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Envíos recientes

Repositorio Institucional en Ciencias de la Salud de la Región Murcia: Envíos recientes

  • Lipidomics Unveils Critical Lipid Pathway Shifts in Alport Syndrome 
    Requena, Belen; Shabaka, Amir; Lanzon, Borja; Martinez, Sara; Carrillo, Isabel Galan; Bada-Bosch, Teresa; Sevillano, Angel; Tato-Ribera, Ana Maria; Barbas, Coral; Medina-Gomez, Gema; Gonzalez-Riano, Carolina; Fernandez-Juarez, Gema (ELSEVIER SCIENCE INC, 2025-08)
    INTRODUCTION: Alport syndrome (AS) is a hereditary kidney disease from COL4A3-5 pathogenic variants causing glomerular basement membrane abnormalities. Although genetic and structural aspects are known, mechanisms linking ...
  • Identifying Predictors for Heart Failure Outcomes in Phospholamban p.(Arg14del)-Positive Individuals 
    van-der-Heide, Myrthe-Y-C; Verstraelen, Tom-E; de-Brouwer, Remco; van-Drie, Esmee; Proost, Virginnio-M; van-Lint, Freyja-H-M; Bosman, Laurens-P; Houweling, Arjan-C; Dickhoff, Cathelijne; Germans, Tjeerd; Schoonderwoerd, Bas-A; Gimeno-Blanes, Juan-Ramón; Meems, Laura-M-G; te-Riele, Anneline-S-J-M; van-Spaendonck-Zwarts, Karin-Y; Cox, Moniek-G-P-J; Amin, Ahmad-S; van-Tintelen, J-Peter; de-Boer, Rudolf-A; Zwinderman, Aeilko-H; Wilde, Arthur-A-M (ELSEVIER SCI LTD, 2025-10)
    BACKGROUND: Phospholamban (PLN) p.(Arg14del)-positive individuals are at high risk of developing PLN p.(Arg14del)-related cardiomyopathy, which can lead to progressive heart failure that is poorly amenable to standard heart ...
  • Concentration-dependent biphasic toxicity and steroidogenic stimulation by aminocarb in murine Leydig cells 
    Moreira, Silvia; Martins, Ana-D; Bernardino, Raquel-L; Pinho, Marisa; Guerra, Inés-M-S; Alves, Marco-G; Pastor, Luis-Miguel; Seco-Rovira, Vicente; Pereira, María-de-Lourdes; Oliveira, Pedro-F; Domingues, M-Rosario (ELSEVIER, 2025-09)
    Exposure to environmental chemicals, like pesticides, can impair male reproductive health by affecting Leydig cell (LC) function. This study investigated aminocarb, a widely used carbamate pesticide, and its impact on ...
  • Efficacy and safety of efavirenz in Niemann-Pick disease type C 
    Gascon-Bayarri, Jordi; Rico, Inmaculada; Sanchez-Castaneda, Cristina; Ledesma, Maria Dolores; Carnaval, Thiago; Bejr-Kasem, Helena; Campdelacreu, Jaume; Ferrer, Anna; Rodriguez-Bel, Laura; Cos, Monica; de Lama, Eugenia; de Munain, Adolfo Lopez; Rouco, Idoia; Perez-Sousa, Celia; Cerdan, Maria; Muelas, Nuria; Sevillano, Maria Dolores; Mir, Pablo; Villoria, Jesus; Videla, Sebastian (ELSEVIER SCIENCE INC, 2025-09)
    INTRODUCTION: In search of disease-modifying treatments for the Niemann-Pick disease type C (NPC), this Phase II single-arm clinical trial evaluated the safety and efficacy of efavirenz, a reverse transcriptase inhibitor ...
  • Sharp increase in the incidence and severity of invasive Streptococcus pyogenes infections in children after the COVID-19 pandemic (2019-2023): A nationwide multicenter study 
    Cobo-Vázquez, Elvira; Aguilera-Alonso, David; Grandioso-Vas, David; Gamell, Anna; Rello-Saltor, Victoria; Oltra-Benavent, Manuel; Cervantes-Hernández, Eloisa; Sanz-Santaeufemia, Francisco; Carrasco-Colom, Jaime; Manzanares-Casteleiro, Ángela; Martín-Pedraz, Laura; Ramírez-de-Arellano, Eva; Falcon-Neira, Lola; Martínez-Campos, Leticia; Colino-Gil, Elena; Jiménez-Montero, Beatriz; Calavia, Olga; Hernández-Ventura, Anna; Del-Castillo-Navio, Elena; Matias-del-Pozo, Vanesa; Calle-Miguel, Laura; Soto, Beatriz; Fernández, Berta; Camil-Olteanu, Filip; Pareja-León, Marta; López-Segura, Nuria; Ara-Montojo, Fátima; Ruiz-Sáez, Beatriz; Calvo-Monge, Cristina; Sánchez-Codez, María; Reinoso, Teresa; Badillo, Katie; Vázquez, Carmen; Villalon, Pilar; Oteo-Iglesias, Jesús; Mellado-Sola, Isabel; Cercenado, Emilia; Blázquez-Gamero, Daniel; Menasalvas-Ruiz, Ana-Isabel; González-Abad, María-José; Guarch, Borja; Ibáñez-Alcalde, Mercedes; Carazo, Begoña; Lung, Mayli; Calvo, Cristina; Saavedra-Lozano, Jesús (ELSEVIER SCI LTD, 2025-10)
    OBJECTIVES: A global surge in pediatric invasive group A streptococcal infection (iGAS) was reported after autumn 2022. This study analyzed the epidemiology and severity of iGAS in Spain, comparing two periods; P1: ...
  • Severe Neutropenia in Infants With Congenital Cytomegalovirus on Antiviral Therapy 
    Papaevangelou, Vassiliki; Pedrero-Tome, Roberto; Syridou, Garyfallia; Baquero-Artigao, Fernando; Rodriguez-Molino, Paula; del Rosal, Teresa; Noguera-Julian, Antoni; Rios-Barnes, Maria; Fortuny, Claudia; Villaverde, Serena; Frick, Maria Antoinnette; Vallejo, Beatriz Alvarez; Soler-Palacin, Pere; Saavedra, Jesus; Karagiannidou, Sofia; Rincon, Elena; Busselo, Itziar Sota; Zuriarrain, Oihana Muga; Calderon, Elisenda Moliner; Tagarro, Alfredo; Malumbres, Maria; Colino, Elena; Llanos, Elisa Garrote; Ruiz, Ana Menasalvas; Mateos, Miguel Sanchez; Espuny, Xavier Bringue; Alonso-Ojembarrena, Almudena; Ferreras-Antolin, Laura; Perez, Irene Cuadrado; Posse, Ana Filgueira; Lyall, Hermione; Blazquez-Gamero, Daniel (LIPPINCOTT WILLIAMS & WILKINS, 2025-11)
    AIM: To describe European real-life experience of severe neutropenia (SN) during ganciclovir (GCV) and/or valganciclovir (VGCV) treatment in infants with congenital cytomegalovirus (cCMV) infection and identify risk factors ...
  • Impact of a community-based educational intervention on the burden and health-related quality of life of informal caregivers 
    Martínez-Melero, Inmaculada; Ruiz-García, María-Jesús; Ruiz-Merino, Guadalupe; García-Rubio, Ana (MOSBY-ELSEVIER, 2025-09)
    BACKGROUND: Caregiving for immobilized patients presents significant challenges that can profoundly impact the mental and physical health of informal caregivers. This study evaluates the impact of a community-based educational ...
  • Sex Differences in Children and Adolescents With Hypertrophic Cardiomyopathy 
    Norrish, Gabrielle; Hall, Kimberley; Field, Ella; Cervi, Elena; Boleti, Olga; Ziolkowska, Lidia; Olivotto, Iacopo; Passantino, Sylvia; Khraiche, Diala; Limongelli, Giuseppe; Weintraub, Robert-G; Anastasakis, Aris; Biagini, Elena; Ragni, Luca; Sarquella-Brugada, Georgia; Cesar, Sergi; Prendiville, Terrence; McLeod, Karen; Ilina, María; Baban, Anwar; Ojala, Tiina-H; Spentzou, Georgia; Bhole, Vinay; Gran, Feran; Brown, Elspeth; Delle-Donne, Grazia; Khodaghalian, Bernadette; Fernández, Adrián; Daubeney, Piers-E-F; Linter, Katie; Kubus, Peter; Uzun, Orhan; Bokenkamp, Regina; Raimondi, Francesca; Marrone, Chiara; Medrano, Constantio; González-López, Esther; Siles, Ana; Luczak-Wozniak, Katarzyna; Bharucha, Tara; Adwani, Satish; Klaassen, Sabine; Castro, Fernando-J; Guereta, Luis; Yamazawa, Hirokuni; Sinagra, Gianfranco; Popoiu, Anca; Perin, Francesca; Chana, B; De-Wilde, Hans; Rasmussen, Torsten-B; Mogensen, Jens; Mathur, Sujeev; Centeno, Fernando; Reinhardt, Zdenka; Barriales-Villa, Roberto; Kubo, Toru; Felice, Tiziana; Radulescu, Cristina; Schouvey, Sylvie; Chaker, Melissa; Kaski, Juan-Pablo (ELSEVIER, 2025-08)
    BACKGROUND: Sex differences have been described in adults with hypertrophic cardiomyopathy (HCM), but it is unknown if similar differences exist in childhood-onset disease. OBJECTIVES: This study aimed to investigate the ...
  • Comparative analysis of cryoballoon versus radiofrequency catheter ablation in atrial fibrillation patients with impaired left ventricular ejection fraction 
    Pongratz, J; Kuck, K-h; Metznerc, A; Hink, U; García-Alberola, Arcadio; Borchard, R; Noelker, G; Kuniss, M; Tilz, R-R; Schrickeli, J-W; Thornton, A; Thomas, D; Katus, H-A; Zahn, R; Spitzer, S; Souza, J-J; Brachmann, J; Tebbenjohanns, J; Wu, L-q; Obel, W-P; Groschup, G; Stellbrink, C; Chun, K-R-J; Gerds-Li, J-h; Stanley, A; Gopal, R-R; Lickfett, L; Lubinski, A; Schumacher, B; Steinwender, C; Franke, H-A; Ouarrak, T; Dorwarth, U; Senges, J; Hoffmann, E; Straube, F (ELSEVIER IRELAND LTD, 2025-08)
    BACKGROUND: In selected patients with atrial fibrillation (AF) and impaired left ventricular ejection fraction (LVEF), catheter ablation has been proposed for rhythm control. It is unclear, if cryoballoon (CBA) or ...
  • Lower rate of pancreatobiliary complications after sludge and microlithiasis pancreatitis compared to gallstone pancreatitis 
    Sirtl, Simon; Teodorescu, Bianca; Gilberg, Leónard; Schafer, Arlett; Beyer, Georg; Arnau, Anna; López-Guillén, Pablo; Martínez-Domínguez, Samuel-J; Abad-Baroja, Daniel; Oyon, Daniel; Ruiz-Belmonte, Lara-M; Tejedor-Tejada, Javier; Zapater, Raúl; Martín-Vicente, Noelia; Fernández-Esparcia, Pedro-José; Julián-Gomara, Ana-Belén; Sastre-Lozano, Violeta-María; Manzanares-García, Juan-José; Chivato-Martín-Falquina, Irene; Andrés-Pascual, Laura; Torres-Monclús, Nuria; Zaragoza-Velasco, Natividad; Rojo, Eukene; Lapena-Muñoz, Berta; Flores, Virginia; Díaz-Gómez, Arantxa; Canamares-Orbis, Pablo; Vinzo-Abizanda, Isabel; Carrasco, Natalia-Marcos; Pardo-Grau, Laura; García-Rayado, Guillermo; Millastre-Bocos, Judith; García-García-de-Paredes, Ana; Vaamonde-Lorenzo, María; Izaguirre-Arostegi, Arantzazu; Lozada-Hernández, Edgard-Efren; Velarde-Ruiz-Velasco, José-Antonio; Zorniak, Michal; de-Madaria, Enrique; Mayerle, Julia; Velamazan, Raúl (ELSEVIER SCIENCE INC, 2025-09)
    BACKGROUND AND AIMS: Cholecystectomy is recommended to prevent recurrence of biliary pancreatitis, but supporting evidence is limited for sludge- and microlithiasis-induced acute pancreatitis (AP). This study aimed to ...
  • MET pathway inhibition increases chemo-immunotherapy efficacy in small cell lung cancer 
    del Rey-Vergara, Raul; Galindo-Campos, Miguel Alejandro; Rocha, Pedro; Carpes, Marina; Martinez, Carlos; Masfarre, Laura; Menendez, Silvia; Quimis, Fabricio; Rossell, Adria; Inanez, Albert; Perez-Buira, Sandra; Rojo, Federico; Gimeno, Ramon; Isla, Dolores; Zugazagoitia, Jon; Blanco, Cristina Marti; Garcia-Campelo, Rosario; Moreno-Vega, Alberto; Leon-Mateos, Luis; Mellen, Angel Callejo; Park, Kwon-Sik; Heeke, Simon; Heymach, John V.; Taus, Alvaro; Paz-Ares, Luis; Rovira, Ana; Arriola, Edurne (CELL PRESS, 2025-07)
    The introduction of immunotherapy as a first-line treatment for advanced small cell lung cancer (SCLC) represents significant progress, yet there remains an opportunity to further improve patient outcomes. Hepatocyte growth ...
  • Practical guideline for major hereditary thrombophilia 
    Tang, Liang, V; Morange, Pierre-Emmanuel; Corral, Javier; Ntaios, Georgios; Spyropoulos, Alex C.; Lip, Gregory Y. H.; Douketis, James D. (CELL PRESS, 2025-06)
  • Annotation of biological samples data to standard ontologies with support from large language models 
    Riquelme-García, Andrea; Mulero-Hernández, Juan; Fernández-Breis, Jesualdo-Tomás (ELSEVIER, 2025)
    The semantic integration of biological data is hindered by the vast heterogeneity of data sources and their limited semantic formalization. A crucial step in this process is mapping data elements to ontological concepts, ...
  • A novel explainable AI framework for medical image classification integrating statistical, visual, and rule-based methods 
    Ullah, Naeem; Guzmán-Aroca, Florentina; Martínez-Álvarez, Francisco; De-Falco, Ivanoe; Sannino, Giovanna (ELSEVIER, 2025-10)
    Artificial intelligence and deep learning are powerful tools for extracting knowledge from large datasets, particularly in healthcare. However, their black-box nature raises interpretability concerns, especially in high-stakes ...
  • Moderate-to-severe hypercalcemia secondary to primary hyperparathyroidism refractory to conventional treatment (therapeutic management with denosumab): case report and literature review 
    Carpio-Salmerón, Manuel; Tebar-Caballero, Mariano; Marín-Martínez, Luis; Marco-Alacid, Cristian (AFRICAN FIELD EPIDEMIOLOGY NETWORK-AFENET, 2025)
    Severe hypercalcemia resistant to conventional medical treatment is a rare complication of primary hyperparathyroidism, and published information on the use of denosumab in patients with this condition is limited. This ...
  • Visceral leishmaniasis in heavily pretreated multiple myeloma patients a case series of 17 patients from the Mediterranean Coast of Spain 
    Monreal Bernal, Ana; Berenguer Piqueras, Mercedes; Ortiz Salvador, Pedro; Suarez Terron, Marina; Bataller Alfonso, Ana; Delgado Palacio, Soledad; Senent Peris, Maria Leonor; Roig Pellicer, Monica; Villalba Valenzuela, Ana; Benet Campos, Carmen; Espinosa Arnandi, Clara; Fernandez Poveda, Elena; Salido Fierez, Eduardo; Rodenas Quinonero, Isabel; de Arriba de la Fuente, Felipe; Ortiz Andrade, Jaime; Marco Ayala, Javier; Lozano, Maria L.; Ortuno, Francisco J. (TAYLOR & FRANCIS LTD, 2025-12-31)
    BACKGROUND AND OBJECTIVES: The introduction of novel therapies in multiple myeloma (MM) has significantly improved survival rates. However, their immunosuppressive nature predisposes patients to serious opportunistic ...
  • Quality of anticoagulation with vitamin K antagonists in Spain: A systematic review with meta-analysis of national registries 
    Rivera-Caravaca, José-Miguel; Menichelli, Danilo; Pastori, Daniele; Soler-Espejo, Eva; Esteve-Pastor, María-Asunción; Vivas, David; Roldan, Inmaculada; Anguita, Manuel; Ferreiro, José-Luis; Roldán-Schilling, Vanessa; Marín, Francisco (ELSEVIER ESPAÑA, 2025-09)
    BACKGROUND: Vitamin K antagonists (VKAs) depend on appropriate time in therapeutic range (TTR). We reviewed studies in Spain providing data on the quality of oral anticoagulation with VKA in atrial fibrillation (AF) patients, ...
  • Clinical Study of Biostimulation with Low-Power Diode Laser After Dental Extractions 
    Collado-Murcia, Yolanda; López-Jornet, Pía; Parra-Pérez, Francisco (MDPI, 2025-05-06)
    Introduction: The objective of the present work is to assess the efficacy of photobiomodulation (PBM) with respect to pain, inflammation, and healing after tooth extractions as compared with a sham treatment. Method: A ...
  • Exploring nurses' experiences with a school-located influenza vaccination program: A qualitative study in the region of Murcia, Spain 
    Perez Martin, Jaime; Zornoza Moreno, Matilde; Martinez Ruiz, Marina; Robles Manueco, Marta (TAYLOR & FRANCIS INC, 2025-12-31)
    A cross-sectional qualitative pilot study was designed to assess the nurses' perspectives regarding a school-located influenza vaccination pilot program. The program was developed during the 2022-2023 season in the Region ...
  • Isolation and characterization of extracellular vesicle subsets in donkey seminal plasma 
    Catalán, Jaime; Martínez-Díaz, Pablo; Parra, Ana; Bonet, Sergi; Yeste, Marc; Roca, Jordi; Barranco-Boada, María-Isabel; Miró, Jordi (ELSEVIER SCIENCE INC, 2025-09)
    Seminal plasma (SP), a fluid composed of secretions from the male genital tract, is rich in seminal extracellular vesicles (sEVs), nano-sized particles surrounded by a lipid bilayer membrane and loaded with functionally ...