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Repositorio Institucional en Ciencias de la Salud de la Región Murcia: Envíos recientes

  • Efficacy and safety of the PHIL embolic agent in the treatment of intracranial dural arteriovenous fistulas: results of the PHIL-dAVF study 
    Marnat, Gaultier; Barreau, Xavier; Januel, Anne-Christine; Spelle, Laurent; Piotin, Michel; Mounayer, Charbel; Borota, Ljubisa; González, Alejandro; Casasco, Alfredo; Keston, Peter; Lobotesis, Kyriakos; Cronqvist, Mats; Holtmannspotter, Markus; Guimaraens, Leopoldo; Boccardi, Edoardo; Valvassori, Luca; Espinosa-de-Rueda, Mariano; Cognard, Christophe; PHIL-DAVF-Study-Investigators (BMJ PUBLISHING GROUP, 2026-01)
    BACKGROUND AND PURPOSE: Embolization is the first-line treatment for dural arteriovenous fistulas (dAVF). The precipitating hydrophobic injectable liquid (PHIL) embolic agent is a non-adhesive copolymer with specific ...
  • Does lifestyle explain the relationship between socioeconomic position and multimorbidity of cancer and cardiometabolic diseases? A mediation analysis applied to the European Prospective Investigation into Cancer and Nutrition 
    Manfredi, Luca; Buscema, Federica; Giraudo, María-Teresa; Sodano, Barbara; Padroni, Lisa; Destefanis, Cinzia; Freisling, Heinz; Ferrari, Pietro; Cesaroni, Giulia; Uzzau, Sergio; Schulze, Matthias-B; Saieva, Calogero; Tumino, Rosario; Weiderpass, Elisabete; Matta, Komodo; Vaccarella, Salvatore; Guevara, Marcela; Halkjaer, Jytte; Tjonneland, Anne; Crous-Bou, Marta; Katzke, Verena; Pour, Toktam; Panico, Salvatore; Pala, Valeria; Tzoulaki, Ioanna; Tin-Tin, Sandar; Dahm, Christina-C; Chirlaque-López, María-Dolores; Sacerdote, Carlotta; Ricceri, Fulvio (BMJ PUBLISHING GROUP, 2026-01)
    BACKGROUND: Multimorbidity is socially patterned, with lower socioeconomic position (SEP) linked to higher risk. We examined whether a Healthy Lifestyle Index (HLI) mediates the SEP-multimorbidity association and whether ...
  • Examining causal relationships between educational attainment and type 2 diabetes using genetic analysis: findings from the EPIC-InterAct study through Mendelian randomisation 
    Macciotta, Alessandra; Sacerdote, Carlotta; Giachino, Claudia; Di-Girolamo, Chiara; Franco, Matteo; van-der-Schouw, Yvonne-T; Zamora-Ros, Raúl; Weiderpass, Elisabete; Domenighetti, Cloe; Elbaz, Alexis; Truong, Therese; Agnoli, Claudia; Bendinelli, Benedetta; Panico, Salvatore; Vineis, Paolo; Christakoudi, Sofia; Schulze, Matthias-B; Katzke, Verena; Bajracharya, Rashmita; Dahm, Christina-C; Dalton, Susanne-Oksbjerg; Colorado-Yohar, Sandra; Moreno-Iribas, Conchi; Amiano-Etxezarreta, Pilar; Sánchez, María-José; Forouhi, Nita-G; Wareham, Nicholas; Ricceri, Fulvio (BMJ PUBLISHING GROUP, 2025-05)
    INTRODUCTION: Observational studies have shown that more educated people are at lower risk of developing type 2 diabetes (T2D). However, robust study designs are needed to investigate the likelihood that such a relationship ...
  • Intrahepatic donor microbiota-based metataxonomic signature detected in organ preservation solution enables prediction of short-term liver transplant outcomes 
    Lucas-Ruiz, Fernando; Vidal-Correoso, Daniel; V; de-la-Torre-Álamo, María-Magdalena; Jover-Aguilar, Marta; Alconchel-Gago, Felipe; Martínez-Alarcón, Laura; López-López, Víctor; Ríos-Zambudio, Antonio; Cascales-Campos, Pedro-Antonio; Pelegrín, Pablo; Pons-Miñano, José-Antonio; Ramírez, Pablo; Baroja-Mazo, Alberto (BMJ PUBLISHING GROUP, 2025-12)
    BACKGROUND: Liver transplantation (LT) remains hampered by post-transplant complications. While gut microbiota dysbiosis has been linked to transplant outcomes, the role of the intrahepatic graft's native microbiota remains ...
  • Withdrawal of antitumour necrosis factor in inflammatory bowel disease patients in remission: a randomised placebo-controlled clinical trial of GETECCU 
    Gisbert, Javier-P; Donday, María-G; Riestra, Sabino; Lucendo, Alfredo-J; Benítez, José-Manuel; Navarro-Llavat, Merce; Barrio, Jesús; Morales-Alvarado, Víctor-J; Rivero, Montserrat; Busquets, David; Leo-Carnerero, Eduardo; Merino, Olga; Nantes-Castillejo, Oscar; Navarro, Pablo; Van-Domselaar, Manuel; Gutiérrez, Ana; Alonso-Abreu, Inmaculada; Mejuto, Rafael; Fernández-Salazar, Luis; Iborra, Marisa; Martín-Arranz, María-Dolores; Pineda, Juan-Ramón; Sampedro, Manuela-Josefa; Serra-Nilsson, Katja; Bouhmidi, Abdel; Batista, Lissette; Muñoz-Villafranca, Carmen; Rodríguez-Lago, Iago; Ceballos, Daniel; Guerra, Iván; Manosa, Miriam; Marín-Jiménez, Ignacio; Torrella-Cortés, Emilio; Vera-Mendoza, Maribel; Casanova, María-José; de-Francisco, Ruth; Arias-González, Laura; Marín-Pedrosa, Sandra; García-Bosch, Orlando; García-Alonso, Francisco-Javier; Delgado-Guillena, Pedro; García, María-José; Torrealba, Leyanira; Núñez-Ortiz, Andrea; Vicuna-Arregui, Miren; Bosca-Watts, Marta-Maia; Blázquez, Isabel; Acosta, Diana; Garre, Ana; Baldan, Montse; Martínez, Concepción; Barreiro-de-Acosta, Manuel; Domenech, Eugeni; Esteve, María; García-Sánchez, Valle; Nos, Pilar; Panes, Julián; Chaparro, María (BMJ PUBLISHING GROUP, 2025-03)
    BACKGROUND AND OBJECTIVES: Primary objectives: to compare the rates of sustained clinical remission at 12 months in patients treated with antitumour necrosis factor (anti-TNF) and immunomodulators who withdraw anti-TNF ...
  • Death risk in nursing homes between the prepandemic period and the COVID-19 era: a retrospective cohort study in Murcia Region, Spain 
    Gómez-Gómez, Jesús-Humberto; Sánchez-Rodríguez, Inés; Soriano-López, Jesús; García-Pina, Rocío; Cabrera-Castro, Natalia-Alejandra; Moreno-Diaz, Marían-Inmaculada; Conesa-Hernández, Ana-María; Sola-Roca, Antonio; Molina-de-los-Cobos, Enrique; Sánchez-Montesinos, María-Carmen; Palomar-Rodríguez, Joaquín; Chirlaque-López, María-Dolores (BMJ PUBLISHING GROUP, 2025-07)
    BACKGROUND: With the end of COVID-19 status as a public health emergency of international concern, evaluating its effects on vulnerable groups like nursing home residents is crucial. We aimed to examine the mortality risk ...
  • Practice of oxygenation and respiratory support during fibreoptic bronchoscopy: the OxyFOB study protocol 
    Longhini, Federico; Crimi, Claudia; Noto, Alberto; Pelaia, Corrado; Karakurt, Zuhal; Skoczynski, Szymon; Boleo-Tome, José-Pedro; Winck, Joao-Carlos; Esquinas-Rodríguez, Antonio; Melhorn, James; Corneci, Dan; Pobeha, Pavol; Bosco, Vincenzo; Garofalo, Eugenio; Bruni, Andrea; Cammarota, Gianmaria; Todorova, Violeta; Puci, Mariangela-Valentina; Sotgiu, Giovanni; Kostikas, Konstantinos; Maggiore, Salvatore-Maurizio; De-Robertis, Edoardo; Ergan, Begum; Landoni, Giovanni; Simonte, Rachele; Nava, Stefano; Navalesi, Paolo; Scala, Raffaele (BMJ PUBLISHING GROUP, 2025-09)
    INTRODUCTION: Flexible bronchoscopy (FB) is widely used for diagnostic and therapeutic procedures in pulmonary medicine. However, FB can cause respiratory and haemodynamic complications, especially in patients with ...
  • Novel tube and inhaler adaptor for non-invasive ventilation: from design to clinical impact 
    Quintero, Óscar-Iván; García-García, María-Paula; Valdés, Carlos-Andrés; Pinzón-Hernández, Nicolás; I; Esquinas-Rodríguez, Antonio (BMJ PUBLISHING GROUP, 2025-04)
  • Differential pathological dynamics triggered by distinct Parkinson patient-derived ?-synuclein extracts in nonhuman primates 
    Kinet, R; Bourdenx, M; Dovero, S; Darricau, M; Arotcarena, M-l; Camus, S; Porras, G; Thiolat, M-l; Trigo-Damas, I; Bohic, S; Morari, M; Doudnikoff, E; Goikoetxea, M; Claverol, S; Tokarski, C; Kruse, N; Mollenhauer, B; Estrada, C; García-Carrillo, Nuria; Herrero, María-Trinidad; Vila, M; Obeso, J-A; Bezard, E; Dehay, B (AMER ASSOC ADVANCEMENT SCIENCE, 2025-06-20)
    The presence of ?-synuclein (?-syn) aggregates, such as Lewy bodies in patients with Parkinson's disease (PD), contributes to dopaminergic cell death. Injection of PD patient-derived ?-syn in nonhuman primates has illustrated ...
  • Efficacy of Combined vs. Monotherapy in Oral Lichen Planus: A Randomized Clinical Trial 
    Rodríguez-Galvez, Rocío; Tvarijonaviciute, Asta; Peres-Rubio, Camila; López-Jornet, Pía (WILEY, 2025-02)
    OBJECTIVES: The aim of this study was to compare the topical therapeutic efficacy of triamcinolone acetonide (TA) (0.2%) plus hyaluronic acid (HA) (0.1%) versus monotherapy in patients with symptomatic oral lichen planus ...
  • New Stent Retriever Technology Versus Standard Devices for Anterior Large Vessel Thrombectomy: A Multicenter Study 
    Puig, Josep; Dolz, Guillem; Werner, Mariano; Daunis-i-Estadella, Pepus; Comas-Cufi, Marc; Tomasello, Alejandro; González, Eva; Manso-del-Cano, Xabier; Vega, Pedro; Murias, Eduardo; Bravo, Isabel; Jiménez, Elvira; Aparici-Robles, Fernando; Sanchis, Juan-Manuel; Remollo, Sebastia; Castaño, Carlos; Moreu, Manuel; López-Frias, Alfonso; Terceno, Mikel; Silva, Yolanda; Chirife, Oscar; López-Rueda, Antonio; Martínez-Fernández, Javier; Méndez, José-Carlos; Sagredo, Antonio; Diaz-Pérez, Jose; Cuba, Victor; Llibre, José-Carlos; Aguilar, Yeray; SanRoman, Luis; Blasco, Jordi (WILEY, 2025-11)
    BACKGROUND AND PURPOSE: Guidelines recommend stent retrievers (SRs) for treating large vessel occlusion (LVO) stroke. We assessed noninferiority of the iNtercept (iVascular) SR with a self-expanding basket on a pusher wire ...
  • Contact Aspiration Alone or Combined With Stent Retriever Thrombectomy for Middle Cerebral Artery Large Vessel Occlusion 
    Navia, Pedro; Fernández-Prieto, Andrés; Álvarez-Muelas, Alberto; Calleja, Ángel; Ortega, Joaquín; Domínguez, Carlos; Sagredo, Antonio; Rodríguez-Benítez, Amado; García-Villanego, Juan; Martínez-Calvo, Alberto; Cubillo-Prieto, Daniel; de-la-Rosa, Carmen; Mosqueira, Antonio; Bermejo-Garces, Rebeca; Chaviano, Juan; Bermúdez-Coronel, Isabel; Pérez-García, Carlos; Rodríguez-Paz, Carlos-Manuel; Hidalgo-Barranco, Carlos; Maynar, Javier; Caniego, José-Luis; Molina-Nuevo, Juan-David; Maestro, Victor; Sanchis-García, Juan-Manuel; Balboa, Oscar; Martínez-Galdamez, Mario; Garmendia, Enaut; Comas-Cufi, Marc; Puig, Josep; Zamarro-Parra, Joaquín (WILEY, 2025-07)
    BACKGROUND AND PURPOSE: The effectiveness of a large-bore aspiration catheter for contact aspiration (CA) thrombectomy is compared to the combined use of an aspiration catheter and a stent retriever (CA+SR) for large vessel ...
  • Distal Access Catheter Improves Balloon Guide and Stent Retriever Thrombectomy Outcomes in Nonagenarians 
    Puig, Josep; Werner, Mariano; Dolz, Guillem; Pascagaza, Alejandro; Daunis-i-Estadella, Pepus; Comas-Cufi, Marc; González, Eva; Fondevila, Jon; Vega, Pedro; Murias, Eduardo; Romero, Veredas; Martínez, Carlos; Aparici-Robles, Fernando; Morales-Caba, Lluis; Remollo, Sebastia; Rodríguez-Caamano, Isabel; Pérez-García, Carlos; Rosati, Santiago; Bashir, Saima; Vielba-Gómez, Isabel; Aixut, Sonia; Paipa, Andrés-Julián; Martínez-Fernández, Javier; Aguilar, Yeray; Fandino, Eduardo; Barbieri, Giorgio; García-Villalba-Navaridas, Blanca; Cuba, Victor; Castaño, Miguel; Blasco, Jordi; ROSSETTI-Grp (WILEY, 2025-01)
    BACKGROUND AND PURPOSE: The safety and effectiveness of endovascular techniques in elderly patients with large vessel occlusion (LVO) remain controversial. We investigated the angiographic and clinical outcomes of nonagenarians ...
  • New cases of ?-aminolevulinic acid dehydratase deficiency: Functional insights into gene variants using an innovative mouse liver model 
    Di-Pierro, Elena; Solares, Isabel; Jerico, Daniel; Castelbon, Francisco-J; Tomás-Solera, Javier; Riera-mestre, Antoni; Barreda-Sánchez, María; Poci, Carlo; Nicolli, Annamaria; Urigo, Francesco; Sampedro, Ana; Enríquez-de-Salamanca, Rafael; Marcacci, Matteo; Ávila, Matias-A; Harper, Pauline; Fanlo-maresma, Marta-G; Guillén-Navarro, Encarna; Graziadei, Giovanna; Wenzel, Andrea; Beck, Bodo-B; Ventura, Paolo; Morales-conejo, Montserrat; Fontanellas, Antonio (WILEY, 2026-01)
    BACKGROUND: Dysfunction of ?-aminolevulinic acid dehydratase (ALAD), the second enzyme involved in heme biosynthesis, leads to two pathologies: genetic and acquired. The genetic form is an ultrarare, severe childhood-onset ...
  • Cultivating Compassion in Students for End-Of-Life Processes: A Mixed-Methods Participatory Research Protocol 
    Abad-Corpa, Eva; Espinosa-Sánchez, Miriam; Barnestein-Fonseca, Pilar; Camacho-Bejarano, Rafaela; Delgado-Hito, Pilar; Miró-Bonet, Rosa (WILEY, 2025-10-11)
    AIMS: To analyse the impact of a participatory process of awareness and reflection on compassion, in the face of end-of-life processes, in students aged 12-23 years in six Spanish regions, and to understand how the ...
  • Establishing Epidemic and Intensity Thresholds After a Major Change in Respiratory Virus Surveillance in Spain in 2020 
    Puerto, Ana-María; Lozano, José-Eugenio; Lozano, Marcos; Basile, Luca; Naveira-Barbeito, Gael; Guiu-Canete, Inés; Linares-Dopido, Juan-Antonio; Fernández-Ibáñez, Ana; Ibáñez-Pérez, Ana-Carmen; Castrillejo, Daniel; Rivas-Wagner, Eva; Valcárcel-de-la-Iglesia, María-Ángel; Pérez-Morilla, Esteban; Martínez-Pino, Isabel; Vega, Tomas; Monge, Susana (WILEY, 2025-09)
    OBJECTIVES: We estimated acute respiratory infections (ARIs) and influenza-like illness (ILI) thresholds for SiVIRA, a new integrated surveillance system set up in Spain in 2020. METHODS: We retrospectively extracted ...
  • COVID-19 Vaccine Effectiveness Against Medically Attended Symptomatic SARS-CoV-2 Infection Among Target Groups in Europe, October 2024-January 2025, VEBIS Primary Care Network 
    Delaunay, Charlotte-Laniece; Verdasca, Nuno; Monge, Susana; Domegan, Lisa; Seve, Noemie; Buda, Silke; Meijer, Adam; Lucaccioni, Heloise; López-Torrijos, Miriam; Mckenna, Adele; Enouf, Vincent; Duerrwald, Ralf; In't-Velt, Eline; de-Valcárcel-Laiglesia, Ma-Angel; Bennett, Charlene; Masse, Shirley; Erdwiens, Annika; Hooiveld, Mariette; Mlinaric, Ivan; Turi, Gergo; Rodrigues, Ana-Paula; Martínez-Baz, Iván; Lazar, Mihaela; Latorre-Margalef, Neus; Borges, Vitor; Kaczmarek, Marlena; Bacci, Sabrina; Kissling, Esther; European-Primary-Care-VE-Group (WILEY, 2025-05)
    We estimated the effectiveness of 2024/25 COVID-19 vaccination against medically attended SARS-CoV-2 infection in Europe, among target groups. We included 3204 patients (8/139 cases vaccinated: 6%; 517/3065 controls ...
  • Real-world effectiveness and safety of galcanezumab for the treatment of migraine: A systematic review and meta-analysis 
    Fernández-Bravo-Rodrigo, Jaime; Pascual-Morena, Carlos; Saz-Lara, Alicia; Martínez-García, Irene; Lever-Megina, Carla-Geovanna; Patino-Cardona, Silvana; Flor-García, Amparo; Cavero-Redondo, Iván (WILEY, 2026-01)
    OBJECTIVE: This study aimed to summarize and pool real-world evidence on the clinical effectiveness and safety of galcanezumab. BACKGROUND: Migraine is a disabling primary headache disorder. Several drugs that target ...
  • Teleost-specific ictacalcins exhibit similar structural organization, cation-dependent activation, and transcriptional regulation as human S100 proteins 
    Hernández, Liz; Paris, Theo; Demou, María; Birck, Catherine; Begon-pescia, Christina; Rodríguez-Vidal, Juan-Francisco; Tyrkalska, Sylwia-D; Bureau, Charlotte; González, Catherine; Gracia, Juliette; Lelievre, Etienne; Mulero, Víctoriano; Nguyen-chi, Mai; Yatime, Laure (WILEY, 2025-11-28)
    S100 proteins are highly versatile calcium-binding proteins from vertebrates. Following extracellular release, they become essential in immune and antimicrobial defenses, initiating the inflammatory response through receptor ...
  • Shared Decision-Making in Treatment Selection in Multiple Myeloma in Spain: The PRISMMA Study 
    Cabanas-Perianes, Valentín; Casanova, María; Barragán, Begoña; López, Isabel; Raya, Anna; Santiago-Josefat, Belén (WILEY, 2026-02)
    INTRODUCTION: Perceptions and experiences of shared decision-making between patients and physicians in multiple myeloma (MM) care are not fully understood. A survey study was conducted to explore these perspectives in ...