Repositorio Dspace

Envíos recientes

03.01. Investigación y comunicación científica: Envíos recientes

  • Circulating Osteopontin and Prediction of Hepatocellular Carcinoma Development in a Large European Population 
    Stepien, Magdalena; Jenab, Mazda; Duarte-Salles, Talita; Misra, Sandeep; Beretta, Laura; Plymoth, Amelie; Muller, David; Overvad, Kim; Olsen, Anja; Tjonneland, Anne; Baglietto, Laura; Severi, Gianluca; Boutron-Ruault, Marie-Christine; Turzanski-Fortner, Renee; Kaaks, Rudolf; Boeing, Heiner; Aleksandrova, Krasimira; Trichopoulou, Antonia; Lagiou, Pagona; Bamia, Christina; Pala, Valeria; Palli, Domenico; Mattiello, Amalia; Naccarati, Alessio; Gunter, Marc-J; Cross, Amanda-J; Riboli, Elio; Bueno-de-Mesquita, H-B(as); Peeters, Petra-H; Weiderpass, Elisabete; Quiros, J-Ramon; Agudo, Antonio; Sánchez-Cantalejo, Emilio; Ardanaz, Eva; Gavrila-Chervase, Diana; Werner, Marten; Hemmingsson, Oskar; Ohlsson, Bodil; Sjoberg, Klas; Wareham, Nicholas-J; Khaw, Kay-Tee; Bradbury, Kathryn-E; Hainaut, Pierre; Tumino, Rosario; Dorronsoro, Miren (2016-09-01)
    We previously identified osteopontin (OPN) as a promising marker for the early detection of hepatocellular carcinoma (HCC). In this study, we investigated the association between prediagnostic circulating OPN levels and ...
  • Generation of induced pluripotent stem cells (iPSCs) from a Bernard-Soulier syndrome patient carrying a W71R mutation in the GPIX gene 
    López-Onieva, Lourdes; Montes, Rosa; Lamolda, Mar; Romero, Tamara; Ayllon, Veronica; Ramos-Mejia, Veronica; Real, Pedro-J; Lozano-Almela, María-Luisa; Vicente, Vicente; Rivera, José (2016-05)
    We generated an induced pluripotent stem cell (iPSC) line from a Bernard-Soulier Syndrome (BSS) patient carrying the mutation p.Trp71Arg in the GPIX locus (BSS1-PBMC-iPS4F4). Peripheral blood mononuclear cells (PBMCs) were ...
  • Tissue-specific regulation of potassium homeostasis by high doses of cationic amino acids 
    del-Río-García, Jesús; López-García, Carlos; Lambertos, Ana; Cremades, Asunción; Peñafiel, Rafael (2016-12)
    The administration of l-arginine hydrochloride has been used for testing pituitary secretion in humans, and as an experimental model for induction of acute pancreatitis in rats and mice. Whereas in the first case, the ...
  • Heparanase Activates Antithrombin through the Binding to Its Heparin Binding Site 
    Bohdan, Nataliya; Espín, Salvador; Águila, Sonia; Teruel-Montoya, Raúl; Vicente, Vicente; Corral, Javier; Martínez-Martínez, Irene (2016-06-20)
    Heparanase is an endoglycosidase that participates in morphogenesis, tissue repair, heparan sulphates turnover and immune response processes. It is over-expressed in tumor cells favoring the metastasis as it penetrates the ...
  • Modifiable causes of premature death in middle-age in Western Europe: results from the EPIC cohort study 
    Muller, David-C; Johansson, Mattias; Ferrari, Pietro; Brennan, Paul; Murphy, Neil; Norat, Teresa; Gunter, Marc; Riboli, Elio; Tsilidis, Konstantinos-K; Boutron-Ruault, Marie-Christine; Clavel, Francoise; Dartois, Laureen; Li, Kuanrong; Kaaks, Rudolf; Weikert, Cornelia; Bergmann, Manuela; Boeing, Heiner; Tjonneland, Anne; Overvad, Kim; Luisa-Redondo, M; Agudo, Antonio; Molina-Portillo, Elena; Altzibar, Jone-M; Cirera-Suárez, Lluís; Ardanaz, Eva; Khaw, Kay-Tee; Wareham, Nicholas-J; Key, Timothy-J; Travis, Ruth-C; Bamia, Christina; Orfanos, Philippos; Trichopoulou, Antonia; Palli, Domenico; Pala, Valeria; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Bueno-de-Mesquita, H-Bas; Verschuren, W-M-Monique; Struijk, Ellen-A; Peeters, Petra-H; Engstrom, Gunnar; Melander, Olle; Sund, Malin; Weiderpass, Elisabete; Skeie, Guri; Lund, Eiliv (2016-12)
    BACKGROUND: Life expectancy is increasing in Europe, yet a substantial proportion of adults still die prematurely before the age of 70 years. We sought to estimate the joint and relative contributions of tobacco smoking, ...
  • Comparison of abdominal adiposity and overall obesity in relation to risk of small intestinal cancer in a European Prospective Cohort 
    Lu, Yunxia; Cross, Amanda-J; Murphy, Neil; Gunter, Marc-J; Riboli, Elio; Freisling, Heinz; Ferrari, Pietro; Travis, Ruth-C; Katzke, Verena-A; Kaaks, Rudolf; Olsson, Asa; Johansson, Ingegerd; Renstrom, Frida; Panico, Salvatore; Pala, Valeria; Palli, Domenico; Tumino, Rosario; Peeters, Petra-H; Siersema, Peter-D; Bueno-de-Mesquita, H-B; Klinaki, Eleni; Tsironis, Christos; Trichopoulou, Antonia; Agudo, Antonio; Navarro, Carmen; Sánchez, María-José; Barricarte, Aurelio; Boutron-Ruault, Marie-Christine; Fagherazzi, Guy; Racine, Antoine; Weiderpass, Elisabete (2016-07)
    BACKGROUND: The etiology of small intestinal cancer (SIC) is largely unknown, and there are very few epidemiological studies published to date. No studies have investigated abdominal adiposity in relation to SIC. METHODS: ...
  • miRNA-197 and miRNA-223 and cardiovascular death in coronary artery disease patients 
    Orenes-Piñero, Esteban; Marín, Francisco; Lip, Gregory-Y-H (2016-05)
  • Antithrombin controls tumor migration, invasion and angiogenesis by inhibition of enteropeptidase 
    Luengo-Gil, Ginés; Águila, Sonia; Bohdan, Nataliya; Antón, Ana-Isabel; Espín, Salvador; Ayala-de-la-Peña, Francisco; Vicente, Vicente; Corral, Javier; Martínez-Martínez, Irene; Inmaculada-Calvo, María; Martin-Villar, Ester; Quintanilla, Miguel (2016-06-08)
    Antithrombin is a key inhibitor of the coagulation cascade, but it may also function as an anti-inflammatory, anti-angiogenic, anti-viral and anti-apoptotic protein. Here, we report a novel function of antithrombin as a ...
  • Caffeine administration prevents retinal neuroinflammation and loss of retinal ganglion cells in an animal model of glaucoma 
    Madeira, María-H; Ortín-Martínez, Arturo; Nadal-Nicolás, Francisco-M; Vidal-Sanz, Manuel; Agudo-Barriuso, Marta; Ambrosio, Antonio-F; Santiago, Ana-Raquel (2016-06-08)
    Glaucoma is the second leading cause of blindness worldwide, being characterized by progressive optic nerve damage and loss of retinal ganglion cells (RGCs), accompanied by increased inflammatory response involving retinal ...
  • Validity of anthropometric measurements and weight perceptions reported by relatives of children under 4 years old 
    Patiño-Villena, Begoña; González, Eduardo; Chirlaque-López, María-Dolores; Salmerón-Martínez, Diego; Navarro, Carmen (2016-07)
    OBJECTIVE: To assess the validity of weight and height measurements reported by parents and the perception of their children's weight status in order to assess the prevalence of overweight children under 4 years old. ...
  • The Orthology Ontology: development and applications 
    Fernández-Breis, Jesualdo-Tomás; Legaz-García, María-del-Carmen; Chiba, Hirokazu; Uchiyama, Ikuo (2016-12)
    BACKGROUND: Computational comparative analysis of multiple genomes provides valuable opportunities to biomedical research. In particular, orthology analysis can play a central role in comparative genomics; it guides ...
  • Generation of open biomedical datasets through ontology-driven transformation and integration processes 
    Legaz-García, María-del-Carmen; Menárguez-Tortosa, Marcos; Fernández-Breis, Jesualdo-Tomás; Minarro-Giménez, José-Antonio (2016-12)
    BACKGROUND: Biomedical research usually requires combining large volumes of data from multiple heterogeneous sources, which makes difficult the integrated exploitation of such data. The Semantic Web paradigm offers a natural ...
  • Autologous bone marrow mononuclear cells as neuroprotective treatment of amyotrophic lateral sclerosis 
    Ruiz-López, Francisco-José; Blanquer-Blanquer, Miguel (2016)
  • Melanopsin-Containing or Non-Melanopsin-Containing Retinal Ganglion Cells Response to Acute Ocular Hypertension With or Without Brain-Derived Neurotrophic Factor Neuroprotection 
    Nadal-Nicolás, Francisco-M; Bernal-Garro, José-M; Villegas-Pérez, María-Paz; Agudo-Barriuso, Marta; Vidal-Sanz, Manuel; Rovere, Giuseppe; Wang, Jiawei; García-Carrillo, Nuria (2016-12-08)
    PURPOSE: To analyze the responses of different retinal ganglion cell (RGC) types to acute ocular hypertension (AOH) and intravitreal administration of brain-derived neurotrophic factor (BDNF). METHODS: In adult albino rats, ...
  • Involvement of P2X7 receptor in neuronal degeneration triggered by traumatic injury 
    Nadal-Nicolás, Francisco-M; Galindo-Romero, Caridad; Valiente-Soriano, Francisco-Javier; Salinas-Navarro, Manuel; Agudo-Barriuso, Marta; Barberá-Cremades, María; de-Torre-Minguela, Carlos; Pelegrín, Pablo (2016-12-08)
    Axonal injury is a common feature of central nervous system insults that culminates with the death of the affected neurons, and an irreversible loss of function. Inflammation is an important component of the neurodegenerative ...
  • Endothelin B Receptors on Primary Chicken Muller Cells and the Human MIO-M1 Muller Cell Line Activate ERK Signaling via Transactivation of Epidermal Growth Factor Receptors 
    Harun-Or-Rashid, Mohammad; Konjusha, Dardan; Hallbook, Finn; Galindo-Romero, Caridad (2016-12-08)
    Injury to the eye or retina triggers Müller cells, the major glia cell of the retina, to dedifferentiate and proliferate. In some species they attain retinal progenitor properties and have the capacity to generate new ...
  • Topical Treatment With Bromfenac Reduces Retinal Gliosis and Inflammation After Optic Nerve Crush 
    Nadal-Nicolás, Francisco-M; Sobrado-Calvo, Paloma; Villegas-Pérez, María-Paz; Rovere, Giuseppe; García-Bernal, David; Vidal-Sanz, Manuel; Agudo-Barriuso, Marta (2016-11-10)
    PURPOSE: To study the effect of topical administration of bromfenac, a nonsteroidal anti-inflammatory drug (NSAID), on retinal gliosis and levels of prostaglandin E2 (PGE2) after complete optic nerve crush (ONC). METHODS: ...
  • SEOM clinical guidelines for the management of germ cell testicular cancer (2016) 
    Aparicio, J; Terrasa, J; Duran, I; Germa-Lluch, J-R; García-del-Muro, X; Girones, R; González-Billalabeitia, Enrique; Guma, J; Maroto, P; Pinto, A (2016-12)
    Testicular cancer represents the most common malignancy in males aged 15-34 years and is considered a model of curable neoplasm. Maintaining success, reducing treatment burden, and focusing on survivorship are then key ...
  • Tomato Juice Consumption Modifies the Urinary Peptide Profile in Sprague-Dawley Rats with Induced Hepatic Steatosis 
    Martín-Pozuelo, Gala; González-Barrio, Rocío; García-Alonso, Javier; Periago-Castón, María-Jesús; Barberá, Gonzalo-G; Albalat, Amaya; Mullen, William; Mischak, Harald (2016-10-26)
    Non-alcoholic fatty liver disease (NAFLD) is the most common liver disorder in Western countries, with a high prevalence, and has been shown to increase the risk of type 2 diabetes, cardiovascular disease (CVD), etc. Tomato ...
  • Menstrual and Reproductive Factors and Risk of Gastric and Colorectal Cancer in Spain 
    Fernández-de-Larrea, Nerea; Lope, Virginia; Perez-Gomez, Beatriz; Sierra, Angeles; Pollan, Marina; Aragones, Nuria; Martin, Vicente; Moreno, Victor; Costas, Laura; Longo, Federico; Juan-Jiménez-Moleon, José; Llorca, Javier; Ascunce, Nieves; Peiro-Perez, Rosana; Altzibar, Jone-M; Tardon, Adonina; Alguacil, Juan; Navarro, Carmen; Belen-Vega, Ana; Villafane, Amaya; Castano-Vinyals, Gemma; Kogevinas, Manolis (2016-10-24)
    BACKGROUND: Sex hormones play a role in gastric cancer and colorectal cancer etiology, however, epidemiological evidence is inconsistent. This study examines the influence of menstrual and reproductive factors over the ...

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