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Repositorio Institucional en Ciencias de la Salud de la Región Murcia: Envíos recientes

  • Predictors of Response to Exclusive Enteral Nutrition in Newly Diagnosed Crohn's Disease in Children: PRESENCE Study from SEGHNP 
    Moriczi, Melinda; Pujol-Muncunill, Gemma; Martín-Masot, Rafael; Jiménez-Trevino, Santiago; Segarra-Canton, Oscar; Ochoa-Sangrador, Carlos; Pena-Quintana, Luis; González-Santana, Daniel; Rodríguez-Martínez, Alejandro; Rosell-Camps, Antonio; Armas, Honorio; Barrio, Josefa; González-de-Caldas, Rafael; Rodríguez-Salas, Mónica; Balmaseda-Serrano, Elena; Donat-Aliaga, Ester; Bodas-Pinedo, Andrés; Vaquero-Sosa, Esther; Vecino-López, Raquel; Solar-Boga, Alfonso; Moreno-Álvarez, Ana; Sánchez-Sánchez, Cesar; Tolin-Hernani, Mar; Gutiérrez-Junquera, Carolina; Martínon-Torres, Nazareth; Leis-Trabazo, María-Rosaura; Javier-Eizaguirre, Francisco; García-Peris, Mónica; Medina-Benitez, Enrique; Fernández-Caamano, Beatriz; Vegas-Álvarez, Ana-María; Crespo-Valderrabano, Laura; Alonso-Vicente, Carmen; Rubio-Santiago, Javier; Galera-Martínez, Rafael; García-Romero, Ruth; Ros-Arnal, Ignacio; Fernández-Cebrian, Santiago; Lorenzo-Garrido, Helena; Viada-Bris, Javier-Francisco; Velasco-Rodríguez-Belvis, Marta; Bartolome-Porro, Juan-Manuel; Blanco-Rodríguez, Miriam; Barros-García, Patricia; Botija, Gonzalo; Chicano-Marin, Francisco-José; La-Orden-Izquierdo, Enrique; Crehua-Gaudiza, Elena; Navas-López, Victor-Manuel; Martín-de-Carpi, Javier (MDPI, 2020-04)
    Exclusive enteral nutrition (EEN) has been shown to be more effective than corticosteroids in achieving mucosal healing in children with Crohn´s disease (CD) without the adverse effects of these drugs. The aims of this ...
  • Bi-allelic missense disease-causing variants in RPL3L associate neonatal dilated cardiomyopathy with muscle-specific ribosome biogenesis 
    Ganapathi, Mythily; Argyriou, Loukas; Martínez-Azorin, Francisco; Morlot, Susanne; Yigit, Gokhan; Lee, Teresa-M; Auber, Bernd; von-Gise, Alexander; Petrey, Donald-S; Thiele, Holger; Cyganek, Lukas; Sabater-Molina, María; Ahimaz, Priyanka; Cabezas-Herrera, Juan; Sorli-García, Moises; Zibat, Arne; Siegelin, Markus-D; Burfeind, Peter; Buchovecky, Christie-M; Hasenfuss, Gerd; Honig, Barry; Li, Yun; Iglesias, Alejandro-D; Wollnik, Bernd (SPRINGER, 2020-11)
    Dilated cardiomyopathy (DCM) belongs to the most frequent forms of cardiomyopathy mainly characterized by cardiac dilatation and reduced systolic function. Although most cases of DCM are classified as sporadic, 20-30% of ...
  • Hypothalamic Crh/Avp, Plasmatic Glucose and Lactate Remain Unchanged During Habituation to Forced Exercise 
    Toval, Ángel; Vicente-Conesa, Francisco; Martínez-Ortega, Paloma; Kutsenko, Yevheniy; Morales-Delgado, Nicanor; Garrigos, Daniel; Alonso, Antonia; Ribeiro-Do-Couto, Bruno; Popovic, Miroljub; Luis-Ferran, José (FRONTIERS MEDIA SA, 2020-05-15)
    It has been demonstrated that physical activity contributes to a healthier life. However, there is a knowledge gap regarding the neural mechanisms producing these effects. One of the keystones to deal with this problem is ...
  • Participant-funded clinical trials on rare diseases 
    Dal-Re, Rafael; Palau, Francesc; Guillén-Navarro, Encarna; Ayuso, Carmen (EDICIONES DOYMA S A, 2020-10)
    The development of medicines for certain rare diseases can be frustrated by lack of funding. In certain cases the patients themselves, or their relatives, occasionally fund the clinical trial in which they will be treated ...
  • Genetic Factors Involved in Cardiomyopathies and in Cancer 
    Sabater-Molina, María; Navarro-Penalver, Marina; Muñoz-Esparza, Carmen; Esteban-Gil, Ángel; Santos-Mateo, Juan-José; Gimeno, Juan-R (MDPI, 2020-06)
    Cancer therapy-induced cardiomyopathy (CCM) manifests as left ventricular (LV) dysfunction and heart failure (HF). It is associated withparticular pharmacological agents and it is typically dose dependent, but significant ...
  • Spatial-Temporal Signals and Clinical Indices in Electrocardiographic Imaging (I): Preprocessing and Bipolar Potentials 
    Caulier-Cisterna, Raul; Sanroman-Junquera, Margarita; Muñoz-Romero, Sergio; Blanco-Velasco, Manuel; Goya-Esteban, Rebeca; García-Alberola, Arcadi; Rojo-Álvarez, José-Luis (MDPI, 2020-06)
    During the last years, Electrocardiographic Imaging (ECGI) has emerged as a powerful and promising clinical tool to support cardiologists. Starting from a plurality of potential measurements on the torso, ECGI yields a ...
  • Allogeneic Bone Marrow Mesenchymal Stem Cell Transplantation in Tooth Extractions Sites Ameliorates the Incidence of Osteonecrotic Jaw-Like Lesions in Zoledronic Acid-Treated Rats 
    Rodríguez-Lozano, Francisco-Javier; Oñate-Sánchez, Ricardo-E; Gonzalvez-García, Mar; Valles-Bergada, Marta; Martínez, Carlos-M; Revilla-Nuin, Beatriz; Guerrero-Gironés, Julia; Moraleda, José-María; García-Bernal, David (MDPI, 2020-06)
    Medication-related osteonecrosis of the jaw (MRONJ) is defined as the exposed necrotic bone involving the maxillofacial structures in bisphosphonate treated patients, and the pathophysiology of this disease remains unclear. ...
  • The Role of the Gut Microbiome in Colorectal Cancer Development and Therapy Response 
    Sánchez-Alcoholado, Lidia; Ramos-Molina, Bruno; Otero, Ana; Laborda-Illanes, Aurora; Ordonez, Rafael; Medina, José-Antonio; Gómez-Millan, Jaime; Queipo-Ortuno, María-Isabel (MDPI, 2020-06)
    Colorectal cancer (CRC) is the third most common cancer worldwide and the leading cause of cancer-related deaths. Recently, several studies have demonstrated that gut microbiota can alter CRC susceptibility and progression ...
  • Spatial-Temporal Signals and Clinical Indices in Electrocardiographic Imaging (II): Electrogram Clustering and T-Wave Alternans 
    Caulier-Cisterna, Raul; Blanco-Velasco, Manuel; Goya-Esteban, Rebeca; Muñoz-Romero, Sergio; Sanroman-Junquera, Margarita; García-Alberola, Arcadi; Rojo-Álvarez, José-Luis (MDPI, 2020-06)
    During the last years, attention and controversy have been present for the first commercially available equipment being used in Electrocardiographic Imaging (ECGI), a new cardiac diagnostic tool which opens up a new field ...
  • TMEM95 is a sperm membrane protein essential for mammalian fertilization 
    Lamas-Toranzo, Ismael; Hamze, Julieta-G; Bianchi, Enrica; Fernández-Fuertes, Beatriz; Pérez-Cerezales, Serafin; Laguna-Barraza, Ricardo; Fernández-González, Raul; Lonergan, Pat; Gutiérrez-Adan, Alfonso; Wright, Gavin-J; Jiménez-Movilla, María; Bermejo-Álvarez, Pablo (ELIFE SCIENCES PUBLICATIONS LTD, 2020)
    The fusion of gamete membranes during fertilization is an essential process for sexual reproduction. Despite its importance, only three proteins are known to be indispensable for sperm-egg membrane fusion: the sperm proteins ...
  • Fish Oil Enriched Intravenous Lipid Emulsions Reduce Triglyceride Levels in Non-Critically Ill Patients with TPN and Type 2 Diabetes. A Post-Hoc Analysis of the INSUPAR Study 
    Abuin-Fernández, José; Tapia-Guerrero, María-José; López-Urdiales, Rafael; Herranz-Antolin, Sandra; García-Almeida, José-Manuel; García-Malpartida, Katherine; Ferrer-Gómez, Mercedes; Cancer-Minchot, Emilia; Luengo-Pérez, Luis-Miguel; Álvarez-Hernández, Julia; Aragon-Valera, Carmen; Ocon-Breton, Julia; García-Manzanares, Alvaro; Breton-Lesmes, Irene; Serrano-Aguayo, Pilar; Pérez-Ferre, Natalia; López-Gómez, Juan-José; Olivares-Alcolea, Joséfina; Arraiza-Irigoyen, Carmen; Tejera-Pérez, Cristina; Martínez-González, Jorge-Daniel; URíoste-Fondo, Ana; Abad-González, Ángel-Luis; Molina-Puerta, María-José; Zugasti-Murillo, Ana; Parra-Barona, Juan; López-Cobo, Irela; Olveira, Gabriel (MDPI, 2020-06)
    There are no studies that have specifically assessed the role of intravenous lipid emulsions (ILE) enriched with fish oil in people with diabetes receiving total parenteral nutrition (TPN). The objective of this study was ...
  • Activation of adenosine A3 receptor protects retinal ganglion cells from degeneration induced by ocular hypertension 
    Boia, Raquel; Salinas-Navarro, Manuel; Gallego-Ortega, Alejandro; Galindo-Romero, Caridad; Aires, Ines-D; Agudo-Barriuso, Marta; Ambrosio, Antonio-Francisco; Vidal-Sanz, Manuel; Santiago, Ana-Raquel (NATURE PUBLISHING GROUP, 2020-05-27)
    Glaucoma is a progressive chronic retinal degenerative disease and a leading cause of global irreversible blindness. This disease is characterized by optic nerve damage and retinal ganglion cell (RGC) death. The current ...
  • Durability of bioprosthetic aortic valves in patients under the age of 60years-rationale and design of the international INDURE registry 
    Meuris, Bart; Borger, Michael-A; Bourguignon, Thierry; Siepe, Matthias; Grabenwoger, Martín; Laufer, Gunther; Binder, Konrad; Polvani, Gianluca; Stefano, Pierluigi; Coscioni, Enrico; van-Leeuwen, Wouter; Demers, Philippe; Dagenais, Francois; Canovas, Sergio; Theron, Alexis; Langanay, Thierry; Roussel, Jean-Christian; Wendler, Olaf; Mariscalco, Giovanni; Pessotto, Renzo; Botta, Beate; Bramlage, Peter; De-Paulis, Ruggero (BMC, 2020-05-27)
    BACKGROUND: There is an ever-growing number of patients requiring aortic valve replacement (AVR). Limited data is available on the long-term outcomes and structural integrity of bioprosthetic valves in younger patients ...
  • Transcirculation Approach for Mechanical Thrombectomy in Acute Ischemic Stroke: A Multicenter Study and Review of the Literature 
    Roa, Jorge-A; Maud, Alberto; Jabbour, Pascal; Dabus, Guilherme; Pazour, Avery; Dandapat, Sudeepta; Ortega-Gutiérrez, Santiago; Paez-Granda, Diego; Kalousek, Vladimir; Hasan, David-M; Samaniego, Edgar-A (FRONTIERS MEDIA SA, 2020-05-07)
    Background: Transcirculation approaches, which consist of primary catheterization of a target artery from the contralateral side or opposite cerebral circulation, provide alternate endovascular routes when anterograde ...
  • Key Bacteria in the Gut Microbiota Network for the Transition between Sedentary and Active Lifestyle 
    Castellanos, Nazareth; Diez, Gustavo-G; Antúnez-Almagro, Carmen; Bressa, Carlo; Bailén, María; González-Soltero, Rocío; Pérez, Margarita; Larrosa, Mar (MDPI, 2020-05)
    Physical activity modifies the gut microbiota, exerting health benefits on the host; however, the specific bacteria associated with exercise are not yet known. In this work, we propose a novel method, based on hierarchical ...
  • Seminal Plasma Induces Overexpression of Genes Associated with Embryo Development and Implantation in Day-6 Porcine Blastocysts 
    Martínez, Cristina-A; Cambra, Josép-M; Gil, María-A; Parrilla, Inmaculada; Álvarez-Rodríguez, Manuel; Rodríguez-Martínez, Heriberto; Cuello, Cristina; Martínez, Emilio-A (MDPI, 2020-05)
    The infusion of boar seminal plasma (SP) before artificial insemination (AI) positively alters the expression of endometrial genes and pathways involved in embryo development. This study aimed to determine which transcriptome ...
  • Patient-Reported Outcomes in ATLAS and FLAIR Participants on Long-Acting Regimens of Cabotegravir and Rilpivirine Over 48 Weeks 
    Murray, Miranda; Antela, Antonio; Mills, Anthony; Huang, Jenny; Jaeger, Hans; Bernal-Morell, Enrique; Lombaard, Johan; Katner, Harold; Walmsley, Sharon; Khuong-Josses, Marie-Aude; Hudson, Krischan; Dorey, David; Griffith, Sandy; Spreen, William; Vanveggel, Simon; Shaefer, Mark; Margolis, David; Chounta, Vasiliki (SPRINGER/PLENUM PUBLISHERS, 2020-12)
    The phase 3 ATLAS and FLAIR studies demonstrated that maintenance with Long-Acting (LA) intramuscular cabotegravir and rilpivirine is non-inferior in efficacy to current antiretroviral (CAR) oral therapy. Both studies ...
  • Period of Boar Ejaculate Collection Contributes to the Yearly Intra-Male Variability of Seminal Plasma Cytokines 
    Padilla, Lorena; Lucas, Xiomara; Parrilla, Inmaculada; Pérez-Patiño, Cristina; Rodríguez-Martínez, Heriberto; Roca, Jordi; Barranco, Isabel (MDPI, 2020-05)
    The concentrations of cytokines in seminal plasma (SP) fluctuate over time in healthy males, weakening their practical usefulness as diagnostic tools. This study evaluated the relevance of intra-male variability in SP ...
  • Feasibility of implementing a preventive physical exercise programme recommended by general practitioners in cardiovascular risk patients: A pre-post comparison study 
    López-Román, Francisco-Javier; Tornel-Minarro, Francisca; Delsors-Merida-Nicolich, Eloisa; Fernández-López, Lourdes; Martínez-Ros, María-Teresa; García-Sánchez, Esther; López-Santiago, Asensio (TAYLOR & FRANCIS LTD, 2020)
    Background: Physical inactivity implies a significant individual and society health burden.Objectives: To assess the feasibility of implementing a preventive physical exercise (PE) programme for the general population and ...
  • Clinical-Evolutionary Staging System of Primary Open-Angle Glaucoma Using Optical Coherence Tomography 
    Parra-Blesa, Alfonso; Sánchez-Alberca, Alfredo; García-Medina, José-Javier (MDPI, 2020-05)
    BACKGROUND: Primary open-angle glaucoma (POAG) is considered one of the main causes of blindness. Detection of POAG at early stages and classification into evolutionary stages is crucial to blindness prevention. METHODS: ...