Repositorio Dspace

Envíos recientes

02. Servicio Murciano de Salud (SMS): Envíos recientes

  • Evaluation of a Primary Health Care Scoliosis Screening Program: A 9-Year Follow-Up Study 
    Ríos-de-Moya-Angeler, Rafael; Santonja-Medina, Fernando; Sanz-Mengibar, José-Manuel; Ríos-Bernabé, Rafael; Hurtado-Avilés, José; Santonja-Renedo, Fernando (MDPI, 2025-05-30)
    Background/Objectives: Scoliosis screening aims to detect spinal deformities early and prevent progression. The Programa de Atención a la Salud de Niños y Adolescentes (PANA) in Spain includes primary care screenings at ...
  • Influence of Familial Inflammatory Bowel Disease History on the Use of Immunosuppressants, Biological Agents and Surgery in Patients with Pediatric-Onset of the Disease in the Era of Biological Therapies. Results from the ENEIDA Registry 
    González-Muñoza, Carlos; Giordano, Antonio; Ricart, Elena; Nos, Pilar; Iglesias, Eva; Gisbert, Javier-P; García-López, Santiago; Mesonero, Francisco; Pascual, Isabel; Tardillo, Carlos; Rivero, Montserrat; Riestra, Sabino; Manosa, Miriam; Zabana, Yamile; Gomollon, Fernando; Calvet, Xavier; García-Sepulcre, Mariana-Fe; Gutiérrez, Ana; Pérez-Calle, José-Lazaro; Sierra-Ausin, Mónica; Bermejo, Fernando; Arias, Lara; Barreiro-de-Acosta, Manuel; Barrio, Jesús; Lorente, Rufo; Guardiola, Jordi; Varela, Pilar; Ponferrada-Díaz, Ángel; Marín-Jiménez, Ignacio; Martínez-Pascual, Cristina; García-Planella, Esther; Domenech, Eugeni (MDPI, 2025-05-12)
    Background: Pediatric-onset familial inflammatory bowel disease (IBD) may differ from sporadic pediatric-onset IBD in its genetic and environmental background and may have distinct clinical and therapeutic implications. ...
  • Association Between Oral Dysbiosis and Alzheimer's Disease: A Systematic Review 
    Martínez-Martínez, Valeria; Rodríguez-Lozano, Francisco-Javier; Pecci-Lloret, María-Pilar; Pérez-Guzmán, Nuria (MDPI, 2025-05-13)
    Objective: The main objective of this systematic review is to select and critically synthesize the available evidence from studies that aimed to verify whether there is a relationship between dysbiosis of the oral cavity ...
  • A Multicenter Study by the DENO Research Group on the Use of Denosumab in Giant-Cell Tumors of the Bone 
    de-la-Calva-Ceinos, Carolina; Angulo, Manuel; González-Rojo, Paula; Peiró, Ana; Machado, Pau; Cebrian, Juan-Luis; García-Maroto, Roberto; Valcárcel, Antonio; Puertas, Pablo; Valero-Cifuentes, Gregorio; Pablos, Oscar; Maireles, Miriam; Fontalva, María-Luisa; Chaves, Iván; Orce, Aida; Coll-Mesa, Luis; Pérez, Israel; González, Fausto; Sanz, María-del-Carmen; Gracia, Isidro (MDPI, 2025-05-07)
    Background/Objectives: Despite the therapeutic potential of denosumab for the treatment of giant-cell tumors of the bone (GCTBs), there is a lack of standardization in treatment protocols. Methods: We present a multicenter, ...
  • Preliminary Results of a Multicenter Randomized Clinical Trial for Laparoscopic Repair of Pelvic Organ Prolapse: Sacropexy vs. Laparoscopic Lateral Suspension 
    Ñíguez-Sevilla, Isabel; Sánchez-Ferrer, María-Luisa; Ruiz-Cotorruelo, Vicente-Luis; Wilczak, Maciej; Chmaj-Wierzchowska, Karolina; Solano-Calvo, Juan-Antonio; Pérez-Munuzuri, María-Elena; Salinas-Pena, Juan-Raúl; Arense-Gonzalo, Julián (MDPI, 2025-03-18)
    Background: Laparoscopic sacropexy (SCL) is the gold standard technique for the correction of apical pelvic organ prolapse (POP). However, other easier laparoscopic techniques, such as laparoscopic lateral suspension (LLS), ...
  • Oral Manifestations of Multiple Sclerosis: A Systematic Review 
    García-Ríos, Paula; Rodríguez-Lozano, Francisco-Javier; Pecci-Lloret, Miguel-Ramón (MDPI, 2025-04-24)
    Background: Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system characterized by diverse clinical manifestations, including the potential involvement of the oral cavity. Oral symptoms in ...
  • Early Prediction of ICU Mortality in Patients with Acute Hypoxemic Respiratory Failure Using Machine Learning: The MEMORIAL Study 
    Villar, Jesús; González-Martín, Jesús-M; Fernández, Cristina; Anon, José-M; Ferrando, Carlos; Mora-Ordonez, Juan-M; Martínez, Domingo; Mosteiro, Fernando; Ambros, Alfonso; Fernández, Lorena; Murcia, Isabel; Vidal, Anxela; Pestana, David; Romera, Miguel-A; Montiel, Raquel; Domínguez-Berrot, Ana-M; Soler, Juan-A; Gómez-Bentolila, Estrella; Steyerberg, Ewout-W; Szakmany, Tamas (MDPI, 2025-03-04)
    Background: Early prediction of ICU death in acute hypoxemic respiratory failure (AHRF) could inform clinicians for targeting therapies to reduce harm and increase survival. We sought to determine clinical modifiable and ...
  • Relationship Between Coronal Plane Alignment of the Knee Phenotypes and Distal Femoral Rotation 
    León-Muñoz, Vicente-J; Hurtado-Avilés, José; Santonja-Medina, Fernando; Lajara-Marco, Francisco; López-López, Mirian; Moya-Angeler, Joaquín (MDPI, 2025-03-01)
    Background: The coronal plane alignment of the knee (CPAK) classification categorises nine phenotypes based on constitutional limb alignment and joint line obliquity and can be used in healthy and arthritic knees. In total ...
  • Clinical and Proteomic Insights into a Cytokine Release Syndrome Triggered by Tebentafusp in a Metastatic Uveal Melanoma Patient: Case Report 
    Lázaro-Sánchez, Antonio-David; Benítez-Fuentes, Javier-David; Luengo-Gil, Ginés; García-García, María-Teresa; Feliciangeli-Moreno, Eduardo; Conesa-Zamora, Pablo; Balsalobre-Yago, José; Mohamed-Mohamed, Kauzar; Arroyo-Rodríguez, Ana-Belén (MDPI, 2025-02-17)
    Background: Uveal melanoma is the most common primary intraocular cancer in adults; however, it remains rare. Despite its rarity, metastatic uveal melanoma poses significant treatment challenges. Tebentafusp, a T-cell ...
  • Observational Study: Preliminary Evaluation of Nostril Narrowing in Relation to Unilateral Mastication 
    Pecci-Lloret, Miguel-Ramón; García-Sampedro, Carmen-María; Guerrero-Gironés, Julia; López-Jiménez, Emilio (MDPI, 2025-02-17)
    Background: Unilateral mastication (UM), defined as the habitual use of one side of the mouth for chewing, has been linked to various craniofacial asymmetries and systemic effects. This study aims to explore the relationship ...
  • Management of Bulky Tumors in Cervical Cancer: Limits of the Surgical Approach 
    Alonso-Espias, María; Pérez-Rocamora, Fátima; Gracia, Myriam; Zapardiel, Ignacio (MDPI, 2025-02-10)
    The standard treatment for cervical tumors larger than 4 cm, known as bulky tumors, currently involves concurrent chemoradiotherapy followed by vaginal brachytherapy. However, radical surgery is an alternative option in ...
  • Semi-Automatic Refinement of Myocardial Segmentations for Better LVNC Detection 
    Barón, Jaime-Rafael; Bernabé, Gregorio; González-Ferez, Pilar; García, José-Manuel; Casas, Guillem; González-Carrillo, Josefa (MDPI, 2025-01-06)
    Background: Accurate segmentation of the left ventricular myocardium in cardiac MRI is essential for developing reliable deep learning models to diagnose left ventricular non-compaction cardiomyopathy (LVNC). This work ...
  • Spinal Cord Stimulation for Refractory Angina Pectoris: Current Status and Future Perspectives, a Narrative Review 
    Gazzeri, Roberto; Mosca, Jacopo; Occhigrossi, Felice; Mercieri, Marco; Galarza, Marcelo; Leóni, Matteo-Luigi-Giuseppe (MDPI, 2025-01-20)
    Refractory angina pectoris (RAP) is a clinical syndrome characterized by persistent chest pain caused by myocardial ischemia that is unresponsive to optimal pharmacological therapy and revascularization procedures. Spinal ...
  • miR-106b-5p as a Central Regulator of Cancer Progression and Chemotherapy-Induced Cardiotoxicity: From Molecular Mechanisms to Clinical Translation 
    Asensio-López, María-del-Carmen; Ruiz-Ballester, Miriam; Bastida-Nicolás, Francisco-José; Soler-Pardo, Fernando; Alonso-Romero, José-Luis; Caro-Martínez, César; Pascual-Figal, Domingo-Andrés; Lax, Antonio (MDPI, 2025-10-14)
    MicroRNAs (miRNAs) are critical regulators of gene expression in cancer biology and cardiovascular disease. miR-106b-5p, a member of the miR-106b-25 cluster, has been widely studied for its oncogenic activity in various ...
  • Systemic Immune and Tumor Marker Profiles in Ovarian and Deep Infiltrating Endometriosis: Associations with Disease Severity and Symptom Burden 
    Ramírez-Pávez, Tamara-Nadira; Marín-Sánchez, María-del-Pilar; Nebot-Navarro, Ana; García-Izquierdo, Laura; Nieto-Meca, Lucía; Sánchez, Rocío; Machado-Linde, Francisco; Martínez-Esparza, María (MDPI, 2025-10-01)
    Endometriosis is a chronic, estrogen-dependent inflammatory disease with heterogeneous clinical manifestations and uncertain systemic immune involvement. This study aimed to characterize peripheral immune profiles and ...
  • Caspase-3 in Brain Death Donors Is Associated with Reduced Primary Graft Dysfunction After Heart Transplantation 
    Herrador, Lorena; González-Costello, José; Niubo-Bosch, Jordi; Calatayud-Samper, Laura; Maestro-Benedicto, Alba; Farrero-Torres, Marta; Blasco-Peiro, Teresa; Almenar-Bonet, Luis; Blázquez-Bermejo, Zorba; Garrido-Bravo, Iris-Paula; Gran-Ipina, Ferran; Grande-Trillo, Antonio; Manito, Nicolas; Moreno-González, Gabriel (MDPI, 2025-09-26)
    Primary graft dysfunction (PGD) remains a major cause of early morbidity and mortality after a heart transplant (HTx). Understanding the donor-related mechanisms involved may help improve organ selection and post-HTx ...
  • Combining CAR T-Cell Therapy and Nivolumab to Overcome Immune Resistance in THRLBCL: A Case Report 
    Munarriz, Daniel; López-Godino, Oriana; Martínez-Cibrian, Nuria; Albiol, Nil; Brillembourg, Helena; Navarro-Velázquez, Sergio; Español-Rego, Marta; Casanueva, Sebastian; García-Tomás, Lucía; Muñoz-Sánchez, Guillermo; Alserawan, Leticia; Benítez-Ribas, Daniel; Magnano, Laura; Correa, Juan-Gonzalo; Rivero, Andrea; Mozas, Pablo; Gine, Eva; Rodríguez-Lobato, Luis-Gerardo; Martínez-Roca, Alexandra; Montoro-Lorite, Mercedes; Ayora, Pilar; Esteve, Jordi; Frutos-Esteban, Laura; Balague-Ponz, Olga; Urbano-Ispizua, Álvaro; González-Navarro, Europa-Azucena; Juan, Manel; Delgado, Julio; Ortiz-Maldonado, Valentin (MDPI, 2025-09-23)
    T-cell/histiocyte-rich large B-cell lymphoma (THRLBCL) is a rare, aggressive subtype of diffuse large B-cell lymphoma characterized by a profoundly immunosuppressive tumor microenvironment. PD-L1 overexpression by tumor ...
  • Docetaxel Resistance in Breast Cancer: Current Insights and Future Directions 
    Postigo-Corrales, Fátima; Beltran-Videla, Asunción; Lázaro-Sánchez, Antonio-David; Hurtado-López, Ana-María; Conesa-Zamora, Pablo; Arroyo-Rodríguez, Ana-Belén; Luengo-Gil, Ginés (MDPI, 2025-07-23)
    Docetaxel is a chemotherapeutic agent widely used for breast cancer treatment; however, its efficacy is often limited by drug resistance and associated toxicity. This review examines the molecular mechanisms of docetaxel ...
  • Expression of Fascin and DNA Topoisomerase 2-Alpha in Breast Carcinoma: Correlation with Histological Subtypes and Other Prognostic Markers 
    Sánchez-Espinosa, Alberto; García-Rodríguez, José; Alonso-Aguirre, Virginia; Acosta-Ortega, Jesús-María; Conesa-Zamora, Pablo; García-Solano, José; Luengo-Gil, Ginés (MDPI, 2025-03-27)
    BACKGROUND/OBJECTIVES: Breast cancer is the most prevalent cancer in adult women. Currently, new therapies and protein determinations with prognostic value are under development. Fascin (encoded by the FSCN1 gene) is an ...
  • An MGRN1-Based Biomarker Combination Accurately Predicts Melanoma Patient Survival 
    Sánchez-Beltrán, José; Soler-Díaz, Javier; Herraiz-Serrano, Cecilia; Olivares, Conchi; Cerdido, Sonia; Cerezuela-Fuentes, Pablo; García-Borrón, Jose-Carlos; Jiménez-Cervantes, Celia (MDPI, 2025-02-18)
    With ever-increasing incidence and high metastatic potential, cutaneous melanoma is the deadliest skin cancer. Risk prediction based on the Tumor-Node-Metastasis (TNM) staging system has medium accuracy with intermediate ...

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