Repositorio Dspace

Envíos recientes

02. Servicio Murciano de Salud (SMS): Envíos recientes

  • VEGF Signaling Pathway Germline Polymorphisms as Prognostic Pharmacogenetic Biomarkers in Localized High-Grade Osteosarcoma Patients from the GEIS-33 Protocol 
    Salazar, Juliana; Arranz, María-J; Martín-Broto, Javier; Serra, Massimo; Palmerini, Emanuela; Martínez-García, Jerónimo; Juan-Ribelles, Antonio; Andion, Maitane; Martínez-Trufero, Javier; Gutiérrez, Guiomar; Echebarria-Barona, Aizpea; Vaz-Salgado, María-A; Regueiro, Alexandra; Álvarez, Rosa; Valverde, Claudia; Luna, Pablo; Blay, Pilar; Sebio, Ana (MDPI, 2025-12-05)
    Background/Objective: The vascular endothelial growth factor (VEGF) signaling pathway induces angiogenesis, which impacts tumor progression and clinical outcomes in patients with localized osteosarcoma. This study evaluates ...
  • Synergizing Virtual Screening and Zebrafish Models to Identify Resveratrol-Derived Antiaging Polyphenols 
    Hernández-Silva, David; Cabello-Villalba, Cynthia; Cayuela-Fuentes, María-Luisa; Pérez-Sánchez, Horacio; Alcaraz-Pérez, Francisca (MDPI, 2025-10-28)
    Background: Telomere shortening and chronic inflammation are well-established hallmarks of aging and age-related diseases, often resulting in impaired cellular function. Identifying compounds with anti-aging potential is ...
  • Host Genetic Factors in Q Fever Susceptibility 
    Robaina-Bordon, José-María; Pérez-Arellano, José-Luis; Montes-Ares, Olga; Torio-Ruiz, Alberto; Hernández-Cabrera, Michele; Pisos-Alamo, Elena; Carranza-Rodríguez, Cristina (MDPI, 2025-04-18)
    Several indirect findings suggest that host-related factors influence susceptibility to Coxiella burnetii infection. We decided to explore the influence of genetic factors related to both innate and adaptive immunity in ...
  • Enhanced Acute Muscle Activation in ALS Patients Following Liposomal Curcumin, Resveratrol, and Dutasteride Administration 
    Martín-Ruiz, Julio; Maset-Roig, Rosa; Caplliure-Llopis, Jordi; Villaron-Casales, Carlos; Alarcón-Jiménez, Jorge; de-Bernardo, Nieves; Proano, Belén; Menargues-Ramírez, Rubén; Selvi-Sabater, Pablo; de-la-Rubia-Orti, José-Enrique (MDPI, 2025-03-28)
    Introduction: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by loss of electrical activity and motor control at the muscular level. Therapeutic alternatives, such as the polyphenolic ...
  • A New Primary Care Model Based on Population Needs: A Nationwide Cross-Sectional Study 
    Domínguez-Fernández, Silvia; García-Martínez, Pedro; Marmol-López, María-Isabel; Nieto-García, Esther; Sánchez-Gómez, María-Begoña; Fontan-Vinagre, M-Guadalupe; Ayuso-Murillo, Diego; Montenegro-Méndez, Susana; Pérez-Rivas, Francisco-Javier (MDPI, 2025-07-08)
    Background/Objectives: The role of the primary health care nurse has evolved since the Spanish Ministry of Health officially established the professional profile of the nurse specialist in Primary Health Care in 2005. ...
  • Mixed Reality in Undergraduate Nursing Education: A Systematic Review and Meta-Analysis of Benefits and Challenges 
    Guillén-Aguinaga, Laura; Rayon-Valpuesta, Esperanza; Guillén-Aguinaga, Sara; Rodríguez-Díaz, Blanca; Montejo, Rocío; Alas-Brun, Rosa; Aguinaga-Ontoso, Enrique; Onambele, Luc; Guillén-Aguinaga, Miriam; Guillén-Grima, Francisco; Aguinaga-Ontoso, Inés (MDPI, 2025-04-22)
    Background: Nursing Schools are incorporating Mixed Reality (MR) into student training to enable them to confront challenging or infrequently encountered scenarios in their practice and ensure their preparedness. This ...
  • Resilience as a Mediator Between Workplace Violence and Psychological Well-Being in Hospital Nurses 
    García-Izquierdo, Mariano; Soler-Sánchez, María-Isabel; de-Haro-García, José-Manuel; Ríos-Rízquez, María-Isabel; Meseguer-de-Pedro, Mariano (MDPI, 2025-06-26)
    Workplace violence is a widespread issue affecting hospital nursing staff and significantly undermines their psychological well-being. Such violence originates from various sources, including users, colleagues, and ...
  • Epidemiological Profile and Risk Factors Related to Sexually Transmitted Infections in Sex Workers in Granada (Spain) 
    Llavero-Molino, Isabel; Sánchez-Torres, María; Hueso-Montoro, César; González-García, Alberto; García-García, Inmaculada; Jiménez-Bautista, Francisco; Pérez-Morente, María-Ángeles (MDPI, 2025-02-28)
    Background: Sex work is one of the oldest trades in the world. It is the practice of sexual activity in exchange for money or material goods. It has traditionally been carried out by women, although in recent years, there ...
  • Polyphenol-Related Gut Metabotype Signatures Linked to Quality of Life in Postmenopausal Women: A Randomized, Placebo-Controlled Crossover Trial 
    Jarrin-Orozco, María-P; Romo-Vaquero, María; Carrascosa, Concepción; Pertegal-Ruiz, Miriam; Berna, José; Puigcerver, Julio; Saura-Sanmartin, Adrián; Espinosa-Salinas, Isabel; García-Nicolás, María; Ávila-Galvez, María-A; Espín, Juan-C (MDPI, 2025-11-15)
    Background/Objectives: Interindividual variability in polyphenol metabolism may help explain the inconsistent effects of polyphenol intake on health outcomes. This study compared, for the first time, (i) polyphenol-related ...
  • Association of Dietary Advanced Glycation End Products with Overall and Site-Specific Cancer Risk and Mortality: A Systematic Review and Meta-Analysis 
    Pascual-Morena, Carlos; Garrido-Miguel, Miriam; Martínez-García, Irene; Luceron-Lucas-Torres, Maribel; Rodríguez-Gutiérrez, Eva; Berlanga-Macias, Carlos; Fernández-Bravo-Rodrigo, Jaime; Patino-Cardona, Silvana (MDPI, 2025-05-10)
    Background/Objectives: Dietary advanced glycation end products (dAGEs) have a pro-inflammatory effect and increase oxidative stress, potentially leading to cancer. The aim of this study was to estimate the association ...
  • Understanding the Natural History and the Effects of Current Therapeutic Strategies on Urea Cycle Disorders: Insights from the UCD Spanish Registry 
    Martín-Hernández, Elena; Bellusci, Marcello; Pérez-Mohand, Patricia; Correcher-Medina, Patricia; Blasco-Alonso, Javier; Morais-López, Ana; de-las-Heras, Javier; Meavilla-Olivas, Silvia-María; Dougherty-de-Miguel, Lucy; Couce, María-Luz; Canedo-Villarroya, Elvira; García-Jiménez, María-Concepción; Moreno-Lozano, Pedro-Juan; Vives-Piñera, Inmaculada; Gil-Campos, Mercedes; Stanescu, Sinziana; Ceberio-Hualde, Leticia; Camprodon, María; Cortés-Saladelafont, Elisenda; López-Urdiales, Rafael; Murray-Hurtado, Mercedes; Márquez-Armenteros, Ana-María; Sierra-Córcoles, Concha; Peña-Quintana, Luis; Ruiz-Pons, Mónica; Alcalde, Carlos; Castellanos-Pinedo, Fernando; Dios, Elena; Barrio-Carreras, Delia; Martín-Cazana, María; García-Peris, Mónica; Andrade, José-David; García-Volpe, Camila; de-los-Santos, Mariela; García-Cazorla, Angels; del-Toro, Mireia; Felipe-Rucian, Ana; Comino-Monroy, María-José; Sánchez-Pintos, Paula; Matas, Ana; Gil-Ortega, David; Martín-Rivada, Álvaro; Bergua, Ana; Belanger-Quintana, Amaya; Vitoria, Isidro; Yahyaoui, Raquel; Pérez, Belén; Morales-Conejo, Montserrat; Quijada-Fraile, Pilar (MDPI, 2025-03-28)
    Background/Objectives: The present study updates the Spanish registry of patients with urea cycle disorders (UCD), originally established in 2013, to provide comprehensive epidemiological data and evaluate the impact of ...
  • Diet, Advanced Maternal Age, and Neonatal Outcomes: Results from the GESTAGE Study 
    Puche-Juarez, María; Toledano, Juan-M; Hinojosa-Nogueira, Daniel; de-Paco-Matallana, Catalina; Sánchez-Romero, Javier; Ochoa, Julio-J; Carrillo, María-Paz; Martín-Álvarez, Estefanía; Díaz-Castro, Javier; Moreno-Fernández, Jorge (MDPI, 2025-01-17)
    Maternal nutrition during pregnancy plays a pivotal role in influencing both maternal and fetal health, impacting neonatal anthropometric outcomes and long-term disease susceptibility. An advanced maternal age (AMA ? 35 ...
  • Graphene-Based Materials for Bone Regeneration in Dentistry: A Systematic Review of In Vitro Applications and Material Comparisons 
    Narváez-Romero, Azahara-María; Rodríguez-Lozano, Francisco-Javier; Pecci-Lloret, María-Pilar (MDPI, 2025-01-08)
    INTRODUCTION: Graphene, a two-dimensional arrangement of carbon atoms, has drawn significant interest in medical research due to its unique properties. In the context of bone regeneration, graphene has shown several promising ...
  • Incidence and Survival of IDH-Wildtype Glioblastoma and IDH-Mutant Astrocytoma by Treatment and Sex: A Regional Study in Spain (2011-2021) 
    Encarnación-Navarro, Juan-Antonio; Mansó-Murcia, Clara; Royo-Villanova, Mario; Ruiz, P; de-la-Fuente-Muñoz, Isabel; Cárdenas-Cánovas, Enrique; Ros-Martínez, Silverio; Alonso-Romero, José-Luis (MDPI, 2025-10-14)
    BACKGROUND: The incidence and prognosis of high-grade gliomas differ according to histopathological and molecular features. The WHO 2021 CNS classification emphasized IDH status, but historical cohorts often lacked systematic ...
  • Prediction of Small for Gestational Age and Growth-Restricted Neonates at 35 to 36 Weeks of Gestation: A Multicenter Cohort Study 
    Martín-Alonso, Raquel; de-Paco-Matallana, Catalina; Valino, Nuria; Chaveeva, Petya; Dagklis, Themistoklis; Siargkas, Antonios; Wright, Alan; Camacho, Mario; Rolle, Valeria; Santacruz, Belén; Gil, María-M (MDPI, 2025-09-08)
    Background and Objectives: Third-trimester screening is widely used to identify small for gestational age (SGA) and fetal growth restriction (FGR), but optimal models and timing remain under investigation. This study aimed ...
  • Outcomes of Kidney Transplantation from Deceased Donors with Severe Acute Kidney Injury (AKIN Stage 3): A Preliminary Single-Centre Analysis 
    Encarnación-Navarro, Juan-Antonio; Coll, Elisabeth; Mansó-Murcia, Clara; Llorente-Vinas, Santiago; Morales, Francisco; Saura, Isabel; López-Cubillana, Pedro; Guzmán-Martínez-Valls, Pablo-Luis; Martínez, Gloria; de-la-Fuente-Muñoz, Isabel; Cárdenas-Cánovas, Enrique; Alonso-Romero, José-Luis; Ruiz-Carreño, Paula; Moya-Sánchez, José; Domínguez-Gil, Beatriz; Royo-Villanova, Mario (MDPI, 2025-09-14)
    BACKGROUND: The shortage of donor kidneys has prompted interest in using organs from donors with severe acute kidney injury (AKI), but robust data on outcomes from donors with AKIN stage 3 remain limited. METHODS: This ...
  • Use of Social Media by Health Science Degree Students in the Field of Organ Donation and Transplantation 
    Almela-Baeza, Javier; Ferrigno, Cristiana; Febrero, Beatriz (MDPI, 2025-07-19)
  • Clinical and Prognostic Differences Between Mechanical Versus Biological Prosthetic Infective Endocarditis-A Nationwide Database Study 
    de-Villarreal-Soto, Juan-Esteban; Calderón-Parra, Jordi; Muñoz-García, Patricia; Cuerpo-Caballero, Gregorio; Machado-Vílchez, Marina; Rodríguez-Esteban, María-Ángeles; Rodríguez-García, Raquel; Tascon-Quevedo, Valentin; Goikoetxea-Agirre, Ane-Josune; Quintana-Obrador, Eduard; Goenaga-Sánchez, Miguel-Ángel; García-Vázquez, Elisa; Hernández-Estefania, Rafael; Ramos-Martínez, Antonio; Martín-López, Carlos-Esteban (MDPI, 2025-12-13)
    Objectives: Infective endocarditis (IE) is a feared and life-threatening complication, requiring a multidisciplinary approach. Prosthetic valve endocarditis (PVE) accounts for 20-30% of IE, is one of the most severe forms ...
  • Exercise-Based Prehabilitation Before Cardiac Surgery: A Systematic Review, Meta-Analysis, Meta-Regression, and Proposal for a Clinical Implementation Model 
    Hurtado-Borrego, Juan-Carlos; Bayonas-Ruiz, Adrián; Bonacasa, Barbara (MDPI, 2025-11-19)
    Background/Objectives: Major cardiac surgery is associated with a high rate of postoperative complications, particularly in older and frail patients. Prehabilitation-defined as a preoperative intervention based on structured ...
  • The Impact of Ursodeoxycholic Acid on Fetal Cardiac Function in Women with Gestational Diabetes Mellitus: A Randomized Controlled Study (GUARDS Trial) 
    Company-Calabuig, Ana-María; Blanco-Carnero, José-Eliseo; Chatzakis, Christos; Williamson, Catherine; Nicolaides, Kypros-H; Charakida, Marietta; de-Paco-Matallana, Catalina (MDPI, 2025-10-17)
    Background: Gestational diabetes mellitus (GDM) is associated with subclinical alterations in fetal cardiac morphology and function. Ursodeoxycholic acid (UDCA), widely used in pregnancy for intrahepatic cholestasis, has ...

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