Repositorio Institucional en Ciencias de la Salud de la Región Murcia: Envíos recientes

Mostrando ítems 61-80 de 3751

FENOMA Study: Achieving Full Control in Patients with Severe Allergic Asthma

Cabrejos, Sheila; Moreira, Ana; Ramírez, Andreina; Quirce, Santiago; Soto-Campos, Gregorio; Davila, Ignacio; Campo, Paloma (DOVE MEDICAL PRESS LTD, 2020)

INTRODUCTION: A Spanish real-world study in patients with severe persistent asthma who achieved asthma control after a one-year treatment with omalizumab highlighted the phenotypic heterogeneity of these patients (FENOMA ...
Effect of a Combination of Citrus Flavones and Flavanones and Olive Polyphenols for the Reduction of Cardiovascular Disease Risk: An Exploratory Randomized, Double-Blind, Placebo-Controlled Study in Healthy Subjects

Sánchez-Macarro, Maravillas; Martínez-Rodríguez, Juan-Pablo; Bernal-Morell, Enrique; Pérez-Pinero, Silvia; Victoria-Montesinos, Desiree; García-Muñoz, Ana-María; Canovas-García, Fernando; Castillo-Sánchez, Julian; López-Román, Francisco-Javier (MDPI, 2020-05)

A single-center, randomized, double-blind controlled trial was conducted to assess the efficacy of a food supplement based on a combination of grapefruit, bitter orange, and olive extracts administered for eight weeks (n ...
Verapamil and Alzheimer's Disease: Past, Present, and Future

Popovic, Natalija; Morales-Delgado, Nicanor; Vidal-Mena, David; Alonso, Antonia; Pascual-Martínez, María; Caballero-Bleda, María; Popovic, Miroljub (FRONTIERS MEDIA SA, 2020)

Verapamil is a phenylalkylamine class calcium channel blocker that for half a century has been used for the treatment of cardiovascular diseases. Nowadays, verapamil is also considered as a drug option for the treatment ...
Glaucomatous Maculopathy: Thickness Differences on Inner and Outer Macular Layers between Ocular Hypertension and Early Primary Open-Angle Glaucoma Using 8 x 8 Posterior Pole Algorithm of SD-OCT

García-Medina, José-Javier; del-Rio-Vellosillo, Mónica; Palazon-Cabanes, Ana; Pinazo-Durán, María-Dolores; Zanón-Moreno, Vicente; Villegas-Pérez, María-Paz (MDPI, 2020-05)

The purpose of this study was to compare the thickness of all inner and outer macular layers between ocular hypertension (OHT) and early primary open-angle glaucoma (POAG) using spectral domain optical coherence tomography ...
Use of Saliva for Diagnosis and Monitoring the SARS-CoV-2: A General Perspective

Ceron, José-J; Lamy, Elsa; Martínez-Subiela, Silvia; López-Jornet, Pia; Capela-Silva, Fernando; Eckersall, Peter-David; Tvarijonaviciute, Asta (MDPI, 2020-05)

In this report, updated information and future perspectives about the use of saliva as a sample for laboratory analysis of the Covid-19 are highlighted. Saliva can be used for the direct detection of the SARS-CoV-2 virus, ...
Antithrombin deficiency as a still underdiagnosed type of thrombophilia: a primer for internists

Bravo-Pérez, Carlos; de-la-Morena-Barrio, María-Eugenia; Vicente, Vicente; Corral, Javier (MEDYCYNA PRAKTYCZNA SP K SP ZOO, 2020)

Antithrombin is a key endogenous anticoagulant that also plays other roles in inflammation, immunity, and other processes. Congenital antithrombin deficiency is the most severe type of thrombophilia, yet characterized by ...
Frequency and Clinicopathological Profile Associated with BrafMutations in Patients with Advanced Melanoma in Spain

López-Martín, José-A; Arance-Fernández, Ana; Ríos-Martín, Juan-José; Hernández-Losa, Javier; Alos-Hernández, Lucía; Cerezuela-Fuentes, Pablo; Ortiz-Reina, Sebastian; Ortega-Izquierdo, Eugenia; Martí, Rosa-M; Soberino-García, Jesús; Ferrer-Fabrega, Berta; Rodríguez-Peralto, José-Luis (ELSEVIER SCIENCE INC, 2020-06)

Real-world data on BRAF mutation frequency in advanced melanoma are lacking in Spain. Moreover, data available on clinicopathological profile of patients with advanced BRAF-mutant melanoma are currently limited. This study ...
Inheritance of Refractive Error in Millennials

Pusti, Dibyendu; Benito, Antonio; Madrid-Valero, Juan-J; Ordonana, Juan-R; Artal, Pablo (NATURE PORTFOLIO, 2020-05-18)

Over the last decades, the prevalence of myopia has suddenly increased, and at this rate, half of the world's population will be myopic by the year 2050. Contemporary behavioural and lifestyle circumstances, along with ...
LacZ-reporter mapping of Dlx5/6 expression and genoarchitectural analysis of the postnatal mouse prethalamus

Puelles, Luis; Diaz, Carmen; Stuhmer, Thorsten; Ferran, José-L; Martínez-de-la-Torre, Margaret; Rubenstein, John-L-R (WILEY, 2021-02)

We present here a thorough and complete analysis of mouse P0-P140 prethalamic histogenetic subdivisions and corresponding nuclear derivatives, in the context of local tract landmarks. The study used as fundamental material ...
The Addition of Lactobacillus spp., Enrofloxacin or Doxycycline Negatively Affects the Viability of Mycoplasma bovis in Diluted Bovine Semen

García-Galan, Ana; Gómez-Martín, Ángel; Bataller, Esther; Gomis, Jesús; Sánchez, Antonio; Gadea, Joaquin; Vieira, Luis-Alberto; García-Rosello, Empar; De-la-Fe, Christian (MDPI, 2020-05)

Mycoplasma bovis is an important etiologic agent of bovine mycoplasmosis in cattle. Different transmission routes have been described, including those related to reproduction. The presence of mycoplasma in semen has led ...
Relationship of Zonulin with Serum PCSK9 Levels after a High Fat Load in a Population of Obese Subjects

Molina-Vega, María; Castellano-Castillo, Daniel; Sánchez-Alcoholado, Lidia; Plaza-Andrade, Isaac; Perera-Martín, Gabriel; Cabrera-Mulero, Amanda; Fernández-García, José-Carlos; Ramos-Molina, Bruno; Cardona, Fernando; Tinahones, Francisco-J (MDPI, 2020-05)

Despite the fact that circulating levels of proprotein convertase subtilisin/kexin type 9 (PCSK9) remain unchanged after fat load in healthy lean individuals, PCSK9 has been suggested to have a role in postprandial lipemia ...
The FXII c.-4T>C Polymorphism as a Disease Modifier in Patients With Hereditary Angioedema Due to the FXII p.Thr328Lys Variant

Corvillo, Fernando; de-la-Morena-Barrio, María-Eugenia; Marcos-Bravo, Carmen; López-Trascasa, Margarita; Vicente, Vicente; Emsley, Jonas; Caballero, Teresa; Corral, Javier; López-Lera, Alberto (FRONTIERS MEDIA SA, 2020)

BACKGROUND: Hereditary angioedema due to the Thr328Lys variant in the coagulation factor XII (HAE-FXII) affects mainly women in whom the symptomatology is dependent on high estrogen levels. Clinical variability and incomplete ...
Intussusceptive Angiogenesis and Peg-Socket Junctions between Endothelial Cells and Smooth Muscle Cells in Early Arterial Intimal Thickening

Diaz-Flores, Lucio; Gutiérrez, Ricardo; Pino-García, Ma; Gayoso, Sara; Luis-Carrasco, José; Diaz-Flores-Jr, Lucio; González-Gómez, Miriam; Francisco-Madrid, Juan (MDPI, 2020-11)

Angiogenesis in arterial intimal thickening (AIT) has been considered mainly in late AIT stages and only refers to sprouting angiogenesis. We assess angiogenesis during early AIT development and the occurrence of the ...
N-(2-mercaptopropionyl)-glycine enhances in vitro pig embryo production and reduces oxidative stress

Cambra, J-M; Martínez, C-A; Rodríguez-Martínez, H; Martínez, E-A; Cuello, C; Gil, M-A (NATURE PORTFOLIO, 2020)

This study evaluated the effects of different concentrations (1, 10, 25, 50, and 100 µM) of the antioxidant N-(2-mercaptopropionyl)-glycine (NMPG), during the culture of in vitro-fertilized porcine oocytes. While the highest ...
Late Eating Is Associated with Obesity, Inflammatory Markers and Circadian-Related Disturbances in School-Aged Children

Martínez-Lozano, Nuria; Tvarijonaviciute, Asta; Ríos, Rafael; Baron, Isabel; Scheer, Frank-A-J-L; Garaulet, Marta (MDPI, 2020-09)

Late eating has been shown to promote metabolic dysregulation and to be associated with obesity in adults. However, few studies have explored this association in children. We compared the presence of obesity, metabolic ...
Comprehensive Custom NGS Panel Validation for the Improvement of the Stratification of B-Acute Lymphoblastic Leukemia Patients

Montano, Adrian; Hernández-Sánchez, Jesús; Forero-Castro, Maribel; Matorra-Miguel, María; Lumbreras, Eva; Miguel, Cristina; Santos, Sandra; Ramírez-Maldonado, Valentina; Fuster, José-Luis; de-las-Heras, Natalia; García-de-Coca, Alfonso; Sierra, Magdalena; Davila, Julio; de-la-Fuente, Ignacio; Olivier, Carmen; Olazabal, Juan; Martínez, Joaquin; Vega-García, Nerea; González, Teresa; Hernández-Rivas, Jesús-María; Benito, Rocío (MDPI, 2020-09)

BACKGROUND: B-acute lymphoblastic leukemia (B-ALL) is a hematological neoplasm of the stem lymphoid cell of the B lineage, characterized by the presence of genetic alterations closely related to the course of the disease. ...
Computational Analysis of Clinical and Molecular Markers and New Theranostic Possibilities in Primary Open-Angle Glaucoma

Pinazo-Durán, María-D; García-Medina, José-Javier; Bolarin, José-M; Sanz-González, Silvia-M; Valero-Vello, Mar; Abellan-Abenza, Javier; Zanón-Moreno, Vicente; Moreno-Montanes, Javier (MDPI, 2020-09)

Primary open-angle glaucoma (POAG) is a paramount cause of irreversible visual disability worldwide. We focus on identifying clinical and molecular facts that may help elucidating the pathogenic mechanisms of the disease. ...
Bone marrow MSC from pediatric patients with B-ALL highly immunosuppress T-cell responses but do not compromise CD19-CAR T-cell activity

Zanetti, Samanta-Romina; Romecin, Paola-Alejandra; Vinyoles, Meritxell; Juan, Manel; Fuster, José-Luis; Camos, Mireia; Querol, Sergi; Delgado, Mario; Menéndez, Pablo (BMJ PUBLISHING GROUP, 2020)

BACKGROUND: Although adoptive transfer of CD19-directed chimeric antigen receptor (CAR) T-cells (CD19-CAR T-cells) achieves high rates of complete response in patients with B-cell acute lymphoblastic leukemia (B-ALL), ...
Barriers Perceived by Managers and Clinical Professionals Related to the Implementation of Clinical Practice Guidelines for Breastfeeding through the Best Practice Spotlight Organization Program

Ramos-Morcillo, Antonio-Jesús; Harillo-Acevedo, David; Armero-Barranco, David; Leal-Costa, Cesar; Moral-García, José-Enrique; Ruzafa-Martínez, María (MDPI, 2020-09)

International institutions facilitate the contact of health professionals to evidence-based recommendations for promoting exclusive breast feeding (BF). However, the achievement of good rates of exclusive BF is still far ...
Adverse event management in the TOURMALINE-MM3 study of post-transplant ixazomib maintenance in multiple myeloma

Kaiser, Martín; Beksac, Meral; Gulbrandsen, Nina; Schjesvold, Fredrik; Hajek, Roman; Moreau, Philippe; de-Arriba-de-la-Fuente, Felipe; Mateos, María-Victoria; West, Sharon; Spencer, Andrew; Rajkumar, S-Vincent; Suryanarayan, Kaveri; Czorniak, Michael; Li, Cong; Teng, Zhaoyang; Labotka, Richard; Dimopoulos, Meletios-A (SPRINGER, 2020-08)

The phase 3, double-blind, placebo-controlled TOURMALINE-MM3 study (NCT02181413) demonstrated improved progression-free survival with ixazomib maintenance versus placebo post autologous stem cell transplant (ASCT) in ...

Mostrando ítems 61-80 de 3751

Buscar en DSpace

Búsqueda avanzada

Listar

Todo RICSMUR

Envíos recientes

Repositorio Institucional en Ciencias de la Salud de la Regi&oacute;n Murcia: Envíos recientes

Buscar en DSpace

Listar

Todo RICSMUR

Mi cuenta

Repositorio Institucional en Ciencias de la Salud de la Región Murcia: Envíos recientes