Repositorio Dspace

Envíos recientes

02.06. Área de Salud VI Vega Media: Envíos recientes

  • Implication of Hepsin from Primary Tumor in the Prognosis of Colorectal Cancer Patients 
    Zaragoza-Huesca, David; Nieto-Olivares, Andres; Garcia-Molina, Francisco; Ricote, Guillermo; Montenegro, Sofia; Sánchez-Canovas, Manuel; Garrido-Rodríguez, Pedro; Penas-Martínez, Julia; Vicente, Vicente; Martínez, Francisco; Lozano, Maria-Luisa; Carmona-B (MDPI, 10.3390can)
    Hepsin is a type II transmembrane serine protease whose deregulation promotes tumor invasion by proteolysis of the pericellular components. In colorectal cancer, the implication of hepsin is unknown. Consequently, we aimed ...
  • Comprehensive Landscape of Diagnostic, Prognostic and Predictive Biomarkers in Colorectal Cancer: From Genomics to Multi-Omics Integration in Precision Medicine. 
    Agüera-Sánchez, Alfonso; Peña-Ros, Emilio; Martínez-Martínez, Irene; García-Molina, Francisco (MDPI, 2026-01-12)
    Colorectal cancer (CRC) remains one of the leading causes of cancer-related morbidity and mortality worldwide. Despite advances in screening and therapeutic strategies, early detection and individualized treatment remain ...
  • Impact of the COVID-19 Pandemic on the Outcomes of a Multifaceted Program on Antibiotic Prescribing in Primary Care Among Children Under Three Years of Age 
    Martín-Ayala, Gema; Alfayate-Miguélez, Santiago; Jiménez-Guillén, Casimiro; AlcarazQuiñonero, Manuel; Iofrio-de-Arce, Antonio; Arnau-Sánchez, José (MDPI, 2026-01-19)
    Background/objective: Inappropriate antibiotic use in paediatric populations is a leading driver of antimicrobial resistance. In the Murcia Region, Spain, the Purapi program promotes the rational use of antibiotics among ...
  • De novomutations in antithrombin deficiency: high frequency and heterogeneous mechanisms. 
    Garrido-Rodríguez, Pedro; de-la-Morena-Barrio, Belén; Bravo-Pérez, Carlos; Cifuentes-Riquelme, Rosa; Padilla, José; Navarro, Esther; Llamas-López, María; Minano, Antonia; Teruel-Montoya, Raúl; Rodríguez-Alen, Agustín; Velasco, Francisco; Blanco, María-J; López-Fernández, María-F; Fernández-Pérez, Beatriz; Asenjo, Susana; González-Porras, José-R; Vicente, Vicente; Lozano-Almela, María-Luisa; de-la-Morena-Barrio, María-Eugenia; Corral, Javier (2026-01-29)
    Not available.
  • Subclinical atherosclerosis in rheumatoid arthritis is driven by MicroRNA polymorphisms and NETosis. 
    Reguilón-Gallego, Laura; Gómez-Gómez, Jesús-Humberto; Carrillo-Tornel, Salvador; Saiz-Cuenca, Encarnación; Pina, María-F; Guzmán-Almansa, Miriam; García-Barbera, Nuria; Guijarro-Carrillo, Pedro-J; Hervés, Ignacio; Plasencia-Martínez, Juana-María; Herranz, María-T; Lozano, María-Luisa; Pérez-Sánchez, Carlos; López-Pedrera, Chary; Martínez, Constantino; González-Conejero, Rocío (SPRINGERNATURE, 2026-02-09)
  • In-hospital testing of NIVPredict - an AI tool for early prediction of non-invasive ventilation outcome in acute respiratory failure 
    Yu, Hang; Saffaran, Sina; Ali, Abdisamad; Henry, Catherine; Mustfa, Naveed; Thomas, Ajit; Rajhan, Ashwin; Isrhad, Sannaan; Weaver, Liam; Tonelli, Roberto; Menga, Luca-S; Zhang, Qingchen; Samadi, Moein-Einollahzadeh; Schuppert, Andreas; Laffey, John-G; Camporota, Luigi; Esquinas-Rodríguez, Antonio; Grieco, Domenico-L; Antonelli, Massimo; Martins-de-Lima, Lucas; Kawano-Dourado, Letícia; Maia, Israel-S; Cavalcanti, Alexandre-Biasi; Clini, Enrico; Scott, Timothy-E; Bates, Declan-G (SPRINGERNATURE, 2026-02-15)
  • Allogeneic HCT as Consolidation in B-cell Lymphomas After Exposure to Bispecific Antibodies: A GETH-TC Study. 
    Peña, Marta; Losi, Giulia; Navarro, Víctor; Qualls, David-A; Crombie, Jennifer-L; Mariotti, Jacopo; Bramanti, Stefania; Fabbri, Nicole; Serna, Ángel; Serroukh, Yasmina-Im; Balaguer-Rosello, Aitana; van-der-Poel, Marjolein-Wm; Hsu, Ya-Ting; Jiménez-Ubieto, Ana; McKinnely, Christopher; López-Corral, Lucía; Panizo, Carlos; Pérez-Simón, José-Antonio; Rovira, Montserrat; Saldana, Raquel; Kwon, Mi; Solano, Carlos; Valcarcel, David; Pascual-Cascon, María-Jesús; Noriega, Víctor; Sanz, Jaime; Sánchez-Salinas, Andrés; Jurado, Manuel; Calbacho, María; Bento, Leyre; Albo-López, Carmen; Perera, María; Heras-Fernando, Inmaculada; Guerreiro, Manuel; Balsalobre, Pascual; Armand, Philippe; Sureda, Anna; Mussetti, Alberto (2026-01-13)
    Bispecific antibodies (BsAb) targeting CD20 and CD3 have shown efficacy for relapsed/refractory (R/R) B-cell non-Hodgkin lymphoma (B-NHL), but their impact on outcomes following allogeneic hematopoietic cell transplantation ...
  • Neurologists' decision-making in the management of generalised myasthenia gravis: Therapeutic inertia and treatment choices 
    Gutiérrez-Gutiérrez, Gerardo; Gómez-Ballesteros, Rocío; Ares, Adrián; Villaverde-González, Ramón; Reyes, Virginia; Armangue, Thais; Díaz-Abos, Paola; Rebollo, Pablo; Canal, Neus; Querol, Luis; Maurino, Jorge; Cortes-Vicente, Elena (SAGE PUBLICATIONS INC, 2026-02-04)
    The evolving landscape of generalised myasthenia gravis (gMG) treatment with new targeted immunotherapy options presents challenges for neurologists and potentially leads to therapeutic inertia (TI), the failure to initiate ...
  • TKI-mediated inhibition of NLRP1 inflammasome restores erythropoiesis in DBA syndrome 
    Lozano-Gil, Juan-Manuel; Rodríguez-Ruiz, Lola; Palacios, Manuel; Peral, Jorge; Navarro, Susana; Fuster-Soler, José-Luis; Beléndez, Cristina; Jérez-Cayuela, Andrés; Murillo-Sanjuan, Laura; Díaz-de-Heredia, Cristina; López-de-Hontanar, Guzmán; Zubicaray, Josune; Sevilla, Julián; Ferrer-Marín, Francisca; Sepulcre-Cortés, María-Pilar; Cayuela-Fuentes, María-Luisa; García-Moreno, Diana; Martínez-López, Alicia; Tyrkalska, Sylwia-D; Mulero, Victoriano (SPRINGERNATURE, 2026-01-09)
    Diamond-Blackfan anemia syndrome (DBAS) is marked by defective erythropoiesis caused by impaired ribosome biogenesis and aberrant signaling. Here, we investigate how ribosomal stress-induced activation of the NLRP1 ...
  • Expanding the genetic landscape of inherited metabolic diseases using long-read sequencing and transcriptomic profiling 
    Soriano-Sexto, Alejandro; Sánchez-Lijarcio, Obdulia; Beccari, Leonardo; Castejón-Fernández, Natalia; Leal, Fátima; Alcaide, Patricia; de-la-Morena-Barrio, Belén; Bahillo-Curieses, María-del-Pilar; Correcher, Patricia; Hencke-Tresbach, Rafael; López, Laura; Martín-Hernández, Elena; Yahyaoui, Raquel; Ugarte, Magdalena; Rodríguez-Pombo, Pilar; Pérez, Belén (SPRINGERNATURE, 2026-01-26)
    Although next-generation sequencing has emerged as a powerful tool for diagnosing rare diseases (RD), many cases of inherited metabolic diseases (IMD) remain unsolved, hindering the diagnosis, clinical and therapeutic ...
  • Contrast-enhanced CT in sepsis: insights from a European Emergency Radiology survey 
    Stahl, Ann-Christine; Rubarth, Kerstin; Opper-Hernando, María-Isabel; Frisch, Anne; Blanco-Barrio, Ana; Basilico, Raffaella; Miele, Vittorio; Iacobellis, Francesca; Bolanaki, Myrto; Witham, Denis; Dewey, Marc; Pohlan, Julián (SPRINGERNATURE, 2026-01-26)
    Objectives To gain insight into emergency radiologists' views on the role of contrast-enhanced CT (CECT) in sepsis management. Materials and methods This analysis of a survey distributed in 2023 to members of the European ...
  • One-year consolidation with Ponatinib 15 mg in chronic myeloid leukaemia on deep molecular response with Imatinib 
    Pérez-Lamas, Lucía; Manzanares, Mario; Hernández-Boluda, Juan-Carlos; Casado-Montero, Luis-Felipe; Gómez-Casares, María-Teresa; Ayala, Rosa; Xicoy, Blanca; Ferrer-Marín, Francisca; Orti, Guillermo; De-Paz-Arias, Raquel; Osorio-Prendes, Santiago; Pérez-López, Raúl; Mora, Elvira; Ruiz-Nuno, Concepción; Jiménez-Velasco, Antonio; Boque, Concepción; Sierra-Pacho, Magdalena; Martínez-López, Joaquín; Carreño-Tarragona, Gonzalo; Coiras, Mayte; García-Gutiérrez, Valentín (SPRINGERNATURE, 2026-01-20)
    Tyrosine kinase inhibitors (TKIs) discontinuation is the standard option for patients with chronic myeloid leukaemia (CML) in deep molecular response (MR) with imatinib. This study aimed to evaluate the efficacy and safety ...
  • Vaccination and immunization schedule of the Pediatric Spanish Association: 2026 recommendations. 
    Álvarez-García, Francisco-José; Iofrío-de-Arce, Antonio; Álvarez-Aldean, Javier; Garrote-Llanos, Elisa; López-Granados, Lucía; Navarro-Gómez, María-Luisa; Pineda-Solas, Valentín; Rivero-Calle, Irene; Ruiz-Contreras, Jesús; Salamanca-de-la-Cueva, Ignacio; Serrano-Marchuet, Pepe (ELSEVIER, 2026-01)
    The 2026 Vaccination and Immunization Schedule recommended by the Spanish Association of Pediatrics (AEP) for children, adolescents and pregnant women residing in Spain includes the following new features: introduction of ...
  • Is mortality truly higher for oncology patients admitted to intensive care units? A matched cohort observational study 
    Zafra-Poves, Marta; Vicente-Conesa, María-Ángeles; Guirao-García, María-Esperanza; Sánchez-Cánovas, Manuel; Alonso-Fernández, Nuria; Ayala-de-La-Peña, Francisco; Carrillo-Alcaraz, Andrés (SPRINGERNATURE, 2026-02-02)
    Background Cancer patients often develop life-threatening events that prompt intensive care unit (ICU) admission. However, uncertainty regarding prognosis may hinder timely referral. We compared ICU survival in adults with ...
  • Diagnosis and treatment of cutaneous adverse effects of targeted therapy, antibody-drug conjugates, and immunotherapy in cancer patients: a national consensus statement by the Spanish Society of Medical Oncology and the Spanish Academy of Dermatology and Venereology 
    Majem, Margarita; Molina-Mata, Kevin; Mayor-Ibarguren, Ander; Zafra-Poves, Marta; Requena, Celia; Aparisi-Aparisi, Francisco-de-Asis; Carrera, Cristina; Blasco-Cordellat, Ana; Freites-Martínez, Azael; Sanmartín, Onofre (SPRINGERNATURE, 2026-01-28)
    Cancer remains a leading cause of mortality in developed countries, with advancements in targeted therapies, antibody-drug conjugates (ADCs), and immunotherapy significantly improving patient survival. However, these ...
  • Translational and real-world evidence of trastuzumab biosimilar CT-P6 plus pertuzumab in neoadjuvant HER2-positive early breast cancer 
    Alonso-Romero, José-Luis; Martínez-García, Jerónimo; Carrillo-Vicente, Raúl; Fernández-Aramburo, Antonio; Ferrando-Díez, Ángelica; Sánchez-Henarejos, Pilar; De-La-Morena-Barrio, Pilar; Puertes-Boix, Ana; Jiménez, M-Dolores; Peña-Siles, Joaquín; Parejo-Maestre, José-Antonio; De-Las-Heras-Rubio, Antonio; Ruiz-Carreño, Paula (SPRINGERNATURE, 2026-01)
    BackgroundData on neoadjuvant treatment with trastuzumab biosimilars, particularly CT-P6, in combination with pertuzumab, are limited. This study evaluates the efficacy, tolerability, and immunogenicity of CT-P6 plus ...
  • Identification of two epitypes of IGHV unmutated chronic lymphocytic leukemia with distinct B-cell-related epigenetic imprinting and genetic alterations 
    Charalampopoulou, Stella; Ramos-Campoy, Silvia; Durán-Ferrer, Martí; Puiggros, Anna; Kamaso, Joanna; Nguyen-khac, Florence; Rigolin, Gian-Matteo; Cuneo, Antonio; Collado, Rosa; García-Serra, Rocio; Haferlach, Claudia; Ortega, Margarita; Abrisqueta, Pau; Bosch, Francesc; Zenz, Thorsten; Blanco, María-Laura; Salgado, Rocio; García-Malo, María-Dolores; Gimeno, Eva; López-Guillermo, Armando; Campo, Elias; Etter, Laurence; Schoumans, Jacqueline; Espinet, Blanca; Martín-subero, José-I (WILEY, 2026-01)
  • Intensive Chemotherapy With or Without Midostaurin in Adults ?60Years Old With FLT3-Mutated AML: A FILO-DATAML-PETHEMA Real-World Study. 
    Aspas-Requena, Gaspar; Montesinos, Pau; Berard, Emilie; Bertoli, Sarah; Rodríguez-Veiga, Rebeca; Simand, Celestine; Torres, Laura; Peterlin, Pierre; Tormo, Mar; Birsen, Rudy; Bergua-Burgues, Juan-Miguel; Tavernier, Emmanuelle; Bernal-del-Castillo, Teresa; Carre, Martín; Gil, Cristina; Contejean, Adrien; Rodríguez-Arboli, Eduardo; Orvain, Corentin; Rodríguez-Medina, Carlos; Veronese, Lauren; Sayas-Lloris, María-José; Delabesse, Eric; Serrano, Joséfina; Mineur, Ariane; García-Fortes, María; Guieze, Romain; Amigo, María-Luz; Pigneux, Arnaud; Algarra-Algarra, Lorenzo; Recher, Christian; Dumas, Pierre-Yves; Martínez-Cuadron, David (WILEY, 2026-02-11)
    The addition of midostaurin (MIDO) to intensive chemotherapy (IC) improves survival in younger adults with FLT3-mutated acute myeloid leukemia (AML); however, real-world data in elderly patients (?60years) are limited. ...
  • Prediction of oncogene mutation status in non-small cell lung cancer: a systematic review and meta-analysis with a special focus on artificial intelligence-based methods 
    Fuster-Matanzo, Almudena; Picó-Peris, Alfonso; Bellvís-Bataller, Fuensanta; Jimenez-Pastor, Ana; Weiss, Glen J; Martí-Bonmatí, Luis; Lázaro-Sánchez, Antonio-David; Bazaga, David; Banna, Giuseppe L; Addeo, Alfredo; Camps, Carlos; Seijo, Luis M; Alberich-Bayarri, Ángel (SPRINGER NATURE, 2025-09-08)
    OBJECTIVES: In non-small cell lung cancer (NSCLC), non-invasive alternatives to biopsy-dependent driver mutation analysis are needed. We reviewed the effectiveness of radiomics alone or with clinical data and assessed the ...
  • Discordant Patch Test Reactions to 2-Bromo-2-Nitro-Propane-1,3-Diol (Bronopol): A Multicenter Study From REIDAC 
    Sanz-Sánchez, Tatiana; Giménez-Arnau, Ana María; Zaragoza-Ninet, Violeta; Córdoba-Guijarro, Susana; Miquel-Miquel, Francisco Javier; Silvestre-Salvador, Juan-Francisco; González-Pérez, Ricardo; Ruiz-González, Inmaculada; Mercader-García, Pedro; Serra-Baldrich, Esther; Carrascosa-rrillo, José-Manuel; Tous-Romero, Fátima; Ortiz-de Frutos, Francisco-Javier; Rodríguez-Serna, Mercedes; Gatica-Ortega, María-Elena; Paredes-Suárez, Carmen; Navarro-Triviño, Francisco; Chicharro, Pablo; Pastor-Nieto, María-Antonia; Gómez de la Fuente, Enrique; Sánchez-Gilo, Araceli; Andreu-Barasoain, Marta; Pereyra Rodríguez, José Juan; Melé-i-Ninot, Gemma; Sánchez-Pedreño-Guillén, Paloma; Elosua-González, Marta; Grau-Pérez, Mercè; Descalzo, Miguel Ángel; Borrego, Leopoldo (JOHN WILEY AND SONS, 2026-04)

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