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  • Feasibility of implementing a preventive physical exercise programme recommended by general practitioners in cardiovascular risk patients: A pre-post comparison study 
    López-Román, Francisco-Javier; Tornel-Minarro, Francisca; Delsors-Merida-Nicolich, Eloisa; Fernández-López, Lourdes; Martínez-Ros, María-Teresa; García-Sánchez, Esther; López-Santiago, Asensio (TAYLOR & FRANCIS LTD, 2020)
    Background: Physical inactivity implies a significant individual and society health burden.Objectives: To assess the feasibility of implementing a preventive physical exercise (PE) programme for the general population and ...
  • Aortic valve stenosis provides complementary information to bleeding risk scores in non-valvular atrial fibrillation patients initiating anticoagulation 
    Elvira-Ruiz, Gines; Caro-Martínez, Cesar; Flores-Blanco, Pedro-José; Cerezo-Manchado, Juan-José; Albendin-Iglesias, Helena; Lova-Navarro, Alejandro; Arregui-Montoya, Francisco; Muñoz-Franco, Francisca-María; García-Iniesta, Natalia; García-Alberola, Arcadio; Bailén-Lorenzo, José-Luis; Pascual-Figal, Domingo-Andrés; Manzano-Fernández, Sergio (TSINGHUA UNIV PRESS, 2020)
    BACKGROUND: The identification of modifiable bleeding risk factors may be of relevance. The aim is to evaluate if aortic stenosis (AS) provides additional information to bleeding risk scores for predicting major bleeding ...
  • Vault changes after cyclopentolate instillation in eyes with posterior chamber phakic intraocular lens 
    Gargallo-Martínez, Beatriz; García-Medina, José-Javier; Rubio-Velazquez, Elena; Fernandes, Paulo; Villa-Collar, Cesar; González-Meijome, José-M; Gutiérrez-Ortega, Ramon (NATURE PORTFOLIO, 2020)
    Posterior chamber phakic intraocular lens (pIOL) implantation is a common option for correcting moderate-to-high ocular refractive defects. Because this pIOL is implanted on ciliary sulcus, the distance between the back ...
  • Volumetric study of the maxillary sinus in patients with sinus pathology 
    Pérez-Sayans, Mario; Suárez-Quintanilla, Juan-A; Chamorro-Petronacci, Cintia-M; Suárez-Penaranda, José-M; López-Jornet, Pia; Gómez-García, Francisco; Guerrero-Sánchez, Yolanda (PUBLIC LIBRARY SCIENCE, 2020)
    OBJECTIVES: The aim of this study is 1) to obtain the area and volumes of the maxillary sinuses in patients affected by clinically unilateral sinus pathology by comparing the results to the contralateral sinus and 2) to ...
  • FENOMA Study: Achieving Full Control in Patients with Severe Allergic Asthma 
    Cabrejos, Sheila; Moreira, Ana; Ramírez, Andreina; Quirce, Santiago; Soto-Campos, Gregorio; Davila, Ignacio; Campo, Paloma (DOVE MEDICAL PRESS LTD, 2020)
    INTRODUCTION: A Spanish real-world study in patients with severe persistent asthma who achieved asthma control after a one-year treatment with omalizumab highlighted the phenotypic heterogeneity of these patients (FENOMA ...
  • N-(2-mercaptopropionyl)-glycine enhances in vitro pig embryo production and reduces oxidative stress 
    Cambra, J-M; Martínez, C-A; Rodríguez-Martínez, H; Martínez, E-A; Cuello, C; Gil, M-A (NATURE PORTFOLIO, 2020)
    This study evaluated the effects of different concentrations (1, 10, 25, 50, and 100 µM) of the antioxidant N-(2-mercaptopropionyl)-glycine (NMPG), during the culture of in vitro-fertilized porcine oocytes. While the highest ...
  • Sex and Time-of-Day Impact on Anxiety and Passive Avoidance Memory Strategies in Mice 
    Meseguer-Henarejos, Ana-Belén; Popovic, Natalija; Bokonjic, Dubravko; Morales-Delgado, Nicanor; Alonso, Antonia; Caballero-Bleda, María; Popovic, Miroljub (FRONTIERS MEDIA SA, 2020)
    In humans, anxiety and cognitive processes are age, gender, and time of day dependent. The purpose of the present study was to assess whether the time of day and sex have an influence on anxiety and emotional memory in ...
  • Antithrombin deficiency as a still underdiagnosed type of thrombophilia: a primer for internists 
    Bravo-Pérez, Carlos; de-la-Morena-Barrio, María-Eugenia; Vicente, Vicente; Corral, Javier (MEDYCYNA PRAKTYCZNA SP K SP ZOO, 2020)
    Antithrombin is a key endogenous anticoagulant that also plays other roles in inflammation, immunity, and other processes. Congenital antithrombin deficiency is the most severe type of thrombophilia, yet characterized by ...
  • The economic benefits of increasing breastfeeding rates in Spain 
    Quesada, Juan-Antonio; Mendez, Ildefonso; Martín-Gil, Rocío (BMC, 2020)
    BACKGROUND: Interventions aimed at promoting breastfeeding rates are among the most effective possible health policies available, with an estimated return of US$35 per dollar invested. Indeed, some authors found that a 10% ...
  • The FXII c.-4T>C Polymorphism as a Disease Modifier in Patients With Hereditary Angioedema Due to the FXII p.Thr328Lys Variant 
    Corvillo, Fernando; de-la-Morena-Barrio, María-Eugenia; Marcos-Bravo, Carmen; López-Trascasa, Margarita; Vicente, Vicente; Emsley, Jonas; Caballero, Teresa; Corral, Javier; López-Lera, Alberto (FRONTIERS MEDIA SA, 2020)
    BACKGROUND: Hereditary angioedema due to the Thr328Lys variant in the coagulation factor XII (HAE-FXII) affects mainly women in whom the symptomatology is dependent on high estrogen levels. Clinical variability and incomplete ...
  • Cardiac, renal and uterine hemodynamics changes throughout pregnancy in rats with a prolonged high fat diet from an early age 
    Oltra, Lidia; Reverte, Virginia; Tapia, Antonio; Moreno, Juan-M; Salazar, Francisco-J; Llinas, María-T (PUBLIC LIBRARY SCIENCE, 2020)
    OBJECTIVE: To examine whether the cardiac, renal and uterine physiological hemodynamic changes during gestation are altered in rats with an early and prolonged exposure to a high fat diet (HFD). METHODS: Arterial pressure ...
  • Bone marrow MSC from pediatric patients with B-ALL highly immunosuppress T-cell responses but do not compromise CD19-CAR T-cell activity 
    Zanetti, Samanta-Romina; Romecin, Paola-Alejandra; Vinyoles, Meritxell; Juan, Manel; Fuster, José-Luis; Camos, Mireia; Querol, Sergi; Delgado, Mario; Menéndez, Pablo (BMJ PUBLISHING GROUP, 2020)
    BACKGROUND: Although adoptive transfer of CD19-directed chimeric antigen receptor (CAR) T-cells (CD19-CAR T-cells) achieves high rates of complete response in patients with B-cell acute lymphoblastic leukemia (B-ALL), ...
  • TMEM95 is a sperm membrane protein essential for mammalian fertilization 
    Lamas-Toranzo, Ismael; Hamze, Julieta-G; Bianchi, Enrica; Fernández-Fuertes, Beatriz; Pérez-Cerezales, Serafin; Laguna-Barraza, Ricardo; Fernández-González, Raul; Lonergan, Pat; Gutiérrez-Adan, Alfonso; Wright, Gavin-J; Jiménez-Movilla, María; Bermejo-Álvarez, Pablo (ELIFE SCIENCES PUBLICATIONS LTD, 2020)
    The fusion of gamete membranes during fertilization is an essential process for sexual reproduction. Despite its importance, only three proteins are known to be indispensable for sperm-egg membrane fusion: the sperm proteins ...
  • Hospital Pharmacy Compounding against COVID-19 pandemic 
    Alonso-Herreros, José-María; Berisa-Prado, Silvia; Canete-Ramírez, Carme; Davila-Pousa, Carmen; Flox-Benitez, María-del-Pilar; Ladron-de-Guevara-García, Margarita; López-Cabezas, Carmen; Martín-de-Rosales-Cabrera, Ana-María; Ramos-Martínez, Beatriz (ELSEVIER SCIENCE INC, 2020)
    As in other areas of the health system, COVID-19 has had a dramatic impact on  hospital compounding. This area has faced numerous challenges, including the  shortage of frequent-use products (hydroalcoholic solutions, lo ...
  • Verapamil and Alzheimer's Disease: Past, Present, and Future 
    Popovic, Natalija; Morales-Delgado, Nicanor; Vidal-Mena, David; Alonso, Antonia; Pascual-Martínez, María; Caballero-Bleda, María; Popovic, Miroljub (FRONTIERS MEDIA SA, 2020)
    Verapamil is a phenylalkylamine class calcium channel blocker that for half a century has been used for the treatment of cardiovascular diseases. Nowadays, verapamil is also considered as a drug option for the treatment ...
  • Patterns and predictors of low physical activity in patients with stable COPD: a longitudinal study 
    Sánchez-Martínez, María-Piedad; Bernabeu-Mora, Roberto; García-Vidal, José-Antonio; Benitez-Martínez, Josép; de-Oliveira-Sousa, Silvana-Loana; Medina-Mirapeix, Francesc (SAGE PUBLICATIONS LTD, 2020-03)
    BACKGROUND: Despite the frequency and negative impact of low physical activity among patients with chronic obstructive pulmonary disease (COPD), little is known about how it persists and remits over time or the factors ...
  • Will neurological care change over the next 5 years due to the COVID-19 pandemic? Key informant consensus survey 
    Matias-Guiu, J; Matias-Guiu, J-A; Álvarez-Sabin, J; Ramon-Ara, J; Arenillas, J; Casado-Naranjo, I; Castellanos, M; Jiménez-Hernández, M-D; Lainez-Andres, J-M; Moral, E; Morales, A; Rodríguez-Antiguedad, A; Segura, T; Serrano-Castro, P; Diez-Tejedor, E (ELSEVIER ESPANA SLU, 2020-04)
    INTRODUCTION: The COVID-19 pandemic will give rise to long-term changes in neurological care, which are not easily predictable. MATERIAL AND METHODS: A key informant survey was used to enquire about the changes expected ...
  • Predictors of Response to Exclusive Enteral Nutrition in Newly Diagnosed Crohn's Disease in Children: PRESENCE Study from SEGHNP 
    Moriczi, Melinda; Pujol-Muncunill, Gemma; Martín-Masot, Rafael; Jiménez-Trevino, Santiago; Segarra-Canton, Oscar; Ochoa-Sangrador, Carlos; Pena-Quintana, Luis; González-Santana, Daniel; Rodríguez-Martínez, Alejandro; Rosell-Camps, Antonio; Armas, Honorio; Barrio, Josefa; González-de-Caldas, Rafael; Rodríguez-Salas, Mónica; Balmaseda-Serrano, Elena; Donat-Aliaga, Ester; Bodas-Pinedo, Andrés; Vaquero-Sosa, Esther; Vecino-López, Raquel; Solar-Boga, Alfonso; Moreno-Álvarez, Ana; Sánchez-Sánchez, Cesar; Tolin-Hernani, Mar; Gutiérrez-Junquera, Carolina; Martínon-Torres, Nazareth; Leis-Trabazo, María-Rosaura; Javier-Eizaguirre, Francisco; García-Peris, Mónica; Medina-Benitez, Enrique; Fernández-Caamano, Beatriz; Vegas-Álvarez, Ana-María; Crespo-Valderrabano, Laura; Alonso-Vicente, Carmen; Rubio-Santiago, Javier; Galera-Martínez, Rafael; García-Romero, Ruth; Ros-Arnal, Ignacio; Fernández-Cebrian, Santiago; Lorenzo-Garrido, Helena; Viada-Bris, Javier-Francisco; Velasco-Rodríguez-Belvis, Marta; Bartolome-Porro, Juan-Manuel; Blanco-Rodríguez, Miriam; Barros-García, Patricia; Botija, Gonzalo; Chicano-Marin, Francisco-José; La-Orden-Izquierdo, Enrique; Crehua-Gaudiza, Elena; Navas-López, Victor-Manuel; Martín-de-Carpi, Javier (MDPI, 2020-04)
    Exclusive enteral nutrition (EEN) has been shown to be more effective than corticosteroids in achieving mucosal healing in children with Crohn´s disease (CD) without the adverse effects of these drugs. The aims of this ...
  • Changes in the Expression of Pre-Replicative Complex Genes in hTERT and ALT Pediatric Brain Tumors 
    Idilli, Aurora-Irene; Pagani, Francesca; Kerschbamer, Emanuela; Berardinelli, Francesco; Bernabé, Manuel; Cayuela, María-Luisa; Piazza, Silvano; Poliani, Pietro-Luigi; Cusanelli, Emilio; Mione, María-Caterina (MDPI, 2020-04)
    Background: The up-regulation of a telomere maintenance mechanism (TMM) is a common feature of cancer cells and a hallmark of cancer. Routine methods for detecting TMMs in tumor samples are still missing, whereas telomerase ...
  • Stability and Predictors of Poor 6-min Walking Test Performance over 2 Years in Patients with COPD 
    Sánchez-Martínez, María-Piedad; Bernabeu-Mora, Roberto; Martínez-González, Maríano; Gacto-Sánchez, Maríano; Martín-San-Agustin, Rodrigo; Medina-Mirapeix, Francesc (MDPI, 2020-04)
    Poor performance in the 6-min walk test (6MWT < 350 m) is an important prognostic indicator of mortality and risk of exacerbations in patients with chronic obstructive pulmonary disease (COPD). Little is known about the ...

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