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Envíos recientes

Repositorio Institucional en Ciencias de la Salud de la Región Murcia: Envíos recientes

  • Beyond Surveillance Mutations: Long-Term Trends and Clinical Relevance of Transmitted HIV Drug Resistance in Spain (2007-2023) 
    Muñoz-Baez, Paloma; Illescas-López, Marta; de-Salazar, Adolfo; Falcés-Romero, Iker; Pinto, Adriana; Portilla, Irene; Masia, Mar; Peraire, Joaquim; Alemán-Valls, María-Remedios; Sanchiz, Marta; Iborra-Bendicho, María-Asunción; Baza, Begoña; Aguilera, Antonio; Olalla, Julian; Espinosa, Nuria; Iribarren, José-Antonio; Gisbert, Laura; Imaz, Arkaitz; Montero, Marta; Navarro-Marcotegui, María; Suárez-García, Inés; Riera, Melchor; Pérez-Elias, María-Jesús; Galán, Juan-Carlos; García-Fraile, Lucio-Jesus; Sanz, José; Ibarra-Ugarte, Sofía; Bernal-Morell, Enrique; Blanco, José-Ramon; Navarro, Gemma; Martínez-Madrid, Onofre; Viciana-Ramos, María-Isabel; Mohamen-Balghata, Mohamed-Omar; Delgado, Elena; Thompson, Michael-M; Moreno, Cristina; Fuentes, Ana; García, Federico (OXFORD UNIV PRESS, 2026-06-02)
    BACKGROUND: While surveillance drug resistance mutations (SDRMs) remain essential for monitoring transmitted drug resistance (TDR), the clinical impact of transmitted resistance for current first-line regimens has become ...
  • Colonoscopy versus biennial FIT screening: a post hoc sustained-strategy analysis of the COLONPREV Trial 
    Castells, Antoni; Quintero, Enrique; Chen, Hongruyu; Bujanda, Luis; Castan-Cameo, Susana; Cubiella, Joaquín; Díaz-Tasende, José; Lanas, Ángel; Ono-Ono, Akiko; Serra-Burriel, Miquel (BMJ PUBLISHING GROUP, 2026-06-10)
    BACKGROUND: Pragmatic colorectal cancer (CRC) screening trials compare colonoscopy with faecal immunochemical testing (FIT), but differences in adherence complicate interpretation of comparative outcomes. OBJECTIVE: To ...
  • HIV-1 APOBEC-context Mutations Detected by Next-Generation Sequencing in Plasma: Implications for Drug Resistance Interpretation 
    Illescas-López, Marta; Muñoz-Baez, Paloma; de-Salazar, Adolfo; Delgado, Rafael; Iborra-Bendicho, María-Asunción; Galán, Juan-Carlos; Carracedo, Raquel; Sigcha, Mayra; López-Causape, Carla; Fuentes, Ana; Aguilera, Antonio; Marco-Sánchez, Cristina; García, Federico (OXFORD UNIV PRESS, 2026-06-04)
    BACKGROUND & AIMS: APOBEC3-mediated cytidine deamination produces characteristic G?A substitutions in HIV genomes, classically described in proviral DNA but also detectable in plasma HIV-1 RNA using next-generation sequencing ...
  • Plasma signals of lung tumor promotion for molecular cancer prevention. 
    Pandya, Tej; Zagorulya, María; Leung, Michelle-M; Augustine, Marcellus; Liu, Lydia-Y; Leppa, Aino-Maija; Baruchel, Ulysse; Ng, Sin-Wi; Klockner, Tamara; Mugabo, Miriam; Griffen, Anthony-J; Blyuss, Oleg; Iliakis, Chrysante-S; Grenov, Amalie; Haase, Kerstin; Muller, David-C; Chan, Ka-Hung; Wu, Jincheng; Burk, Vernon-A; Wright, Neil; Le-Marois, Alix; Pazukhina, Ekaterina; Ward, Sophia; Slawinski, Hubert; Pelletier, Marc; Murphy, Cian; Park, Matthew-D; Snoeks, Thomas; Suárez-Bonnet, Alejandro; Priestnall, Simon-L; Chardas, Alexandros; Grieco, Charlotte; Archer, Ami; Celik, Alpkaan; Jiménez-Sánchez, Alejandro; Scott, Rachel; Zahed, Hana; Montegut, Lea; Meza, Rafael; Durney, Clinton-H; Lam, Stephen; Karasaki, Takahiro; Vermeulen, Roel-C-H; Xu, Huilei; Serrano-Fernández, Pablo; Crnogorac-Jurcevic, Tatjana; Menon, Usha; Apostolidou, Sophia; Zaikin, Alexey; Gunu, Richard; Whitwell, Harry-J; Huang, Zhe; Li, Zonglun; Hu, Xin; Zhu, Bo; Li, Liming; Chirlaque-López, María-Dolores; Guevara, Marcela; Kolijn, P-Martijn; Guenoun, Aghiles; Mookherjee, Neeloffer; Johansson, Mattias; Wang, Ziqiao; Chatterjee, Nilanjan; Chiu, Chao-Hua; Chen, Zhengming; Pe'er, Dana; Sahai, Erik; Freytag, Saskia; Wack, Andreas; Gunter, Marc-J; Merad, Miriam; Zhang, Jianjun; Carlsten, Christopher; Yang, Pan-Chyr; Chen, Hsuan-Yu; Platz, Elizabeth-A; LaFave, Lindsay-M; Smith-Byrne, Karl; Jamal-Hanjani, Mariam; Litchfield, Kevin; Nene, Nuno-R; McGranahan, Nicholas; Gronroos, Eva; Hill, William; Weeden, Clare-E; Swanton, Charles (ELSEVIER, 2026-06)
    Predicting lung cancer risk would enhance prevention trials. Although the Canakinumab Anti-inflammatory Thrombosis Outcome Study (CANTOS) trial demonstrated reduced lung cancer incidence with interleukin (IL)-1? inhibition, ...
  • Between trauma and resilience - an ecological model of the determinants of mental health among Ukrainian war refugees in Europe: a cross-sectional study. 
    Szkup, Malgorzata; Kotwas, Artur; Erjavec, Karmen; Krsnik, Sabina; Fedortsiv, Olha; Burbela, Emilia; Stanisavljevic, Sanja; Rousou, Elena; Kleszcz, Agnieszka; Fernandes, Rita; Mikla, Marzena; Charitou, Paraskevi; Karakiewicz, Beata (SPRINGER, 2026-06-01)
    BACKGROUND: The full-scale invasion of Ukraine has generated the largest refugee crisis in Europe since the Second World War, exposing civilians to trauma, displacement, and prolonged uncertainty. Refugees face stressors ...
  • Immersive virtual reality for assessing decision-making in mass casualty incident and tactical combat casualty care scenarios among military personnel 
    López-López, Carmen-Amalia; Semeraro, Federico; Ocampo-Cervantes, Ana-Belén; Pardo-Ríos, Manuel; Guillén-Martínez, Daniel; Sánchez-Gómez, Marina; Venero-Sánchez, Nereo; Mendoza-López, Miriam; Ivanov, Matin; Cerón-Madrigal, José-Joaquín; Botía-González, María; Alcazar-Artero, Petronila-Mireia (BMJ PUBLISHING GROUP, 2026-05-28)
    INTRODUCTION: Military personnel frequently act as first responders in complex tactical-medical scenarios where they must make critical decisions under pressure and coordinate with civilian emergency services. Traditional ...
  • Pharmacokinetic/Pharmacodynamic Modelling of Cefquinome in Lactating Sheep and Lactating Goats After Intravenous, Subcutaneous and Long-Acting Administrations 
    Cárceles-Rodríguez, Carlos-Mario; Fernández-Varon, Emilio; Bernal-Alcaraz, Cristina; Cárceles-García, Carlos; Moron-Romero, Rocío; Díaz-Villamarin, Xando; Muñoz-Rascon, Pilar; Serrano-Rodríguez, Juan-Manuel (MDPI, 2026-06-13)
    The pharmacokinetics (PK) and pharmacokinetic-pharmacodynamic (PK/PD) relationships of cefquinome in small ruminants remain incompletely characterized, particularly for long-acting (LA) formulations. This study evaluated ...
  • Kinematic Alignment in Total Knee Arthroplasty of Varus Knees Minimises Distal Ankle Compensatory Changes Compared with Mechanical Alignment 
    Moya-Angeler, Joaquín; Sánchez-Urgelles, Pablo; Marín-Martínez, Carmelo; van-Laarhoven, Simon-Nurettin; Innocenti, Matteo; Akkaya, Mustafa; Leggieri, Filippo; Klasan, Antonio; Lajara-Marco, Francisco; León-Muñoz, Vicente-Jesús (MDPI, 2026-06-17)
    Background/Objectives: Alignment philosophy in total knee arthroplasty (TKA) may affect joints beyond the knee. Mechanical alignment (MA) targets a neutral mechanical axis, whereas kinematic alignment (KA) aims to restore ...
  • Flexible Bronchoscopy in the Intensive Care Unit: Controversies, Clinical Applications, and the Expanding Role of Intensivists 
    Weerawarna, Thushira; Mishra, Rajesh; Tantray, Sumara; Bharti, Manish; Mehta, Atul; Bilaceroglu, Semra; Mishra, Gaurav; Jahan, Ahsina; Esquinas-Rodríguez, Antonio (MDPI, 2026-06-12)
    Background: Flexible bronchoscopy (FB) has long been integral to pulmonology, but its bedside role in the intensive care unit (ICU) is expanding. Despite a lack of high-level evidence, FB remains a pivotal tool for airway ...
  • Long-Term Adherence to Benralizumab and Sustained Clinical Benefits in Patients with Severe Eosinophilic Asthma: Insights from GALERNA, a Retrospective Real-World Study in Spain 
    García-Moguel, Ismael; Aguero-Calvo, Juan; Betancor-Pérez, Diana; Carretero-Gracia, José-Angel; Díaz-Campos, Rocio-Magdalena; Fernández-Martínez-de-Septien, Carmen; Gómez-Bastero-Fernández, Ana; Hernández-Galván, Yurena; Lloret-Queralto, Juan-Antonio; Lluch-Tortajada, Inmaculada; Malanda, Nuria-Marina; Martin-García, Cristina; Martínez-Mesa, Álvaro; Martínez-Moragon, Eva; Medina-Gallardo, Juan-Francisco; Padilla-Galo, Alicia; Pérez-Chica, Gerardo; Plasencia-García, Inmaculada; Prieto-Montano, Patricia; Puchaes-Manchon, Carolina; Romero-Ribate, David; Valverde-Monge, Marcela; Zamarro-Parra, María-Soledad; Sánchez-Trincado, José-Luis; Nuevo, Javier; Luzon, Elisa; Velasco-Garrido, José-Luis (MDPI, 2026-06-12)
    Background: The GALERNA study is a retrospective real-world observational study conducted across 21 hospitals in Spain, aiming to evaluate long-term clinical benefits and adherence to benralizumab in 255 adult patients ...
  • Allergic Diseases and Impaired Lung Function in Children Exposed and Unexposed to Artisanal Brick Production 
    Linares-Segovia, Benigno; Bermúdez-Pérez, Rocio-Stephanie; Monroy-Torres, Rebeca; Jiménez-Garza, Octavio-Alejandro; Amador-Licona, Norma; Guizar-Mendoza, Juan-M; del-Río-Hidalgo, Rodrigo-Francisco; Ortega-García, Juan-Antonio; Claudio, Luz (MDPI, 2026-05-25)
    BACKGROUND: During the firing stage of artisanal brick production, particulate matter and other pollutants are released into the air, to which children are particularly vulnerable. OBJECTIVE: To compare the frequency of ...
  • Long-Term Survival and Risk of Second Malignant Neoplasms Among Childhood Cancer Patients in 16 Provinces of Spain 
    Galceran, Jaume; Ameijide, Alberto; Jeghalef, Noura; Sánchez, Antonia; Guevara, Marcela; Bigorra, Jamnica; Gutiérrez, Pilar; Boone, An-L-D; Garrido, Montserrat; Álvarez, Xitama; Vizcaino, Ana; Martín, Isabel; Onaindia, Amaia; Sanclemente, Silvia; Trallero, Jan; Sánchez, María-José; Palacios, María-Isabel; Cleries, Ramon; Carulla, María (MDPI, 2026-06-18)
    BACKGROUND: Childhood cancer survivors have a higher risk of developing malignancies later in life compared with individuals of similar age in the general population. In Spain, population-based evidence on second malignant ...
  • Validation and Exploratory Refinement of the HFA-ICOS Score for Cardiovascular Risk in Proteasome Inhibitor-Treated Multiple Myeloma: Single-Center Retrospective Study 
    Pons-Fuster, Eduardo; Riquelme-Pérez, Alejandro; Shumbar, Vyacheslav; González-Ponce, Celia-María; Fernández-Ávila, Juan-José; Ramon-Martínez, Andrés; Moreno-Belmonte, María-José; Cabañas-Perianes, Valentín; Pascual-Figal, Domingo-Andrés; Díaz-Carrasco, María-Sacramento; Caro-Martínez, César (MDPI, 2026-06-12)
    Background: Proteasome inhibitors (PIs) are integral in multiple myeloma (MM) treatment but carry a substantial risk of cardiovascular adverse events (CVAEs). The Heart Failure Association-International Cardio-Oncology ...
  • Surgical Management and Therapeutic Strategy of Uterine Sarcoma According to Histological Subtype and Staging: Updated Review and Recommendations 
    Muñoz-Casares, Francisco-Cristobal; Gómez-Barbadillo, José; Álvarez-Álvarez, Rosa; Hindi, Nadia; Sebio, Ana; Lozano-Lominchar, Pablo; Fernández-Hernández, Juan-Ángel; Vasques, Hugo; Muñoz-Muñoz, Paula; Asencio-Pascual, José-Manuel (MDPI, 2026-06-08)
    BACKGROUND: Uterine sarcomas represent a small and heterogeneous subgroup of uterine malignancies (accounting for less than 5%), characterized by high biological aggressiveness, high recurrence rates, and diagnostic ...
  • Acute Moderate-Dose ?-Alanine Improves Exercise Efficiency via Bicarbonate-Related Mechanisms During a Cycling Time Trial 
    Muñoz-Carrillo, Juan-Carlos; Pérez-Pinero, Silvia; López-Román, Francisco-Javier; Luque-Rubia, Antonio-J; Ávila-Gandía, Vicente (MDPI, 2026-06-20)
    BACKGROUND: Research on the acute effects of ?-alanine supplementation has primarily focused on performance outcomes, with limited attention to the underlying physiological mechanisms. This study aimed to investigate the ...
  • Assessment of Two Commercial Serological Assays for the Diagnosis and Post-Treatment Follow-Up of Strongyloidiasis in a Cohort of Patients with Chagas Disease 
    Gil-Gallardo, Luis; Simón-Páez, Marina; Nieto-Martínez, Javier; Flores-Chávez, María-Delmans; Iborra-Bendicho, María-Asunción; Segovia-Hernández, Manuel (MDPI, 2026-06-12)
    Strongyloidiasis is a neglected tropical disease that frequently coexists with Chagas disease (CD) among individuals from Latin America. Serology is increasingly used for the diagnosis and post-treatment follow-up of ...
  • Health Outcomes of Patients with Distal Urea Cycle Disorders Detected by Newborn Screening: Data from the Spanish National Registry 
    Yahyaoui, Raquel; Quijada-Fraile, Pilar; Blasco-Alonso, Javier; Vives-Piñera, Inmaculada; Gil-Ortega, David; Couce, María-Luz; Sánchez-Pintos, Paula; García-Jiménez, M-Concepcion; Meavilla-Olivas, Silvia; García-Volpe, Camila; de-los-Santos-Mercedes, Mariela; García-Cazorla, Angels; Felipe-Rucian, Ana; Dougherty-de-Miguel, Lucy; Morais-López, Ana; Bergua-Martínez, Ana; Andrade-Guerrero, José-David; Stanescu, Sinziana; Belanger, Amaya; Gil-Campos, Mercedes; Comino-Monroy, María-José; Bellusci, Marcello; Pérez-Mohand, Patricia; Barrio-Carreras, Delia; Pérez, Belén; Martin-Hernández, Elena (MDPI, 2026-06-18)
    Urea cycle disorders (UCDs) are rare inherited metabolic diseases associated with toxic hyperammonemia, leading to severe neurological damage and early mortality. Early diagnosis of distal UCDs through newborn screening ...
  • Autologous Bone Versus Xenograft and Their Combination in Vertical Ridge Augmentation: An Analysis of Graft Resorption and Implant Survival-A Systematic Review 
    Otero-Cruz, Ana-Rosa; Pecci-Lloret, María-Pilar; Pérez-Guzman, Nuria; El-Akrout, Ali-El-Yahyaoui; Ruiz-Roca, Juan-Antonio (MDPI, 2026-05-25)
    Background: The integrity of the alveolar ridge is compromised by tooth loss or trauma, initiating chronic resorption that alters bone morphology. Vertical bone augmentation (VBA) is a complex procedure required to ...
  • Comparison of Color Stability Between PMMA and Graphene-Reinforced PMMA After Being Subjected to pH Changes and Coffee 
    Serrano-Belmonte, Ildefonso; Torne-Duran, Sergi; San-Nicolas-Sánchez, Javier; Pérez-Fernández, Virginia; Martínez-Canovas, Ascensión (MDPI, 2026-05-22)
    Background/Objectives: Provisional restorations are widely used in fixed prosthodontics, and polymethyl methacrylate (PMMA) remains one of the most commonly used materials. Discoloration during intraoral service may ...
  • Retrospective Evaluation of the Topical Use of 1% Amitriptyline in Patients with Burning Mouth Syndrome 
    Pérez-Parrella, Carmen-Steffani; Ruiz-Roca, Juan-Antonio; Pons-Fuster, Eduardo; López-Jornet, Pía (MDPI, 2026-05-22)
    Objective: The aim of this study was to explore the clinical response and tolerability of topical 1% amitriptyline in patients with burning mouth syndrome in a real-world clinical setting. Methodology: A retrospective ...