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Repositorio Institucional en Ciencias de la Salud de la Región Murcia: Envíos recientes

  • Editorial: The Parallel March of Asthma and Allergy in Childhood: A Multi-Perspective Approach 
    Caffarelli, Carlo; Priftis, Kostas; Mastrorilli, Carla; García-Marcos, Luis (FRONTIERS MEDIA SA, 2018-05-09)
  • What Are the Effects of a Mediterranean Diet on Allergies and Asthma in Children? 
    Castro-Rodríguez, José-A; García-Marcos, Luis (FRONTIERS MEDIA SA, 2017-04-21)
    This review updates the relationship between the adherence to Mediterranean diet (MedDiet) assessed by questionnaire and asthma, allergic rhinitis, or atopic eczema in childhood. It deals with the effect of MedDiet in ...
  • Rare Variants in 48 Genes Account for 42% of Cases of Epilepsy With or Without Neurodevelopmental Delay in 246 Pediatric Patients 
    Fernández-Marmiesse, Ana; Roca, Iria; Díaz-Flores, Felicitas; Cantarin, Veronica; Socorro-Pérez-Poyato, Ma; Fontalba, Ana; Laranjeira, Francisco; Quintans, Sofia; Moldovan, Oana; Felgueroso, Blanca; Rodríguez-Pedreira, Montserrat; Simon, Rogelio; Camacho, Ana; Quijada, Pilar; Ibáñez-Mico, Salvador; Rosario-Domingno, Ma; Benito, Carmen; Calvo, Rocío; Pérez-Cejas, Antonia; Llanos-Carrasco, Ma; Ramos, Feliciano; Luz-Couce, Ma; Luz-Ruiz-Falco, Ma; Gutiérrez-Solana, Luis; Martínez-Atienza, Margarita (FRONTIERS MEDIA SA, 2019-11-08)
    In order to characterize the genetic architecture of epilepsy in a pediatric population from the Iberian Peninsula (including the Canary Islands), we conducted targeted exome sequencing of 246 patients with infantile-onset ...
  • A New Perspective for the Training Assessment: Machine Learning-Based Neurometric for Augmented User's Evaluation 
    Borghini, Gianluca; Arico, Pietro; Di-Flumeri, Gianluca; Sciaraffa, Nicolina; Colosimo, Alfredo; Herrero, María-Trinidad; Bezerianos, Anastasios; Thakor, Nitish-V; Babiloni, Fabio (FRONTIERS MEDIA SA, 2017-06-13)
    Inappropriate training assessment might have either high social costs and economic impacts, especially in high risks categories, such as Pilots, Air Traffic Controllers, or Surgeons. One of the current limitations of the ...
  • Effect of Single and Combined Monochromatic Light on the Human Pupillary Light Response 
    Bonmati-Carrion, María-A; Hild, Konstanze; Isherwood, Cheryl-M; Sweeney, Stephen-J; Revell, Victoria-L; Madrid, Juan-A; Rol, María-A; Skene, Debra-J (FRONTIERS MEDIA SA, 2018-11-29)
    The pupillary light reflex (PLR) is a neurological reflex driven by rods, cones, and melanopsin-containing retinal ganglion cells. Our aim was to achieve a more precise picture of the effects of 5-min duration monochromatic ...
  • A Re-evaluation of the Anatomy of the Claustrum in Rodents and Primates-Analyzing the Effect of Pallial Expansion 
    Binks, Daniel; Watson, Charles; Puelles, Luis (FRONTIERS MEDIA SA, 2019-03-26)
    The components of the claustrum have been identified by gene expression in mice, but there is still uncertainty about the location of homologous components in primates. To aid interpretation of homologous elements between ...
  • Clinical Phenotypes Associated to Engrailed 2 Gene Alterations in a Series of Neuropediatric Patients 
    Carratala-Marco, Francisco; Andreo-Lillo, Patricia; Martínez-Morga, Marta; Escámez-Martínez, Teresa; Botella-López, Arancha; Bueno, Carlos; Martínez, Salvador (FRONTIERS MEDIA SA, 2018-08-10)
    The engrailed homeobox protein (EN) plays an important role in the regionalization of the neural tube. EN distribution regulates the cerebellum and midbrain morphogenesis, as well as retinotectal synaptogenesis. In humans, ...
  • Early Events in Retinal Degeneration Caused by Rhodopsin Mutation or Pigment Epithelium Malfunction: Differences and Similarities 
    Di-Pierdomenico, Johnny; García-Ayuso, Diego; Pinilla, Isabel; Cuenca, Nicolas; Vidal-Sanz, Manuel; Agudo-Barriuso, Marta; Villegas-Pérez, María-Paz (FRONTIERS MEDIA SA, 2017-03-06)
    To study the course of photoreceptor cell death and macro and microglial reactivity in two rat models of retinal degeneration with different etiologies. Retinas from P23H-1 (rhodopsin mutation) and Royal College of Surgeon ...
  • Helicobacter pylori Antibody Reactivities and Colorectal Cancer Risk in a Case-control Study in Spain 
    Fernández-de-Larrea-Baz, Nerea; Michel, Ángelika; Romero, Beatriz; Pérez-Gómez, Beatriz; Moreno, Víctor; Martín, Vicente; Dierssen-Sotos, Trinidad; Jiménez-Moleon, José-Juan; Castilla, Jesús; Tardon, Adonina; Ruiz, Irune; Peiro, Rosana; Tejada, Antonio; Chirlaque-López, María-Dolores; Butt, Julia-A; Olmedo-Requena, Rocío; Gómez-Acebo, Inés; Linares, Pedro; Boldo, Elena; Castells, Antoni; Pawlita, Michael; Castaño-Vinyals, Gemma; Kogevinas, Manolis; de-Sanjose, Silvia; Pollan, Marina; del-Campo, Rosa; Waterboer, Tim; Aragonés, Nuria (FRONTIERS MEDIA SA, 2017-05-29)
    Background: Several studies have suggested that Helicobacter pylori (H. pylori) infection is a risk factor for colorectal cancer (CRC), while others have not confirmed this hypothesis. This work aimed to assess the relation ...
  • Eosinophilic Esophagitis: Review and Update 
    Gómez-Torrijos, Elisa; González-Mendiola, Rosario; Alvarado, Manuela; Avila, Robledo; Prieto-García, Alicia; Valbuena, Teresa; Borja, Jesús; Infante, Sonsoles; Pilar-López, M; Marchan, Eva; Prieto, Patricia; Moro, Mar; Rosado, Ana; Saiz, Vanessa; Somoza, María-Luisa; Uriel, Olga; Vazquez, Ángelina; Mur, Pilar; Poza-Guedes, Paloma; Bartra, Joan (FRONTIERS MEDIA SA, 2018-10-09)
    Background: Eosinophilic esophagitis (EoE) was first described in the 1990s, showing an increasing incidence and prevalence since then, being the leading cause of food impaction and the major cause of dysphagia. Probably, ...
  • P2X7 receptor induces Tumor necrosis Factor-a converting enzyme activation and release to Boost TnF-ae Production 
    Barberá-Cremades, María; Gómez, Ana-I; Baroja-Mazo, Alberto; Martínez-Alarcón, Laura; Martínez, Carlos-M; de-Torre-Minguela, Carlos; Pelegrín, Pablo (FRONTIERS MEDIA SA, 2017-07-24)
    Tumor necrosis factor (TNF)-? is a major pro-inflammatory cytokine produced in response to toll-like receptor stimulation. TNF-? release is controlled by the activity of TNF-? converting enzyme (TACE) that cut membrane-bound ...
  • Zebra Fish Lacking Adaptive immunity Acquire an Antiviral Alert State Characterized by Upregulated Gene expression of Apoptosis, Multigene Families, and interferon-related Genes (vol 8, pg 121, 2017) 
    García-Valtanen, Pablo; Martínez-López, Alicia; López-Muñoz, Azucena; Bello-Pérez, Melissa; Medina-Gali, Regla-M; Ortega-Villaizan, María-del-Mar; Varela, Mónica; Figueras, Antonio; Mulero, Victoriano; Novoa, Beatriz; Estepa, Amparo; Coll, Julio (FRONTIERS MEDIA SA, 2017-06-13)
    [This corrects the article on p. 121 in vol. 8, PMID: 28243233.].
  • Zebra Fish Lacking Adaptive Immunity Acquire an Antiviral Alert State Characterized by Upregulated Gene Expression of Apoptosis, Multigene Families, and Interferon-Related Genes 
    García-Valtanen, Pablo; Martínez-López, Alicia; López-Muñoz, Azucena; Bello-Pérez, Melissa; Medina-Gali, Regla-M; Ortega-Villaizan, María-del-Mar; Varela, Mónica; Figueras, Antonio; Mulero, Victoriano; Novoa, Beatriz; Estepa, Amparo; Coll, Julio (FRONTIERS MEDIA SA, 2017-02-13)
    To investigate fish innate immunity, we have conducted organ and cell immune-related transcriptomic as well as immunohistologic analysis in mutant zebra fish (Danio rerio) lacking adaptive immunity (rag1(-/-)) at different ...
  • The NLRP3 and Pyrin Inflammasomes: Implications in the Pathophysiology of Autoinflammatory Diseases 
    de-Torre-Minguela, Carlos; Mesa-del-Castillo, Pablo; Pelegrín, Pablo (FRONTIERS MEDIA SA, 2017-01-27)
    Inflammasomes are multiprotein complexes that critically control different aspects of innate and adaptive immunity. Among them we could highlight the release of pro-inflammatory cytokines that induce and maintain the ...
  • Molecular epidemiology of an enterovirus A71 outbreak associated with severe neurological disease, Spain, 2016 
    González-Sanz, Rubén; Casas-Alba, Didac; Launes, Cristian; Muñoz-Almagro, Carmen; Montserrat-Ruiz-García, María; Alonso, Mercedes; González-Abad, María-José; Megias, Gregoria; Rabella, Nuria; del-Cuerpo, Margarita; Gozalo-Marguello, Mónica; González-Praetorius, Alejandro; Martínez-Sapina, Ana; Goyanes-Galan, María-José; Pilar-Romero, María; Calvo, Cristina; Anton, Andrés; Imaz, Manuel; Aranzamendi, Maitane; Hernández-Rodríguez, Agueda; Moreno-Docón, Antonio; Rey-Cao, Sonia; Navascues, Ana; Otero, Almudena; Cabrerizo, María (EUR CENTRE DIS PREVENTION & CONTROL, 2019-02-14)
    IntroductionEnterovirus A71 (EV-A71) is an emerging pathogen that causes a wide range of disorders including severe neurological manifestations. In the past 20 years, this virus has been associated with large outbreaks of ...
  • The management of active surveillance in prostate cancer: validation of the Canary Prostate Active Surveillance Study risk calculator with the Spanish Urological Association Registry 
    Borque-Fernando, Ángel; Rubio-Briones, José; Mariano-Esteban, Luis; Collado-Serra, Argimiro; Pallas-Costa, Yoni; López-González, Pedro-Ángel; Huguet-Pérez, Jorge; Ignacio-Sanz-Velez, José; Gil-Fabra, Jesús-Manuel; Gómez-Gómez, Enrique; Quicios-Dorado, Cristina; Fumado, Lluis; Martínez-Breijo, Sara; Soto-Villalba, Juan (IMPACT JOURNALS LLC, 2017-12-12)
    The follow up of patients on active surveillance requires to repeat prostate biopsies. Predictive models that identify patients at low risk of progression or reclassification are essential to reduce the number of unnecessary ...
  • Increasing TIMP3 expression by hypomethylating agents diminishes soluble MICA, MICB and ULBP2 shedding in acute myeloid leukemia, facilitating NK cell-mediated immune recognition 
    Baragano-Raneros, Aroa; Minguela-Puras, Alfredo; Rodríguez, Ramon-M; Colado, Enrique; Bernal, Teresa; Anguita, Eduardo; Vasco-Mogorron, Adela; Chaparro-Gil, Alberto; Vidal-Castineira, J-R; Márquez-Kisinousky, Leonardo; Díaz-Bulnes, Paula; Martínez-Marin, Amelia; García-Garay, María-Carmen; Suárez-Álvarez, Beatriz; López-Larrea, Carlos (IMPACT JOURNALS LLC, 2017-05-09)
    Acute myeloid leukemia (AML) is a disease with great morphological and genetic heterogeneity, which complicates its prognosis and treatment. The hypomethylating agents azacitidine (Vidaza®, AZA) and decitabine (Dacogen®, ...
  • Patient satisfaction, an indicator to consider in the colorectal cancer process 
    Esteban-Delgado, Pilar; Soria-Aledo, Víctor (ARAN EDICIONES, S A, 2019)
    Colorectal cancer (CRC) is one of the most relevant diseases worldwide because of its incidence, prevalence and mortalitye. It is the third most common tumor in men, after lung and prostate cancer, and the second most ...
  • Conflict of interest. Why is it important? 
    Cienfuegos, Javier-A; Pérez-Cuadrado-Martínez, Enrique (ARAN EDICIONES, S A, 2019)
    Scientific publications are the main medium for distributing scientific contributions, be they original studies, reviews, clinical guidelines, editorials or consensus statements promoted by scientific societies, and they ...
  • Twisting of sleeve gastrectomy: two ways of clinic presentation 
    Giménez-Francés, Clara; González-Valverde, F-Miguel; Albarracín-Marín-Blázquez, Antonio (ARAN EDICIONES, S A, 2019)
    Laparoscopic sleeve gastrectomy is an increasingly widespread bariatric surgical technique thanks to its good outcomes and apparent simplicity. However, complications may arise, including hemorrhage, gastric fistula, and ...