Repositorio Dspace

Envíos recientes

03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla): Envíos recientes

  • Estudio Delphi multidisciplinar sobre riesgo residual en pacientes con enfermedad renal crónica y diabetes mellitus tipo 2 
    Ortiz, Alberto; Cebrián-Cuenca, Ana-María; Soto, Alfonso; Reyes, Andrés; Gorriz, José-Luis (SOCIEDAD ESPAÑOLA DE NEFROLOGIA DR RAFAEL MATESANZ, 2025-08)
    BACKGROUND AND OBJETIVE: Currently, patients with chronic kidney disease (CKD) and type-2 diabetes mellitus (T2DM) present a persistent residual renal and cardiovascular (CV) risk despite receiving standard treatment. ...
  • The diagnostic efficiency of tissue factor pathway inhibitor 2 methylation in the detection of colorectal cancer: a systematic review and meta-analysis 
    Wang, Xiao-Ling; Qin, Shuo; Liu, Li; Jia, Yu-Qi; Wang, Ying; Zhou, Yu-Jie; Ramos-Molina, Bruno; Valladares-Ayerbes, Manuel; Eidens, Moritz; Liu, Zhi-Zhen (AME PUBLISHING COMPANY, 2025-06)
    BACKGROUND: Colorectal cancer (CRC) is a common malignant tumor of the digestive tract. Screening of high risk populations and early diagnosis of CRC are of great importance. Tissue factor pathway inhibitor 2 (TFPI2) ...
  • Transcriptomic Predictors of Survival for Palbociclib plus Endocrine Therapy Versus Capecitabine in Aromatase Inhibitor-Resistant Breast Cancer From the GEICAM/2013-02 PEARL Trial 
    Agrawal, Yash N.; Fernandez-Martinez, Aranzazu; Gil-Gil, Miguel; Zielinski, Christoph; Ruiz-Borrego, Manuel; Ciruelos, Eva Maria; Munoz, Montserrat; Margeli, Mireia; Bermejo, Begona; Anton, Antonio; Kahan, Zsuzsanna; Csoeszi, Tibor; Alonso-Romero, Jose Luis; Garcia-Saenz, Jose angel; Sanchez-Rovira, Pedro; Alvarez, Elena; Chacon, Jose Ignacio; Gonzalez-Santiago, Santiago; Rodriguez, Cesar A.; Servitja, Sonia; Pfefferle, Adam D.; Herranz, Jesus; Liu, Yuan; Carey, Lisa A.; Romero-Camarero, Isabel; Caballero, Rosalia; Guerrero-Zotano, Angel; Perou, Charles M.; Martin, Miguel (LIPPINCOTT WILLIAMS & WILKINS, 2025-07)
    PURPOSE: For hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) metastatic breast cancer (MBC), first-line cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) + endocrine therapy (ET) is ...
  • The COVID-19 vaccination health literacy questionnaire (CVHL-Q): Design and validation according to classic psychometric and Rasch analyses 
    Rodríguez-Blázquez, Carmen; Ayala, Alba; Bas-Sarmiento, Pilar; Fernández-Gutiérrez, Martina; Falcón-Romero, María; Romay-Barja, María; Joa, María (W B SAUNDERS CO LTD, 2025-10)
    OBJECTIVES: This study aimed to describe the COVID-19 vaccination health literacy questionnaire (CVHL-Q) and test its psychometric properties in the Spanish general population using Classic Test Theory (CTT) and Rasch ...
  • BO-112 Plus Pembrolizumab for Patients With Anti-PD-1-Resistant Advanced Melanoma: Phase II Clinical Trial SPOTLIGHT-203 
    Márquez-Rodas, Iván; Dutriaux, Caroline; Saiag, Philippe; de-la-Cruz-Merino, Luis; Castañon-Álvarez, Eduardo; Robert, Caroline; Rodríguez-Moreno, Juan-F; Arance, Ana; Cerezuela-Fuentes, Pablo; Montaudie, Henri; Fernández-de-Sanmamed-Girón, Miguel; González-Cao, María; Charles, Julie; López-Criado, María-Pilar; Berrocal, Alfonso; de-Miguel, Enrique; Funck-Brentano, Elisa; Prey, Sorilla; Álamo-de-la-Gala, María-del-Carmen; Melero, Ignacio; Avilés-Izquierdo, José-Antonio; Roman, Ruth; García-Pelaez, Beatriz; Rodríguez, Sonia; Trnkova, Zuzana-Jirakova; Quintero, Marisol; Macia, Sonia; Chaney, Marya-F; Dalle, Stephane (LIPPINCOTT WILLIAMS & WILKINS, 2025-09)
    PURPOSE: Patients with anti-PD-1-resistant melanoma (MEL) have no well-defined standard of care. BO-112 is a synthetic, double-stranded RNA (poly I:C) nanoplexed with polyethylenimine that when administered intratumorally ...
  • Magnitude of chronic kidney disease in Spain. 
    Santamaria, Rafael; Escobar, Carlos; Aranda, Unai; Palacios, Beatriz; Capel, Margarita; Hernández, Ignacio; Cebrián-Cuenca, Ana-María; Alcazar, Roberto; Gorostidi, Manuel (ELSEVIER, 2025-05)
  • Protein diversity, type 2 diabetes, and effect modifiers: a multi-country prospective study 
    Mozaffari, Hadis; Imamura, Fumiaki; Murphy, Rachel A.; Jessri, Mahsa; Sharp, Stephen J.; Forouhi, Nita G.; Wareham, Nicholas J.; Ibsen, Daniel B.; Dahm, Christina C.; Huerta, Jose Maria; Molina-Montes, Esther; Nickel, Daniela, V; Rolandsson, Olov; Sacerdote, Carlotta; Schulze, Matthias B.; Gonzalez-Martin, Jon Ander; Guevara, Marcela; Nilsson, Peter M.; Panico, Salvatore; Winkvist, Anna; Conklin, Annalijn, I (OXFORD UNIV PRESS, 2025-04-12)
    BACKGROUND: Dietary diversity may affect type 2 diabetes (T2D) but no studies have examined protein diversity by source. We examined five diversity scores and the 10-year risk of T2D and effect modification. METHODS: A ...
  • 10 key issues for prevention, monitoring and non-pharmacological treatment of delirium in critically ill patients 
    Valles-Fructuoso, Olga; Rodríguez-Mondéjar, Juan-José; Alonso-Crespo, David; Robleda-Font, Gemma; López-López, Candelas; Gil-Castillejos, Diana; Acevedo-Nuevo, María (ELSEVIER SCIENCE INC, 2025-04)
    In intensive care units, due to critical illness nature and environment special characteristics, it is relatively common for admitted patients to develop acute confusional syndrome (ACS) or delirium. The nurse's duties are ...
  • Evolving epidemiology of HCC in Spain 
    Sala, Margarita; Pascual, Sonia; Roca, Maria Rosa Rota; Rodriguez, Manuel; Chiminazzo, Valentina; Sala, Margarita; Pascual, Sonia; Roca, Maria Rosa Rota; Matilla, Ana Maria; Campos, Marta; Delgado, Manuel; Ferrerez, Maria Teresa; Montero, Jose Luis; Guerrero, Antonio; Aracil, Carles; Rodriguez-Lopez, Carlos; Sogbe, Miguel; Olmo, Javier Fuentes; Minguez, Beatriz; Vallejo-Senra, Nicolau; Unceta, Paloma Rendon; Clos, Ariadna; Diaz-Bethencourt, Dacil; Sanchez, Araceli Garcia; Castro, Raisa Quinones; Bustamante, Javier; Perello, Christie; Ponce, Juan Jose Urquijo; Serra, Hernan Andreu; Llamoza-Torres, Camilo Julio; Montoliu, Silvia; Fernandez-Marcos, Christina; Guiberteau, Ana; Vergara, Mercedes; Fernandez-Lopez, Alexia Maria; Gutierrez-Garcia, Maria Luisa; Hernaez-Alsina, Tania; Coll, Susana; Cuyas, Berta; Morillas, Maria Julia; Olmedo, Susana Rebolledo; Fernandez-Bermejo, Miguel; Roget, Merce; Ramos, Irina Calvo; Rio, Gemma Pacheco del; Rifa, Raimon; Gacho, Pilar Conde; Barrio, Monica Llorente; Gomez-Rubio, Mariano; Penas, Irene; Cachero, Alba; Reig, Maria; Gonzalez-Santiago, Jesus Manuel; Giraldez, Alvaro; Guerrero, Marta; Segarra, Jose Xavier; Romero-Gutierrez, Marta; Lledo, Jose Luis; Diaz-Gonzalez, Alvaro; Cortes-Garcia, Luis; Delgado, Carolina; Vazquez-Rodriguez, Sergio; Serra, Isabel; Inarrairaegui, Mercedes; Fernandez-Marcos, Cristina; Rodriguez-Gonzalez, Milagros; Barrio, Monica Llorente; Diaz-Bethencourt, Dacil; Lazaro, Maria; Bermudez-Ramos, Maria; Lue, Alberto; Molina, Esther; Macias-Rodriguez, Manuel Alberto; Varela, Maria (ELSEVIER, 2025-05)
    BACKGROUND & AIMS: The epidemiological landscape of hepatocellular carcinoma (HCC) in Europe is evolving. This study aims to provide an updated description of the current epidemiology of liver cancer in Spain. METHODS: ...
  • Evaluation of results from the ARGOS Program: prevention of alcohol, tobacco, and cannabis use in adolescents 
    Díaz-Cutillas, Mario; Espí-Ballester, Irene; Villar-Lorenzo, Ana-Belén; Puerta-Ortuño, Consuelo; López-Davis, Sylvia; Monteagudo-Piqueras, Olga; Medina-Infante, Berta-A (ELSEVIER, 2025)
    OBJECTIVE: To evaluate the impact of the ARGOS Community-Educational Program on reducing alcohol, tobacco, and cannabis use, resisting peer pressure to consume, and on increasing the perception of risk associated with ...
  • Illustrated capsules from the Advanced Course in Platelet Research 
    Buduo, Christian Andrea Di; Abbonante, Vittorio; Malara, Alessandro; Balduini, Alessandra; Waller, Amie K.; Watson, Steve P.; Martin, Eleyna M.; Bridge, Lloyd; Gibbins, Jonathan; Hers, Ingeborg; Masson, Claire; Eckly, Anita; Poulter, Natalie S.; Martinez-Garcia, Beatriz; Aguila, Sonia; Gresele, Paolo; Momi, Stefania; Amstrong, Paul; Rondina, Matthew; Troitino, Sara; Garcia, Angel; Bastida, Jose M.; Quilez, Ana Marin; Fuentes, Ana Sanchez; Rivera, Jose; Torres-Ruiz, Raul; Ojeda-Walczuk, Paula; Morgan, Neil, V; de la Morena, Belen; Ramaekers, Kato; Tran, My; De Wispelaere, Koen; Freson, Kathleen; Bergmeier, Wolfgang; Greinacher, Andreas; He, Fan; Oh, Stephen; Di Paola, Jorge; Semple, John W.; Lozano, Maria L.; Llamas, Pilar; Ward, Chris (ELSEVIER, 2025-02)
    This series of illustrated capsules summarizes the presentations made by the speakers at the first International Advanced Course in Platelet Research held in Murcia (Spain) from 27 to 28 September, 2024. This is the first ...
  • Spanish Registry of Renal Patients: 2022 Report and evolutive analysis 
    Quiroga, Borja; Mahillo, Beatriz; Mazuecos, Auxiliadora; Ortiz, Alberto; Comas-Farnes, Jordi; Hernández-Marrero, Domingo; Trujillo-Alemán, Sara; Santiuste-de-Pablos, Carmen; Rodríguez-Arévalo, Olga-Lucía; Marqués-Vidas, María; Slon-Roblero, M-Fernanda; Artamendi-Larrañaga, Marta; Moina-Eguren, Íñigo; Valentín-Muñoz, María-de-la-Oliva; Rodríguez-Camblor, Marta; Moreno-Alia, Inmaculada; Bouzas-Caamaño, M-Encarnación; Galan, M-Antonia-Blanco; Deira-Lorenzo, Javier; García-López, Héctor; Arribas-Monzon, Federico-Eduardo; Gómez-Marqués, Gonzalo; Rodríguez-Benot, Alberto; Domínguez-Gil, Beatriz; Álvarez, Emilio-Sanchez (SOCIEDAD ESPAÑOLA DE NEFROLOGIA DR RAFAEL MATESANZ, 2025-04)
    INTRODUCTION: Chronic kidney disease (CKD) will be the second leading cause of death in Spain by 2100. The Spanish Renal Disease Registry (REER) records the incidence, prevalence and mortality of all patients requiring ...
  • Hepatic HKDC1 deletion alleviates western diet-induced MASH in mice 
    Xu, Kai; Corona-Avila, Irene; Frutos-Bernal, María-Dolores; Núñez-Sánchez, María-Ángeles; Makhanasa, Dhruvi; Shah, Pratham-Viral; Guzmán, Grace; Ramos-Molina, Bruno; Priyadarshini, Medha; Khan, Md-Wasim (ELSEVIER, 2025-04)
    The global prevalence of Metabolic Dysfunction-Associated Steatohepatitis (MASH) has been rising sharply, closely mirroring the increasing rates of obesity and metabolic syndrome. MASH exhibits a strong sexual dimorphism ...
  • Navigating gene editing in porcine embryos: Methods, challenges, and future perspectives 
    Hamze-Araujo, Julieta-Gabriela; Cambra, Josep-M; Navarro-Serna, Sergio; Martínez-Serrano, Cristina-A (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2025-03)
    Gene editing technologies, particularly CRISPR/Cas9, have emerged as transformative tools in genetic modification, significantly advancing the use of porcine embryos in biomedical and agricultural research. This review ...
  • Timing of exercise differentially impacts adipose tissue gain in male adolescent rats (vol 93, 102100, 2025) 
    Kutsenko, Y.; Iniguez, L. P.; Barreda, A.; Pardo-Marin, L.; Toval, A.; Garrigos, D.; Martinez-Morga, M.; Pujante, S.; Do-Couto, B. Ribeiro; Tseng, K. Y.; Garaulet, M.; Wisniewska; Irimia, M.; Ferran, J. L. (ELSEVIER, 2025-03)
  • Development and validation of the Neuro-Score: a specific scale to detect and monitor cognitive impairment in kidney or liver transplant recipients 
    Moreso, Francesc; Minano, Jose Antonio Pons; Fructuoso, Ana Sanchez; Jacas, Carlos; Alegret, Montserrat; Ferrer, Montserrat; Colmenero, Jordi; Belmonte, Amado Andres; Jimenez, Veronica Lopez; Pascual, Sonia; Blanca, Auxiliadora Mazuecos; Galiano, Ana Paz Ventura; Cachero, Alba; Rivero, Antonio; Crespo, Marta; Cuadrado, Antonio; Marcos, Arantxa Caballero; Dieguez, Maria Luisa Gonzalez; Alvarez, Carolina Almohalla; Kareaga, Naroa Maruri; Martinez, Jose M. Alamo; Pagano, Giulia; Santana, Enriqueta Nuno; Torres, Irina B.; Flores, Isabel Perez; Alonso-Titos, Juana; Rodriguez-Soler, Maria; Alarcon, Laura Martinez; Alvarez, Teresa Maria Garcia; Castello, Isabel Beneyto; Gonzalez-Vilatarsana, Emma; Miras, Francesc; Bravo, Miguel Angel Gomez (ELSEVIER SCIENCE INC, 2025-05)
    We created and validated the Neuro-Score, a specific scale to detect and monitor cognitive impairment, including mild stages, in kidney or liver transplant recipients. A qualitative study was conducted to define a preliminary ...
  • Measuring the impact of hospitalization for infectious diseases on the quality of life of older patients in four European countries: the AEQUI longitudinal matched cohort study (2020-2023) 
    Veronese, Nicola; Polidori, Maria Cristina; Maggi, Stefania; Zamora, Javier; Ruiz-Calvo, Gabriel; Bangert, Mathieu; Bourron, Pierre; Bausch, Annika; Aviles-Hernandez, Juan Dionisio; Lopez-Soto, Alfonso; Padronguillen, Daniel; Lanoix, Jean-Philippe; Cruz-Jentoft, Alfonso J.; Gavazzi, Gaetan (ELSEVIER SCI LTD, 2025-05)
    OBJECTIVES: To evaluate the impact of hospitalization for infectious diseases on the Health-Related Quality of life (HRQOL), multidimensional frailty, and functioning of older patients, we conducted a longitudinal matched ...
  • Nature or nurture: genetic and environmental predictors of adiposity gain in adults 
    Peruchet-Noray, Laia; Dimou, Niki; Córdova, Reynalda; Fontvieille, Emma; Jansana, Anna; Gan, Quan; Breeur, Marie; Baurecht, Hansjoerg; Bohmann, Patricia; Konzok, Julián; Stein, Michael-J; Dahm, Christina-C; Zilhao, Nuno-R; Mellemkjaer, Lene; Tjonneland, Anne; Kaaks, Rudolf; Katzke, Verena; Inan-Eroglu, Elif; Schulze, Matthias-B; Masala, Giovanna; Sieri, Sabina; Simeon, Vittorio; Matullo, Giuseppe; Molina-Montes, Esther; Amiano, Pilar; Chirlaque-López, María-Dolores; Gasque, Alba; Atkins, Joshua; Smith-Byrne, Karl; Ferrari, Pietro; Viallon, Vivian; Agudo, Antonio; Gunter, Marc-J; Bonet, Catalina; Freisling, Heinz; Carreras-Torres, Robert (ELSEVIER, 2025-01)
    BACKGROUND: Previous prediction models for adiposity gain have not yet achieved sufficient predictive ability for clinical relevance. We investigated whether traditional and genetic factors accurately predict adiposity ...
  • Assessment of satisfaction level with an electronic referral system between Primary Care and Cardiology. 
    Fernández-Villa, Noelia; Nieto-López, Alberto; Sánchez-López, María-Isabel; Manzano-Fernández, Sergio (ELSEVIER, 2025-04)
  • Endothelial activation, cell-cell interactions, and inflammatory pathways in postoperative atrial fibrillation following cardiac surgery 
    López-Gálvez, Raquel; Rivera-Caravaca, José-Miguel; Mandaglio-Collados, Dario; Ruiz-Alcaraz, Antonio-José; Lahoz-Tornos, Álvaro; Hernández-Romero, Diana; Orenes-Piñero, Esteban; Ramos-Bratos, María-Pilar; Martínez, Carlos-M; Carpes, Marina; Arribas-Leal, José-María; Cánovas-López, Sergio; Lip, Gregory-Y-H; Marín, Francisco (ELSEVIER, 2025-08)
    BACKGROUND: Postoperative atrial fibrillation (POAF) is common after cardiac surgery and related to endothelial activation and systemic inflammation. Herein, we investigate the pathophysiological mechanisms of AF through ...

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