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Envíos recientes

03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla): Envíos recientes

  • HLA-A*03 may confer protection against long COVID through an enhanced immune response 
    Pons-Fuster, Eduardo; Martínez-Rodríguez, Rodrigo; Gimeno-Arias, Lourdes; Alcaraz, M-J; Moreno, Marta; Gómez, José-M; Peláez-Ballesta, Ana-Isabel; García, Elisa; Tomas, Cristina; Muñoz, Ángeles; V; Ruiz-Lorente, Inmaculada; Ceballos, Diana; Minguela-Puras, Alfredo; Bernal-Morell, Enrique (ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2025-06)
    BACKGROUND: The COVID-19 pandemic has led to widespread infection, with a significant subset of patients developing persistent symptoms known as Long COVID. Understanding the genetic factors influencing Long COVID ...
  • The action of 7,8-dihydroxyflavone preserves retinal ganglion cell survival and visual function via the TrkB pathway in NMDA-induced retinal excitotoxicity. 
    Gallego-Ortega, Alejandro; Galindo-Romero, Caridad; Vidal-Villegas, Beatriz; Bernal-Garro, José-Manuel; de-la-Villa, Pedro; Avilés-Trigueros, Marcelino; Vidal-Sanz, Manuel (ELSEVIER, 2025-04)
    PURPOSE: To analyze the response of different retinal ganglion cell (RGC) populations to NMDA-induced retinal excitotoxicity and the effect of an intraperitoneal treatment with 7,8-Dihydroxyflavone (DHF), a potent selective ...
  • Step-by-step combination of 99mTc and ICG with endoscopic near infrared cameras in SLN mapping early-stage vulvar cancer 
    Guijarro-Campillo, Alberto-Rafael; Padilla-Iserte, Pablo; Lago, Victor; Quintana-Berto, Raquel; Arnaez-de-la-Cruz, Marta; Nieto-Díaz, Anibal; Del-Pozo, Santiago-Domingo (ELSEVIER SCIENCE INC, 2025-02)
    Vulvar cancer guidelines recommend inguinal sentinel lymph node (SLN) biopsy as the standard of care for patients with unifocal squamous cell carcinoma tumors less than 4 cm and clinically non-suspicious nodes in the groin ...
  • Profile and Usefulness of Serum Cytokines to Predict Prognosis in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease 
    Villacieros-Álvarez, Javier; Espejo, Carmen; Arrambide, Georgina; Dinoto, Alessandro; Mulero, Patricia; Rubio-Flores, Laura; Nieto, Pablo; Alcalá, Carmen; Meca-Lallana, José-Eustasio; Millán-Pascual, Jorge; Martínez-García, Pedro; Bernard-Valnet, Raphael; González-Suarez, Inés; Orviz, Aida; Tellez, Raquel; Navarro-Canto, Laura; Presas-Rodríguez, Silvia; Martínez-Yelamos, Sergio; Cuello, Juan-Pablo; Alonso, Ana; Pinar-Morales, Raquel; Álvarez-Bravo, Gary; Benyahya, Lakhdar; Trouillet-Assant, Sophie; Dyon-Tafan, Virginie; Froment-Tilikete, Caroline; Ruet, Aurelie; Bourre, Bertrand; Deschamps, Romain; Papeix, Caroline; Maillart, Elisabeth; Kerschen, Philippe; Ayrignac, Xavier; Rovira, Alex; Auger, Cristina; Audoin, Bertrand; Montalban, Xavier; Tintore, Mar; Mariotto, Sara; Cobo-Calvo, Álvaro; Marignier, Romain (LIPPINCOTT WILLIAMS & WILKINS, 2025-03)
    OBJECTIVES: To characterize the serum cytokine profile in myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) at onset and during follow-up and assess their utility for predicting relapses and disability. ...
  • Novel insights into antithrombin deficiency enabled by mass spectrometry-based precision diagnostics 
    Kruijt, Mirjam; de-la-Morena-Barrio, María-Eugenia; Corral, Javier; Cobbaert, Christa-M; Ruhaak, L-Renee (ELSEVIER SCIENCE INC, 2025-01)
    BACKGROUND: Although P5 (preventive, personalized, predictive, participatory, psychocognitive) medicine and patient-focused healthcare are gaining ground in various healthcare areas, the diagnosis of antithrombin deficiency ...
  • Oviductin sets the species-specificity of the mammalian zona pellucida 
    de-la-Fuente, Daniel; Maroto, María; Cajas, Yulia-N; Canon-Beltran, Karina; Fernández-González, Raúl; Muñoz-Maceda, Ana; Sánchez-Puig, Juana-M; Blasco, Rafael; Cots-Rodríguez, Paula; Avilés, Manuel; Rizos, Dimitrios; Gutiérrez-Adan, Alfonso (eLIFE SCIENCES PUBL LTD, 2025-06-09)
    The zona pellucida (ZP) is vital for species-specific fertilization as this barrier mediates sperm-oocyte binding. Here, we determined whether sperm from distant mammalian orders (Carnivora, Primates, and Rodentia) could ...
  • Evaluation of a "Simuloteca" as a self-directed learning environment in clinical simulation and validation ofa a student perception questionnaire 
    Adánez-Martínez, Gracia; Pérez-Cánovas, Carlos; de-Gea-García, José-Higinio; Cantero-Sandoval, Antonia; Reyes-Domínguez, Susana-Beatriz; Febrero, Beatriz (UNIV POLITECNICA VALENCIA, EDITORIAL UPV, 2025-12-31)
  • IMU-Based Assessment of Arm Movement in Breast Cancer Survivors: An Exploratory Study 
    Navarro-Martínez, Carlos; Hernán-Villarejo-García, Diego; Carvajal-Espinosa, Rafael; Cánovas-Ambit, Germán; Becerra-Patino, Boryi-A; Pino-Ortega, José (MDPI, 2025-11-06)
  • The Individual Variations in Sperm Quality of High-Fertility Boars Impact the Offspring Production and Early Physiological Functions 
    Toledo-Guardiola, Santa-María; Luongo, Chiara; Martínez-Pastor, Felipe; Soriano-Úbeda, Cristina; Matas-Parra, Carmen (MDPI, 2025-06-13)
    Artificial insemination (AI) is essential in intensive pig production, which significantly depends on semen quality from boars selected for health, genetics, and fertility. While AI aims to improve productivity, larger ...
  • Patterns of Polydrug Use in Patients Presenting at the Emergency Department with Acute Intoxication 
    Manjon-Prado, Helena; Serrano-Santos, Enrique; Osuna-Carrillo-Albornoz, Eduardo (MDPI, 2025-05-07)
    Studies analyzing the prevalence of associated substance use are limited. Currently, the World Health Organization (WHO) defines polydrug use as the concurrent (simultaneous use) or sequential (use of one drug followed by ...
  • Early Cell Adhesion of Periodontal Ligament Stem Cells on 3D Printed Polylactic Acid/Hydroxyapatite Scaffolds: An In Vitro Study 
    Serrano-Belmonte, Ildefonso; Montero, Javier; Guerrero-González, Elena; Munteanu, Alexandra; Pérez-Fernández, Virginia; Pérez-Silva, Amparo; Martínez-Cánovas, Ascensión (MDPI, 2025-11-20)
    Polylactic acid (PLA) and its composites with hydroxyapatite (HA) have been studied in the field of bone repair applications. The objective of this study was to evaluate the biocompatibility of PLA/HA at different ...
  • Stability Studies of Clonazepam 2.5 mg/mL Oral Solution and 1 mg/mL Parenteral Solution in Pre-Filled Polypropylene Syringes 
    Ruiz-Ramírez, Juan-Carlos; Talsi-Hamdani, Icram; Bermúdez-Gazquez, Laura; Viney, Alice-Charlotte; Alonso-Herreros, José-M (MDPI, 2025-10-07)
    Background: Clonazepam is a benzodiazepine drug indicated in all clinical forms of epileptic seizures, various forms of myoclonic seizures, myoclonus and other abnormal movements. At present, it is classified as a hazardous ...
  • Propranolol Administration During Morphine Addiction Attenuates Reinstatement of Drug-Aversive Memories Caused by Exposure to Stressful Stimuli 
    Cánovas-Cabanes, Alberto; Teruel-Fernández, Francisco-Javier; Fernández-López, Lucía; Martínez-Laorden, Elena; Navarro-Zaragoza, Javier; Almela-Rojo, Pilar (MDPI, 2025-12-23)
    Background/Objectives: Situations previously paired with drug use can become conditioned stimuli (i.e., physical stress or psychosocial stress) that elicit intense craving and relapse, even after prolonged abstinence. ...
  • Synergizing Virtual Screening and Zebrafish Models to Identify Resveratrol-Derived Antiaging Polyphenols 
    Hernández-Silva, David; Cabello-Villalba, Cynthia; Cayuela-Fuentes, María-Luisa; Pérez-Sánchez, Horacio; Alcaraz-Pérez, Francisca (MDPI, 2025-10-28)
    Background: Telomere shortening and chronic inflammation are well-established hallmarks of aging and age-related diseases, often resulting in impaired cellular function. Identifying compounds with anti-aging potential is ...
  • Association Between Dietary Intake and Blood Concentrations of One-Carbon-Metabolism-Related Nutrients in European Prospective Investigation into Cancer and Nutrition 
    Park, Jin-Young; Van-Puyvelde, Heleen; Regazzetti, Lea; Clasen, Joanna-L; Heath, Alicia-K; Eussen, Simone; Ueland, Per-Magne; Johansson, Mattias; Biessy, Carine; Zamora-Ros, Raúl; Huerta-Castaño, José-María; Sánchez, María-José; Ocke, Marga; Schulze, Matthias-B; Schiborn, Catarina; Braaten, Tonje-Bjorndal; Skeie, Guri; Sacerdote, Carlotta; Castilla, Jesús; Karlsson, Therese; Johansson, Ingegerd; Kyro, Cecilie; Tjonneland, Anne; Tong, Tammy-Y-N; Katzke, Verena; Bajracharya, Rashmita; Lasheras, Cristina; Midttun, Oivind; Vollset, Stein-Emil; Vineis, Paolo; Masala, Giovanna; Amiano, Pilar; Tumino, Rosario; Baldassari, Iván; Weiderpass, Elisabete; Riboli, Elio; Gunter, Marc-J; Freisling, Heinz; Rinaldi, Sabina; Muller, David-C; Huybrechts, Inge; Ferrari, Pietro (MDPI, 2025-06-10)
    Background/Objectives: We examined the association between dietary intake and blood concentrations of one-carbon metabolism (OCM)-related nutrients in the European Prospective Investigation into Cancer and Nutrition (EPIC). ...
  • Impact of Chronic Nitrate and Citrulline Malate Supplementation on Performance and Recovery in Spanish Professional Female Soccer Players: A Randomized Controlled Trial 
    Ramírez-Munera, Marta; Arcusa, Raúl; López-Román, Francisco-Javier; Ávila-Gandía, Vicente; Pérez-Pinero, Silvia; Muñoz-Carrillo, Juan-Carlos; Luque-Rubia, Antonio-Jesús; Marhuenda, Javier (MDPI, 2025-07-21)
    Background: Pre-season training is critical for developing tolerance to high physical demands in professional soccer, and nitric oxide (NO) precursors such as dietary nitrate (NO(3)(-)) and citrulline malate (CM) can support ...
  • Diabetes-Related Dietary Patterns and Endometrial Cancer Risk and Survival in the European Prospective Investigation into Cancer and Nutrition Study 
    Torres-Laiton, Luisa; Luján-Barroso, Leila; Nadal-Zaragoza, Nuria; Castro-Espín, Carlota; Jakszyn, Paula; Panico, Camilla; Le-Cornet, Charlotte; Dahm, Christina-C; Petrova, Dafina; Rodríguez-Palacios, Daniel; Jannasch, Franziska; Masala, Giovanna; Dossus, Laure; Padroni, Lisa; Guevara, Marcela; Schulze, Matthias-B; Fortner, Renee-Turzanski; Tumino, Rosario; Crous-Bou, Marta (MDPI, 2025-05-12)
    BACKGROUND/OBJECTIVES: Endometrial cancer (EC)'s major risk factors include obesity and diabetes, both strongly related with lifestyle choices and dietary factors. Our study aimed to evaluate the relationship between ...
  • Diet, Advanced Maternal Age, and Neonatal Outcomes: Results from the GESTAGE Study 
    Puche-Juarez, María; Toledano, Juan-M; Hinojosa-Nogueira, Daniel; de-Paco-Matallana, Catalina; Sánchez-Romero, Javier; Ochoa, Julio-J; Carrillo, María-Paz; Martín-Álvarez, Estefanía; Díaz-Castro, Javier; Moreno-Fernández, Jorge (MDPI, 2025-01-17)
    Maternal nutrition during pregnancy plays a pivotal role in influencing both maternal and fetal health, impacting neonatal anthropometric outcomes and long-term disease susceptibility. An advanced maternal age (AMA ? 35 ...
  • Graphene-Based Materials for Bone Regeneration in Dentistry: A Systematic Review of In Vitro Applications and Material Comparisons 
    Narváez-Romero, Azahara-María; Rodríguez-Lozano, Francisco-Javier; Pecci-Lloret, María-Pilar (MDPI, 2025-01-08)
    INTRODUCTION: Graphene, a two-dimensional arrangement of carbon atoms, has drawn significant interest in medical research due to its unique properties. In the context of bone regeneration, graphene has shown several promising ...
  • Use of Saliva Analytes as a Predictive Model to Detect Diseases in the Pig: A Pilot Study 
    Llamas-Amor, Eva; Ortin-Bustillo, Alba; López-Martínez, María-José; Muñoz-Prieto, Alberto; García-Manzanilla, Edgar; Arense-Gonzalo, Julián; Miralles-Chorro, Aida; Fuentes, Pablo; Martínez-Subiela, Silvia; González-Bulnes, Antonio; Goyena, Elena; Martínez-Martínez, Andrea; Ceron, José-Joaquín; Tecles, Fernando (MDPI, 2025-02-13)
    BACKGROUND/OBJECTIVES: Saliva is gaining importance as a diagnostic sample in pigs. The aim of this research was to evaluate a panel of salivary analytes in three porcine diseases and establish predictive models to detect ...

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