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Envíos recientes

Repositorio Institucional en Ciencias de la Salud de la Región Murcia: Envíos recientes

  • Neoadjuvant Abemaciclib plus Letrozole vs. Chemotherapy in patients with HR+/HER2- Highly Proliferative Breast Cancer. 
    Martin, Miguel; Guerrero-Zotano, Ángel; Pérez-López, María-E; Ruiz-Borrego, Manuel; Martínez-Janez, Noelia; Chacon, José-I; Gil-Gil, Miguel; Andrés, Raquel; Bermejo, Begoña; Sánchez-Rovira, Pedro; Del-Barco, Sonia; Ponce, José-J; Fernández, Isaura; Martínez-de-Duenas, Eduardo; Hinojo-Gonzale, Carmen; González, Marta; García-Garre, Elisa; Hernando, Blanca; de-la-Haba-Rodríguez, Juan; Álvarez, Isabel-M; González-Santiago, Santiago; García-Saenz, José-A; Santaballa, Ana; Casas, Maribel; Bezares, Susana; Caballero, Rosalía; Rojo, Federico; Alba, Emilio (AACR JOURNALS, 2026-01-22)
    PURPOSE: Neoadjuvant chemotherapy is standard for high-risk hormone receptor-positive and human epidermal growth factor receptor 2-negative (HR+/HER2-) breast cancer. This study evaluates whether 12 months of letrozole ...
  • Cabozantinib plus Atezolizumab in Advanced, Progressive Endocrine Malignancies: A Multicohort, Basket, Phase II Trial (CABATEN/GETNE-T1914) 
    Capdevila, Jaume; Hernando, Jorge; Molina-Cerrillo, Javier; Benavent-Vinuales, Marta; García-Carbonero, Rocío; Teule, Alex; Custodio, Ana; Jiménez-Fonseca, Paula; López, Carlos; Hierro, Cinta; Carmona-Bayonas, Alberto; Alonso, Vicente; Llanos, Marta; Sevilla, Isabel; García-Álvarez, Alejandro; Alonso-Gordoa, Teresa; Gallego-Jiménez, Inmaculada; Antón-Pascual, Beatriz; Modrego-Sánchez, Andrea; Grande, Enrique (AMER ASSOC CANCER RESEARCH, 2025-11-14)
    PURPOSE: Multikinase inhibitors have shown efficacy in endocrine neoplasms, and synergism with immune checkpoint inhibitors has been noted in other tumors. PATIENTS AND METHODS: This is a prospective, multicenter, open-label, ...
  • FOXC1 Expression Predicts Capecitabine Efficacy in Patients with Triple-Negative Breast Cancer from the GEICAM_CIBOMA Trial 
    Rojo, Federico; Taylor, Clive-R; Barrios, Carlos; Torrecillas, Laura; Ruiz-Borrego, Manuel; Pérez-Buira, Sandra; Bines, José; Guerrero-Zotano, Ángel; García-Saenz, José-A; Torres, Roberto; de-la-Haba-Rodríguez, Juan; Ayala-de-la-Peña, Francisco; Gómez, Henry; Llombart, Antonio; Rodríguez-de-la-Borbolla, María; Baena-Canada, José-Manuel; Barnadas, Agusti; Calvo, Lourdes; Herranz, Jesús; Rincon, Raúl; Caballero, Rosalía; Bermejo, Begoña; Ray, Partha-S; Martin, Miguel (AMER ASSOC CANCER RESEARCH, 2025-09-02)
    PURPOSE: In a prespecified GEICAM_CIBOMA trial (NCT00130533) correlative analysis, PAM50 non-basal-like breast cancer (non-BLBC) status distinguished patients with triple-negative breast cancer (TNBC) who are most likely ...
  • Evaluation of the 4Kscore Test in Relation to Subsequent Risk of Aggressive Prostate Cancer in the European Prospective Investigation into Cancer and Nutrition 
    Smith-Byrne, Karl; Fensom, Georgina-K; Noor, Urwah; Watts, Eleanor-L; Allen, Naomi-E; Amiano, Pilar; Chirlaque-López, María-Dolores; Crous-Bou, Marta; Guevara-Eslava, Marcela; Palli, Domenico; Katzke, Verena-A; Sacerdote, Carlotta; Sánchez, María-José; Schulze, Matthias-B; Sieri, Sabina; Tumino, Rosario; Tsilidis, Konstantinos-K; Kaaks, Rudolf; Gunter, Marc-J; Riboli, Elio; Key, Timothy-J; Travis, Ruth-C (AMER ASSOC CANCER RESEARCH, 2025-11-03)
    BACKGROUND: PSA is central to referrals for prostate biopsy but has low specificity for aggressive prostate cancer. This study evaluates the 4Kscore (OPKO Diagnostics) versus total PSA in predicting short- and long-term ...
  • Real-World Impact of Calcipotriol/Betamethasone Dipropionate Aerosol Foam on Quality of Life in Patients With Plaque Psoriasis: A Prospective Observational Study 
    Torres, Tiago; Martorell, Antonio; Leal-Filipe, Paulo; Soria, Caridad; Mota, Fernando; Pardo, José; Ribera, Miquel; Ruiz-Villaverde, Ricardo (WILEY, 2025-01)
  • Fatigue, Physical Symptoms, Psychological Distress, and Use of Integrative Medicine in Patients With Advanced Cancer 
    Calderón, Caterina; Muñoz-Sánchez, M-Mar; Peña-López, Jesús; López-Ceballos, M-Helena; Fernández-Montes, Ana; Asensio-Martínez, Elena; Carrillo-Vicente, Raul; Gustems, Marina; Jiménez-Fonseca, Paula (WILEY, 2025-01)
  • Adding Docetaxel to Tepotinib to Overcome Oligoprogression in MET Exon 14 Skipping-Mutated NSCLC When Local Therapy Is Unfeasible: A Case Report 
    Sánchez-García, David; Grau-Mirete, Beatriz; Rodríguez-Payá, Paula; Ferrandez-Arias, Asia; Borregón-Rivilla, Miguel; Lázaro-Sánchez, Antonio-David; Benítez-Fuentes, Javier-David (WILEY, 2025-01)
    Oligoprogression in MET Exon 14 skipping (METex14)-mutated non-small cell lung cancer (NSCLC) is clinically challenging, particularly when local therapies are contraindicated. We report the first documented case of a ...
  • Chemical Optimization of Cerebral Embolectomy 2 (CHOICE 2) trial: study protocol 
    Renu, Arturo; de-la-Riva, Patricia; Delgado-Mederos, Raquel; Dorado, Laura; Fernández-Couto, María-Dolores; Herrera-Isasi, María; López-Hernández, Nicolas; Morales, Ana; Morales-Caba, Lluis; Camps-renom, Pol; Singla, Alba; Terceno, Mikel; Vega, Pedro; Amaro, Sergio; Blasco, Jordi; Laredo, Carlos; Leira, Enrique-C; Oleaga, Laura; Serena, Joaquín; Urra, Xabier; Werner, Mariano; Hernández-Fernández, Francisco; Valls, Joan; Arenillas-Lara, Juan-Francisco; Freijo, María-Del-Mar; Pérez-de-la-Ossa, Natalia; San-Roman, Luis; Torres, Ferran; Castellanos, Mar; Davalos, Antonio; Chamorro, Ángel (BMJ PUBLISHING GROUP, 2025-12-03)
    RATIONALE: The potential value of rescue intra-arterial thrombolysis in patients with large vessel occlusion (LVO) stroke treated with mechanical thrombectomy (MT) remains to be validated in randomised trials. AIM: The ...
  • Seventeen-year reassessment of diagnostic transitions, biologic therapy initiation and mortality in spondyloarthritis: results from the REGISPON-3 study 
    Puche-Larrubia, María-Ángeles; Ladehesa-Pineda, Lourdes; Abalos-Aguilera, María-Carmen; Ruiz-Vilchez, Desiree; Berbel-Arcobe, Laura; Juanola-Roura, Xavier; Arévalo-Salaet, Marta; Moreno, Mireia; Almodovar-González, Raquel; Pijoan-Moratalla, Cristina; Joven-Ibáñez, Beatriz; Valero-Exposito, Marta; García-García, Veronica; Moreno-Ramos, Manuel-José; Ornilla, Enrique; Granados, Raquel-Ena-María; Moldovan, Diana-María-Margareta; Collantes-Sánchez, Carlos-M; Escudero-Contreras, Alejandro; Collantes-Estevez, Eduardo; López-Medina, Clementina (BMJ PUBLISHING GROUP, 2025-10)
    OBJECTIVES: To evaluate disease evolution, diagnostic transitions, time to biologic treatment initiation and mortality in patients with spondyloarthritis (SpA) after 17 years from the original Spanish Registry of ...
  • Impact of physical activity on presentation and prognosis of Brugada syndrome 
    Fernández-Gil, María-Jesús; Carrillo-Mora, Lidia-María; Fernández-Vázquez, David; Melgarejo-Meseguer, Francisco-Manuel; Santos-Mateo, Juan-José; Muñoz-Esparza, Carmen; Rodríguez-Serrano, Ana-Isabel; Navarro-Peñalver, Marina; Sánchez-Muñoz, Juan-José; Gimeno-Blanes, Juan-Ramón; Sabater-Molina, María; Gimeno-Blanes, Juan-Ramón (BMJ PUBLISHING GROUP, 2025-07)
    INTRODUCTION AND OBJECTIVES: Brugada syndrome (BS) is a channelopathy associated with an increased risk of sudden cardiac death (SCD). Intense physical activity is a recognised trigger of life-threatening arrhythmias in ...
  • Hypertrophic cardiomyopathy and atrial fibrillation: the Cardiomyopathy/Myocarditis Registry of the EURObservational Research Programme of the European Society of Cardiology 
    Mizia-Stec, Katarzyna; Gimeno-Blanes, Juan-Ramón; Charron, Philippe; Elliott, Perry-M; Kaski, Juan-Pablo; Maggioni, Aldo-Pietro; Tendera, Michal; Tavazzi, Luigi; Wybraniec, Maciej-T; Laroche, Cecile; Caforio, Alida; EORP-Cardiomyopathy-Registry-Investigators (BMJ PUBLISHING GROUP, 2025-01)
    BACKGROUND: Hypertrophic cardiomyopathy (HCM) is commonly associated with atrial fibrillation (AF), but its impact on outcomes in real-world practice is uncertain. The aim of the study was to evaluate the clinical profile ...
  • Validation of proposals for definitions of moderate and severe disease activity in SLE: impact on flares, quality of life, damage accrual, hospitalisations and mortality 
    Altabas-González, Irene; Rua-Figueroa, Íñigo-Jesús; Roberts, Karen; Mamani, Ivonne-Lourdes; Mourino, Coral; Martínez-Barrio, Julia; Galindo-Izquierdo, María; Calvo-Alen, Jaime; Erausquin, Celia; Serrano-Benavente, Belén; Uriarte, Esther; Tomero, Eva; Freire-González, Mercedes; Blanco, Ricardo; Salgado, Eva; Gómez-Sabater, Silvia; Fernández-Nebro, Antonio; Sanguesa, Clara; Narváez, Javier; Mena-Vázquez, Natalia; Menor-Almagro, Raúl; Rosas-Gómez-de-Salazar, José-Carlos; Aurrecoechea, Elena; Ibarguengoitia-Barrena, Oihane; Montilla, Carlos; Bonilla, Gema; Torrente-Segarra, Vicente; Juan-Mas, Antonio; García-Villanueva, María-Jesús; Moriano-Morales, Claudia; Horcada, Loreto; Lozano-Rivas, Nuria; Iniguez, Carlota; Arévalo, Marta; Paredes, Beatriz; Expósito, Lorena; Toyos, Francisco-J; Flores-Fernández, Eduardo; Novoa-Medina, Javier; Fragio-Gil, Jorge-Juan; Bohorquez, Cristina; Pego-Reigosa, José-María (BMJ PUBLISHING GROUP, 2025-07)
    INTRODUCTION: Accurate assessment of disease activity in SLE is crucial but challenging due to its varied clinical manifestations and severity. Current tools like the SLE Disease Activity Index (SLEDAI) have limitations, ...
  • Comorbidity clusters and their relationship with severity and outcomes of index diseases, in a large multicentre systemic lupus erythematosus cohort 
    Rua-Figueroa, Íñigo-Jesús; Pérez-Veiga, Natalia; Rodríguez-Almaraz, Esther; Galindo-Izquierdo, María; Erausquin, Celia; Fernández-Nebro, Antonio; Uriarte-Itzazelaia, Esther; Serrano-Benavente, Belén; Calvo-Alen, Jaime; Manrique-Arija, Sara; Senabre, José-M; Bernal, José-A; Narváez, Javier; Tomero, Eva; Aurrecoechea, Elena; Ibáñez-Barcelo, Mónica; Torrente-Segarra, Vicente; Sanguesa, Clara; Freire-González, Mercedes; García-Villanueva, María-Jesús; Martínez-Taboada, Victor; Arévalo, Marta; Moriano-Morales, Claudia; Iniguez, Carlota; Pérez, Ana; Salgado, Eva; Carrion-Barbera, Irene; Andreu, José-L; Cobo, Tatiana; Horcada, Loreto; Bonilla, Gema; Lozano-Rivas, Nuria; Expósito, Lorena; Montilla, Carlos; Toyos, Francisco-J; Ibarguengoitia-Barrena, Oihane; Valls-Pascual, Elia; Novoa-Medina, Javier; Menor-Almagro, Raúl; Roman-Ivorra, José-Andrés; Muñoz-Jiménez, Alejandro; Nolla, Joan-M; Pego-Reigosa, José-María (BMJ PUBLISHING GROUP, 2025-07)
    OBJECTIVE: Patients with SLE have a well-known increased risk of major comorbidities, although they are also very heterogeneous in terms of the prevalence of comorbid conditions. The relationships of such comorbidities ...
  • Oral glucocorticoid patterns use in moderate to severe active SLE: insights from the Spanish SPOCS data 
    Rua-Figueroa, Íñigo-Jesús; Cervera, Ricard; Freire-González, Mercedes; Turrión-Nieves, Ana-Isabel; Cortés-Hernández, Josefina; Castellvi, Iván; Ajo, Julia-Barbado; Salman, Tarek; Calvo-Alen, Jaime; Lozano-Rivas, Nuria; Ortego-Centeno, Norberto; Díaz-Encarnacion, Monserrat; Ding, Bo; Galvez-Fernández, Marta; Bahamontes-Rosa, Noemi; Pego-Reigosa, José-María; Spanish-SLE-Prospective-Observational-Cohort-Study-SPOCS (BMJ PUBLISHING GROUP, 2025-07)
  • Hydroxychloroquine in patients with systemic lupus erythematosus: how much is enough? 
    Ruiz-Irastorza, Guillermo; Paredes-Ruiz, Diana; Arizpe, Fernando; Campos-Rodríguez, Valerio; Moreno-Torres, Victor; Amo, Laura; Ruiz-Arruza, Ioana; Martín-Iglesias, Daniel (BMJ PUBLISHING GROUP, 2025-02)
    OBJECTIVE: To assess the daily and weight-adjusted dosages of hydroxychloroquine (HCQ) and the effects on long-term remission in the Lupus-Cruces cohort. METHODS: Observational study of routine clinical care data. We ...
  • Efficacy and safety of the PHIL embolic agent in the treatment of intracranial dural arteriovenous fistulas: results of the PHIL-dAVF study 
    Marnat, Gaultier; Barreau, Xavier; Januel, Anne-Christine; Spelle, Laurent; Piotin, Michel; Mounayer, Charbel; Borota, Ljubisa; González, Alejandro; Casasco, Alfredo; Keston, Peter; Lobotesis, Kyriakos; Cronqvist, Mats; Holtmannspotter, Markus; Guimaraens, Leopoldo; Boccardi, Edoardo; Valvassori, Luca; Espinosa-de-Rueda, Mariano; Cognard, Christophe; PHIL-DAVF-Study-Investigators (BMJ PUBLISHING GROUP, 2026-01)
    BACKGROUND AND PURPOSE: Embolization is the first-line treatment for dural arteriovenous fistulas (dAVF). The precipitating hydrophobic injectable liquid (PHIL) embolic agent is a non-adhesive copolymer with specific ...
  • Does lifestyle explain the relationship between socioeconomic position and multimorbidity of cancer and cardiometabolic diseases? A mediation analysis applied to the European Prospective Investigation into Cancer and Nutrition 
    Manfredi, Luca; Buscema, Federica; Giraudo, María-Teresa; Sodano, Barbara; Padroni, Lisa; Destefanis, Cinzia; Freisling, Heinz; Ferrari, Pietro; Cesaroni, Giulia; Uzzau, Sergio; Schulze, Matthias-B; Saieva, Calogero; Tumino, Rosario; Weiderpass, Elisabete; Matta, Komodo; Vaccarella, Salvatore; Guevara, Marcela; Halkjaer, Jytte; Tjonneland, Anne; Crous-Bou, Marta; Katzke, Verena; Pour, Toktam; Panico, Salvatore; Pala, Valeria; Tzoulaki, Ioanna; Tin-Tin, Sandar; Dahm, Christina-C; Chirlaque-López, María-Dolores; Sacerdote, Carlotta; Ricceri, Fulvio (BMJ PUBLISHING GROUP, 2026-01)
    BACKGROUND: Multimorbidity is socially patterned, with lower socioeconomic position (SEP) linked to higher risk. We examined whether a Healthy Lifestyle Index (HLI) mediates the SEP-multimorbidity association and whether ...
  • Examining causal relationships between educational attainment and type 2 diabetes using genetic analysis: findings from the EPIC-InterAct study through Mendelian randomisation 
    Macciotta, Alessandra; Sacerdote, Carlotta; Giachino, Claudia; Di-Girolamo, Chiara; Franco, Matteo; van-der-Schouw, Yvonne-T; Zamora-Ros, Raúl; Weiderpass, Elisabete; Domenighetti, Cloe; Elbaz, Alexis; Truong, Therese; Agnoli, Claudia; Bendinelli, Benedetta; Panico, Salvatore; Vineis, Paolo; Christakoudi, Sofia; Schulze, Matthias-B; Katzke, Verena; Bajracharya, Rashmita; Dahm, Christina-C; Dalton, Susanne-Oksbjerg; Colorado-Yohar, Sandra; Moreno-Iribas, Conchi; Amiano-Etxezarreta, Pilar; Sánchez, María-José; Forouhi, Nita-G; Wareham, Nicholas; Ricceri, Fulvio (BMJ PUBLISHING GROUP, 2025-05)
    INTRODUCTION: Observational studies have shown that more educated people are at lower risk of developing type 2 diabetes (T2D). However, robust study designs are needed to investigate the likelihood that such a relationship ...
  • Intrahepatic donor microbiota-based metataxonomic signature detected in organ preservation solution enables prediction of short-term liver transplant outcomes 
    Lucas-Ruiz, Fernando; Vidal-Correoso, Daniel; V; de-la-Torre-Álamo, María-Magdalena; Jover-Aguilar, Marta; Alconchel-Gago, Felipe; Martínez-Alarcón, Laura; López-López, Víctor; Ríos-Zambudio, Antonio; Cascales-Campos, Pedro-Antonio; Pelegrín, Pablo; Pons-Miñano, José-Antonio; Ramírez, Pablo; Baroja-Mazo, Alberto (BMJ PUBLISHING GROUP, 2025-12)
    BACKGROUND: Liver transplantation (LT) remains hampered by post-transplant complications. While gut microbiota dysbiosis has been linked to transplant outcomes, the role of the intrahepatic graft's native microbiota remains ...
  • Withdrawal of antitumour necrosis factor in inflammatory bowel disease patients in remission: a randomised placebo-controlled clinical trial of GETECCU 
    Gisbert, Javier-P; Donday, María-G; Riestra, Sabino; Lucendo, Alfredo-J; Benítez, José-Manuel; Navarro-Llavat, Merce; Barrio, Jesús; Morales-Alvarado, Víctor-J; Rivero, Montserrat; Busquets, David; Leo-Carnerero, Eduardo; Merino, Olga; Nantes-Castillejo, Oscar; Navarro, Pablo; Van-Domselaar, Manuel; Gutiérrez, Ana; Alonso-Abreu, Inmaculada; Mejuto, Rafael; Fernández-Salazar, Luis; Iborra, Marisa; Martín-Arranz, María-Dolores; Pineda, Juan-Ramón; Sampedro, Manuela-Josefa; Serra-Nilsson, Katja; Bouhmidi, Abdel; Batista, Lissette; Muñoz-Villafranca, Carmen; Rodríguez-Lago, Iago; Ceballos, Daniel; Guerra, Iván; Manosa, Miriam; Marín-Jiménez, Ignacio; Torrella-Cortés, Emilio; Vera-Mendoza, Maribel; Casanova, María-José; de-Francisco, Ruth; Arias-González, Laura; Marín-Pedrosa, Sandra; García-Bosch, Orlando; García-Alonso, Francisco-Javier; Delgado-Guillena, Pedro; García, María-José; Torrealba, Leyanira; Núñez-Ortiz, Andrea; Vicuna-Arregui, Miren; Bosca-Watts, Marta-Maia; Blázquez, Isabel; Acosta, Diana; Garre, Ana; Baldan, Montse; Martínez, Concepción; Barreiro-de-Acosta, Manuel; Domenech, Eugeni; Esteve, María; García-Sánchez, Valle; Nos, Pilar; Panes, Julián; Chaparro, María (BMJ PUBLISHING GROUP, 2025-03)
    BACKGROUND AND OBJECTIVES: Primary objectives: to compare the rates of sustained clinical remission at 12 months in patients treated with antitumour necrosis factor (anti-TNF) and immunomodulators who withdraw anti-TNF ...