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Repositorio Institucional en Ciencias de la Salud de la Región Murcia: Envíos recientes

  • Alcohol Consumption and Risk of Parkinson's Disease: Data from a Large Prospective European Cohort 
    Peters, Susan; Gallo, Valentina; Vineis, Paolo; Middleton, Lefkos-T; Forsgren, Lars; Sacerdote, Carlotta; Sieri, Sabina; Kyrozis, Andreas; Chirlaque-López, María-Dolores; Zamora-Ros, Raul; Hansson, Oskar; Petersson, Jesper; Katzke, Verena; Kuehn, Tilman; Mokoroa, Olatz; Masala, Giovanna; Ardanaz, Eva; Panico, Salvatore; Bergmann, Manuela-M; Key, Timothy-J; Weiderpass, Elisabete; Ferrari, Pietro; Vermeulen, Roel (WILEY, 2020-07)
    BACKGROUND: Parkinson's disease (PD) etiology is not well understood. Reported inverse associations with smoking and coffee consumption prompted the investigation of alcohol consumption as a risk factor, for which evidence ...
  • Chemopreventive effect of pomegranate and cocoa extracts on ultraviolet radiation-induced photocarcinogenesis in SKH-1 mice 
    Gómez-García, Francisco-José; López-López, Antonia; Guerrero-Sánchez, Yolanda; Sánchez-Siles, Maríano; Martínez-Diaz, Francisco; Camacho-Alonso, Fabio (PUBLIC LIBRARY SCIENCE, 2020-04-30)
    Non-melanoma skin cancer (NMSC) has a high and increasing incidence all over the world. Solar radiation is the main aetiology for humans. Although most research into photocarcinogenesis uses UVB as a source of radiation, ...
  • Tracing the retina to analyze the integrity and phagocytic capacity of the retinal pigment epithelium 
    Valiente-Soriano, Francisco-Javier; Salinas-Navarro, Manuel; Di-Pierdomenico, Johnny; García-Ayuso, Diego; Lucas-Ruiz, Fernando; Pinilla, Isabel; Cuenca, Nicolas; Vidal-Sanz, Manuel; Villegas-Pérez, María-Paz; Agudo-Barriuso, Marta (NATURE PORTFOLIO, 2020-04-29)
    We have developed a new technique to study the integrity, morphology and functionality of the retinal neurons and the retinal pigment epithelium (RPE). Young and old control albino (Sprague-Dawley) and pigmented (Piebald ...
  • Patterns and predictors of low physical activity in patients with stable COPD: a longitudinal study 
    Sánchez-Martínez, María-Piedad; Bernabeu-Mora, Roberto; García-Vidal, José-Antonio; Benitez-Martínez, Josép; de-Oliveira-Sousa, Silvana-Loana; Medina-Mirapeix, Francesc (SAGE PUBLICATIONS LTD, 2020-03)
    BACKGROUND: Despite the frequency and negative impact of low physical activity among patients with chronic obstructive pulmonary disease (COPD), little is known about how it persists and remits over time or the factors ...
  • Changes in the Expression of Pre-Replicative Complex Genes in hTERT and ALT Pediatric Brain Tumors 
    Idilli, Aurora-Irene; Pagani, Francesca; Kerschbamer, Emanuela; Berardinelli, Francesco; Bernabé, Manuel; Cayuela, María-Luisa; Piazza, Silvano; Poliani, Pietro-Luigi; Cusanelli, Emilio; Mione, María-Caterina (MDPI, 2020-04)
    Background: The up-regulation of a telomere maintenance mechanism (TMM) is a common feature of cancer cells and a hallmark of cancer. Routine methods for detecting TMMs in tumor samples are still missing, whereas telomerase ...
  • Stability and Predictors of Poor 6-min Walking Test Performance over 2 Years in Patients with COPD 
    Sánchez-Martínez, María-Piedad; Bernabeu-Mora, Roberto; Martínez-González, Maríano; Gacto-Sánchez, Maríano; Martín-San-Agustin, Rodrigo; Medina-Mirapeix, Francesc (MDPI, 2020-04)
    Poor performance in the 6-min walk test (6MWT < 350 m) is an important prognostic indicator of mortality and risk of exacerbations in patients with chronic obstructive pulmonary disease (COPD). Little is known about the ...
  • Hypothalamic Pomc expression restricted to GABAergic neurons suppresses Npy overexpression and restores food intake in obese mice 
    Trotta, Milagros; Bello, Estefania-Pilar; Alsina, Ramiro; Tavella, María-Belén; Ferran, José-Luis; Rubinstein, Marcelo; Bumaschny, Viviana-Florencia (ELSEVIER, 2020-07)
    OBJECTIVE: Hypothalamic arcuate proopiomelanocortin (Arc-POMC) neurons are involved in different physiological processes such as the regulation of energy balance, glucose homeostasis, and stress-induced analgesia. Since ...
  • In search of common developmental and evolutionary origin of the claustrum and subplate 
    Bruguier, Hannah; Suárez, Rodrigo; Manger, Paul; Hoerder-Suabedissen, Anna; Shelton, Andrew-M; Oliver, David-K; Packer, Adam-M; Ferran, José-L; García-Moreno, Fernando; Puelles, Luis; Molnar, Zoltan (WILEY, 2020-12-01)
    The human claustrum, a major hub of widespread neocortical connections, is a thin, bilateral sheet of gray matter located between the insular cortex and the striatum. The subplate is a largely transient cortical structure ...
  • Intramuscular Injection of Bone Marrow Stem Cells in Amyotrophic Lateral Sclerosis Patients: A Randomized Clinical Trial 
    Geijo-Barrientos, Emilio; Pastore-Olmedo, Carlos; De-Mingo, Pedro; Blanquer, Miguel; Gómez-Espuch, Joaquin; Iniesta, Francisca; García-Iniesta, Natalia; García-Hernández, Ana; Martín-Estefania, Carlos; Barríos, Laura; Moraleda, José-María; Martínez, Salvador (FRONTIERS MEDIA SA, 2020-03-24)
    BACKGROUND: Preclinical studies suggest that stem cells may be a valuable therapeutic tool in amyotrophic lateral sclerosis (ALS). As it has been demonstrated that there are molecular changes at the end-plate during the ...
  • Maternal and Perinatal Outcomes Associated With Extremely High Values for the sFlt-1 (Soluble fms-Like Tyrosine Kinase 1)/PlGF (Placental Growth Factor) Ratio 
    Villalain, Cecilia; Herraiz, Ignacio; Valle, Leonor; Mendoza, Manel; Delgado, Juan-Luis; Vázquez-Fernández, María; Martínez-Uriarte, Juan; Melchor, Inigo; Caamina, Sara; Fernández-Oliva, Antoni; Villar, Olga-Patricia; Galindo, Alberto (WILEY, 2020-04)
    Background There is little knowledge about the significance of extremely high values (>655) for the ratio of sFlt-1 (soluble fms-like tyrosine kinase 1) to PlGF (placental growth factor). We aim to describe the time-to-delivery ...
  • Frailty transitions and associated clinical outcomes in patients with stable COPD: A longitudinal study 
    Bernabeu-Mora, Roberto; Oliveira-Sousa, Silvana-Loana; Sánchez-Martínez, Piedad; García-Vidal, José-Antonio; Gacto-Sánchez, Maríano; Medina-Mirapeix, Francesc (PUBLIC LIBRARY SCIENCE, 2020-04-03)
    BACKGROUND: Although frailty is a frequent occurrence in chronic obstructive pulmonary disease (COPD) patients, evidence on the frequency of frailty transition is scarce. AIMS: The present study aimed to describe the frailty ...
  • Subarachnoid haemorrhage with negative tomographic angiography without vasospasm: is it necessary to perform angiographic controls? 
    Paez-Granda, Diego (REVISTA DE NEUROLOGIA, 2020-04-16)
    INTRODUCTION: In about 15% of cases, the lesion causing subarachnoid haemorrhage (SAH) is not detectable by imaging studies, and some controversy exists as regards how the diagnosis should be performed in these patients. ...
  • Spanish real-world experience with fingolimod in relapsing-remitting multiple sclerosis patients: MS NEXT study 
    Barrero, Francisco; Mallada-Frechin, Javier; Martínez-Gines, María-Luisa; Eugenia-Marzo, María; Meca-Lallana, Virginia; Izquierdo, Guillermo; Ramon-Ara, José; Oreja-Guevare, Celia; Meca-Lallana, José; Forero, Lucia; Sánchez-Veram, Irene; Moreno, María-José (PUBLIC LIBRARY SCIENCE, 2020-04-02)
    PURPOSE: The objective of this study was to characterize the demographic and clinical profile of RRMS patients receiving fingolimod in Spain, and to evaluate drug effectiveness and safety in clinical practice. METHODS: ...
  • Coordinated Intervention of Microglial and Muller Cells in Light-Induced Retinal Degeneration 
    Di-Pierdomenico, Johnny; Martínez-Vacas, Ana; Hernández-Muñoz, Daniel; Gómez-Ramírez, Ana-M; Valiente-Soriano, Francisco-Javier; Agudo-Barriuso, Marta; Vidal-Sanz, Manuel; Villegas-Pérez, María-Paz; García-Ayuso, Diego (ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2020-03)
    PURPOSE: To analyze the role of microglial and Müller cells in the formation of rings of photoreceptor degeneration caused by phototoxicity. METHODS: Two-month-old Sprague-Dawley rats were exposed to light and processed ...
  • Salivary Biomarkers and Their Correlation with Pain and Stress in Patients with Burning Mouth Syndrome 
    López-Jornet, Pia; Castillo-Felipe, Candela; Pardo-Marin, Luis; Ceron, José-J; Pons-Fuster, Eduardo; Tvarijonaviciute, Asta (MDPI, 2020-04)
    OBJECTIVE: To evaluate a panel of salivary analytes involving biomarkers of inflammation, stress, immune system and antioxidant status in patients with burning mouth syndrome (BMS) and to study their relationship with ...
  • Photoprotection and Skin Pigmentation: Melanin-Related Molecules and Some Other New Agents Obtained from Natural Sources 
    Solano, Francisco (MDPI, 2020-04)
    Direct sun exposure is one of the most aggressive factors for human skin. Sun radiation contains a range of the electromagnetic spectrum including UV light. In addition to the stratospheric ozone layer filtering the most ...
  • Changes in individual and contextual socio-economic level influence on reproductive behavior in Spanish women in the MCC-Spain study 
    Gómez-Acebo, Ines; Dierssen-Sotos, Trinidad; Palazuelos, Camilo; Castano-Vinyals, Gemma; Pérez-Gómez, Beatriz; Amiano, Pilar; Fernández-Villa, Tania; Ardanaz, Eva; Suárez-Calleja, Claudia; Alguacil, Juan; Molina-Barcelo, Ana; Jiménez-Moleon, José-J; Molero, Jessica-Alonso; Roca-Barcelo, Aina; Chirlaque-López, María-Dolores; Fernández-Vázquez, José-Pedro; Molinuevo, Amaia; Aragonés, Nuria; Serra, María-Sala; Binefa, Gemma; Moreno, Victor; Pollan, Marina; Kogevinas, Manolis; Llorca, Javier (BMC, 2020-04-15)
    BACKGROUND: The association between socioeconomic level and reproductive factors has been widely studied. For example, it is well known that women with lower socioeconomic status (SES) tend to have more children, the age ...
  • New approach for estimating risk of miscarriage after chorionic villus sampling 
    Gil, M-M; Molina, F-S; Rodríguez-Fernández, M; Delgado, J-L; Carrillo, M-P; Jani, J; Plasencia, W; Stratieva, V; Maiz, N; Carretero, P; Lismonde, A; Chaveeva, P; Burgos, J; Santacruz, B; Zamora, J; De-Paco-Matallana, Catalina (WILEY, 2020-11)
    OBJECTIVE: To estimate the risk of miscarriage associated with chorionic villus sampling (CVS). METHODS: This was a retrospective cohort study of women attending for routine ultrasound examination at 11 + 0 to 13 + 6 weeks' ...
  • Aortic valve stenosis provides complementary information to bleeding risk scores in non-valvular atrial fibrillation patients initiating anticoagulation 
    Elvira-Ruiz, Gines; Caro-Martínez, Cesar; Flores-Blanco, Pedro-José; Cerezo-Manchado, Juan-José; Albendin-Iglesias, Helena; Lova-Navarro, Alejandro; Arregui-Montoya, Francisco; Muñoz-Franco, Francisca-María; García-Iniesta, Natalia; García-Alberola, Arcadio; Bailén-Lorenzo, José-Luis; Pascual-Figal, Domingo-Andrés; Manzano-Fernández, Sergio (TSINGHUA UNIV PRESS, 2020)
    BACKGROUND: The identification of modifiable bleeding risk factors may be of relevance. The aim is to evaluate if aortic stenosis (AS) provides additional information to bleeding risk scores for predicting major bleeding ...
  • Recommendations on management of the SARS-CoV-2 coronavirus pandemic (Covid-19) in kidney transplant patients 
    López, Verónica; Vázquez, Teresa; Alonso-Titos, Juana; Cabello, Mercedes; Alonso, Ángel; Beneyto, Isabel; Crespo, Marta; Diaz-Corte, Carmen; Franco, Antonio; González-Roncero, Francisco; Gutiérrez, Elena; Guirado, Luis; Jiménez, Carlos; Jironda, Cristina; Lauzurica, Ricardo; Llorente, Santiago; Mazuecos, Auxiliadora; Paul, Javier; Rodríguez-Benot, Alberto; Carlos-Ruiz, Juan; Sánchez-Fructuoso, Ana; Sola, Eugenia; Torregrosa, Vicente; Zarraga, Sofia; Hernández, Domingo (SOC ESPANOLA NEFROLOGIA DR RAFAEL MATESANZ, 2020-05)
    The SARS-CoV-2 (Covid-19) coronavirus pandemic is evolving very quickly and means a special risk for both immunosuppressed and comorbid patients. Knowledge about this growing infection is also increasing although many ...