García-Valtanen, Pablo; Martínez-López, Alicia; López-Muñoz, Azucena; Bello-Pérez, Melissa; Medina-Gali, Regla-M; Ortega-Villaizan, María-del-Mar; Varela, Mónica; Figueras, Antonio; Mulero, Victoriano; Novoa, Beatriz; Estepa, Amparo; Coll, Julio (FRONTIERS MEDIA SA, 2017-06-13)
    [This corrects the article on p. 121 in vol. 8, PMID: 28243233.].
  • Zebra Fish Lacking Adaptive Immunity Acquire an Antiviral Alert State Characterized by Upregulated Gene Expression of Apoptosis, Multigene Families, and Interferon-Related Genes 
    García-Valtanen, Pablo; Martínez-López, Alicia; López-Muñoz, Azucena; Bello-Pérez, Melissa; Medina-Gali, Regla-M; Ortega-Villaizan, María-del-Mar; Varela, Mónica; Figueras, Antonio; Mulero, Victoriano; Novoa, Beatriz; Estepa, Amparo; Coll, Julio (FRONTIERS MEDIA SA, 2017-02-13)
    To investigate fish innate immunity, we have conducted organ and cell immune-related transcriptomic as well as immunohistologic analysis in mutant zebra fish (Danio rerio) lacking adaptive immunity (rag1(-/-)) at different ...
  • Liver transplantation as a rescue surgery after failure of embolization of a giant hepatic artery pseudoaneurysm 
    Ferreras, David; López-López, Víctor; Robles-Campos, Ricardo; Sánchez-Bueno, Francisco; Ramírez, Pablo (ARAN EDICIONES, S A, 2019)
    We present the case of a male diagnosed with a giant hepatic artery aneurysm, which first presented with pain and hemorrhage due to a partial rupture of the aneurysm. After discarding treatment with a stent or surgery due ...
  • Protecting renal function: a relevant decision for liver transplantation 
    Pons-Miñano, José-Antonio (ARAN EDICIONES, S A, 2018)
    Advances in surgical technique, as well as in medical management and immunosuppression (IS), have represented a significant improvement in the survival of patients undergoing liver transplantation (LT), with 1-year, 5-year, ...
  • Bleeding risk in endoscopic retrograde cholangiopancreatography. Impact of the use of antithrombotic drugs 
    Alberca-de-las-Parras, Fernando; Egea-Valenzuela, Juan; Carballo-Álvarez, Fernando (ARAN EDICIONES, S A, 2017)
    AIMS: To analyze the risk factors for hemorrhage during endoscopic retrograde cholangiopancreatography and the impact of antithrombotic drugs. MATERIAL AND METHODS: Data sources: papers indexed in PubMed have been reviewed, ...
  • Evaluation of rat liver with ARFI elastography: In vivo and ex vivo study 
    Carbonell, Guillermo; Berna-Serna, Juan-de-Dios; Oltra, Lidia; Martínez, Carlos-M; García-Carrillo, Nuria; Guzmán-Aroca, Florentina; Salazar, Francisco-Javier; Tudela, José; Berna-Mestre, Juan-de-Dios (PUBLIC LIBRARY SCIENCE, 2019-05-23)
    OBJECTIVE: The aim of this study was to compare in vivo vs ex vivo liver stiffness in rats with acoustic radiation force impulse (ARFI) elastography using the histological findings as the gold standard. METHODS: Eighteen ...
  • Conservatively managed patients with non-ST-segment elevation acute coronary syndrome are undertreated with indicated medicines 
    Candela, Elena; Marín, Francisco; Rivera-Caravaca, José-Miguel; Vicente-Ibarra, Nuria; Carrillo, Luna; Esteve-Pastor, María-Asunción; Lozano, Teresa; Jesus-Macias, Manuel; Pernias, Vicente; Sandin, Miriam; Orenes-Piñero, Esteban; Quintana-Giner, Miriam; Hortelano, Ignacio; Villamia, Beatriz; Veliz, Andrea; Valdés-Chavarri, Mariano; Martínez-Martínez, Juan-G; Ruiz-Nodar, Juan-M (PUBLIC LIBRARY SCIENCE, 2018-11-28)
    INTRODUCTION AND AIMS: Patients with non-ST-elevation acute coronary syndrome (NSTE-ACS) are often managed conservatively. Clinical practice guidelines recommend treating these patients with the same pharmacological drugs ...
  • Obligation and negative consequences in primary caregivers of dependent older relatives 
    del-Pino-Casado, Rafael; López-Martínez, Catalina; Serrano-Ortega, Natalia; Pastor-Bravo, María-del-Mar; Parra-Anguita, Laura (PUBLIC LIBRARY SCIENCE, 2018-09-07)
    The purpose of this study was to analyse the multidimensional nature of obligation and the relations between each dimension of obligation and both anxiety and depression. A secondary analysis of data from two cross-sectional ...
  • miR-146a deficiency in hematopoietic cells is not involved in the development of atherosclerosis 
    del-Monte, Alberto; Arroyo-Rodríguez, Ana-B; Andrés-Manzano, María-J; García-Barbera, Nuria; Caleprico, María-S; Vicente, Vicente; Roldán-Schilling, Vanessa; González-Conejero, Rocío; Martínez, Constantino; Andrés, Vicente (PUBLIC LIBRARY SCIENCE, 2018-06-14)
    BACKGROUND: Atherosclerosis involves activation of the IRAK1/TRAF6/NF-?B inflammatory cascade, which is negatively regulated by miR146a. Previous studies showed that the TT genotype of rs2431697, located near the miR-146a ...
  • Comprehensive comparison of neonate and adult human platelet transcriptomes 
    Caparros-Pérez, Eva; Teruel-Montoya, Raúl; López-Andreo, María-José; Carmen-Llanos, Ma; Rivera, José; Palma-Barqueros, Verónica; Blanco-Carnero, José-Eliseo; Vicente, Vicente; Martínez, Constantino; Ferrer-Marín, Francisca (PUBLIC LIBRARY SCIENCE, 2017-08-16)
    Understanding the underlying mechanisms of the well-substantiated platelet hyporeactivity in neonates is of interest given their implications for the clinical management of newborns, a population at higher bleeding risk ...
  • Physical activity domains and risk of gastric adenocarcinoma in the MCC-Spain case-control study 
    Huerta-Castaño, José-María; Chirlaque-López, María-Dolores; Molina, Antonio-J; Amiano, Pilar; Martín, Vicente; Fernández-Villa, Tania; Pérez-Gómez, Beatriz; Moreno, Víctor; Burgui, Rosana; Gómez-Acebo, Inés; Ramos-Lora, Manuel; Fernández-Tardon, Guillermo; Peiro, Rosana; Olmedo-Requena, Rocío; Pollan, Marina; Kogevinas, Manolis; Castaño-Vinyals, Gemma; Aragonés, Nuria; Navarro, (PUBLIC LIBRARY SCIENCE, 2017-07-06)
    BACKGROUND: Evidence for a protective role of physical activity against development of stomach cancer is yet inconclusive. We studied the association of domain-specific physical activity and the risk of gastric adenocarcinoma ...
  • Characterization and mutational analysis of a nicotinamide mononucleotide deamidase from Agrobacterium tumefaciens showing high thermal stability and catalytic efficiency 
    Martínez-Moñino, Ana-Belén; Zapata-Pérez, Rubén; García-Saura, Antonio-Ginés; Gil-Ortiz, Fernando; Pérez-Gilabert, Manuela; Sánchez-Ferrer, Álvaro (PUBLIC LIBRARY SCIENCE, 2017-04-07)
    NAD+ has emerged as a crucial element in both bioenergetic and signaling pathways since it acts as a key regulator of cellular and organismal homeostasis. Among the enzymes involved in its recycling, nicotinamide mononucleotide ...
  • Mapping the association between back pain and type 2 diabetes: A cross-sectional and longitudinal study of adult Spanish twins 
    Dario, Amabile; Ferreiraz, Manuela; Refshauge, Kathryn; Harmer, Alison; Sánchez-Romera, Juan-F; Pérez-Riquelme, Francisco; Cisneros, Ligia; Ordoñana, Juan-Ramón; Ferreira, Paulo (PUBLIC LIBRARY SCIENCE, 2017-04-03)
    BACKGROUND: Back pain and type 2 diabetes often co-occur, resulting in greater impact on people's health and complexity in their care. Plausible causal mechanisms for this association have been proposed, yet the nature of ...
  • Nutritional quality of food as represented by the FSAm-NPS nutrient profiling system underlying the Nutri-Score label and cancer risk in Europe: Results from the EPIC prospective cohort study 
    Deschasaux, Melanie; Huybrechts, Inge; Murphy, Neil; Julia, Chantal; Hercberg, Serge; Srour, Bernard; Kesse-Guyot, Emmanuelle; Latino-Martel, Paule; Biessy, Carine; Casagrande, Corinne; Jenab, Mazda; Ward, Heather; Weiderpass, Elisabete; Dahm, Christina-C; Overvad, Kim; Kyro, Cecilie; Olsen, Anja; Affret, Aurelie; Boutron-Ruault, Marie-Christine; Mahamat-Saleh, Yahya; Kaaks, Rudolf; Kuehn, Tilman; Boeing, Heiner; Schwingshackl, Lukas; Bamia, Christina; Peppa, Eleni; Trichopoulou, Antonia; Masala, Giovanna; Krogh, Vittorio; Panico, Salvatore; Tumino, Rosario; Sacerdote, Carlotta; Bueno-de-Mesquita, Bas; Peeters, Petra-H; Hjartaker, Anette; Rylander, Charlotta; Skeie, Guri; Quirós, José-Ramón; Jakszyn, Paula; Salamanca-Fernández, Elena; Huerta-Castaño, José-María; Ardanaz, Eva; Amiano, Pilar; Ericson, Ulrika; Sonestedt, Emily; Huseinovic, Ena; Johansson, Ingegerd; Khaw, Kay-Tee; Wareham, Nick; Bradbury, Kathryn-E; Pérez-Cornago, Aurora; Tsilidis, Konstantinos-K; Ferrari, Pietro; Riboli, Elio; Gunter, Marc-J; Touvier, Mathilde (PUBLIC LIBRARY SCIENCE, 2018-09)
    BACKGROUND: Helping consumers make healthier food choices is a key issue for the prevention of cancer and other diseases. In many countries, political authorities are considering the implementation of a simplified labelling ...
  • Effect of Porcine circovirus 2 (PCV-2) maternally derived antibodies on performance and PCV-2 viremia in vaccinated piglets under field conditions 
    Figueras-Gourgues, S; Fraile, L; Segales, J; Hernández-Caravaca, I; López-Úbeda, Rebeca; García-Vazquez, F-A; Gómez-Duran, O; Grosse-Liesner, B (BMC, 2019-09-05)
    BACKGROUND: Nowadays, the most common presentation of PCV-2 is the subclinical infection in piglets after weaning. The success of PCV-2 vaccination is associated with the control of the clinical disease as well as the ...
  • Analysis and visualization of disease courses in a semantically-enabled cancer registry 
    Esteban-Gil, Ángel; Fernández-Breis, Jesualdo-Tomás; Boeker, Martin (BMC, 2017-09-29)
    BACKGROUND: Regional and epidemiological cancer registries are important for cancer research and the quality management of cancer treatment. Many technological solutions are available to collect and analyse data for cancer ...
  • Does the sex of one's co-twin affect height and BMI in adulthood? A study of dizygotic adult twins from 31 cohorts 
    Bogl, Leonie-H; Jelenkovic, Aline; Vuoksimaa, Eero; Ahrenfeldt, Linda; Pietilainen, Kirsi-H; Stazi, María-A; Fagnani, Corrado; D'Ippolito, Cristina; Hur, Yoon-Mi; Jeong, Hoe-Uk; Silberg, Judy-L; Eaves, Lindon-J; Maes, Hermine-H; Bayasgalan, Gombojav; Narandalai, Danshiitsoodol; Cutler, Tessa-L; Kandler, Christian; Jang, Kerry-L; Christensen, Kaare; Skytthe, Axel; Kyvik, Kirsten-O; Cozen, Wendy; Hwang, Amie-E; Mack, Thomas-M; Derom, Catherine-A; Vlietinck, Robert-F; Nelson, Tracy-L; Whitfield, Keith-E; Corley, Robin-P; Huibregtse, Brooke-M; McAdams, Tom-A; Eley, Thalia-C; Gregory, Alice-M; Krueger, Robert-F; Mcgue, Matt; Pahlen, Shandell; Willemsen, Gonneke; Bartels, Meike; van-Beijsterveldt, Toos-C-E-M; Pang, Zengchang; Tan, Qihua; Zhang, Dongfeng; Martin, Nicholas-G; Medland, Sarah-E; Montgomery, Grant-W; Hjelmborg, Jacob-van-B; Rebato, Esther; Swan, Gary-E; Krasnow, Ruth; Busjahn, Andreas; Lichtenstein, Paul; Oncel, Sevgi-Y; Aliev, Fazil; Baker, Laura-A; Tuvblad, Catherine; Siribaddana, Sisira-H; Hotopf, Matthew; Sumathipala, Athula; Rijsdijk, Fruhling; Magnusson, Patrik-K-E; Pedersen, Nancy-L; Aslan, Anna-K-Dahl; Ordoñana, Juan-Ramón; Sánchez-Romera, Juan-F; Colodro-Conde, Lucía; Duncan, Glen-E; Buchwald, Dedra; Tarnoki, Adam-D; Tarnoki, David-L; Yokoyama, Yoshie; Hopper, John-L; Loos, Ruth-J-F; Boomsma, Dorret-I; Sorensen, Thorkild-I-A; Silventoinen, Karri; Kaprio, Jaakko (BMC, 2017-04-27)
    BACKGROUND: The comparison of traits in twins from opposite-sex (OS) and same-sex (SS) dizygotic twin pairs is considered a proxy measure of prenatal hormone exposure. To examine possible prenatal hormonal influences on ...

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