Repositorio Dspace

Envíos recientes

03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla): Envíos recientes

  • Aging and trace elements in human coronal tooth dentine 
    Fernández-Escudero, Ana-C; Legaz, Isabel; Prieto-Bonete, Gemma; López-Nicolas, Manuel; Maurandi-López, Antonio; Pérez-Cárceles, María-D (NATURE PORTFOLIO, 2020-06-19)
    Teeth are a fundamental tool in forensic odontology for identification in a legal context of those individuals who cannot be identified visually or by other means. Dentine presents physiological exchanges of in trace ...
  • Recommendations for vaccination in patients with multiple sclerosis who are eligible for immunosuppressive therapies: Spanish consensus statement 
    Otero-Romero, S; Rodríguez-García, J; Vilella, A; Ara, J-R; Brieva, L; Calles, C; Carmona, O; Casanova, V; Costa-Frossard, L; Eichau, S; García-Merino, J-A; García-Vidal, C; González-Platas, M; Llaneza, M; Martínez-Gines, M; Meca-Lallana, J-E; Prieto, J-M; Rodríguez-Antiguedad, A; Tintore, M; Blanco, Y; Moral, E (ELSEVIER ESPANA SLU, 2021-01)
    BACKGROUND: The recent development of highly effective treatments for multiple sclerosis (MS) and the potential risk of infectious complications require the development of prevention and risk minimisation strategies. ...
  • Volumetric study of the maxillary sinus in patients with sinus pathology 
    Pérez-Sayans, Mario; Suárez-Quintanilla, Juan-A; Chamorro-Petronacci, Cintia-M; Suárez-Penaranda, José-M; López-Jornet, Pia; Gómez-García, Francisco; Guerrero-Sánchez, Yolanda (PUBLIC LIBRARY SCIENCE, 2020)
    OBJECTIVES: The aim of this study is 1) to obtain the area and volumes of the maxillary sinuses in patients affected by clinically unilateral sinus pathology by comparing the results to the contralateral sinus and 2) to ...
  • ALG12-CDG: An unusual patient without intellectual disability and facial dysmorphism, and with a novel variant 
    de-la-Morena-Barrio, María-Eugenia; Sabater-Molina, María; de-la-Morena-Barrio, Belén; Ruhaak, Renee-L; Minano, Antonia; Padilla, José; Toderici, Mara; Roldán, Vanessa; Gimeno, Juan-R; Vicente, Vicente; Corral, Javier (WILEY, 2020-08)
    BACKGROUND: Congenital disorder of glycosylation (CDG) type I is a group of rare disorders caused by recessive mutations in up to 25 genes that impair the N-glycan precursor formation and its transfer to proteins resulting ...
  • Pseudozyma Priming Influences Expression of Genes Involved in Metabolic Pathways and Immunity in Zebrafish Larvae 
    Siriyappagouder, Prabhugouda; Galindo-Villegas, Jorge; Dhanasiri, Anusha-K-S; Zhang, Qirui; Mulero, Victoriano; Kiron, Viswanath; Fernandes, Jorge-M-O (FRONTIERS MEDIA SA, 2020-05-22)
    Fungi, particularly yeasts, are known essential components of the host microbiota but their functional relevance in development of immunity and physiological processes of fish remains to be elucidated. In this study, we ...
  • Defibrotide inhibits donor leucocyte-endothelial interactions and protects against acute graft-versus-host disease 
    García-Bernal, David; Palomo, Marta; Martínez, Carlos-M; Millán-Rivero, José-E; García-Guillén, Ana; Blanquer, Miguel; Diaz-Ricart, Maribel; Sackstein, Robert; Carreras, Enric; Moraleda, José-María (WILEY, 2020-07)
    Allogeneic hematopoietic stem cell transplantation (allo-HCT) is an effective therapy for the treatment of high-risk haematological malignant disorders and other life-threatening haematological and genetic diseases. Acute ...
  • Sex and Time-of-Day Impact on Anxiety and Passive Avoidance Memory Strategies in Mice 
    Meseguer-Henarejos, Ana-Belén; Popovic, Natalija; Bokonjic, Dubravko; Morales-Delgado, Nicanor; Alonso, Antonia; Caballero-Bleda, María; Popovic, Miroljub (FRONTIERS MEDIA SA, 2020)
    In humans, anxiety and cognitive processes are age, gender, and time of day dependent. The purpose of the present study was to assess whether the time of day and sex have an influence on anxiety and emotional memory in ...
  • Validation of Multi-Residue Method for Quantification of Antibiotics and NSAIDs in Avian Scavengers by Using Small Amounts of Plasma in HPLC-MS-TOF 
    Gómez-Ramírez, Pilar; Blanco, Guillermo; García-Fernández, Antonio-Juan (MDPI, 2020-06)
    Pharmaceuticals are still considered emerging pollutants affecting both aquatic and terrestrial ecosystems. Scavenging bird species may be exposed to veterinary drugs when they feed on livestock carcasses provided at ...
  • Effectiveness of Fingolimod versus Natalizumab as Second-Line Therapy for Relapsing-Remitting Multiple Sclerosis in Spain: Second-Line GATE Study 
    Meca-Lallana, José; Ayuso, Teresa; Martínez-Yelamos, Sergio; Duran, Carmen; Contreras-Martín, Yessica; Herrera-Navarro, Nicolas; Pérez-Sempere, Ángel; Álvarez-Cermeno, José-C; Millán-Pascual, Jorge; Meca-Lallana, Virginia; Romero-Sevilla, Raul; Ricart, Javier (KARGER, 2020-05)
    BACKGROUND: There is a lack of head-to-head studies comparing the efficacy of fingolimod (FIN) and natalizumab (NTZ) as second-line therapy for relapsing-remitting multiple sclerosis (RRMS). METHODS: Multicenter, observational ...
  • Time course of bilateral microglial activation in a mouse model of laser-induced glaucoma 
    Ramírez, Ana; de-Hoz, Rosa; Fernández-Albarral, José-A; Salobrar-García, Elena; Rojas, Blanca; Valiente-Soriano, Francisco-Javier; Aviles-Trigueros, Marcelino; Villegas-Pérez, María-Paz; Vidal-Sanz, Manuel; Trivino, Alberto; Ramírez, José-M; Salazar, Juan-J (NATURE PORTFOLIO, 2020-03-17)
    Microglial activation is associated with glaucoma. In the model of unilateral laser-induced ocular hypertension (OHT), the time point at which the inflammatory process peaks remains unknown. Different time points (1, 3, ...
  • Biology and Therapeutic Targets of Colorectal Serrated Adenocarcinoma; Clues for a Histologically Based Treatment against an Aggressive Tumor 
    Alburquerque-González, Begoña; López-Calderón, Fernando-F; López-Abellan, María-Dolores; Esteban-Gil, Ángel; García-Solano, José; Conesa-Zamora, Pablo (MDPI, 2020-03)
    Serrated adenocarcinoma (SAC) is a tumor recognized by the WHO as a histological subtype accounting for around 9% of colorectal carcinomas. Compared to conventional carcinomas, SACs are characterized by a worse prognosis, ...
  • Influence of Preformed Antibodies in Liver Transplantation 
    Legaz, Isabel; Boix, Francisco; López, Manuela; Alfaro, Rafael; Galian, José-A; Llorente, Santiago; Campillo, José-A; Botella, Carmen; Ramírez, Pablo; Sánchez-Bueno, Francisco; Pons, José-A; Moya-Quiles, María-R; Minguela, Alfredo; Muro, Manuel (MDPI, 2020-03)
    The significance of human leukocyte antigen (HLA) matching and preformed donor-specific antibodies (DSAs) in liver transplantation remains unclear. The aim of this study was to analyze the presence of DSAs in a large cohort ...
  • Genome-wide plasma DNA methylation features of metastatic prostate cancer 
    Wu, Anjui; Cremaschi, Paolo; Wetterskog, Daniel; Conteduca, Vincenza; Franceschini, Gian-Marco; Kleftogiannis, Dimitrios; Jayaram, Anuradha; Sandhu, Shahneen; Wong, Stephen-Q; Benelli, Matteo; Salvi, Samanta; Gurioli, Giorgia; Feber, Andrew; Pereira, Maríana-Buongermino; Wingate, Anna-María; González-Billalebeitia, Enrique; De-Giorgi, Ugo; Demichelis, Francesca; Lise, Stefano; Attard, Gerhardt (AMER SOC CLINICAL INVESTIGATION INC, 2020-04-01)
    Tumor DNA circulates in the plasma of cancer patients admixed with DNA from noncancerous cells. The genomic landscape of plasma DNA has been characterized in metastatic castration-resistant prostate cancer (mCRPC) but the ...
  • Spatial and Pregnancy-Related Changes in the Protein, Amino Acid, and Carbohydrate Composition of Bovine Oviduct Fluid 
    Rodríguez-Alonso, Beatriz; Maillo, Verónica; Salvador-Acuna, Omar; López-Ubeda, Rebeca; Torrecillas, Alejandro; Simintiras, Constantine-A; Sturmey, Roger; Aviles, Manuel; Lonergan, Patrick; Rizos, Dimitrios (MDPI, 2020-03)
    Knowledge of how the biochemical composition of the bovine oviduct is altered due to the oviduct anatomy or the presence of an embryo is lacking. Thus, the aim of this study was to assess the effect of (?) oviduct anatomy ...
  • A New Treatment for Mammillary Fistulas Using Ultrasound-Guided Percutaneous Needle Electrolysis 
    Berna-Serna, Juan-de-Dios; García-Vidal, José-Antonio; Escolar-Reina, María-P; Medina-Mirapeix, Francesc; Guzman-Aroca, Florentina; Piñero-Madrona, Antonio; Berna-Mestre, Juan-de-Dios (MDPI, 2020-03)
    The aim of this study was to investigate the efficacy of ultrasound-guided percutaneous needle electrolysis (PNE) in mammillary fistulas (MFs). A prospective study was performed in 18 patients with MF who were treated with ...
  • Expression of tert Prevents ALT in Zebrafish Brain Tumors 
    Idilli, Aurora-Irene; Cusanelli, Emilio; Pagani, Francesca; Berardinelli, Francesco; Bernabé, Manuel; Cayuela, María-Luisa; Poliani, Pietro-Luigi; Mione, María-Caterina (FRONTIERS MEDIA SA, 2020-02-11)
    The activation of a telomere maintenance mechanism (TMM) is an essential step in cancer progression to escape replicative senescence and apoptosis. Alternative lengthening of telomeres (ALT) is found in a subset of malignant ...
  • Child Head Circumference and Placental MFSD2a Expression Are Associated to the Level of MFSD2a in Maternal Blood During Pregnancy 
    Sánchez-Campillo, María; Ruiz-Palacios, María; Ruiz-Alcaraz, Antonio-J; Prieto-Sánchez, María-Teresa; Blanco-Carnero, José-Eliseo; Zornoza-Moreno, Matilde; Ruiz-Pastor, María-José; Demmelmair, Hans; Sánchez-Solis, Manuel; Koletzko, Berthold; Larque, Elvira (FRONTIERS MEDIA SA, 2020)
    Gestational diabetes mellitus (GDM) is a world-wide health challenge, which prevalence is expected to increase in parallel to the epidemic of obesity. Children born from GDM mothers have lower levels of docosahexaenoic ...
  • Living Without Temporal Cues: A Case Study 
    Bonmati-Carrion, María-Ángeles; Revell, Victoria-L; Cook, Tom-J; Welch, Thomas-R-E; Rol, María-Ángeles; Skene, Debra-J; Madrid, Juan-Antonio (FRONTIERS MEDIA SA, 2020-02-07)
    Isolation from external time cues allows endogenous circadian rhythmicity to be demonstrated. In this study, also filmed as a television documentary, we assessed rhythmic changes in a healthy man time isolated in a bunker ...
  • Urban air pollution and hospital admissions for asthma and acute respiratory disease in Murcia city (Spain) 
    Ortega-García, Juan-Antonio; Martínez-Hernández, Indra; Boldo, Elena; Cárceles-Álvarez, Alberto; Solano-Navarro, Carmen; Ramis, Rebeca; Aguilar-Ros, Estefania; Sánchez-Solis, Manuel; López-Hernández, Fernando (EDICIONES DOYMA S A, 2020-08)
    INTRODUCTION: Urban air pollution is a major threat to child and adolescent health. Children are more vulnerable to its effects, being associated with higher morbidity and mortality due to acute and chronic diseases, ...
  • Non-Pharmacological Interventions for Reducing Anxiety in Patients with Potentially Malignant Oral Disorders 
    López-Yufera, Elia; López-Jornet, Pia; Toralla, Oscar; Pons-Fuster-López, Eduardo (MDPI, 2020-03)
    OBJECTIVE: To evaluate the effect of a music intervention upon anxiety, blood pressure, and heart rate in adult patients with potentially malignant oral disorders. METHODS: Eighty consecutive adults (mean age: 68.3 years) ...

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