Repositorio Dspace

Listar03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla) por tema "Animals"

Listar03. IMIB (Instituto Murciano de Investigación Biosanitaria Pascual Parrilla) por tema "Animals"

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  • Arriazu, Elena; Vicente, Carmen; Pippa, Raffaella; Peris, Irene; Martínez-Balsalobre, Elena; García-Ramírez, Patricia; Marcotegui, Nerea; Igea, Ana; Alignani, Diego; Rifon, José; Mateos, María-C; Cayuela, María-Luisa; Nebreda, Ángel-R; Odero, María-D (NATURE PUBLISHING GROUP, 2020-01-08)
    Acute myeloid leukemia (AML) is an aggressive hematologic malignancy. Although novel emerging drugs are available, the overall prognosis remains poor and new therapeutic approaches are required. PP2A phosphatase is a key ...
  • Adriouch, Sahil; Pelegrin, Pablo (John Wiley and Sons Inc, 2022)
    Inflammasomes are multiprotein complexes that signal by oligomerizing the apoptosis speck-like protein with caspase recruitment and activator domain (ASC) and are involved in multiple inflammatory, metabolic and degenerative ...
  • López-Berenguer, G; Acosta-Dacal, A; Luzardo, OP; Peñalver, J; Martínez-López, E (Elsevier Ltd, 2023)
    Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants. Although they are not bioaccumulated in vertebrates, chronic exposures might still derive on serious toxic effects. We studied concentrations ...
  • Martín-Cortazar, Carla; Chiodo, Yuri; Jiménez-P, Raul; Bernabé, Manuel; Cayuela, María-Luisa; Iglesias, Teresa; Campanero, Miguel-R (FERRATA STORTI FOUNDATION, 2020-03-01)
    Metastases, the major cause of death from cancer, require cells' acquisition of the ability to migrate and involve multiple steps, including local tumor cell invasion and basement membrane penetration. Certain lymphoid ...
  • Di-Pierdomenico, Johnny; Martínez-Vacas, Ana; Hernández-Muñoz, Daniel; Gómez-Ramírez, Ana-M; Valiente-Soriano, Francisco-Javier; Agudo-Barriuso, Marta; Vidal-Sanz, Manuel; Villegas-Pérez, María-Paz; García-Ayuso, Diego (ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2020-03)
    PURPOSE: To analyze the role of microglial and Müller cells in the formation of rings of photoreceptor degeneration caused by phototoxicity. METHODS: Two-month-old Sprague-Dawley rats were exposed to light and processed ...
  • Bruguier, Hannah; Suárez, Rodrigo; Manger, Paul; Hoerder-Suabedissen, Anna; Shelton, Andrew-M; Oliver, David-K; Packer, Adam-M; Ferran, José-L; García-Moreno, Fernando; Puelles, Luis; Molnar, Zoltan (WILEY, 2020-12-01)
    The human claustrum, a major hub of widespread neocortical connections, is a thin, bilateral sheet of gray matter located between the insular cortex and the striatum. The subplate is a largely transient cortical structure ...
  • Martínez-Fresneda, L; O'Brien, E; López-Sebastian, A; Velazquez, R; Toledano-Diaz, A; Tesfaye, D; Schellander, K; García-Vázquez, F-A; Santiago-Moreno, J (ELSEVIER SCIENCE INC, 2020-07)
    In small ruminants, testosterone and prolactin plasma concentrations show circannual fluctuations as an adaptation mechanism to their seasonal breeding behavior. Sperm resistance to the freezing-thawing process shows ...
  • Bano-Otalora, Beatriz; Madrid, Juan-Antonio; Angeles-Rol, María (WILEY, 2020-01)
    Modern 24-h society lifestyle is associated with experiencing frequent shifts in the lighting conditions which can negatively impact human health. Here, we use the degus, a species exhibiting diurnal and nocturnal chronotypes, ...
  • Guerrero-Gironés, Julia; Alcaina-Lorente, Antonia; Ortiz-Ruiz, Clara; Ortiz-Ruiz, Eduardo; Pecci-Lloret, María-P; Rodríguez-Lozano, Francisco-Javier; Martínez, Carlos-M; Ortiz-Ruiz, Antonio-José (MDPI, 2020)
    Melatonin plays an essential role in the regulation of bone growth. The actions that melatonin exerts on odontoblasts may be similar to its action on osteoblasts. This research aimed to evaluate the pulp response to melatonin ...
  • Alburquerque-González, Begoña; Bernabé-García, Manuel; Montoro-García, Silvia; Bernabé-García, Ángel; Rodrigues, Priscila-Campioni; Ruiz-Sanz, Javier; López-Calderón, Fernando-F; Luque, Irene; Nicolas, Francisco-José; Cayuela, María-Luisa; Salo, Tuula; Pérez-Sánchez, Horacio; Conesa-Zamora, Pablo (SPRINGERNATURE, 2020-02)
    Serrated adenocarcinoma (SAC) is more invasive, has worse outcomes than conventional colorectal carcinoma (CRC), and is characterized by frequent resistance to anti-epidermal growth factor receptor (EGFR) and overexpression ...
  • Cuenca-Zamora, Ernesto-José; Martínez, Constantino; Morales, María-Luz; Guijarro-Carrillo, Pedro-Jesús; López-Poveda, María-José; Alcolea-Guardiola, Carlos; Vidal-Garrido, Natalia; Lozano, María-Luisa; Gonzalez-Conejero, Rocío; Teruel-Montoya, Raúl; Ferrer-Marín, Francisca (Elsevier Masson s.r.l., 2024)
    Chronic proinflammatory signaling is a characteristic trait in myeloproliferative neoplasms (MPN), particularly myelofibrosis (MF). Aberrant inflammatory signaling, particularly from NF-?B pathway, exacerbates the progression ...
  • Solano, Francisco (MDPI, 2020-04)
    Direct sun exposure is one of the most aggressive factors for human skin. Sun radiation contains a range of the electromagnetic spectrum including UV light. In addition to the stratospheric ozone layer filtering the most ...
  • Liarte, Sergio; Bernabé-García, Ángel; Nicolas, Francisco-J (MDPI, 2020-02)
    Chronic wounds are characterized for their incapacity to heal within an expected time frame. Potential mechanisms driving this impairment are poorly understood and current hypotheses point to the development of an unbalanced ...
  • Rodríguez-Alonso, Beatriz; Maillo, Verónica; Salvador-Acuna, Omar; López-Ubeda, Rebeca; Torrecillas, Alejandro; Simintiras, Constantine-A; Sturmey, Roger; Aviles, Manuel; Lonergan, Patrick; Rizos, Dimitrios (MDPI, 2020-03)
    Knowledge of how the biochemical composition of the bovine oviduct is altered due to the oviduct anatomy or the presence of an embryo is lacking. Thus, the aim of this study was to assess the effect of (?) oviduct anatomy ...
  • Tong, Tammy-Y-N; Appleby, Paul-N; Key, Timothy-J; Dahm, Christina-C; Overvad, Kim; Olsen, Anja; Tjonneland, Anne; Katzke, Verena; Kuhn, Tilman; Boeing, Heiner; Karakatsani, Anna; Peppa, Eleni; Trichopoulou, Antonia; Weiderpass, Elisabete; Masala, Giovanna; Grioni, Sara; Panico, Salvatore; Tumino, Rosario; Boer, Jolanda-M-A; Verschuren, W-M-Monique; Quiros, J-Ramon; Agudo, Antonio; Rodríguez-Barranco, Miguel; Imaz, Liher; Chirlaque-López, María-Dolores; Moreno-Iribas, Conchi; Engstrom, Gunnar; Sonestedt, Emily; Lind, Marcus; Otten, Julia; Khaw, Kay-Tee; Aune, Dagfinn; Riboli, Elio; Wareham, Nicholas-J; Imamura, Fumiaki; Forouhi, Nita-G; di-Angelantonio, Emanuele; Wood, Ángela-M; Butterworth, Adam-S; Pérez-Cornago, Aurora (OXFORD UNIV PRESS, 2020-07-21)
    AIM: To investigate the associations between major foods and dietary fibre with subtypes of stroke in a large prospective cohort. METHODS AND RESULTS: We analysed data on 418 329 men and women from nine European countries, ...
  • Ramírez, Ana; de-Hoz, Rosa; Fernández-Albarral, José-A; Salobrar-García, Elena; Rojas, Blanca; Valiente-Soriano, Francisco-Javier; Aviles-Trigueros, Marcelino; Villegas-Pérez, María-Paz; Vidal-Sanz, Manuel; Trivino, Alberto; Ramírez, José-M; Salazar, Juan-J (NATURE PORTFOLIO, 2020-03-17)
    Microglial activation is associated with glaucoma. In the model of unilateral laser-induced ocular hypertension (OHT), the time point at which the inflammatory process peaks remains unknown. Different time points (1, 3, ...

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