The Zebrafish as an Emerging Model to Study DNA Damage in Aging, Cancer and Other Diseases

Cayuela-Fuentes, María-Luisa; Claes, Kathleen-B-M; Ferreira, Miguel-Godinho; Henriques, Catarina-Martins; van-Eeden, Fredericus; Varga, Mate; Vierstraete, Jeroen; Mione, María-Caterina

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03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla)
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dc.contributor.author	Cayuela-Fuentes, María-Luisa
dc.contributor.author	Claes, Kathleen-B-M
dc.contributor.author	Ferreira, Miguel-Godinho
dc.contributor.author	Henriques, Catarina-Martins
dc.contributor.author	van-Eeden, Fredericus
dc.contributor.author	Varga, Mate
dc.contributor.author	Vierstraete, Jeroen
dc.contributor.author	Mione, María-Caterina
dc.date.accessioned	2026-01-22T07:34:41Z
dc.date.available	2026-01-22T07:34:41Z
dc.date.issued	2019-01-10
dc.identifier.citation	Cayuela ML, Claes KBM, Ferreira MG, Henriques CM, Van Eeden F, Varga M, et al. The Zebrafish as an Emerging Model to Study DNA Damage in Aging, Cancer and Other Diseases. Front Cell Dev Biol. 10 de enero de 2019;6:178.
dc.identifier.issn	2296-634X
dc.identifier.uri	https://sms.carm.es/ricsmur/handle/123456789/23966
dc.description.abstract	Cancer is a disease of the elderly, and old age is its largest risk factor. With age, DNA damage accumulates continuously, increasing the chance of malignant transformation. The zebrafish has emerged as an important vertebrate model to study these processes. Key mechanisms such as DNA damage responses and cellular senescence can be studied in zebrafish throughout its life course. In addition, the zebrafish is becoming an important resource to study telomere biology in aging, regeneration and cancer. Here we review some of the tools and resources that zebrafish researchers have developed and discuss their potential use in the study of DNA damage, cancer and aging related diseases.
dc.language.iso	eng
dc.publisher	FRONTIERS MEDIA SA
dc.rights	Atribución/Reconocimiento-NoComercial-CompartirIgual 4.0 Internacional
dc.rights.uri	https://creativecommons.org/licenses/by-nc-sa/4.0/deed.es	*
dc.title	The Zebrafish as an Emerging Model to Study DNA Damage in Aging, Cancer and Other Diseases
dc.type	info:eu-repo/semantics/article
dc.identifier.pmid	30687705
dc.relation.publisherversion	https://www.frontiersin.org/article/10.3389/fcell.2018.00178/full
dc.type.version	info:eu-repo/semantics/publishedVersion
dc.identifier.doi	10.3389/fcell.2018.00178
dc.journal.title	Frontiers in Cell and Developmental Biology