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Repositorio Institucional en Ciencias de la Salud de la Región Murcia: Envíos recientes

  • SAMHD1 deficiency enhances macrophage-mediated clearance of Salmonella Typhimurium via NF-?B activation in zebrafish 
    Martínez-López, Alicia; Tyrkalska, Sylwia-D; Martínez-Morcillo, Francisco-J; Abenza-Olmos, Constantino; Lozano-Gil, Juan-Manuel; Candel, Sergio; Mulero, Víctoriano; García-Moreno, Diana (FRONTIERS MEDIA SA, 2025-04-25)
    INTRODUCTION: Mutations in the gene encoding the protein containing the sterile alpha motif and the HD domain (SAMHD1) have been implicated in the occurrence of type I interferonopathies. SAMHD1 is also involved in blocking ...
  • Frailty assessment in adults undergoing allogeneic hematopoietic cell transplantation: insights from a multicenter GETH-TC study to optimize outcomes and care 
    Queralt-Salas, María; Solano, María-Teresa; Baile-González, Mónica; Acera-Gómez, Marina; Fox, Laura; Pérez-Artigas, María-del-Mar; Santamaria, Ana; Quintela-González, María-del-Carmen; Sánchez-Salinas, Andrés; Salmerón-Camacho, Joaquina-María; Illana-alvaro, Veronica; Abdallahi-Lefdil, Zahra; Cornago-Navascues, Javier; Pardo, Laura; Fernández-Luis, Sara; Vega-Suárez, Leddy-Patricia; Villar, Sara; Beorlegui-Murillo, Patricia; Esquirol, Albert; Izquierdo-García, Isabel; Rodríguez-González, Sonia; Mussetti, Alberto; Lavilla-Rubira, Esperanza; López-Marín, Javier; Filaferro, Silvia; Cedillo, Ángel; Bento, Leyre; Sureda, Anna (FRONTIERS MEDIA SA, 2025-01-07)
    INTRODUCTION: This multicenter prospective study sponsored by the Grupo Español de Transplante Hematopoyético y Terapia Celular (GETH-TC) explores the use of frailty assessments in allo-HCT candidates. METHODS: Frailty was ...
  • The Gulliver syndrome: a conceptual framework to address therapeutic inertia in patients with borderline cardiovascular risk profiles (vol 12, 1652447, 2025) 
    López-Gil, José-Francisco; Abellán-Huerta, José; Abellán-Alemán, José (FRONTIERS MEDIA SA, 2025-11-06)
    [This corrects the article DOI: 10.3389/fcvm.2025.1652447.].
  • Editorial: Hypertension in obese women: gender-specific challenges and solutions 
    Cuevas, Santiago; Do-Carmo, Jussara-M; Maranon, Rodrigo-O (FRONTIERS MEDIA SA, 2025-02-04)
  • The Gulliver syndrome: a conceptual framework to address therapeutic inertia in patients with borderline cardiovascular risk profiles 
    López-Gil, José-Francisco; Abellán-Huerta, José; Abellán-Alemán, José (FRONTIERS MEDIA SA, 2025-08-14)
    We propose a novel clinical construct, the "Gulliver syndrome", to describe the scenario in which multiple, mildly elevated cardiovascular risk factors (CVRFs) coexist within an individual and together result in a significantly ...
  • Association between oral dysbiosis and Parkinson's disease: a systematic review 
    Murcia-Flores, Laura; Sánchez-García, Ana; Pecci-Lloret, María-Pilar; Rodríguez-Lozano, Francisco-Javier (FRONTIERS MEDIA SA, 2025-05-13)
    The oral cavity serves as the gateway to the human organism, hosting a diverse community of microorganisms that coexist in a state of symbiosis. Disruption of this balance leads to oral dysbiosis, a condition associated ...
  • Interplay of KIR2DL5, nitric oxide, and tobacco smoking in predisposition to bladder cancer 
    Ruiz-Lorente, Inmaculada; Gimeno-Arias, Lourdes; López-Abad, Alicia; López-Cubillana, Pedro; Fernández-Aparicio, Tomás; Asensio-Egea, Lucas-Jesús; Moreno-Avilés, Juan; Doñate-Íñiguez, Gloria; Guzmán-Martínez-Valls, Pablo-Luis; Server, Gerardo; Ferri-Ñíguez, Belén; Campillo, José-Antonio; Galindo, Francisco; Boix-Giner, Francisco; Martínez-Sánchez, María-Victoria; Martínez-Hernández, María-Dolores; Minguela-Puras, Alfredo (FRONTIERS MEDIA SA, 2025-09-04)
    INTRODUCTION: Tobacco smoking is the most significant risk factor for bladder cancer (BC), followed by other environmental and dietary exposures. However, major genetic determinants remain unidentified. The objective of ...
  • Immunolocalization and proteomic analyses of IZUMO1 in porcine spermatozoa 
    Hernández-Falco, Miranda; Sáez-Espinosa, Paula; López-Botella, Andrea; Robles-Gómez, Laura; García-Vázquez, Francisco-Alberto; Izquierdo-Rico, María-José; Llamas-López, Pedro-José; Gómez-Torres, María-José (FRONTIERS MEDIA SA, 2025-05-16)
    Reproduction is fundamental to breeding programs aimed at increasing productivity in swine industry. However, the application of in vitro embryo production in this species is limited because of the polyspermy. Therefore, ...
  • The co-inheritance of two ITGB3 variants with additive detrimental effects on platelets leads to variant Glanzmann thrombasthenia. 
    Arndt, Nina; Falcinelli, Emanuela; Zamora-Cánovas, Ana; Sánchez-Fuentes, Ana; Marín-Quílez, Ana; Nieto-Hernández, María-Del-Mar; Rivera, José; Gresele, Paolo; Bury, Loredana (FERRATA STORTI FOUNDATION, 2025-09-25)
  • A scoring system to predict life-threatening thromboischemic events in patients with acute promyelocytic leukemia: the PETHEMA/PALG study. 
    Rodríguez-Veiga, Rebeca; Gil, Cristina; Sobas, Marta; Torres-Miñana, Laura; Botella-Martínez, Carmen; de-la-Serna, Javier; Bernal, Teresa; Salamero, Olga; Otero, Cristina; Navarro-Vicente, Irene; de-Miguel, Carlos; Garrido, Ana; Vives, Susana; Bergua, Juan; Pérez-Encinas, Manuel; Algarra, Lorenzo; González-Campos, José; Caballero-Gómez, María-del-Mar; Prates, María-Virginia; Benavente, Celina; Tormo, Mar; Cervera, Marta; Fazio, Patricia; Amutio, María-Elena; García, Raimundo; Pomares, Helena; Vidriales, Belén; Serrano, Josefina; Amigo, María-Luz; Rubio, Vicente; Almela, Agata; Barrios, Manuel; Sossa-Melo, Claudia-Lucía; Paluszewska, Monika; Novo, Andrés; Gromek, Tomasz; Rodríguez-Macias, Gabriela; Oleksiuk, Jolanta; Lloret-Madrid, Pilar; Montesinos, Pau (FERRATA STORTI FOUNDATION, 2025-11-13)
    Acute promyelocytic leukemia (APL) is a highly curable leukemia characterized by life-threatening coagulopathy leading to hemorrhagic and thrombo-ischemic events. We analyzed the incidence, outcomes and risk-factors of ...
  • Use of second-line and beyond maintenance therapies in adult patients with primary immune thrombocytopenia in Europe: a parallel study of six prospective multicenter national registries 
    Moulis, Guillaume; Chen, Frederick; Carli, Giuseppe; Ghanima, Waleed; Trautmann-Grill, Karolin; Stauch, Thomas; Schifferli, Alexandra; Miah, Haroon; Rueter, Manuela; Ghiotto, Lisanna; Tomasello, Riccardo; Georgi, Annabell; Mcdonald, Vickie; Zaja, Francesco; Pettersen, Heidi-Hassel; Kuhne, Thomas; Lozano-Almela, María-Luisa; González-López, Tomas-Jose; Provan, Drew; Michel, Marc; Cooper, Nichola; Rodeghiero, Francesco (FERRATA STORTI FOUNDATION, 2025-06-26)
  • Cancer-related thrombosis: impact of biological sex on the risk of rethrombosis and bleeding 
    García-Adrián, Silvia; Iglesias-Pérez, Claudia; Carmona-Bayonas, Alberto; Ortega-Morán, Laura; Pérez, Jaime-Rubio; Martínez-del-Prado, Purificación; Martínez-de-Castro, Eva; Neria, Fernando; Fernández-Pérez, Isaura; García-de-Herreros, Marta; Carmona-Campos, Marta; García-Escobar, Ignacio; Balanya, Rut-Porta; Marrupe-González, David; Jiménez-Fonseca, Paula; Guirao-García, María-Esperanza; Sánchez-Cánovas, Manuel; Muñoz-Langa, José; Pérez-Segura, Pedro; Méndez-Vidal, M-José; Muñoz-Martín, Andrés-Jesús (FERRATA STORTI FOUNDATION, 2025-07)
    Patients with cancer have a higher risk of re-thrombosis and bleeding secondary to anticoagulant treatment than have individuals without cancer. Given the lack of specific clinical trials, the decision regarding the optimal ...
  • Recovery of Renal Function and Late Withdrawal of Hemodialysis in IgD Multiple Myeloma: A Case Report 
    Vigueras-Hernández, María-Rosa; Sirvent-Pedreño, Ana-Esther; Enriquez, Ricardo; Pérez-Pérez, Antonio; de-Arriba-de-la-Fuente, Felipe; Andreu-Muñoz, Alberto (SCIENTIFIC SCHOLAR LLC, 2025-10-08)
  • Female genital mutilation: Reflections from field experience for intercultural health training 
    González-Valverde, Francisco-Miguel (GOBIERNO DE NAVARRA, 2025-10-16)
  • Effectiveness of a training program in the approach to gender-based violence in emergency professionals: A quasi-experimental study 
    Adánez-Martínez, Gracia; Pérez-Cánovas, Carlos; Leal-Costa, César; Conesa-Ferrer, María-Belén; Díaz-Agea, José-Luis; Jiménez-Ruiz, Ismael (GOBIERNO DE NAVARRA, 2025-04-22)
    BACKGROUND: Health systems play a key role in the detection and management of gender-based violence. This study aimed to evaluate the effectiveness of a training program designed to enhance the knowledge, skills, and ...
  • School-based victimization of transgender youth: A qualitative study 
    Martín-Castillo, David; García-Arenas, José-Joaquín; Sánchez-Muñoz, María; Jiménez-Barbero, José-Antonio; Pastor-Bravo, María-del-Mar (GOBIERNO DE NAVARRA, 2025-08-19)
    BACKGROUND: Evidence indicates that transgender adolescents are at heightened risk of experiencing violence during their school years. This study aims to explore victimization experiences from the perspective of transgender ...
  • Association of Cutaneous Immune-related Adverse Events with Overall Survival and Progression-free Survival in Oncology Patients Receiving Immune Checkpoint Inhibitors: A Prospective Study of 189 Patients in a Spanish Tertiary Care Hospital 
    Juan-Carpena, Gloria; Martínez-Banaclocha, Natividad; Carlos-Palazon-Cabanes, Juan; Niveiro-de-Jaime, María; Betlloch-mas, Isabel; Blanes-Martínez, Mar (ACTA DERMATO-VENEREOLOGICA, 2025-01-03)
    Cutaneous immune-related adverse events (cirAEs) may be associated with tumoral response and survival in patients using immune checkpoint inhibitors, but this relationship remains unclear because previous reports on the ...
  • One-Year Evaluation of Paliperidone Palmitate 6-Monthly: Satisfaction and Perceived Effectiveness Among Patients, Relatives, and Clinicians 
    Manchado-Perero, Sofía; Rodríguez-Lorente, Ana; García-Pérez, Alba-María; García, Guillermo-Isidro; Forcén-Muñoz, Luis-Alberto; Ovejero, Santiago; Sáez-Povedano, Rocío; González-Galdámez, Ana-Luisa; Mata-Iturralde, Laura; Ramírez-Bonilla, Mariluz; Fuentes-Pérez, Paloma; Ovejas-Catalán, Claudia; Suárez-Pinilla, Paula; Fernández-Abascal-Puente, Blanca; Colmenares, Miguel-Omana; Campos-Navarro, María-Pilar; Baca-García, Enrique; Lara-Fernández, Ana; Benavente-López, Sergio; Raya-Platero, Alberto; Barberán-Navalon, Miguel; Sánchez-Alonso, Sergio; Vázquez-Bourgon, Javier; Pappa, Sofia; García-Carmona, Juan-Antonio (DOVE MEDICAL PRESS LTD, 2025-05)
    BACKGROUND: Patient satisfaction and perceived treatment effectiveness play a critical role in healthcare outcomes and overall well-being. Understanding patient experiences can help identify barriers to adherence and guide ...
  • Neurologists' Openness to Evidence-Based Innovation in Multiple Sclerosis Care: Individual and Structural Determinants 
    Monreal, Enric; Gómez-Ballesteros, Rocío; Meca-Lallana, Virginia; Caminero, Ana-B; Meca-Lallana, José-Eustasio; Martínez-Yelamos, Sergio; Landete, Lamberto; García-Domínguez, José-M; Agüera, Eduardo; García-Arcelay, Elena; Medrano, Nicolás; Villar, Luisa-M; Maurino, Jorge (DOVE MEDICAL PRESS LTD, 2025-07)
    PURPOSE: Integration of evidence-based innovations, such as serum neurofilament light chain (sNfL) measurement into routine practice represents a pivotal opportunity to advance personalized care in multiple sclerosis (MS) ...
  • Real-World Evidence on Joint Condition in Non-Severe Hemophilia A Patients: A Multicenter Study 
    Marco-Rico, Ana; Calvo-Villas, José-Manuel; López-Jaime, Francisco-José; Canaro-Hirnyk, María; Nieto-Hernández, María-del-Mar; Herrero-Martín, Sonia; Entrena-Urena, Laura; Marcellini-Antonio, Shally; Díaz-Jordan, Bolivar-L; Jurado-Herrera, Sergio; Pérez-González, Noelia-Florencia; García-Díaz, Covadonga; García-Candel, Faustino; Fernández-Bello, Ihosvany; Marco-Vera, Pascual (DOVE MEDICAL PRESS LTD, 2025-05)
    PURPOSE: Patients with non-severe hemophilia A (PwnSHA) may be at risk for joint damage (JD), yet data remain scarce. Our aim was to evaluate the joint condition in PwnSHA in a real-world setting. PATIENTS AND METHODS: A ...