Repositorio Dspace

Envíos recientes

02. Servicio Murciano de Salud (SMS): Envíos recientes

  • New Potential Pharmacological Options for Endometriosis Associated Pain 
    García-Izquierdo, Laura; Marín-Sánchez, Pilar; García-Penarrubia, Pilar; Martínez-Esparza, María (MDPI, 2024-07)
    Endometriosis is a chronic inflammatory disorder characterized by the abnormal growth of endometrial-like tissue outside the uterine cavity, affecting 10-15% of women of reproductive age. Pain is the most common symptom. ...
  • Molecular Docking Studies of Ortho-Substituted Phenols to Tyrosinase Helps Discern If a Molecule Can Be an Enzyme Substrate 
    Montenegro, María-F; Teruel, José-A; García-Molina, Pablo; Tudela, José; Rodríguez-López, José-Neptuno; García-Cánovas, Francisco; García-Molina, Francisco (MDPI, 2024-07)
    Phenolic compounds with a position ortho to the free phenolic hydroxyl group occupied can be tyrosinase substrates. However, ortho-substituted compounds are usually described as inhibitors. The mechanism of action of ...
  • HELIX Syndrome, a Claudinopathy with Relevant Dermatological Manifestations: Report of Two New Cases 
    Martínez-Romero, María-Carmen; Hernández-Contreras, María-Encarnación; Bafalliu-Vidal, Juan-Antonio; Barreda-Sánchez, María; Martínez-Menchón, Teresa; Cabello-Chaves, Virginia; Guillén-Navarro, Encarna (MDPI, 2024-06)
    HELIX syndrome (Hypohidrosis-Electrolyte disturbances-hypoLacrimia-Ichthyosis-Xerostomia) (MIM#617671) (ORPHA:528105), described in 2017, is due to an abnormal claudin 10 b protein, secondary to pathogenic CLDN10 variants. ...
  • Attitudes, Self-Confidence, and Knowledge of Primary Care Professionals towards School Bullying 
    Celdrán-Navarro, María-del-Carmen; Jiménez-Ruiz, Ismael; Leal-Costa, César; Moore, James-R; López-Barranco, Pedro-Jose (MDPI, 2024-06)
    Attitudes, practices, and knowledge about bullying were evaluated in a sample of 274 primary care professionals, including general practitioners, pediatricians, community, pediatric and school nurses, and residents of these ...
  • The Mediating Role of Exercise in Depression and Fatigue in Patients with Advanced Cancer 
    Calderón, Caterina; Gustems, Marina; Obispo, Berta; García-García, Teresa; Hernández, Raquel; Fernández-Montes, Ana; Jiménez-Fonseca, Paula (MDPI, 2024-06)
    This study explored the interconnections between sociodemographic elements, depression, fatigue, and exercise in patients suffering from incurable neoplasm, particularly emphasizing the mediating influence of exercise on ...
  • Cross-Cultural Validation of the Healthcare Provider's Practices, Attitudes, Self-Confidence, and Knowledge Regarding Bullying Questionnaire 
    del-Carmen-Celdrán-Navarro, María; Jiménez-Ruiz, Ismael; Myriam-Seva-Llor, A; Moore, James-R; Leal-Costa, César (MDPI, 2024-03)
    How can we know the reality of the context of bullying in the field of primary health care? The aim of this study is to obtain a validated and reliable tool that allows measurement of the involvement of primary care ...
  • PRPH2-Related Retinal Dystrophies: Mutational Spectrum in 103 Families from a Spanish Cohort 
    Fernández-Caballero, Lidia; Martín-Merida, Inmaculada; Blanco-Kelly, Fiona; Avila-Fernández, Almudena; Carreno, Ester; Fernández-San-Jose, Patricia; Irigoyen, Cristina; Jiménez-Rolando, Belén; López-Grondona, Fermina; Mahillo, Ignacio; Martín-Gutiérrez, María-Pilar; Minguez, Pablo; Perea-Romero, Irene; Del-Pozo-Valero, Marta; Riveiro-Álvarez, Rosa; Rodilla, Cristina; Rodríguez-Pena, Lidya; Sánchez-Barbero, Ana-Isabel; Swafiri, Saoud-T; Trujillo-Tiebas, María-José; Zurita, Olga; García-Sandoval, Blanca; Corton, Marta; Ayuso, Carmen (MDPI, 2024-03)
    PRPH2, one of the most frequently inherited retinal dystrophy (IRD)-causing genes, implies a high phenotypic variability. This study aims to analyze the PRPH2 mutational spectrum in one of the largest cohorts worldwide, ...
  • Inflammation in Development and Aging: Insights from the Zebrafish Model 
    Mastrogiovanni, Marta; Martínez-Navarro, Francisco-Juan; Bowman, Teresa-V; Cayuela, María-L (MDPI, 2024-02)
    Zebrafish are an emergent animal model to study human diseases due to their significant genetic similarity to humans, swift development, and genetic manipulability. Their utility extends to the exploration of the involvement ...
  • The Microbiota in Long COVID 
    Álvarez-Santacruz, Carmen; Tyrkalska, Sylwia-D; Candel, Sergio (MDPI, 2024-01)
    Interest in the coronavirus disease 2019 (COVID-19) has progressively decreased lately, mainly due to the great effectivity of vaccines. Furthermore, no new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ...
  • Validation of Quantitative Flow Ratio-Derived Virtual Angioplasty with Post-Angioplasty Fractional Flow Reserve-The QIMERA-I Study 
    Amat-Santos, Ignacio-J; Marengo, Giorgio; Sánchez-Luna, Juan-Pablo; Villar, Carlos-Cortes; Crespo, Fernando-Rivero; Diaz, Víctor-Alfonso-Jiménez; Hernández, José-María-de-la-Torre; de-Prado, Armando-Pérez; Sabate, Manel; López-Palop, Ramón; Valle, José-Miguel-Vegas; de-Lezo, Javier-Suárez; Cordon, Clara-Fernández; González, José-Carlos; García-Gómez, Mario; Redondo, Alfredo; Moraleja, Manuel-Carrasco; San-Román, JAlberto (MDPI, 2024-01)
    Background: Quantitative flow ratio (QFR) virtual angioplasty with pre-PCI residual QFR showed better results compared with an angiographic approach to assess post-PCI functional results. However, correlation with pre-PCI ...
  • Validity of the Espiro Mobile Application in the Interpretation of Spirometric Patterns: An App Accuracy Study 
    Savic-Pesic, Darinka; Chamorro, Nuria; López-Rodríguez, Vanesa; Daniel-Diez, Jordi; Torres-Creixenti, Anna; El-Mesnaoui, Mohamed-Issam; Benavides-Navas, Viviana-Katherine; Castellanos-Cotte, José-David; Abellán-Cano, Iván; Da-Costa-Azevedo, Fatima-Alexandra; Trenza-Penas, María; Voelcker-Sala, Inaki; Villalobos, Felipe; Satue-Gracia, Eva-María; Martín-Luján, Francisco; Hung, Iván-Fan-Ngai (MDPI, 2024-01)
    Spirometry is a pulmonary function test where correct interpretation of the results is crucial for accurate diagnosis of disease. There are online tools to assist in the interpretation of spirometry results; however, as ...
  • Challenges of the Implementation of a Delirium Rate Scale in a Pediatric Intensive Care Unit: A Qualitative Approach 
    Balsalobre-Martínez, Paula; Montosa-García, Raquel; Marín-Yago, Ana; Baeza-Mirete, Manuel; Muñoz-Rubio, Gloria-María; Rojo-Rojo, Andrés (MDPI, 2024-01)
    INTRODUCTION: Delirium in the pediatric population admitted to intensive care is a worrying reality due to its potential complications and the increase in associated costs. This study aims to explore the experiences of ...
  • Factor XI in Carriers of Antiphospholipid Antibodies: Elevated Levels Associated with Symptomatic Thrombotic Cases, While Low Levels Linked to Asymptomatic Cases 
    Pagan-Escribano, Javier; Corral, Javier; Miñano, Antonia; Padilla, José; Roldán-Schilling, Vanesa; Hernández-Vidal, María-Julia; Lozano, Jesús; de-la-Morena-barrio, Isabel; Vicente, Vicente; Lozano-Almela, María-Luisa; Herranz, María-Teresa; de-la-Morena-barrio, María-Eugenia (MDPI, 2023-11)
    Antiphospholipid syndrome (APS) is a thromboinflammatory disorder caused by circulating antiphospholipid autoantibodies (aPL) and characterized by an increased risk of thrombotic events. The pathogenic mechanisms of these ...
  • Toxicities and Quality of Life during Cancer Treatment in Advanced Solid Tumors 
    Lee, Eun-Mi; Jiménez-Fonseca, Paula; Galán-Moral, Rocío; Coca-Membribes, Sara; Fernández-Montes, Ana; Sorribes, Elena; García-Torralba, Esmeralda; Punti-Brun, Laura; Gil-Raga, Mireia; Cano-Cano, Juana; Calderón, Caterina (MDPI, 2023-10)
    The purpose of the study was to identify subgroups of advanced cancer patients who experienced grade 3-4 toxicities as reported by their oncologists as well as identify the demographic, clinical, and treatment symptom ...
  • Snijders Blok-Campeau Syndrome: Description of 20 Additional Individuals with Variants in CHD3 and Literature Review 
    Pascual, Patricia; Tenorio-Castaño, Jair; Mignot, Cyril; Afenjar, Alexandra; Arias, Pedro; Gallego-Zazo, Natalia; Parra, Alejandro; Miranda, Lucía; Cazalla, Mario; Silvan, Cristina; Heron, Delphine; Keren, Boris; Popa, Ioana; Palomares, María; Rikeros, Emi; Ramos, Feliciano-J; Almoguera, Berta; Ayuso, Carmen; Swafiri, Saoud-Tahsin; Barbero, Ana-Isabel-Sánchez; Srinivasan, Varunvenkat-M; Gowda, Vykuntaraju-K; Morleo, Manuela; Nigro, Vicenzo; D'Arrigo, Stefano; Ciaccio, Claudia; Mesa, Carmen-Martín; Paumard, Beatriz; Guillén, Gema; Anton, Ana-Teresa-Serrano; Jiménez, Marta-Domínguez; Seidel, Verónica; Suárez, Julia; Cormier-Daire, Valerie; Nevado, Julián; Lapunzina, Pablo (MDPI, 2023-09)
    Snijders Blok-Campeau syndrome (SNIBCPS, OMIM# 618205) is an extremely infrequent disease with only approximately 60 cases reported so far. SNIBCPS belongs to the group of neurodevelopmental disorders (NDDs). Clinical ...
  • Oleanolic Acid Complexation with Cyclodextrins Improves Its Cell Bio-Availability and Biological Activities for Cell Migration 
    Stelling-Ferez, Javier; López-Miranda, Santiago; Gabaldon, José-Antonio; Nicolás, Francisco-Jose (MDPI, 2023-10)
    Wound healing is a complex process to restore skin. Plant-derived bioactive compounds might be a source of substances for the treatment of wounds stalled in a non-resolving stage of wound healing. Oleanolic acid (OA), a ...
  • Genotypic Frequencies of Mutations Associated with Alpha-1 Antitrypsin Deficiency in Unrelated Bone Marrow Donors from the Murcia Region Donor Registry in the Southeast of Spain 
    Cuenca, Irene; Botella, Carmen; Moya-Quiles, María-Rosa; Jiménez-Coll, Víctor; Galian, José-Antonio; Martínez-Banaclocha, Helios; Muro-Pérez, Manuel; Minguela-Puras, Alfredo; Legaz, Isabel; Muro-Pérez, Manuel (MDPI, 2023-09)
    Alpha-1 antitrypsin (AAT1) deficiency (AAT1D) is an inherited disease with an increased risk of chronic obstructive pulmonary disease (COPD), liver disease, and skin and blood vessel problems. AAT1D is caused by mutations ...
  • Clinicians' and Advanced Cancer Patients' Estimates of Treatment Efficacy and Toxicity in Oncologic Treatment 
    Lee, Eun-Mi; Jiménez-Fonseca, Paula; Carmona-Bayonas, Alberto; Hernández, Raquel; Cruz-Castellanos, Patricia; Obispo-Portero, Berta; Antonanzas-Basa, Mónica; Palacin-Lois, María; Castillo-Trujillo, Óscar-Alfredo; Calderón, Caterina (MDPI, 2023-08)
    The purpose of the study was to compare curability expectations between clinicians and patients and examine the influence of sociodemographic and clinical variables on these expectations and satisfaction within the ...
  • Upregulation of Heat-Shock Protein (hsp)-27 in a Patient with Heterozygous SPG11 c.1951C>T and SYNJ1 c.2614G>T Mutations Causing Clinical Spastic Paraplegia 
    García-Carmona, Juan-Antonio; Amores-Iniesta, Joaquín; Soler-Usero, José; Cerdan-Sánchez, María; Navarro-Zaragoza, Javier; López-López, María; Soria-Torrecillas, Juan-José; Ballesteros-Arenas, Ainhoa; Pérez-Vicente, José-Antonio; Almela-Rojo, Pilar (MDPI, 2023-07)
    We report a 49-year-old patient suffering from spastic paraplegia with a novel heterozygous mutation and analyzed the levels of heat shock proteins (hsp)-27, dopamine (DA), and its metabolites in their cerebrospinal fluid ...
  • The Novel Variant NP_00454563.2 (p.Glu259Glyfs*77) in Gene PKP2 Associated with Arrhythmogenic Cardiomyopathy in 8 Families from Malaga, Spain 
    Robles-Mezcua, Ainhoa; Ruiz-Salas, Amalio; Medina-Palomo, Carmen; Robles-Mezcua, María; Diaz-Expósito, Arancha; Ortega-Jiménez, María-Victoria; Gimeno-Blanes, Juan-Ramón; Jiménez-Navarro, Manuel-F; García-Pinilla, José-Manuel (MDPI, 2023-07)
    INTRODUCTION AND OBJECTIVES: Arrhythmogenic cardiomyopathy (ACM) is a hereditary heart disease defined by the progressive replacement of the ventricular myocardium with fibroadipose tissue, which can act as a substrate for ...

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